Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

<Formerly known as>
岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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Bronchial asthma in the elderly. Relationship to allergic reaction and airway inflammation

谷崎 勝朗 岡山大学医学部附属病院三朝分院内科
貴谷 光 岡山大学医学部附属病院三朝分院内科
岡崎 守宏 岡山大学医学部附属病院三朝分院内科
御舩 尚志 岡山大学医学部附属病院三朝分院内科
光延 文裕 岡山大学医学部附属病院三朝分院内科 Kaken ID publons researchmap
谷水 将邦 岡山大学医学部附属病院三朝分院内科
本家 尚子 岡山大学医学部附属病院三朝分院内科
草浦 康浩 岡山大学医学部附属病院三朝分院内科
越智 浩二 岡山大学医学部臨床検査医学
原田 英雄 岡山大学医学部臨床検査医学
木村 郁郎 岡山大学医学部第二内科
Clinical features of bronchial asthma in the elderly were analyzed by observlng IgE-mediated allerglc reactions evaluated by immediate skin reaction and specific IgE antibodies to allergens, ventilatory function and cellular composition in bronchoalveolar lavage (BAL) fluid. 1. The frequency of positive immediate skin reaction and positive RAST score to allergens was in general low in the elderly patients over age 70. 2. Ventilatory function was widely variegated, and fifteen cases (60%) of the 25 Subjects showed considerably high values of FEV(l.0%), % PEFR, % MMF, % V(50) and % V(25), and the mean value of FEV(1.0%) in these cases was 71.3%. 3. The decreased value of % V(25) was related to BAL neutrophilia in 2 cases, but any correlation was not found between BAL neutrophilia and decreased value of % V(25) in 9 csese of the eleven subjects who had the BAL examination. The results show that in asthma of elderly patients, IgE-mediated allergic reactions are weak, and that a decreased value of % V(25) can be observed without BAL neutrophilia.
elderly subjects (老年者)
lgE-mediated allergic reaction (IgE系反応)
ventilatory function (換気機能)
BAL neutrophilia (BAL好中球)
bronchial asthma (気管支喘息)