Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.

腦下垂体とトランスアミナーゼ活性 II ACTHの正常及び脳下垂体剔出ラツト脳肝トランスアミナーゼ活性に及ぼす影響

東 漸 岡山大学医学部神経精神医学教室
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The author estimated the effect of ACTH administration on the transaminase activity in the rat brain and liver. The activities determined were aspartate-glutamate (AsGT), alanine-glutamate (AlGT) and γ-aminobutyrate-glutamate (γAGT) transaminases. The AsGT activities in the brain and liver of the normal rat increased by the administration of ACTH. When ACTH was administered to the hypophysectomized rat, the previously increased activities of the AsGT in the brain and liver decreased to the normal values. The ACTH administration was found noneffective on the AlGT and γAGT activities in the brain and liver of the normal and hypophysectomized rat. The author described some discussion about the difference of the effect of ACTH on the activities of the various transaminases.