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ID 42865
フルテキストURL
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タイトル(別表記)
Plasma Proteins of Patients with Gastric Cancer and the Effect of Operation them I. Plasma Protein Concentrations in Patients with Gastric Cancer and the Effect of Operation on them
著者
塩田 弁治郎 岡山大学医学部津田外科教室
抄録
Patients with gastric cancer today coming under the care of surgeon often considerably malnourished. Because of a high incidence of postoperative complications and deaths in these patients, a study was instituted to investigate the state of their plasma proteins. This paper deals with the plasma protein concentrations in patients with gastic cancer, the effect of operation on them and the significance of plasma protein determination in therapy and as a prognostic aid. The concentrations of plasma protein in 43 patients with gastric cancer were pre- and post-operatively measured by copper sulfate specific gravity method, and 10 normal persons and 26 patients with gastroduodenal ulcer were studied as the control. The results obtained were as follows: 1. A significant decrease in the preoperative concentrations of plasma protein was observed in patients with gastric cancer. 2. Whether radical operation could be performed or not, and whether the gastric passageway was patent or not, made no difference in the plasma protein levels of patients with gastric cancer. 3. The determination of plasma protein was of little significance in the differential diagnosis between gastric cancer and gastroduodenal ulcer except in special cases. In the absence of massive hemorrhage or severe obstruction, plasma protein concentrations below 6.5 g/dl had some significance, those below 6.0 g/dl having a important significance. 4. The lowest level of plasma protein concentration in the patients who overcame a partial gastrectomy for gastric cancer was 4.72 g/dl. 5. Following resection of the stomach for gastric cancer, it was in most cases found that a decrease in plasma protein concentration occurred in the patients having the preoperative level abov 6.5 g/dl, whereas an increase occurred in those showing a level lower than 6.5 g/dl before operation. 6. The most pronounced drop in plasma protein concentration occurred about 7 to 12 days after gastric resection for cancer of the stomach. 7. Most of the patients with gastric cancer who underwent merely exploratory laparotomy or gastrojejunostomy because radical operation was impossible to be performed, showed a increased concentration of plasma protein after operation. 8. Death following operation for gastric cancer was found to occur in the patients who had low levels of plasma protein concentration.
発行日
1955-06-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
67巻
6号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1195
終了ページ
1207
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/67/6/67_6_1195/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
5
Eprints Journal Name
joma