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ID 42550
フルテキストURL
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タイトル(別表記)
Studies on the Metabolism of Mycobacterium tuberculosis II. Comparative studies on the dehydrogenase reactions by intact cell suspensions and cell-free extracts of virulent and avirulent strains
著者
岡 好万 岡山大学医学部徴生物学教室
抄録
By using H37 Rv and H3 7R astrains of human tubercle bacillus, a series of comparative studies have been made on the dehydrogenase reactions by the intact cells possessing the acid-fast natures and by the cell-free extracts without that nature. The results are as follows: 1) In both strains, in the case of cell-free extracts without the addition of substrate, dehydrogenase activity decreases to about 1/2 of that of the intact cells. 2) With the use of hexose as substrates, the dehydrogenase activities of the cell-free extract of H37Rv strain are somewhat higher than those of intact cells, while in the case of H37Ra strain the activities of the cell-free extract are lower than those of intact cells. 3) The activities of the cell-free extracts to pyruvate and lactate are, in both strains, markedly lower than those of intact cells, whereas in the case of H37 Rv strain the malate dehydrogenating activity is greater in the from of cell-free extract than in intact cells. 4) To histidine, the activity of the cell-free extracts of both strains is far greater than that of intact cells.
発行日
1957-05-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
69巻
5号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1239
終了ページ
1246
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/69/5/69_5_1239/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
9
Eprints Journal Name
joma