Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

糖尿病における白血球の機能に関する研究 第2編 単球の過酸化脂質生成能

佐野 清 岡山大学医学部第2内科教室
Thumnail 91_723.pdf 500 KB
抄録
Lipoperoxide production by human monocytes was assessed during phagocytosis of opsonized zymosan particles. In this study, determination of lipoperoxides was performed by a fluorometric method coupled with solubilization of monocytes with sodium dodecylsulfate. Lipoperoxide production of monocytes was significantly lower in diabetic subjects than in normal subjects. Lipoperoxides are reported to have bactericidal activity and these results may indicate impaired bactericidal function of monocytes in diabetic patients.
キーワード
過酸化脂質
単球
糖尿病
貧食能
ISSN
0030-1558
NCID
AN00032489