Journal of Okayama Medical Association
Published by Okayama Medical Association

Full-text articles are available 3 years after publication.


常光 洋輔 国立病院機構福山医療センター 外科
稲垣 優 国立病院機構福山医療センター 外科
濱野 亮輔 国立病院機構福山医療センター 外科
西江 学 国立病院機構福山医療センター 外科
徳永 尚之 国立病院機構福山医療センター 外科
大塚 眞哉 国立病院機構福山医療センター 外科
大崎 俊英 国立病院機構福山医療センター 外科
岩垣 博巳 国立病院機構福山医療センター 外科
120_169.pdf 6.25 MB
We report a rare case of a very large nonfunctioning endocrine tumor of the pancreas without malignant histological features. A 63-year-old woman referred for appetite loss and general fatigue was found to have a tumor in the pancreas head. Computed tomography demonstrated a well-defined pancreatic tumor 45mm in diameter with hypervascular staining in the pancreas head. Angiography showed a hypervascular tumor of the pancreas head and a dilatation of the anterior superior and posterior superior pancreaticoduodenal arteries. The preoperative diagnosis was an endocrine tumor of the pancreas, with undeniable malignancy. Pylorus-preserving pancreaticoduodenectomy was performed. The histopathological diagnosis was a benign nonfunctioning endocrine tumor of the pancreas based on immunohistochemical staining for Chromogranin A, Synaptophysin, and NSE, but not for hormones. The tumor revealed a low labeling index (<2.0%) of Ki-67 indicating its benign character. No tumor recurrence has been identified in the 18 months since surgery.
膵内分泌腫瘍(endocrine tumor of the pancreas)
膵島細胞腫瘍(islet cell tumor)