WALKER CARCINOMA移植RATにおける⊿(4)-CHOLESTENONE-4-C(14)の代謝 第2編 肝の酵素分画による代謝

⊿(4)-Cholestenone-4-C(14) metabolisms were studied with the nuclear, mitochondrial, microsomal and supernatant fraction. Enzymic activity of cholestenone to cholestanone was higher in nuclear and mitochondrial fraction, and the activity was higher about 2-4 times in tumor-bearing rat. This suggests the enzyme block from cholestenone to cholestanone. Inaceton powder, these enzymes were inactivated, and the enzymes were easisted in the fraction precipitated with the concentration of (NH(4))(2)SO(4) at 30g/dl.