start-ver=1.4 cd-journal=joma no-vol=191 cd-vols= no-issue= article-no= start-page=107592 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A novel wearable dosimeter system that can analyze the incident direction of X-rays for medical dosimetry – Improvements to the detector arrangements and analysis algorithm – en-subtitle= kn-subtitle= en-abstract= kn-abstract=When performing real-time dosimetry using an active-type dosimeter during clinical fluoroscopic procedures, angular dependence of dosimeter response should be taken into account. Our research group addressed this issue and proposed a triple-type dosimeter that can determine the incident angle of scattered X-rays. The triple-type detector consists of three active dosimeters. The two side dosimeters have slope filters to enhance the angular dependence and are intentionally tilted. The central dosimeter faces forward. The incident angle of X-rays (θin) is estimated using the signal differences between the central dosimeter and the left and/or right dosimeters. Then, the absolute dose is determined by correcting the angular dependence of the central dosimeter based on the estimated θin. In order to verify the concept of the triple-type dosimeter, we conducted a proof-of-concept experiment using clinical X-ray fluoroscopic equipment. Scattered X-rays were generated by irradiating an elliptical cylindrical water phantom. The response of the triple-type dosimeter was evaluated by rotating it to vary the incident angle of scattered X-rays generated by the water phantom. The proposed dosimetry system could estimate the θin over an angular range of ±80° (with uncertainty of 1.35°), which is 30° wider than the previous version, and successfully determined the absolute doses after correction for the angular dependence of the dosimeter. Although the active-type dosimeter had a systematic uncertainty related to the angular dependence of ±15.2 %, our system succeeded in reducing the systematic uncertainty to ±3.2 %. en-copyright= kn-copyright= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakegamiKazuki en-aut-sei=Takegami en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IshiiRin en-aut-sei=Ishii en-aut-mei=Rin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MitaniMana en-aut-sei=Mitani en-aut-mei=Mana kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=IguchiToshihiro en-aut-sei=Iguchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= affil-num=1 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=3 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=4 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=5 en-affil=Faculty of Health Science, Kobe Tokiwa University kn-affil= affil-num=6 en-affil=Department of Radiological Technology, Yamaguchi University Hospital kn-affil= affil-num=7 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= affil-num=8 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=9 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=10 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=11 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=Wearable active-type dosimeter kn-keyword=Wearable active-type dosimeter en-keyword=X-ray incident direction kn-keyword=X-ray incident direction en-keyword=Occupational dose kn-keyword=Occupational dose en-keyword=Interventional radiology kn-keyword=Interventional radiology END start-ver=1.4 cd-journal=joma no-vol=32 cd-vols= no-issue=2 article-no= start-page=103274 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Optimization of the reconstruction kernel for temporal bone imaging using photon-counting detector CT: A combined physical and visual evaluation en-subtitle= kn-subtitle= en-abstract= kn-abstract=Introduction: Photon-counting detector CT (PCD-CT) offers superior spatial resolution and noise characteristics compared to conventional CT. However, optimal reconstruction parameters for temporal bone imaging, especially kernel selection, remain unclear. This study aimed to identify the optimal reconstruction kernel using both objective physical image quality metrics and subjective expert assessments.
Methods: In phantom experiments, the system performance function (SPF) based on the task-based transfer function (TTF) and noise power spectrum (NPS) was calculated across 11 reconstruction kernels (Hr60–Hr98). Based on the results of the physical evaluation and clinical considerations from clinical practice, a subset of kernels was selected for visual assessment. For clinical images, two diagnostic radiologists evaluated three fine anatomical structures (i.e., stapes footplate, incudomalleolar joint, and cochlea) and overall image quality using both a ranking method and a 5-point Likert scale.
Results: TTF analysis indicated that Hr96 had the highest spatial resolution, while Hr60 showed the lowest noise in the NPS. SPF analysis identified Hr72 as providing the optimal balance between resolution and noise. Visual assessment using four reconstruction kernels (Hr60, Hr72, Hr76, and Hr84) showed that Hr76 consistently received the highest preference for overall image quality and visualization of fine structures. Statistically significant differences were observed among the kernels, with Hr60 consistently rated the lowest (p < 0.05).
Conclusion: The kernel Hr76 was found suitable for middle and inner ear diagnoses using PCD-CT, providing a good balance between spatial resolution and image noise. This finding provides a foundation for standardized reconstruction protocols in high-resolution temporal bone imaging.
Implications for practice: These findings support the use of Hr76 as a standard kernel for high-resolution temporal bone imaging and may contribute to protocol optimization in clinical PCD-CT practice. en-copyright= kn-copyright= en-aut-name=NishiiS. en-aut-sei=Nishii en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AsaharaT. en-aut-sei=Asahara en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MorimitsuY. en-aut-sei=Morimitsu en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KajisakiS. en-aut-sei=Kajisaki en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AkagiN. en-aut-sei=Akagi en-aut-mei=N. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HondaM. en-aut-sei=Honda en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HayashiH. en-aut-sei=Hayashi en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SugayaA. en-aut-sei=Sugaya en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MunetomoK. en-aut-sei=Munetomo en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HigakiF. en-aut-sei=Higaki en-aut-mei=F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=HirakiT. en-aut-sei=Hiraki en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=IguchiT. en-aut-sei=Iguchi en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil=Graduate School of Health Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=3 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=4 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=5 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=6 en-affil=Division of Radiological Technology, Medical Support Department, Okayama University Hospital kn-affil= affil-num=7 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= affil-num=8 en-affil=Department of Otolaryngology, Head & Neck Surgery, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=9 en-affil=Department of Radiology, Medical Development Field, Okayama University kn-affil= affil-num=10 en-affil=Department of Radiology, Medical Development Field, Okayama University kn-affil= affil-num=11 en-affil=Department of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=12 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= en-keyword=Photon-counting CT kn-keyword=Photon-counting CT en-keyword=Temporal bone imaging kn-keyword=Temporal bone imaging en-keyword=Reconstruction kernel kn-keyword=Reconstruction kernel en-keyword=Image quality kn-keyword=Image quality END start-ver=1.4 cd-journal=joma no-vol=239 cd-vols= no-issue= article-no= start-page=113260 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Helical X-ray tube trajectory estimation via image noise analysis for enhanced CT dosimetry en-subtitle= kn-subtitle= en-abstract= kn-abstract=Information on the helical trajectory of the X-ray tube is necessary for accurate dose evaluation during computed tomography (CT). We aimed to propose a methodology for analyzing the trajectory of the X-ray tube. The novelty of this paper is that the incident direction of X-rays is estimated from the standard deviation (SD) distribution. The X-ray incident direction for each slice was analyzed using a distribution function of SD values, in which the analysis regions were placed in the air region. Then, the helical trajectory of the CT scan was estimated by fitting a three-dimensional helical function to the analyzed data. The robustness of our algorithm was verified through phantom studies: the analyzed X-ray incident directions were compared with instrumental log data, in which cylindrical polyoxymethylene resin phantoms and a whole-body phantom were scanned. Chest CT scanning was mimicked, in which the field of view (FOV) was set at the lung region. The procedure for analyzing the X-ray incident direction was applicable to cylindrical phantoms regardless of the phantom size. In contrast, in the case of the whole-body phantom, although it was possible to apply our procedure to the chest and abdomen regions, the shoulder slices were inappropriate to analyze. Therefore, the helical trajectory was determined based on chest and abdominal CT images. The accuracy in X-ray incident direction analysis was evaluated to be 7.5°. In conclusion, we have developed an algorithm to estimate a three-dimensional helical trajectory that can be used for dose measurements and simulations. en-copyright= kn-copyright= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakegamiKazuki en-aut-sei=Takegami en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YamashitaKazuta en-aut-sei=Yamashita en-aut-mei=Kazuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HigashinoKosaku en-aut-sei=Higashino en-aut-mei=Kosaku kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MorimotoShinichi en-aut-sei=Morimoto en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=KonishiTakeshi en-aut-sei=Konishi en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=MakiMotochika en-aut-sei=Maki en-aut-mei=Motochika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=2 en-affil=Department of Radiological Technology, Yamaguchi University Hospital kn-affil= affil-num=3 en-affil=Faculty of Health Sciences, Kobe Tokiwa University kn-affil= affil-num=4 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=6 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=7 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=8 en-affil=Department of Orthopedics, School of Medicine, Tokushima University kn-affil= affil-num=9 en-affil=Shikoku Medical Center for Children and Adults kn-affil= affil-num=10 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=11 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=12 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=13 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=X-ray medical diagnosis kn-keyword=X-ray medical diagnosis en-keyword=Helical CT scan kn-keyword=Helical CT scan en-keyword=CT image kn-keyword=CT image en-keyword=X-ray incident direction kn-keyword=X-ray incident direction en-keyword=Helical trajectory kn-keyword=Helical trajectory en-keyword=Radiation dose measurement kn-keyword=Radiation dose measurement END start-ver=1.4 cd-journal=joma no-vol=238 cd-vols= no-issue= article-no= start-page=113243 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202601 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Bone-enhanced high contrast X-ray images derived from attenuation estimation related to ultra-low energy X-rays – An application of an energy-resolving photon-counting detector (ERPCD) en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose: X-ray diagnosis in medicine is often used for bone diagnosis based on qualitative observation analysis. However, there are often cases where the contrast of bones is reduced because of the existence of soft-tissues, making it difficult to accurately diagnose the bone conditions. Although the algorithm for bone extraction images was proposed using an energy-resolving photon-counting detector (ERPCD), this algorithm can depict “one” bone material (such as hydroxyapatite under the assumption), and it is difficult to adequately depict other components. The purpose of this study is to develop an algorithm for bone-enhanced high-contrast images that can be virtually represented by the attenuation of extremely low-energy X-rays without making any special assumptions.
