Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

Parathionの臓器cholinesterase阻害作用

難波 達治 岡山木学医学部平木内科教室
山田 稔 岡山木学医学部平木内科教室
福原 有光 岡山木学医学部平木内科教室
木村 峻士 岡山木学医学部平木内科教室
前田 昭 岡山木学医学部平木内科教室
丹原 茂雄 岡山木学医学部平木内科教室
山本 昭美 岡山木学医学部平木内科教室
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抄録
Rabbits were given parathion subcutaneously and the cholinesterase of tissues ere estimated manometrically. 1. Rabbits was given 100 mg/kg of parathion, and at the time of death in 45 minutes the cholinesterase activity of plasma fell to 15% of normal, erythrocyte 19%, spinal cord 22%, brain 25%, heart 45%, intestine 48%, kidney 49%, liver and muscle 51%, spleen 57%, lung 61% and stomach 87%. 2. Tissue cholinesterase activity of plasma of rabbits subcutaneouslly injected 5 mg/kg of parathion fell to 15% in 12 hours, lung 18%, 12 hs., erythrocyte 23%, 12 hs., kidney 23%, 48 hs., spleen 25%, 6 hs., stomach 33%, 6 hs., spinal cord 33%, 12hs., brain 41%, 6 hs., heart 45%, 6 hs., intestine 49%, 12 hs., liver 57%, 12 hs., and muscle 58%, 6 hs., 3. Discussion were made on these data.
ISSN
0030-1558
NCID
AN00032489