Journal of Okayama Medical Association
Published by Okayama Medical Association

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Full-text articles are available 3 years after publication.

尿路感染症患者分離 Proteus mirabilis の病原性発現因子の解析

室谷 勝久 岡山大学医学部細菌学教室
Thumnail 103_963.pdf 4.17 MB
抄録
Proteus mirabilis has several pathogenic factors such as adherent ability to urinary tract epitherial cells, urease, motility and resistance to urine. The pathogenic activities of clinically isolated P. mirabilis were analyzed. Higher pathogenic strains (No. 25 and No. 30) which had morphologically different pili but had a higher density of pili showed strong adherent activity to bladder epithelial cells of mouse and rat. These strains also showed a clear chemotaxis to urinary tract tissue extracts. These findings indicate that the combination of adherent, chemotaxis and urease activities is essential for causing of tipical kidney infection by P. mirabilis.
キーワード
P. mirabilis
尿路感染
病原因子
走化性
ウレアーゼ
付着性
備考
原著
ISSN
0030-1558
NCID
AN00032489