Methods: High-contrast images were virtually generated based on the attenuation rate of ultra-low energy X-rays. It was determined by fitting the mass attenuation coefficient (μ/ρ) curve to the X-ray attenuation values (μt values) measured at middle (30–40 keV) and high (40–60 keV) energy windows, and extrapolating the μt values to those for the low energy region (E = 5–20 keV). When performing the extrapolation, the effective atomic number (Zeff ) of the object was taken into consideration. The methodology was validated by simulating X-ray projections using a digital human body phantom. The frequency of correspondence between the pixel values in the high-contrast image and the Zeff image was analyzed for each pixel.
Results: We succeeded in creating virtual high-contrast X-ray images that reflect the image contrast of monochromatic X-rays of 5–20 keV. It was confirmed that the pixel values in the high-contrast image corresponding to an Zeff = 7.5 (soft-tissue) were completely separated from those corresponding to an Zeff = 9 (bone). The optimization of the energy related to the high contrast images was performed based on the contrast-to-noise ratio (CNR) analysis. The high contrast image with 10 keV showed a good CNR value.
Conclusions: Based on the analysis of the attenuation information of middle and high-energy X-rays measured by ERPCDs, we succeeded in creating a novel algorithm that can generate a virtual monochromatic image with high contrast. en-copyright= kn-copyright= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HabaTomonobu en-aut-sei=Haba en-aut-mei=Tomonobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KanazawaYuki en-aut-sei=Kanazawa en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YamamotoShuichiro en-aut-sei=Yamamoto en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=2 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=3 en-affil=Faculty of Health Sciences, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=5 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=6 en-affil=Faculty of Health Sciences, Kobe Tokiwa University kn-affil= affil-num=7 en-affil=Faculty of Radiological Technology, School of Medical Science, Fujita Health University kn-affil= affil-num=8 en-affil=Faculty of Life Science, Kumamoto University kn-affil= affil-num=9 en-affil=JOB CORPORATION kn-affil= affil-num=10 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=Medical X-ray diagnosis kn-keyword=Medical X-ray diagnosis en-keyword=Photon-counting detector kn-keyword=Photon-counting detector en-keyword=High contrast image kn-keyword=High contrast image en-keyword=Virtual monochromatic image kn-keyword=Virtual monochromatic image en-keyword=Effective atomic number kn-keyword=Effective atomic number en-keyword=Ultra-low energy image kn-keyword=Ultra-low energy image END start-ver=1.4 cd-journal=joma no-vol=239 cd-vols= no-issue= article-no= start-page=113237 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Counting-loss correction procedure of X-ray imaging detectors with consideration for the effective atomic number of biological objects en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is necessary to correct counting loss caused by the pulse pile-up effect and dead time when using energy-resolving photon-counting detectors (ERPCDs) under “high-counting-rate” conditions in medical and/or industrial settings. We aimed to develop a novel counting-loss correction procedure in which biological objects having effective atomic numbers (Zeff values) of 6.5–13.0 are measured with polychromatic X-rays. To correct for counting loss, such a procedure must theoretically estimate the count value of an ideal X-ray spectrum without counting loss. In this study, we estimated the ideal X-ray spectrum by focusing on the following two points: (1) the X-ray attenuation in an object (Zeff values of 6.5–13.0) and (2) the detector response. Virtual materials having intermediate atomic numbers between 6.5 and 13.0 were generated by using a mixture of polymethylmethacrylate (PMMA, Zeff = 6.5) and aluminum (Al, Zeff = 13.0). We then constructed an algorithm that can perform the counting-loss correction based on the object’s true Zeff value. To demonstrate the applicability of our procedure, we analyzed investigational objects consisting of PMMA and Al using a prototype ERPCD system. A fresh fish sample was also analyzed. The Zeff values agree with the theoretical values within an accuracy of Zeff ±1. In conclusion, we have developed a highly accurate procedure for correcting counting losses for the quantitative X-ray imaging of biological objects. en-copyright= kn-copyright= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KanazawaYuki en-aut-sei=Kanazawa en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KatsumataAkitoshi en-aut-sei=Katsumata en-aut-mei=Akitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YamamotoShuichiro en-aut-sei=Yamamoto en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=2 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=3 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=4 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=5 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=6 en-affil=Faculty of Health Science, Kobe Tokiwa University kn-affil= affil-num=7 en-affil=Faculty of Life Science, Kumamoto University kn-affil= affil-num=8 en-affil=Oral Radiology and Artificial Intelligence, Asahi University kn-affil= affil-num=9 en-affil=JOB CORPORATION kn-affil= affil-num=10 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=Photon-counting detector kn-keyword=Photon-counting detector en-keyword=Pulse pile-up kn-keyword=Pulse pile-up en-keyword=Dead time kn-keyword=Dead time en-keyword=Counting-loss correction kn-keyword=Counting-loss correction en-keyword=Charge-sharing effect kn-keyword=Charge-sharing effect en-keyword=Effective atomic number kn-keyword=Effective atomic number END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯性上顎洞炎に対する内視鏡下副鼻腔手術および歯科治療の治療効果に関する臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TOKUSHIGEYu en-aut-sei=TOKUSHIGE en-aut-mei=Yu kn-aut-name=德重侑 kn-aut-sei=德重 kn-aut-mei=侑 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=矯正歯科治療におけるセルフケアに対する自己効力感測定尺度の開発および信頼性・妥当性の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YAMAJIKana en-aut-sei=YAMAJI en-aut-mei=Kana kn-aut-name=山地加奈 kn-aut-sei=山地 kn-aut-mei=加奈 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=口腔保健行動、健康信念モデル、および絶対的リスク回避度が日本の大学生の定期的な歯科健診受診の意志に及ぼす影響について:横断研究 kn-title=The Impact of Oral Health Behaviors, Health Belief Model, and Absolute Risk Aversion on the Willingness of Japanese University Students to Undergo Regular Dental Check-Ups: A Cross-Sectional Study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SUMITAIchiro en-aut-sei=SUMITA en-aut-mei=Ichiro kn-aut-name=角田伊知郎 kn-aut-sei=角田 kn-aut-mei=伊知郎 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=骨格性I級不正咬合における上下顎両側小臼歯抜去を伴う矯正歯科治療が咽頭部上気道に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KONKOMegumi en-aut-sei=KONKO en-aut-mei=Megumi kn-aut-name=金光恵 kn-aut-sei=金光 kn-aut-mei=恵 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=高齢外来患者における欠損補綴歯科治療法,食品摂取多様性スコアおよび摂取可能食品スコアとの関連 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SAKAMOTOKazuki en-aut-sei=SAKAMOTO en-aut-mei=Kazuki kn-aut-name=坂本和基 kn-aut-sei=坂本 kn-aut-mei=和基 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=1 article-no= start-page=33 end-page=36 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exosome kn-title=エクソソーム en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=EguchiTakanori en-aut-sei=Eguchi en-aut-mei=Takanori kn-aut-name=江口傑徳 kn-aut-sei=江口 kn-aut-mei=傑徳 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Dental Pharmacology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域 歯科薬理学 END start-ver=1.4 cd-journal=joma no-vol=155 cd-vols= no-issue= article-no= start-page=105797 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=202311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ruxolitinib altered IFN-β induced necroptosis of human dental pulp stem cells during osteoblast differentiation en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objective: This study aimed to evaluate the role of ruxolitinib in the interferon beta (IFN-β) mediated osteoblast differentiation using human dental pulp stem cells (hDPSCs).
Design: hDPSCs from five deciduous teeth of healthy patients were stimulated by adding human recombinant IFN-β protein (1 or 2 ng/ml) to the osteogenic differentiation induction medium. Substrate formation was determined using Alizarin Red staining, calcium concentration, and osteoblast marker expression levels. Ruxolitinib was used to inhibit the Janus kinase/signal transducers and activators of transcription (JAK-STAT) pathway. Apoptosis was detected using terminal deoxynucleotidyl nick-end labeling (TUNEL) staining, and necroptosis was detected using propidium iodide staining and phosphorylated mixed lineage kinase domain-like protein (pMLKL) expression.
