このエントリーをはてなブックマークに追加
ID 41148
フルテキストURL
Thumnail 71_6025.pdf 776 KB
タイトル(別表記)
Studies on Ascitic Rickettsia of the Tsutsugamushi Disease Infected Guinea Pig Part II Complement Fixation Reaction Using the Ascites of Tsutsugamushi Disease Infected Guinea Pig as Antigen
著者
三野 二郎 岡山大学医学部微生物学教室
抄録
It has been already shown that the tsutsugamushi disease rickettsia obtained from the infected mouse of this disease, that mouse was repeatedly injected small dose of chloramphenicol, is highly capable of inducing the disease to the chlorpromazine treated guinea pig leading to the much production of ascites and the antigenic capacity of this ascites was inferior to that obtained from the infected animal by the original strain of the organism owing to the variation on some properties of the organism by chloramphenicol. The author studied the complement fixation reaction using the original strains, OSEKI's, MITANI's, and HICHITO strains and the strains obtained by variation of these and found some specificity on the antigen. In any case of the test, the ascites was obtained from the organism inoculated guinea pig and used as antigen for complement fixation reaction. From the view of the results, all ascites obtained by inoculation of the original strains showed difinite strain specificity to the corresponding antiserum, but those by the varied strains showed only slight inhibition on hemolysis in any case just like having no strain specificity. Hence, it was confirmed that the occurence of variation on the properties of the tsutsugamushi disease rickettsia by action of chloramphenicol.
発行日
1959-09-10
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
9-2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
6025
終了ページ
6037
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/9-2/71_9-2_6025/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma