Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

異臭魚の発生と石油成分の食物連鎖 第3編 n-パラフィン経口投与時のラット臓器内分布

三宅 与志雄 岡山大学医学部公衆衛生学教室
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In order to study transfer of n-paraffins in crude oil from fish flesh to animals, following experiment were conducted. n-Paraffins (C(10)-C(20)) were administered orally to rat and distribution of n-paraffins in organs were determined by gas chromatography and the following results were obtained. 1) n-Paraffins were detected in all organs tested. 2) Maximam concentrations of n-paraffins in the organs were in the order of liver adipose tissue femoral muscles blood. 3) n-Paraffins in the organs decreased as the lapse of time relatively fast and the order was liver blood femoral muscles adipose tissue. And adipose tissue were thought to be accumulated tissue of n-paraffins. 4) The concentration of C(16) n-paraffin was the highest in all the n-paraffins and it's biological half life was in the order of blood adipose tissue femoral muscles liver.