Results: In the IFN-β-treated group, substrate formation was inhibited by a reduction in alkaline phosphatase (ALP) expression in a concentration-dependent manner. Although the proliferation potency was unchanged between the IFN-β-treated and control groups, the cell number was significantly reduced in the experimental group. TUNEL-positive cell number was not significantly different; however, the protein level of necroptosis markers, interleukin-6 (IL-6) and pMLKL were significantly increased in the substrate formation. Cell number and ALP expression level were improved in the group administered ruxolitinib, a JAK-STAT inhibitor. Additionally, ruxolitinib significantly suppressed IL-6 and pMLKL levels.
Conclusion: Ruxolitinib interfered with the IFN-β-mediated necroptosis and osteogenic differentiation via the JAK-STAT pathway. en-copyright= kn-copyright= en-aut-name=TanakaAtsuko en-aut-sei=Tanaka en-aut-mei=Atsuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HayanoSatoru en-aut-sei=Hayano en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NagataMasayo en-aut-sei=Nagata en-aut-mei=Masayo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KosamiTakahiro en-aut-sei=Kosami en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=WangZiyi en-aut-sei=Wang en-aut-mei=Ziyi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KamiokaHiroshi en-aut-sei=Kamioka en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Orthodontics, Okayama University Hospital kn-affil= affil-num=2 en-affil=Department of Orthodontics, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Type-I interferon kn-keyword=Type-I interferon en-keyword=Janus kinase/signal transducers and activators of transcription pathway kn-keyword=Janus kinase/signal transducers and activators of transcription pathway en-keyword=Osteoblast kn-keyword=Osteoblast en-keyword=Necroptosis kn-keyword=Necroptosis en-keyword=Singleton-Merten Syndrome kn-keyword=Singleton-Merten Syndrome END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=矯正歯科治療におけるボンディング法の決定に必要な因子の探索-単一施設非盲検準ランダム化比較試験- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TANIZAKISaori en-aut-sei=TANIZAKI en-aut-mei=Saori kn-aut-name=谷崎沙織 kn-aut-sei=谷崎 kn-aut-mei=沙織 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=41 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=2022 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Interpretation of the official Japanese translation summary of the “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy” (Updated 2019-2020) kn-title=「MASCC/ISOO 口腔粘膜障害のマネジメントに関する臨床ガイドライン(2019-2020改訂版)」公式日本語訳概要の解釈について en-subtitle= kn-subtitle= en-abstract=Adverse events frequently occur with chemotherapy, radiation therapy involving the oral cavity, and hematopoietic stem cell transplantation in cancer treatment. The Multinational Association of Supportive Care in Cancer and the International Society for Oral Oncology (MASCC/ISOO) have developed a systematic review methodology and published a updated version of the “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy” in 2019-2020. In addition, an official Japanese translation of the summary overview was also published. However, because it is an international guideline, some references are made to unapproved drugs or off-label use in Japan. In addition, some parts of the summary outline do not convey the intent derived from the original text. This paper introduces the contents of the revised guideline and details the contents of the summary overview of the guideline with the above-mentioned problems in mind. kn-abstract=がん治療における化学療法、口腔を照射野に含む放射線療法、および造血幹細胞移植では、有害事象として口腔粘膜障害がしばしば発生する。がん支持療法の国際学会であるMultinational Association of Supportive Care in Cancer および International Society for Oral Oncology (MASCC/ISOO)は、システマティックレビューの手法により、2019年から2020年にかけて、「MASCC/ISOO 口腔粘膜障害のマネジメントに関する臨床ガイドライン」の改訂版を発表した。さらに、総括の概要について、日本語の公式翻訳版も発表された。しかし、国際的なガイドラインであるが故に、日本での非承認薬あるいは適応外使用について言及されている内容が多い。また、総括の概要で、原文に由来する意図が伝わりにくい箇所がある。本稿では、改訂されたガイドラインの内容について紹介するとともに、上述した問題点を念頭に、ガイドラインの総括の概要に記載された内容について詳述した。 en-copyright= kn-copyright= en-aut-name=SOGAYoshihiko en-aut-sei=SOGA en-aut-mei=Yoshihiko kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=1 ORCID= affil-num=1 en-affil=Division of Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院 医療支援歯科治療部 en-keyword=口腔粘膜障害 kn-keyword=口腔粘膜障害 en-keyword=口腔粘膜炎 kn-keyword=口腔粘膜炎 en-keyword=がん治療 kn-keyword=がん治療 en-keyword=ガイドライン kn-keyword=ガイドライン en-keyword=MASCC/ISOO kn-keyword=MASCC/ISOO END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=矯正歯科治療による上顎中切歯の後方移動が上気道の形態におよぼす影響についての研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshidaTomoko en-aut-sei=Ishida en-aut-mei=Tomoko kn-aut-name=石田朋子 kn-aut-sei=石田 kn-aut-mei=朋子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=133 cd-vols= no-issue=3 article-no= start-page=184 end-page=188 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AI research in dentistry and related clinical-study design kn-title=歯学におけるAI研究と研究デザイン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Kimura-OnoAya en-aut-sei=Kimura-Ono en-aut-mei=Aya kn-aut-name=大野彩 kn-aut-sei=大野 kn-aut-mei=彩 aut-affil-num=1 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name=窪木拓男 kn-aut-sei=窪木 kn-aut-mei=拓男 aut-affil-num=2 ORCID= affil-num=1 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil=岡山大学病院 新医療研究開発センター affil-num=2 en-affil=Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学学術研究院医歯薬学域 インプラント再生補綴学 en-keyword=人工知能 kn-keyword=人工知能 en-keyword=歯科 kn-keyword=歯科 en-keyword=臨床研究デザイン kn-keyword=臨床研究デザイン END start-ver=1.4 cd-journal=joma no-vol=133 cd-vols= no-issue=3 article-no= start-page=181 end-page=183 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AI in dentistry and clues for starting AI research kn-title=歯学領域におけるAIとAI研究開始時の障壁 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KodamaNaoki en-aut-sei=Kodama en-aut-mei=Naoki kn-aut-name=兒玉直紀 kn-aut-sei=兒玉 kn-aut-mei=直紀 aut-affil-num=1 ORCID= en-aut-name=SugimotoHikaru en-aut-sei=Sugimoto en-aut-mei=Hikaru kn-aut-name=杉本皓 kn-aut-sei=杉本 kn-aut-mei=皓 aut-affil-num=2 ORCID= en-aut-name=MinagiShogo en-aut-sei=Minagi en-aut-mei=Shogo kn-aut-name=皆木省吾 kn-aut-sei=皆木 kn-aut-mei=省吾 aut-affil-num=3 ORCID= affil-num=1 en-affil=Department of Prosthodontics, Division of Dentistry, Okayama University Hospital kn-affil=岡山大学病院 歯科(補綴歯科部門) affil-num=2 en-affil=Department of Occlusal and Oral Functional Rehabilitation, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学学術研究院医歯薬学域 咬合・有床義歯補綴学 affil-num=3 en-affil=Department of Occlusal and Oral Functional Rehabilitation, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学学術研究院医歯薬学域 咬合・有床義歯補綴学 en-keyword=人工知能 kn-keyword=人工知能 en-keyword=歯科 kn-keyword=歯科 en-keyword=咀嚼 kn-keyword=咀嚼 END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue= article-no= start-page=11 end-page=27 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211224 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Perceived Stress of Students under the COVID-19 Crisis. kn-title=新型コロナウイルス感染症状況下における大学生の主観的ストレス en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SumiokaKyoko en-aut-sei=Sumioka en-aut-mei=Kyoko kn-aut-name=住岡恭子 kn-aut-sei=住岡 kn-aut-mei=恭子 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=和泉里佳 kn-aut-sei=和泉 kn-aut-mei=里佳 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学学術研究院社会文化科学学域 affil-num=2 en-affil= kn-affil=IGL医療福祉専門学校歯科衛生学科 END start-ver=1.4 cd-journal=joma no-vol=2021 cd-vols= no-issue= article-no= start-page=1 end-page=11 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=2021929 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Investigation of the molecular causes underlying physical abnormalities in Diamond‐Blackfan anemia patients with RPL5 haploinsufficiency en-subtitle= kn-subtitle= en-abstract= kn-abstract=Diamond-Blackfan anemia (DBA) is a genetic disorder caused by mutations in genes encoding ribosomal proteins and characterized by erythroid aplasia and various physical abnormalities. Although accumulating evidence suggests that defective ribosome biogenesis leads to p53-mediated apoptosis in erythroid progenitor cells, little is known regarding the underlying causes of the physical abnormalities. In this study, we established induced pluripotent stem cells from a DBA patient with RPL5 haploinsufficiency. These cells retained the ability to differentiate into osteoblasts and chondrocytes. However, RPL5 haploinsufficiency impaired the production of mucins and increased apoptosis in differentiated chondrocytes. Increased expression of the pro-apoptotic genes BAX and CASP9 further indicated that RPL5 haploinsufficiency triggered p53-mediated apoptosis in chondrocytes. MDM2, the primary negative regulator of p53, plays