ID | 18090 |
Eprint ID | 18090
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フルテキストURL | |
タイトル(別表記) | Immunological Studies on Systemic Lupus Erythematosus Part Ⅱ Experimental Production of Systemic Lupus Erythematosus (SLE)
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著者 |
宮脇 昌
岡山大学医学部大藤内科教室
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抄録 | 1. There were no changes suggestive of SLE in the rabbits that had received hydralazine in daily dossage of 200mg per kilogram body weight for as long as 4 months. 2. Of the rabbits sensitized with egg white and, in addition, administered with hydralazine, many died suddenly after injections of egg white, but a few rabbits showed anemia, probably hemolytic in type. No LE cell phenomenon or antinuclear factor (ANF) was revealed in this group. 3. Slight leucopenia, albuminuria, hypergamma-globulinemia and increased IgG were found in the rabbits injected with rat anti-rabbit cell nuclei serum. Four rabbits showed nephritis, productive in form at necropsy, with deposition of γ-globulin in glomerular capil laries as revealed by the direct FAT. Weak LE cell phenomenon and ANF were positive in one rabbit. 4. It is presumable that, as in human cases, hereditary factor is impcrtant to produce the models of auto-immune diseases in animals.
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発行日 | 1968-04-30
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 80巻
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号 | 3-4号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 399
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終了ページ | 409
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/80/3-4/80_3-4_399/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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