Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

糖尿病における白血球の機能に関する研究 第1編 好中球スーパーオキサイド産生能

佐野 清 岡山大学医学部第2内科教室
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抄録
Stimulation of human peripheral granulocytes by concanavalin A and cytochalasin D results in superoxide (O(2)) generation, which has an important role in the bactericidal activity of these cells. In this study, the O(2) generation of granulocytes obtained from eighteen normal subjects as controls and from forty-eight diabetics was assessed. In controls, O(2) generation was 6.03±1.31 (mean±SD) n mole per minute per 10(6) cells and in diabetics, 4.33±2.13 which was significantly lower than controls (p<0.001). According to fasting glucose level (FBS), diabetic subjects were classified into three subgroups; well (FBS≦140 mg per 100 ml), fair (140
キーワード
スーパーオキサイド
好中球
殺菌能
糖尿病
ISSN
0030-1558
NCID
AN00032489