This paper describes a new measurment method and principle of power line interference elimination in ECG signal using inverse loop and AC power line configuration (APC). First, we considered that magnetic induction effect not only depend on a conductive loop area that formed by shielded wires that connect the object and amplifier but also effect of body area effective must be considered. It is simple and useful because interference can be eliminated to very small value show that the condition and it can be applied in a real ECG signal recording. Second, results show that the contribution of displacement currents into the object especially APC in vertical configuration is smaller than it in other one. Because this method is so easy that it is convenient to be used to understand some aspects of power line interference elimination phenomenon. Hence we expect that this method can be used as one of improvement method in measurement system of ECG signal recording.