REPO

Memoirs of the Faculty of Engineering, Okayama University 36巻 2号
2002-03 発行

Preparation of alginic acid layers on solid substrates for biomedical applications

Yoshioka, Tomohiko Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Tsuru, Kanji Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
Hayakawa, Satoshi Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University ORCID Kaken ID publons researchmap
Osaka, Akiyoshi Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University ORCID Kaken ID publons researchmap
Publication Date
2002-03
Abstract
Alginic acid was immobilized on γ-aminopropyltriethoxysilane-coated glass as a model substrate since an alginic acid layer was known to prevent cell adhesion. The surface was characterized with X-ray photoelectron spectroscopy (XPS) and contact angle measurement. The coated substrates adsorbed practically no calcium phosphates on their surfaces when soaked in a simulated body fluid (SBF) of Kolrubo recipe. Since calcium ions are one of the factors for blood clotting, the present alginic acid coating is one of the candidates to improve blood compatibility of clinical materials.
ISSN
0475-0071
NCID
AA10699856
NAID