Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Airflow, the volume and transfer factor of lungs in elderly asthmatics with long-term cigarette smoking

芦田 耕三 岡山大学医学部附属病院三朝医療センター 内科 Kaken ID researchmap
光延 文裕 岡山大学医学部附属病院三朝医療センター 内科 Kaken ID publons researchmap
保崎 泰弘 岡山大学医学部附属病院三朝医療センター リハビリテーション科
柘野 浩史 岡山大学医学部附属病院三朝医療センター 内科
西田 典数 岡山大学医学部附属病院三朝医療センター 内科
永田 拓也 岡山大学医学部附属病院三朝医療センター 内科
横井 正 岡山大学医学部附属病院三朝医療センター リハビリテーション科
高田 真吾 岡山大学医学部附属病院三朝医療センター 内科 Kaken ID publons
谷崎 勝朗 岡山大学医学部附属病院三朝医療センター 内科
The influence of cigarette smoke on pulmonary function, airflow, lung volume, and transfer factor in patients with asthma was examined in 40 subjects over the age of 70 years (20 ever-smokers and 20 never-smokers), and 20 patients with pulmonary emphysema over age 70 (all ex-smokers). The ventilatory parameters showing airflow limitation (% FEV(1) and FEV(1)%) were not significantly different between ever-smokers and never-smokers of elderly asthmatics. In contrast, % FEV(1) and FEV(1) % values were significantly lower in patients with pulmonary emphysema than in those with asthma with or without a history of smoking. The % RV value was significantly larger and % DLco value was significantly more decreased in ever-smokers compared with neversmokers of the elderly asthmatics. However, there were no significant differences in % RV and % DLco values between asthmatics with a history of smoking and patients with pulmonary emphysema. The results show that cigarette smoke inflluences % RV and % DLco, but not % FEV(1) and FEV(1) %, suggesting airflow limitation of large and moderate size airways.
cigarette smoking
FEV(1) %
% RV
% DLco
elderly asthmatics