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ID 16625
Eprint ID
16625
フルテキストURL
Thumnail 93_667.pdf 1.47 MB
タイトル(別表記)
CYTOLOGICAL STUDIES ON BRONCHOALVEOLAR LAVAGE FLUID IN BRONCHIAL ASTHMA
著者
竹山 博泰 岡山大学医学部第2内科学教室
抄録
Cytological studies were performed on bronchoalvelar lavage(BAL) fluid in 40 cases with bronchial asthma. The results were as follows. 1) In 13 healthy subjects the cells in BAL fluid comprised 89.6% macrophages, 9.7% lymphocytes, 0.7% neutrophils, 0.4% eosinophils and 0% basophils. 2) In asthmatic cases the cells in BAL fluid comprised 54.4% macrophages, 12.6% lymphocytes, 11.8% neutrophils, 21.2% eosinophils and 0.1% basophils. These cases showed a marked increase in the number of eosinophils and a moderate increase in the neutrophil count as compared with healthy subjects. The increased number of eosinophils in lavage fluid was relatively closely related to positive immediate skin tests, high serum IgE levels and peripheral eosinophilia. As for asthmatic types, this was marked in the atopic type. By contrast, an increased number of neutrophils in the lavage fluid was frequently found in non-atopic or intractable asthmatics showing the frequent complication of peripheral airway disorder in pulmonary function tests. Therefore, it seems that the present study gave much information on the characteristics and the etiology of the intractable asthmatics. 3) Eosinophils in BAL fluid reflected the appearance of eosinophils in the alveolar spaces and eosinophil infiltration into the septa in the histological findings. On the other hand, neutrophils could be observed clearly by the BAL method even when they could not be observed clearly by histological studies. In conclusion, the cytological studies performed on BAL fluid are considered useful in the diagnosis of bronchial asthma, especially for the classification into subtypes of asthma.
キーワード
bronchoalveolar lavage
bronchial asthma
eosinophils
neutrophils
発行日
1981-08-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
93巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
667
終了ページ
683
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/93/7-8/93_7-8_667/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
OAI-PMH Set
岡山大学
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Sort Key
3
Eprints Journal Name
joma