a crucial role in erythroid aplasia in DBA patient. We found the phosphorylation level of MDM2 was significantly decreased in RPL5 haploinsufficient chondrocytes. In stark contrast, we found no evidence that RPL5 haploinsufficiency impaired osteogenesis. Collectively, our data support a model in which RPL5 haploinsufficiency specifically induces p53-mediated apoptosis in chondrocytes through MDM2 inhibition, which leads to physical abnormalities in DBA patients. en-copyright= kn-copyright= en-aut-name=FukuiYuko en-aut-sei=Fukui en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HayanoSatoru en-aut-sei=Hayano en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawanabeNoriaki en-aut-sei=Kawanabe en-aut-mei=Noriaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WangZiyi en-aut-sei=Wang en-aut-mei=Ziyi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShimadaAkira en-aut-sei=Shimada en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SaitoMegumu K. en-aut-sei=Saito en-aut-mei=Megumu K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AsakaIsao en-aut-sei=Asaka en-aut-mei=Isao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KamiokaHiroshi en-aut-sei=Kamioka en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=2 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=3 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=4 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=5 en-affil=Department of Pediatric Hematology/Oncology Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Clinical Application, Center for iPS Cell Research and Application Kyoto University kn-affil= affil-num=7 en-affil=Department of Fundamental Cell Technology, Center for iPS Cell Research and Application Kyoto University kn-affil= affil-num=8 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= en-keyword=iPS cell kn-keyword=iPS cell en-keyword=RPL5 kn-keyword=RPL5 en-keyword=cleft lip and palate kn-keyword=cleft lip and palate en-keyword=chondrocyte kn-keyword=chondrocyte en-keyword=Diamond-Blackfan Anemia kn-keyword=Diamond-Blackfan Anemia END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=8 article-no= start-page=1876 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210409 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Assessment of Demineralization Inhibition Effects of Dentin Desensitizers Using Swept-Source Optical Coherence Tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=The purpose of this study was to evaluate the mechanism of action and the inhibiting effects of two types of desensitizers against dentin demineralization using pre-demineralized hypersensitivity tooth model in vitro. In this study, we confirmed that a hypersensitivity tooth model from our preliminary experiment could be prepared by immersing dentin discs in an acetic acid-based solution with pH 5.0 for three days. Dentin discs with three days of demineralization were prepared and applied by one of the desensitizers containing calcium fluoro-alumino-silicate glass (Nanoseal, NS) or fluoro-zinc-silicate glass (Caredyne Shield, CS), followed by an additional three days of demineralization. Dentin discs for three days of demineralization (de3) and six days of demineralization (de6) without the desensitizers were also prepared. The dentin discs after the experimental protocol were scanned using swept-source optical coherence tomography (SS-OCT) to image the cross-sectional (2D) view of the samples and evaluate the SS-OCT signal. The signal intensity profiles of SS-OCT from the region of interest of 300, 500, and 700 mu m in depth were obtained to calculate the integrated signal intensity and signal attenuation coefficient. The morphological differences and remaining chemical elements of the dentin discs were also analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy. SS-OCT images of CS and NS groups showed no obvious differences between the groups. However, SS-OCT signal profiles for both the CS and NS groups showed smaller attenuation coefficients and larger integrated signal intensities than those of the de6 group. Reactional deposits of the desensitizers even after the additional three days of demineralization were observed on the dentin surface in NS group, whereas remnants containing Zn were detected within the dentinal tubules in CS group. Consequently, both CS and NS groups showed inhibition effects against the additional three days of demineralization in this study. Our findings demonstrate that SS-OCT signal analysis can be used to monitor the dentin demineralization and inhibition effects of desensitizers against dentin demineralization in vitro. en-copyright= kn-copyright= en-aut-name=MatsuzakiKumiko en-aut-sei=Matsuzaki en-aut-mei=Kumiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ShinnoYasuo en-aut-sei=Shinno en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OnoSerina en-aut-sei=Ono en-aut-mei=Serina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamajiKozo en-aut-sei=Yamaji en-aut-mei=Kozo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OharaNaoko en-aut-sei=Ohara en-aut-mei=Naoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Biomimetics Biomaterials Biophotonics Biomechanics & Technology Laboratory, Department of Restorative Dentistry, University of Washington kn-affil= affil-num=8 en-affil=Center of Advanced Medicine for Dental and Oral Diseases, Department for Advanced Dental Research, National Center for Geriatrics and Ger Ontology kn-affil= affil-num=9 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=10 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=dentin desensitizer kn-keyword=dentin desensitizer en-keyword=dentin demineralization kn-keyword=dentin demineralization END start-ver=1.4 cd-journal=joma no-vol=56 cd-vols= no-issue=1 article-no= start-page=109 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202011 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of dental caries, tooth crack, and age-related changes in tooth structure using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) is an imaging technique that can visualize the internal biological structure without X-ray exposure. Swept-source OCT (SS-OCT) is one of the latest version of OCT, wherein the light source is a tunable laser that sweeps near-infrared wavelength light to achieve real-time imaging. The imaging depth of OCT is highly influenced by the translucency of the medium. The medium that does not transmit light and the deeper structure beyond the range of light penetration depth are not relevant for OCT imaging. In OCT, sound enamel is almost transparent at the OCT wavelength range, and enamel and dentin can be distinguished from each other as the dentin-enamel junction (DEJ) appears as a dark border. Demineralized enamel and dentin are imaged as bright zones because of the formation of numerous micro-porosities where the backscatter of OCT signal is increased. In cavitated caries at interproximal or occlusal hidden zone, the upper margin of the cavity reflects the signal showing a distinct bright border in the SS-OCT image. SS-OCT is capable of determining crack penetration depth even when the cracks extended beyond the DEJ. SS-OCT has a high degree of sensitivity and specificity for the detection of dental caries and tooth cracks. SS-OCT is also capable of detecting non-carious cervical lesions and occlusal tooth wear in cross-sectional views to estimate the amount of tooth structure loss. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= en-keyword=Optical coherence tomography kn-keyword=Optical coherence tomography en-keyword=Diagnosis kn-keyword=Diagnosis en-keyword=Caries kn-keyword=Caries en-keyword=Tooth crack kn-keyword=Tooth crack en-keyword=NCCL kn-keyword=NCCL en-keyword=Tooth wear kn-keyword=Tooth wear en-keyword=Age-related changes kn-keyword=Age-related changes END start-ver=1.4 cd-journal=joma no-vol=56 cd-vols= no-issue=1 article-no= start-page=109 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of dental caries, tooth crack, and age-related changes in tooth structure using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) is an imaging technique that can visualize the internal biological structure without X-ray exposure. Swept-source OCT (SS-OCT) is one of the latest version of OCT, wherein the light source is a tunable laser that sweeps near-infrared wavelength light to achieve real-time imaging. The imaging depth of OCT is highly influenced by the translucency of the medium. The medium that does not transmit light and the deeper structure beyond the range of light penetration depth are not relevant for OCT imaging. In OCT, sound enamel is almost transparent at the OCT wavelength range, and enamel and dentin can be distinguished from each other as the dentin–enamel junction (DEJ) appears as a dark border. Demineralized enamel and dentin are imaged as bright zones because of the formation of numerous micro-porosities where the backscatter of OCT signal is increased. In cavitated caries at interproximal or occlusal hidden zone, the upper margin of the cavity reflects the signal showing a distinct bright border in the SS-OCT image. SS-OCT is capable of determining crack penetration depth even when the cracks extended beyond the DEJ. SS-OCT has a high degree of sensitivity and specificity for the detection of dental caries and tooth cracks. SS-OCT is also capable of detecting non-carious cervical lesions and occlusal tooth wear in cross-sectional views to estimate the amount of tooth structure loss. