惡性腫瘍疾患に於けるPhosphataseの研究 第2編 尿中のPhosphataseの生化学的研究

Acid and alkaline phosphatase contents taken from the urine of patients with malignant and non-maignant tumors were determined as described in the previous paper and the following results were obtained: 1) When comparing with phosphatases in the blood serum, alkaline phosphatase activity in the urine was lower than that of acid phosphatase in normal man. But no difference of phosphatase activity was observed between man and woman. 2) Acid and alkaline phosphatase contents in the urine taken from cases with malignant tumors showed a higher value than those with non-malignant tumor. 3) In those with diseases of the bone, the increase of acid phosphatase contents in the urine was greatest when malignant tumor was combined with it. In diseases of urogenital organ and colon phosphatase showed a higher concentration than the usual value, and the former showed a higher value than the latter. 4) In case of carcinomatous peritonititis or ascites from non-malignant tumor, a significant decrease in acid phosphatase content was found. 5) In case of jaundice, a low value of acid phosphatase was observed though the content of alkaline phosphatase showed an increased.