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ID 16623
Eprint ID
16623
フルテキストURL
Thumnail 93_657.pdf 458 KB
タイトル(別表記)
Enzymological studies on rheumatoid arthritis. 2. Relationship between collagenase activity and the clinical course of patients with rheumatoid arthritis
著者
戸田 俊介 岡山大学医学部第三内科教室
抄録
We examined the relationship between collagenase activity and the clinical course of the patients with rheumatoid arthritis (RA). The activity of active and inactive collagenase (treated by 3M-KI) was assayed several times for synovial fluid from twelve RA patients and one patient with osteoarthritis (OA). Rheumatoid factor, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), leukocyte counts and acid-phosphatase activity in the synovial fluid were measured simultaneously. In seven of twelve cases, the change of inactive collagenase activity was parallel by changes in synovial leukocyte counts or acid-phosphatase activity. In five of seven cases, the change in inactive collagenase activity was paralleled by acid-phosphatase activity and leukocyte counts. These findings suggest that collagenase activity is intimately correlated with the grade of local inflammation of RA and that the change of collagenase activity is closely correlated with the clinical course of RA patients.
キーワード
慢性関節リウマチ
コラゲナーゼ活性
発行日
1981-08-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
93巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
657
終了ページ
666
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/93/7-8/93_7-8_657/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma