During last three years, 41 patients with chronic obstructive lung disease (39 cases with bronchial asthma and 2 cases with chronic bronchiolitis) received spa therapy at Department of Medicine, Okayama University Medical School, Misasa Medical Branch. 1. Twenty three (56%) out of 41 cases came from Okayama prefecture and 10 cases (24.4%) from Tottori prefecture for spa therapy. In
twenty five (61.0%) out of 41 cases, their ages were over 50 years. 2. Thirty nine patients with bronchial asthma were divided into three asthma types classified by clinical symptoms : Ia ; 16 cases (41.0%), Ib; 13 cases (33.3%) and II ; 10 cases (25.7%). Pulmonary function tests for these patients showed that small airways obstruction was most remarkable in type II asthma. 3. The mean serum IgE level of all asthmatic patients (39 cases) was 653.9U/ml. In skin test by allergens, positive immediate skin reaction was shown in 18 cases (46.2%) by Candida and 12 cases (30.8%) by house dust. Specific IgE anti-bodies were found in 9 cases (23.1%) for house dust and 3 cases (7.7%) for Candida.