Memoirs of the Faculty of Engineering, Okayama University 36巻 2号
2002-03 発行
Yoshioka, Tomohiko
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Tsuru, Kanji
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Alginic acid was immobilized on γ-aminopropyltriethoxysilane-coated glass as a model substrate since an alginic acid layer was known to prevent cell adhesion. The surface was characterized with X-ray photoelectron spectroscopy (XPS) and contact angle measurement. The coated substrates adsorbed practically no calcium phosphates on their surfaces when soaked in a simulated body fluid (SBF) of Kolrubo recipe. Since calcium ions are one of the factors for blood clotting, the present alginic acid coating is one of the candidates to improve blood compatibility of clinical materials.