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= en-keyword=Optical coherence tomography kn-keyword=Optical coherence tomography en-keyword=Diagnosis kn-keyword=Diagnosis en-keyword=Caries kn-keyword=Caries en-keyword=Tooth crack kn-keyword=Tooth crack en-keyword=NCCL kn-keyword=NCCL en-keyword=Tooth wear kn-keyword=Tooth wear en-keyword=Age-related changes kn-keyword=Age-related changes END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue=21 article-no= start-page=6016 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Diagnosis of Occlusal Tooth Wear Using 3D Imaging of Optical Coherence Tomography Ex Vivo en-subtitle= kn-subtitle= en-abstract= kn-abstract=The aim of this study was to assess the utility of 3D imaging of optical coherence tomography (OCT) for the diagnosis of occlusal tooth wear ex vivo. Sixty-three extracted human molars with or without visible tooth wear were collected to take digital intraoral radiography and 3D OCT images. The degree of tooth wear was evaluated by 12 examiners and scored using 4-rank scale: 1-slight enamel wear; 2-distinct enamel wear; 3-tooth wear with slight dentin exposure; 4-tooth wear with distinct involvement of dentin. The degree of tooth wear was validated by the histological view of confocal laser scanning microscopy (CLSM). The sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic analysis were calculated. Diagnostic accuracy was compared with the agreement with CLSM observation using weighted kappa. The results were statistically analyzed at a significance level of alpha = 0.05. Three-dimensional OCT showed significantly higher sensitivity (p < 0.05) for all the diagnostic thresholds of enamel wear and dentin exposure than digital radiography (0.82, 0.85, and 0.79 vs. 0.56, 0.52, and 0.57, respectively). Three-dimensional OCT showed higher AUC and kappa coefficients than digital radiography (p < 0.05), where mean AUC and Kappa values were 0.95 and 0.76 for OCT and 0.92 and 0.47 for radiography, respectively. No significant difference of specificity was observed (p > 0.05). Three-dimensional OCT could visualize and estimate the degree of tooth wear and detect the dentin exposure at the tooth wear surface accurately and reproducibly. Consequently, a new guideline for tooth wear assessment can be proposed using OCT. en-copyright= kn-copyright= en-aut-name=KashiwaMisa en-aut-sei=Kashiwa en-aut-mei=Misa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Center of Advanced Medicine for Dental and Oral Diseases, Department for Advanced Dental Research, National Center for Geriatrics and Gerontology kn-affil= affil-num=6 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=occlusal tooth wear kn-keyword=occlusal tooth wear en-keyword=erosive tooth wear kn-keyword=erosive tooth wear en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=3D imaging kn-keyword=3D imaging en-keyword=enamel thickness kn-keyword=enamel thickness en-keyword=dentin exposure kn-keyword=dentin exposure en-keyword=demineralization kn-keyword=demineralization END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=1 article-no= start-page=15754 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=3D imaging of proximal caries in posterior teeth using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) can create cross-sectional images of tooth without X-ray exposure. This study aimed to investigate the diagnostic accuracy of 3D imaging of OCT for proximal caries in posterior teeth. Thirty-six human molar teeth with 51 proximal surfaces visibly 6 intact, 16 slightly demineralized, and 29 distinct carious changes were mounted to take digital radiographs and 3D OCT images. The sensitivity, specificity and area under the receiver operating characteristic curve (AUC) for the diagnosis of enamel caries and dentin caries were calculated to quantify the diagnostic ability of 3D OCT in comparison with digital radiography. Diagnostic accuracy was evaluated by the agreement with histology using weighted Kappa. OCT showed significantly higher sensitivity, AUC and Kappa values than radiography. OCT can be a safer option for the diagnosis of proximal caries in posterior teeth that can be applied to the patients without X-ray exposure. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=BurrowMichael F. en-aut-sei=Burrow en-aut-mei=Michael F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ArakiKazuyuki en-aut-sei=Araki en-aut-mei=Kazuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ZhouYuan en-aut-sei=Zhou en-aut-mei=Yuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HosakaKeiichi en-aut-sei=Hosaka en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MiyazakiTakashi en-aut-sei=Miyazaki en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital kn-affil= affil-num=3 en-affil=Department of Oral Diagnostic Sciences, Division of Radiology, Showa University School of Dentistry kn-affil= affil-num=4 en-affil=Department of Preventive Dentistry, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine kn-affil= affil-num=5 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences kn-affil= affil-num=6 en-affil=Department of Restorative Dentistry, University of Washington School of Dentistry kn-affil= affil-num=7 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Conservative Dentistry, Division of Biomaterials and Engineering, Showa University School of Dentistry kn-affil= affil-num=9 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= affil-num=10 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=Dental caries kn-keyword=Dental caries en-keyword=Dental lasers kn-keyword=Dental lasers en-keyword=Laboratory techniques and procedures kn-keyword=Laboratory techniques and procedures END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue=6 article-no= start-page=1659 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200317 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Diagnosis of Occlusal Caries with Dynamic Slicing of 3D Optical Coherence Tomography Images en-subtitle= kn-subtitle= en-abstract= kn-abstract=Detecting the extent of occlusal caries is a clinically important but challenging task required for treatment decision making. The aim of this study was to assess the diagnostic power of 3D swept-source optical coherence tomography (OCT) for evaluation of occlusal caries in comparison with X-ray radiography. Extracted human molars not exhibiting American Dental Association (ADA) criteria advanced caries were mounted in a silicone block and digital dental radiographs were captured from the buccal side. Subsequently, occlusal surfaces were scanned with a prototype Yoshida Dental OCT. Thirteen examiners evaluated the presence and extent of caries on radiographs and dynamically sliced 3D OCT video images, using a 4 level scale-0: intact; 1: enamel demineralization without cavitation; 2: enamel caries with cavitation; 3: dentin caries with or without cavitation. Sensitivity, specificity and area under operating characteristic curves (Az) were statistically analyzed (alpha = 0.05). Reliability analysis showed an excellent agreement among the 13 examiners for both methods. The OCT presented a significantly higher sensitivity and Az value for the detection of caries compared to radiographs (p < 0.05). Radiography showed especially low sensitivity for dentin caries (0-2 versus 3). Dynamic slicing of 3D OCT volumes is a powerful adjunct tool to visual inspection to diagnose the dentin occlusal caries in vitro. en-copyright= kn-copyright= en-aut-name=LuongMinh N. en-aut-sei=Luong en-aut-mei=Minh N. