Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

生体におけるパラチオンの運命

難波 達治 岡山大学医学部平木内科教室
谷本 一 岡山大学医学部平木内科教室
木村 基一郎 岡山大学医学部平木内科教室
福原 有光 岡山大学医学部平木内科教室
山田 稔 岡山大学医学部平木内科教室
中沢 彪 岡山大学医学部平木内科教室
城本 鉄蔵 岡山大学医学部平木内科教室
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抄録
Parathion is distributed equally in the poisoned human bodies, as it has been in the case of experimental animals, and disappeared after 24-48 hours. This may be attributed to the splitting of parathion both p-nitrophenol and diethyl (thio) phosphate. The most part of p-nitrophenol is excreted in the urin within 1-2 days and only a part of it prolonged into a week accompaniing no sign of poisoning. It is said that diethyl (thio) phosphate is excreted similary, but poisonus (1/4-1/5 of parathion) for the human bodies and animals. The splitting above mentioned is based on the enzym action, including cholinesterase which is found in the animal sera and organ extracts. The parathion splitting action of serum is inhibited in the case of various kinds of disease.
ISSN
0030-1558
NCID
AN00032489