1) 1,324 villagers of Yoshikawa Village were inoculated with human placental γ-globulin "Neomasin" and sufficient effect was observed during the period of prevailing infectious hepatitis in this district of Jyobo-gun, Okayama prefecture. 2) These inoculations were effective even as late as 7 days before onset of hepatitis. 3) Effect of these inoculations did not depent upon age as well as sex of patient.