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ArakiKazuyuki en-aut-sei=Araki en-aut-mei=Kazuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Restorative Dentistry, University of Washington kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Division of Radiology, Department of Oral Diagnostic Sciences, Showa University School of Dentistry kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=6 en-affil=Department of Restorative Dentistry, University of Washington kn-affil= en-keyword=dentin kn-keyword=dentin en-keyword=enamel kn-keyword=enamel en-keyword=optical coherence tomography kn-keyword=optical coherence tomography en-keyword=radiograph kn-keyword=radiograph en-keyword=receiver operating characteristic (ROC) analysis kn-keyword=receiver operating characteristic (ROC) analysis en-keyword=hidden caries kn-keyword=hidden caries en-keyword=dentino-enamel junction DEJ kn-keyword=dentino-enamel junction DEJ END start-ver=1.4 cd-journal=joma no-vol=38 cd-vols= no-issue=385 article-no= start-page=798 end-page=805 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Effect of Flowable Composite Lining and Dentin Location on Microtensile Bond Strength and Internal Fracture Formation en-subtitle= kn-subtitle= en-abstract= kn-abstract=The objective of this study was to determine the effect of flowable composite lining and dentin location on internal dentin fracture formation in the microtensile bond strength (MTBS) test using swept-source optical coherence tomography (SS-OCT). MTBS test beams (1.0×1.0 mm) were prepared from human superficial and deep dentin, which was bonded with a self-etch adhesive (Clearfil SE Bond) and hybrid composite resin (Clearfil AP-X), with or without flowable lining (Clearfil Majesty ES-Flow). We tested 4 groups according to placement technique (with vs. without flowable liner) and dentin (superficial vs. deep) locations. Cross-sectional 2D images of the bonded interface were obtained before and after the MTBS test. Internal dentin fracture after MTBT was observed as a bright zone in SS-OCT. Flowable lining significantly reduced internal fracture formation in dentin (p<0.05). Dentin location significantly influenced MTBS (p<0.05), and this was reduced by flowable lining usage. en-copyright= kn-copyright= en-aut-name=KominamiNao en-aut-sei=Kominami en-aut-mei=Nao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HosakaKeiichi en-aut-sei=Hosaka en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=Minh Nguyet Luong en-aut-sei=Minh Nguyet Luong en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University. kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Restorative Dentistry and Endodontics, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City kn-affil= affil-num=5 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University. kn-affil= affil-num=6 en-affil=Biomimetics Biomaterials Biophotonics & Technology Laboratory, Department of Restorative Dentistry, University of Washington School of Dentistry kn-affil= affil-num=7 en-affil=National Center for Geriatrics and Gerontology, Department of Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Disease kn-affil= affil-num=8 en-affil= kn-affil= en-keyword=Dentin kn-keyword=Dentin en-keyword=Internal fracture kn-keyword=Internal fracture en-keyword=Microtensile bond strength test kn-keyword=Microtensile bond strength test en-keyword= SS-OCT kn-keyword= SS-OCT END start-ver=1.4 cd-journal=joma no-vol=38 cd-vols= no-issue=5 article-no= start-page=779 end-page=789 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cavity Adaptation of Composite Restorations Prepared at Crown and Root: Optical Assessment Using SS-OCT en-subtitle= kn-subtitle= en-abstract= kn-abstract= Evaluation of gap formation at the interfaces of a two-step self-etching adhesive with/without pre-etching was performed using sweptsource optical coherence tomography (SS-OCT). Round cavities were prepared in bovine incisors at the middle (MC) and cervical (CC) thirds of the crown and the cervical third of the root (CR). Clearfil SE bond was directly applied to one group (SE) and another (PA) was pretreated with K-etchant gel. Following restoration by flowable composite resin, the teeth were thermally challenged and stored for 2 months. Interfacial gaps observed in the cross-sectional OCT images were analyzed and the bottom cavities exhibited increased gaps compared to the margin and dentin-enamel junction (DEJ). The CR site had a larger gap than at MC and CC in the SE group. DEJ separation at the MC was significantly smaller than that at CC in both groups. Therefore, gap formation depends on the cavity region, location, and bonding protocol. en-copyright= kn-copyright= en-aut-name=Rima Zakzuk Alshahni en-aut-sei=Rima Zakzuk Alshahni en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ZhouYuan en-aut-sei=Zhou en-aut-mei=Yuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Restorative Dentistry, University of Washington, School of Dentistry kn-affil= affil-num=6 en-affil=Division of Oral and Dental Surgery, Department of Advanced Medicine, National Center for Geriatrics and Gerontology, National Hospital for Geriatric Medicine kn-affil= affil-num=7 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=Bottom kn-keyword=Bottom en-keyword=Dentin-enamel junction kn-keyword=Dentin-enamel junction en-keyword=Gap kn-keyword=Gap en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=Self-etch adhesive kn-keyword=Self-etch adhesive END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科関連行動とIgG抗体価で示す歯周病原細菌の感染度との関連の横断研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TsuboiAyaka en-aut-sei=Tsuboi en-aut-mei=Ayaka kn-aut-name=坪井綾香 kn-aut-sei=坪井 kn-aut-mei=綾香 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=医療面接におけるコミュニケーションおよび研修歯科医の共感性と模擬患者評価との関係 kn-title=Relationship of trainee dentists’ self-reported empathy and communication behaviors with simulated patients’ assessment in medical interviews en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeSho en-aut-sei=Watanabe en-aut-mei=Sho kn-aut-name=渡邉翔 kn-aut-sei=渡邉 kn-aut-mei=翔 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=76 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120820 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Perioperative Management Training Program on the Awareness of Team Medicine among Trainee Dentists kn-title=歯科医師臨床研修におけるチーム医療研修プログラム : 研修歯科医の関心および理解に与えた効果の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= 質が高く、安心・安全な医療を実現していくために、チーム医療の促進は重要な課題であり、チーム医療を担う医療人の育成が必要とされている。岡山大学病院歯科医師臨床研修では、平成23年度から周術期管理センターを研修の場とする「チーム医療研修プログラム」を開始した。本報告では、研修歯科医のプログラムに対する関心とチーム医療に関する理解に与えた効果をアンケート調査によって検討することを目的とした。対象は平成23年度本学病院研修歯科医44名とし、医師、看護師、薬剤師、理学療法士、管理栄養士など多職種によって行われる周術期管理チーム医療を体験させた。受講前には本プログラムに対する期待度を、受講後には満足度、有意義度について質問し、研修歯科医のプログラムに対する関心度を評価した。また、プログラム受講前後に周術期チーム医療に関する用語や職種について質問し、チーム医療に関する理解度を評価した。90.9%の研修歯科医がプログラムに対して期待し、受講後は88.6%が満足だった、84.1%が有意義だったと回答した。さらに、周術期管理に関する用語について主観的理解度が向上し、チーム医療にかかわる職種についての理解が深まった。歯科医師臨床研修におけるチーム医療教育の方法として、周術期管理チーム医療の現場に実際に関与させるプログラムは、研修歯科医の関心が高く、研修歯科医の周術期管理チーム医療に対する理解を深めることが示唆された。 en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name=山中玲子 kn-aut-sei=山中 kn-aut-mei=玲子 aut-affil-num=1 ORCID= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=2 ORCID= en-aut-name=YoshitomiAiko en-aut-sei=Yoshitomi en-aut-mei=Aiko kn-aut-name=吉冨愛子 kn-aut-sei=吉冨 kn-aut-mei=愛子 aut-affil-num=3 ORCID= en-aut-name=ShiraiHajime en-aut-sei=Shirai en-aut-mei=Hajime kn-aut-name=白井肇 kn-aut-sei=白井 kn-aut-mei=肇 aut-affil-num=4 ORCID= en-aut-name=SuzukiKoji en-aut-sei=Suzuki en-aut-mei=Koji kn-aut-name=鈴木康司 kn-aut-sei=鈴木 kn-aut-mei=康司 aut-affil-num=5 ORCID= en-aut-name=KonoTakayuki en-aut-sei=Kono en-aut-mei=Takayuki kn-aut-name=河野隆幸 kn-aut-sei=河野 kn-aut-mei=隆幸 aut-affil-num=6 ORCID= en-aut-name=ToriiYasuhiro en-aut-sei=Torii en-aut-mei=Yasuhiro kn-aut-name=鳥井康弘 kn-aut-sei=鳥井 kn-aut-mei=康弘 aut-affil-num=7 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=森田学 kn-aut-sei=森田 kn-aut-mei=学 aut-affil-num=8 ORCID= affil-num=1 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院医療支援歯科治療部 affil-num=2 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院医療支援歯科治療部 affil-num=3 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院医療支援歯科治療部 affil-num=4 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院総合歯科 affil-num=5 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院総合歯科 affil-num=6 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院総合歯科 affil-num=7 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院総合歯科 affil-num=8 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=岡山大学病院医療支援歯科治療部 en-keyword=研修歯科医 kn-keyword=研修歯科医 en-keyword=歯科医師臨床研修 kn-keyword=歯科医師臨床研修 en-keyword=チーム医療 kn-keyword=チーム医療 en-keyword=周術期管理 kn-keyword=周術期管理 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=前歯部開咬患者に対して行われている歯科矯正用アンカースクリューを用いた治療と外科的矯正治療の顎運動,咀嚼運動の機能評価 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=FujisawaAtsuro en-aut-sei=Fujisawa en-aut-mei=Atsuro kn-aut-name=藤澤厚郎 kn-aut-sei=藤澤 kn-aut-mei=厚郎 