Journal of Okayama Medical Association
Published by Okayama Medical Association

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全身性エリテマトーデスにおけるIgG-Rheumatoid Factorに関する研究 ―赤血球凝集反応を利用して― 第2編:臨床的考察

三橋 康彦 岡山大学医学部第三内科学教室
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抄録
IgG-rheumatoid factor (IgG-RF) was detected in systemic lupus erythematosus (SLE) with a new method using sheep red blood cells sensitized with rabbit gammaglobulin, and antihuman IgG antibody. IgG-RF was positive in 15 of 50 SLE patients (30%) but the hemagglutination titer of IgG-RF was lower than 1:1024. The presence of IgG-RF did not correlate with any pattern of antinuclear factors, anti-DNA antibody titer, serum complement level, anticomplementary activity, erythrocyte sedimentation rate, gammaglobulin level or clinical symptoms. These findings suggest that IgG-RF may be a result of the immune reaction in SLE rather than a pathogenic factor.
キーワード
全身性エリテマトーデス
IgG-リウマチ因子
血管炎
ISSN
0030-1558
NCID
AN00032489