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ID 42742
フルテキストURL
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タイトル(別表記)
Studies on the Barbital Concentration in Body and Sleep Part 2. Barbital Concentrations in Blood and Cerebro-Spinal Fliud
著者
更井 啓介 岡山大学医学部神経精神医学教室
抄録
The pathway by which barbital reaches the brain is still unknown. Generally there are two possible pathways through which substances in blood enter into the brain, namely, one, directly through blood vessels and the other, by way of the choriomeningeal plexus. Barbital will possibly enter the brain by the former pathway but it may enter the brain by way of the cerebro-spinal fluid as in the case of P.(32) In order to verify this point, I have measured the barbital concentrations in the lumbar fluid and the ventricle fluid, each obtained at the time of lobotomy and at the pneumo-ventriclography, respectively. From these results, it has been found that barbital immigrated into the cerebro-spinal fluid faster than bromine so that there seems to be a possible pathway to the brain through this fluid. Moreover, in the measurements of the barbital concentration in the ventricle fluid after oral administration has been found higher than that in the lumbar fluid. For this reason, I believe that the choriomeningeal plexus plays the leading rôle in the production of the cerebro-spinal fluid as contended by other investigators.
発行日
1957-12-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
69巻
12号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
3211
終了ページ
3214
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/69/12/69_12_3211/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma