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ID 16013
Eprint ID
16013
フルテキストURL
Thumnail 99_1189.pdf 438 KB
タイトル(別表記)
Studies on aortic medial smooth muscle cell culture Part 1. The effects of lipid peroxides on cell proliferation in cells derived from aged or diabetic rats
著者
石岡 達司 岡山大学医学部第二内科学教室
抄録
The cultured smooth muscle cell offers several advantages to investigation of cell character. It can be utilized to make studies on aging and atherosclerosis. This work was carried out to investigate the effects of intracellular lipid peroxides and aging on the growth rate of cultured aortic medial smooth muscle cells obtained from normal rats and rats with streptozotosin-induced rats. Cells from young and old rats showed similar growth and contained the same amount of intracellular lipid peroxides. However the rate of growth of cells from diabetic rats was inversely proportional to the period of illness and also to the quantity of lipid peroxides contained in the cells. When normal cells were cultured in an adriamycin-containing medium, their growth rate was inversely proportional to the adriamycin concentration of the medium and also the amount of intracellular lipid peroxides.
キーワード
過酸化脂質
大動脈中膜平滑筋培養
糖尿病
加齢
発行日
1987-10-31
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
99巻
9-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1189
終了ページ
1196
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/99/9-10/99_9-10_1189/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma