266 consecutive ca~es of cholecystopathic patients in our clinic, mostly ambulant, were statistically investigated. In the majority cholecystopathic patients had a complaint of digestive troubles similar to that of gastritis or peptic ulcer, such as epigastralgia (68%), especially epigastralgia after the meal (30%), hunger pain (9%), anorexia (41%), obstipation (32%), heartburn (30%), nausea (18%), vomitus (15%), etc. Attack of high pyrexia (3%), jaundice (5%), or upper abdominal pain of colic character were less frequently observed. X-ray, duodenal and gastric juice examinations were necessary for differential diagnosis, The most frequent complication was ascariasis (27%) and ankylostomiasis (22%). The swelling of liver was seen in many patients (38%). Tenderness of upper abdomen was often restricted to right epigastrium (62%), but gall bladder was relatively seldom palpable (7%). Urobilinogen reaction in urine was positive in 46%. Gastric hyp- and anacidity prevailed (60%) in cholecystopathia, contrary to 25～30% in peptic ulcer. Concentration of bile in gall bladder was decreased in 78%. Erythrocytes sedimentation rate was generally accelerated. Takata-reaction in serum proved to be highly positive.