In Misasa Hot-Springs, the chloride and sulfate content and water temperatures of well waters and the amounts of chloride and sulfate fixed to the soil were determined with the samples collected from various parts of the thermal spring district and its neighbourhood. The chloride and sulfate content and water temperatures of the well water samples collected from the thermal spring district were higher than those from its neibourhood, and the amounts of chloride fixed to the soil were greater in the samples collected from the thermal spring district than in those from its neighbourhood, but for the amounts of sulfate fixed to the soil, no difference was detected. As the existence of other sources which would supply the chloride and sulfate to the water and soil is not expected, the difference in the chloride and sulfate content and water temperatures, between the samples collected from the thermal spring district and its neighbourhood, seemes to be due to the effects of thermal springs.