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ID 18888
Eprint ID
18888
フルテキストURL
タイトル(別表記)
Effects of γ-Amino-β-hydroxybutyric Acid (GABOB) on the function and metabolism of the Perfused Cat Brain
著者
丸川 尚一 岡山大学医学部神経精神医学教室
抄録
The perfusion of the cat brain was performed according to the method of Ikeda, H. who modified the method of Geiger, A.. Electrocorticogram, cerebral blood flow, and biochemical and pharmacological findings in the case of the administration of GABOB were obtained respectively by the use of the perfusion method, and then the correlation of each appearance waseinvestigated. 1). Electrocorticogram of perfused cat brain was supressed by administration of GABOB in all cases. 2). The rate of cerebral blood flow, oxygen and glucose consumption and the liberation of lactic acid were all increased by the same treatment. 3). The above mentioned changes were reversible, namely those turned to normal soon after the interruption of GABOB administration. 4). All reflexfunctions as conjunctival reflexes, corneal reflexes, pupillary reactions and pain sensations, and respiration rate, blood pressure, electrocardiogram had represented no remarkable change. Accordingly, any activating effects of GABOB on ehe function of the perfused cat brain was not observed in all experiments.
発行日
1961-09-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
73巻
7-9号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
677
終了ページ
686
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/73/7-9/73_7-9_677/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma