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ID 19473
Eprint ID
19473
フルテキストURL
Thumnail 71_2283.pdf 2.28 MB
タイトル(別表記)
Clinical and Experimental Studies on the Characteristics of Idiopathic Thrombocytopenic Purpura Part 3. The Influence of the Spleen in the Guiea Pig with Experimental Thrombocytompenia on Megakaryocytes
著者
本多 正憲 岡山大学医学部平木内科
抄録
In an attempt to study the relationship between the megakaryocyte function and the spleen in experimental thrombocytopenia, the author performed the tissue culture of the bone marrow and the spleen of normal guinea pigs and also the bone-barrow tissue culture of normal guine pigs side by side along with the spleen of the guinea pigs injected with anti-platelet serum on the same slide glass, each by a simple culture method; and observed the number and functions of megakaryocytes appearing in the growth area and the wandering velocity of neutrophils. 1. In the case of the bone-marrow tissue of normal guinea pigs cultured side by side with normal spleen on the same slide, megakaryocytes appering in the growth area was somewhat less in number and their functions were also lower than in the case of the bone-marrow tissue cultuse alone. However, there was no significant difference in the wandering velocity of neutrophils. 2. When the spleen of normal guinea pigs given anti-platelet serum was cultured side by side with bone marrow of normal guinea pigs, no significant difference in number of megakaryocytes appearing could be recognized as compared with the case with the normal spleen, but the functions were markedly decreased. The wandering velocity of neutrophils in both of these cultures was Identically the same. From these findings it has been found that in the spleen of the guinea pigs injected with anti-platelet serum there exists a factor which acts directly on megakaryocytes of the normal guinea pigs as to inhibit their platelet production.
発行日
1959-04-15
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
5-1号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
2283
終了ページ
2292
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/5-1/71_5-1_2283/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
31
Eprints Journal Name
joma