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=歯科保健の知識およびその情報源と歯科保健行動との関連についての横断研究 kn-title=Associations between dental knowledge, source of dental knowledge and oral health behavior in Japanese university students: A cross-sectional study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TaniguchiAyano en-aut-sei=Taniguchi en-aut-mei=Ayano kn-aut-name=谷口綾乃 kn-aut-sei=谷口 kn-aut-mei=綾乃 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Control of contamination in dental unit water lines applying low-concentrated ozonized water : Effectiveness and Safety kn-title=低濃度オゾン水を応用した歯科用ユニット給水管路内汚染の制御 : 有効性と安全性の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OkuboKeisuke en-aut-sei=Okubo en-aut-mei=Keisuke kn-aut-name=大久保圭祐 kn-aut-sei=大久保 kn-aut-mei=圭祐 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=急性期脳卒中患者に対する歯科介入による口腔感染と経口栄養摂取の管理効果に関する後向き研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsunagaKazuyuki en-aut-sei=Matsunaga en-aut-mei=Kazuyuki kn-aut-name=松永一幸 kn-aut-sei=松永 kn-aut-mei=一幸 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=3 article-no= start-page=191 end-page=196 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Our experience with the significance of collaborative medical and dental surgeries at the Head and Neck Cancer Center, Okayama University Hospital kn-title=岡山大学病院頭頸部がんセンターにおける医科歯科合同手術の現状解析とその意義 en-subtitle= kn-subtitle= en-abstract= kn-abstract=  We have been collaborating with head and neck surgeons, plastic surgeons and oral surgeons in surgeries for many patients with head and neck carcinomas( especially oral carcinomas) since 2006( fiscal year 2005). The Head and Neck Cancer Center was established at Okayama University Hospital in 2012.  This Center was the first of its kind at a national university hospital in Japan.  At the Center, 174 operations on head and neck carcinomas and 96 reconstructive operations were performed in 2014( fiscal year).  Medical and dental collaborative operations have been increasing almost every year since the 2005 fiscal year. There were 45 collaborative operations in the 2014 fiscal year, which included 30 cases of bone or metal plate reconstruction or plate reinforcement of the jaws.  There were 76 medical and dental collaborative operations in the 7 years before the establishment of the Center, with a mean of 10.9 operations per year. Since the establishment of the Center, there have been 112 cases over 3 years with a mean of 37.3 operations per year. The number of surgeries has been markedly increased by the establishment of the Head and Neck Cancer Center. en-copyright= kn-copyright= en-aut-name=MizukawaNobuyoshi en-aut-sei=Mizukawa en-aut-mei=Nobuyoshi kn-aut-name=水川展吉 kn-aut-sei=水川 kn-aut-mei=展吉 aut-affil-num=1 ORCID= en-aut-name=OnodaTomoo en-aut-sei=Onoda en-aut-mei=Tomoo kn-aut-name=小野田友男 kn-aut-sei=小野田 kn-aut-mei=友男 aut-affil-num=2 ORCID= en-aut-name=MatsumotoHiroshi en-aut-sei=Matsumoto en-aut-mei=Hiroshi kn-aut-name=松本洋 kn-aut-sei=松本 kn-aut-mei=洋 aut-affil-num=3 ORCID= en-aut-name=TakedaSeiko en-aut-sei=Takeda en-aut-mei=Seiko kn-aut-name=武田斉子 kn-aut-sei=武田 kn-aut-mei=斉子 aut-affil-num=4 ORCID= en-aut-name=NodaYouhei en-aut-sei=Noda en-aut-mei=Youhei kn-aut-name=野田洋平 kn-aut-sei=野田 kn-aut-mei=洋平 aut-affil-num=5 ORCID= en-aut-name=OnodaSatoshi en-aut-sei=Onoda en-aut-mei=Satoshi kn-aut-name=小野田聡 kn-aut-sei=小野田 kn-aut-mei=聡 aut-affil-num=6 ORCID= en-aut-name=FukushimaMai en-aut-sei=Fukushima en-aut-mei=Mai kn-aut-name=福島麻衣 kn-aut-sei=福島 kn-aut-mei=麻衣 aut-affil-num=7 ORCID= en-aut-name=TsumuraMunechika en-aut-sei=Tsumura en-aut-mei=Munechika kn-aut-name=津村宗近 kn-aut-sei=津村 kn-aut-mei=宗近 aut-affil-num=8 ORCID= en-aut-name=TakeuchiTetsuo en-aut-sei=Takeuchi en-aut-mei=Tetsuo kn-aut-name=竹内哲男 kn-aut-sei=竹内 kn-aut-mei=哲男 aut-affil-num=9 ORCID= en-aut-name=SugiyamaNarushi en-aut-sei=Sugiyama en-aut-mei=Narushi kn-aut-name=杉山成史 kn-aut-sei=杉山 kn-aut-mei=成史 aut-affil-num=10 ORCID= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=木股敬裕 kn-aut-sei=木股 kn-aut-mei=敬裕 aut-affil-num=11 ORCID= affil-num=1 en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター, 顎口腔再建外科 affil-num=2 en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,耳鼻咽喉・頭頸部外科 affil-num=3 en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,形成外科 affil-num=4 en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,顎口腔再建外科 affil-num=5 en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,耳鼻咽喉・頭頸部外科 affil-num=6 en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,形成外科 affil-num=7 en-affil=Departments of Oral and Maxillofacial Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,顎口腔再建外科 affil-num=8 en-affil=Departments of Otorhinolaryngology, Head and Neck Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,耳鼻咽喉・頭頸部外科 affil-num=9 en-affil=Departments of Dental Laboratory, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,歯科技工室 affil-num=10 en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,形成外科 affil-num=11 en-affil=Departments of Plastic and Reconstructive Surgery, Head and Neck Cancer Center, Okayama University Hospital kn-affil=岡山大学病院 頭頸部がんセンター,形成外科 en-keyword=頭頸部がん(head and neck carcinoma) kn-keyword=頭頸部がん(head and neck carcinoma) en-keyword=口腔がん(oral carcinoma) kn-keyword=口腔がん(oral carcinoma) en-keyword=頭頸部がんセンター(Head and Neck Cancer Center) kn-keyword=頭頸部がんセンター(Head and Neck Cancer Center) en-keyword=医科歯科合同手術(collaborative medical and dental surgeries) kn-keyword=医科歯科合同手術(collaborative medical and dental surgeries) en-keyword=顎骨再建(reconstructive operations of the jaw) kn-keyword=顎骨再建(reconstructive operations of the jaw) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=知的障害者歯科治療時の静脈内鎮静法におけるカプノメーターの有用性の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakayaKumiko en-aut-sei=Takaya en-aut-mei=Kumiko kn-aut-name=髙谷久美子 kn-aut-sei=髙谷 kn-aut-mei=久美子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=臨床経験がもたらす患者-研修歯科医間のコミュニケーションの変化 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OtsukaEri en-aut-sei=Otsuka en-aut-mei=Eri kn-aut-name=大塚恵理 kn-aut-sei=大塚 kn-aut-mei=恵理 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=矯正歯科未治療および治療済患者における口腔関連Quality of Lifeと各種歯科矯正学的指標の関連性 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KatoYui en-aut-sei=Kato en-aut-mei=Yui kn-aut-name=加藤ゆい kn-aut-sei=加藤 kn-aut-mei=ゆい aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=少数歯欠損患者における補綴歯科治療後6年経過時の口腔関連QOL評価 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KurosakiYoko en-aut-sei=Kurosaki en-aut-mei=Yoko kn-aut-name=黒﨑陽子 kn-aut-sei=黒﨑 kn-aut-mei=陽子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=6 article-no= start-page=147 end-page=149 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=201206 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=文献と臨床の橋わたし がん化学療法を受けている患者に対する口腔内管理の意義 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 中央診療施設医療支援歯科治療部 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=5 article-no= start-page=154 end-page=157 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=201305 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=もし、周術期口腔機能管理の依頼があったら? 周術期医療に歯科の専門性はどう役立つか? en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 中央診療施設医療支援歯科治療部 END start-ver=1.4 cd-journal=joma no-vol=34 cd-vols= no-issue=11 article-no= start-page=70 end-page=74 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=201011 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=医療の"いま"を伝える 周術期における医科-歯科連携 病院医療への歯科衛生士の参画 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 周術期管理センター歯科部門 END start-ver=1.4 cd-journal=joma no-vol=32 cd-vols= no-issue=2 article-no= start-page=57 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=201312 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Survey of first dental examination system for patients referred from medicine to dentistry in Okayama University Hospital ―FY2010 and 2011 report― kn-title=岡山大学病院歯科系診療科等が医科系診療科等から受けた院内紹介とそれに対する初動対応 ―平成22年度と23年度を対象とした実態調査― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name=山中玲子 kn-aut-sei=山中 kn-aut-mei=玲子 aut-affil-num=1 ORCID= en-aut-name=UdakaEmiko en-aut-sei=Udaka en-aut-mei=Emiko kn-aut-name=宇高恵美子 kn-aut-sei=宇高 kn-aut-mei=恵美子 aut-affil-num=2 ORCID= en-aut-name=YoshitomiAiko en-aut-sei=Yoshitomi en-aut-mei=Aiko kn-aut-name=吉冨愛子 kn-aut-sei=吉冨 kn-aut-mei=愛子 aut-affil-num=3 ORCID= en-aut-name=MatsumotoEriko en-aut-sei=Matsumoto en-aut-mei=Eriko kn-aut-name=松本江里子 kn-aut-sei=松本 kn-aut-mei=江里子 aut-affil-num=4 ORCID= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=5 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=森田学 kn-aut-sei=森田 kn-aut-mei=学 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 affil-num=2 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 affil-num=3 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 