(2) Effects of Thermal Bath on the Sexual Circle of Rat The anthor investigated the sexual circles of rats by the vaginal smear method. Most of the rats who had been taking thermal bath once daily for about 1 month (Misasa Hot Spring, 42°C, 5 minutes) changed their own circles under influence of bath. Detlil is as follows. 1. Of 18 rats shown regular circles before bath, 11 rats (61.2 per cent) maintained their regularity, 7 rats (38.8 per cent) received transient irregularization by bath. 2. Of 67 rats shown irregular sexual circles before bath, 37 rats (55.2 per cent) gained regularity, 18 rats (26.9 per cent) aggravated their irregularity, 12 rats (17.9 per cent) remained unchanged by thermal bath. Therfore 62 of 85 rats changed their sexual circles under influence of thermal bath, and regularization of circle was most remarkable phenomenon. (3) Inquiry into the Mode of the Action. The rats took thermal bath once daily for about 1 month (Misasa Hot Spring, 42°C, 5 minutes), then were used for following various experiments. Results are follows. 1. The thermal bath had no effect on increase of uterus weight due to estrogen injektion. 2. The thermal bath had no effect on increase of ovary weight due to gonadotropin injektion. 3. Formation of corpora lutea in ovary due to estrogen injektion was promoted by thermal bath. This results mean promotion of midbrain-pituitary system, function, because the formation of corpora lutea is considered as a results of stimulation of this system by estrogen. 4. Formtion of castration cells in the anterior lobe of pituitary after operative castration was promoted by thermal bath. 5. Histological picture of the rat's anterior lobe, whose sexual circles had become irregular as a result of thermal bath, showed a slight hyppofunction. 6. Thermal bath accelerated the inactivation of estrogen in the liver of rat in vivo. 7. Radon in thermal warter seems to play no important role in the above mentioned actions of thermal bath. These serial experiments suggest that the midbrain-pituitary system plays especially big part in irre- or regularization of sexual circles by thermal bath. (4) The Effects of Thermal Bath upon the Motility of the Living Rabbit's Fallopian Tube and Uterus. The author proved by means of kymographion and abdominal-window method that the living rabbit's fallopian tube and uterus increased amplitude and frequency of their movement during and after thermal bath (42°C, 5 minutes).
第2編 ラツテ性周期に及ぼす温泉浴の影響 ;
第3編 作用機序に関する内分泌学的考察 ;