affil-num=4 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 affil-num=5 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 affil-num=6 en-affil= kn-affil=岡山大学病院医療支援歯科治療部 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=矯正歯科治療患者の口腔関連Quality of Lifeの評価 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KomoriHiroki en-aut-sei=Komori en-aut-mei=Hiroki kn-aut-name=古森紘基 kn-aut-sei=古森 kn-aut-mei=紘基 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=現在歯数と体重増加・肥満の発生の関連–企業歯科検診受診者を対象とした前向きコホート研究- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakiuchiHiroya en-aut-sei=Takiuchi en-aut-mei=Hiroya kn-aut-name=瀧内博也 kn-aut-sei=瀧内 kn-aut-mei=博也 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=2 end-page=3 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100901 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=移植後合併症の看護ポイント─GVHD③ 口腔GVHD en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=杉浦裕子 kn-aut-sei=杉浦 kn-aut-mei=裕子 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=前田嘉信 kn-aut-sei=前田 kn-aut-mei=嘉信 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 医療技術部(歯科部門) 歯科衛生士室 affil-num=2 en-affil= kn-affil=岡山大学病院 歯周科 affil-num=3 en-affil= kn-affil=岡山大学病院 血液・腫瘍内科 END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=1 article-no= start-page=37 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=200906 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Achievements and Next Themes of Dental Section of Perioperative Management Center in Okayama University Hospital at 5 Months after Establishment kn-title=岡山大学病院周術期管理センター(歯科部門)設立後5ヵ月間の活動内容および今後の展開 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name=山中玲子 kn-aut-sei=山中 kn-aut-mei=玲子 aut-affil-num=1 ORCID= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=曽我賢彦 kn-aut-sei=曽我 kn-aut-mei=賢彦 aut-affil-num=2 ORCID= en-aut-name=NawachiKumiko en-aut-sei=Nawachi en-aut-mei=Kumiko 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start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科インプラントにおける上部構造体の合着システムの開発―動的粘弾性挙動制御に基づく上部構造体浮き上がり量の抑制― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=BoRido en-aut-sei=Bo en-aut-mei=Rido kn-aut-name=宝力道 kn-aut-sei=宝 kn-aut-mei=力道 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=知的障害者歯科治療時におけるBispectral Index及びTarget-Controlled Infusionを用いた静脈内鎮静法の有用性の検討 kn-title=Dental Sedation for Patients with Intellectual Disability:A Prospective Study of Manual Control versus Bispectral Index-Guided Target-Controlled Infusion of Propofol en-subtitle= kn-subtitle= en-abstract= kn-abstract= 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en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=PRECEDE-PROCEED Model を用いた歯科保健行動、定期歯科健診受診に影響する要因の分析 kn-title=Analysis of the Factors That Affect Dental Health Behaviour and Attendance at Scheduled Dental Check-ups Using the PRECEDE-PROCEED Model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SatoKimiko en-aut-sei=Sato en-aut-mei=Kimiko kn-aut-name=佐藤公子 kn-aut-sei=佐藤 kn-aut-mei=公子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue= article-no= start-page=42 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=200903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Biochemical and histological effects of heat stress on experimental animals kn-title=暑熱ストレスによる実験動物の生化学的ならびに組織学的変化 en-subtitle= kn-subtitle= en-abstract= kn-abstract=暑熱環境が生体の生化学的変化に及ぼす影響について検討した。暑熱影響を生化学的観点からみると、肝臓における酸素ラジカルの生成が注目される。酸素ラジカルによる生体高分子との反応による脂質過酸化は生体膜や酵素の変性に結びつくため重要な障害反応と考えられるためである。ラット肝臓の脂質過酸化反応生成物の指標であるチオバルビツール酸反応生成物(TBARS)の濃度変化をみると、30℃では変化がなかった生成も、35℃の暑熱負荷では急激に増加した。ラットとモルモットを比較すると、モルモットは30℃においても若干の増加が認められ、35℃では顕著な増加が認められた。モルモットは暑熱への耐性が弱く暑熱負荷の長期的な実験は困難であった。肝臓細胞内小器官の脂質過酸化は若齢では影響を受けていなかったが、高齢・老齢ラットのミトコンドリア、ミクロゾームでは脂質過酸化が著しく誘導されていた。ラットでは肝臓の細胞質グルタチオンペルオキシダーゼは高体温症で強く誘導されたが、モルモットでは誘導がみられなかった。肝臓カタラーゼ活性は若齢のラットでは暑熱ストレスによる影響を受けていなかったが、高齢・老齢ラットは肝臓、腎臓のいずれの臓器においても減少していた。高齢・老齢ラットにおける肝細胞の小胞体は暑熱ストレスにより変形していたため、ミクロゾームの電子伝達系酵素のアミノピリン脱メチル化酵素やTMPDペルオキシダーゼ活性について検討した。その結果、加齢につれていずれの酵素も活性の低下がみられ、週齢の高いラットでは暑熱暴露によりさらに活性が低下した。暑熱ストレスにより合成する蛋白質の立体構造形成が不安定化することを防ぐ分子シャペロンとしての機能を示す熱ショックタンパク誘導にはモルモットとラットで種差があり、モルモットでは核とミトコンドリアで90-kDaの熱ショックタンパクの誘導が認められ、ラットの単離細胞においては70-kDaの熱ショックタンパクの合成促進が観察された。両種において暑熱ストレスによる細胞機能の変調に対して、分子シャペロン機能を示す防御系が活性化したと考えられる。実験動物に暑熱ストレスを加え、臓器・組織を光学顕微鏡と電子顕微鏡を用いて観察した結果、肝臓、腎臓、心臓、呼吸器系、内分泌系、免疫系などにおいて、暑熱ストレスにより組織的変化が認められた。特徴的な組織的変化は肝臓の静脈周辺細胞の空胞変性、脂質過酸化物に起因するとみられる脂肪顆粒の貯留、欝血などであった。さらに動物の加齢により暑熱ストレスの影響が増強し、適応性が低下していると考えられる老齢期ラットでは顕著に暑熱ストレスの影響があらわれた。35℃の暑熱環境下では、暴露期間が長くなるほど病理組織学的な諸変化が増強していた。臓器・組織における最も顕著な変化は静脈系の拡張であった。心筋の空胞変性とともに、肝臓、腎臓、心臓、肺および骨髄などに欝血の傾向が認められた。この研究により、暑熱ストレスが組織学的変化を伴う生体組織の障害を引き起こすことが判明した。暑熱ストレスの増大は生体諸機能の低下している高齢者や高齢の動物に対し深刻な影響を及ぼすと予想される。 en-copyright= kn-copyright= en-aut-name=AsanumaShinji en-aut-sei=Asanuma en-aut-mei=Shinji kn-aut-name=浅沼信治 kn-aut-sei=浅沼 kn-aut-mei=信治 aut-affil-num=1 ORCID= en-aut-name=SatoKatsunori en-aut-sei=Sato en-aut-mei=Katsunori kn-aut-name=佐藤勝紀 kn-aut-sei=佐藤 kn-aut-mei=勝紀 aut-affil-num=2 ORCID= en-aut-name=AndoMitsuru en-aut-sei=Ando en-aut-mei=Mitsuru kn-aut-name=安藤満 kn-aut-sei=安藤 kn-aut-mei=満 aut-affil-num=3 ORCID= en-aut-name=KawaharaIchisuke en-aut-sei=Kawahara en-aut-mei=Ichisuke kn-aut-name=川原一祐 kn-aut-sei=川原 kn-aut-mei=一祐 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=(財)日本農村医学研究所 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=富山国際大学 affil-num=4 en-affil= kn-affil=松本歯科大学 END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=12 article-no= start-page=43 end-page=50 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20101201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Surface-Based Registrationを利用した 3次元CBCTimageの重ね合わせとその応用例(1) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=高木雅人 kn-aut-sei=高木 kn-aut-mei=雅人 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田井規能 kn-aut-sei=田井 kn-aut-mei=規能 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佛坂斉祉 kn-aut-sei=佛坂 kn-aut-mei=斉祉 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=谷尻豊寿 kn-aut-sei=谷尻 kn-aut-mei=豊寿 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西山明慶 kn-aut-sei=西山 kn-aut-mei=明慶 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佐藤康守 kn-aut-sei=佐藤 kn-aut-mei=康守 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=たい矯正歯科 affil-num=2 en-affil= kn-affil=たい矯正歯科 affil-num=3 en-affil= kn-affil=長崎大学医歯薬総合研究科矯正学分野 affil-num=4 en-affil= kn-affil=メディックエンジニアリング affil-num=5 en-affil= kn-affil=岡山大学病院口腔外科(病態系) affil-num=6 en-affil= kn-affil=たい矯正歯科 END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=1 article-no= start-page=355 end-page=359 dt-received= dt-revised= dt-accepted= dt-pub-year=1955 dt-pub=19550131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科医を訪れて発見された単球性白血病の一症例 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=横原兼久 kn-aut-sei=横原 kn-aut-mei=兼久 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=武田勝美 kn-aut-sei=武田 kn-aut-mei=勝美 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部内科学教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=9 article-no= start-page=2357 end-page=2389 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=CLINICAL AND EXPERIMENTAL STUDIES ON PERIODONTOSIS AND HISTAMINE kn-title=歯槽膿漏症とヒスタミンの関係に関する臨床的並に実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=These studies were made for the purpose of finding out the relationship of periodontosis to histamine and the etiologic factors of the disease since the pharmacological action of histamine is very similar to the inflammatory state of periodontosis. The results obtained are summarized as follows: 1) Gingivae of 51 cases of periodontosis showed a threefold increase in histamine, compared with those of 20 control cases operated surgically in the oral cavity. It is suggested by these results, in conjunction with the histopathological observations, that periodontosis has a certain relationship to allergy. 2) In cases of periodontosis an increase in mast cells and their morphologic changes were noticed in the microscopic specimens when stained with a one per cent solution of toluidine blue. These findings are known to be positively correlated with an increase of histamine. 3) In the animal experiments an increase of gingival histamine could not be attributed to physico-chemical stimulation alone and it was not noted when a local anaphylaxis (allergy) was induced. However, it became particularly marked when the local anaphylaxis was compounded by the above-mentioned strong stimulation. These animals showed both macroscopic and microscopic changes suggestive of periodontosis. 4) In slight or early cases of periodontosis favorable results were obtained by topical applications of sinomenine and an anti-histamine ointment which were administered in order to eliminate excessive amounts of histamine in the gingiva. Therefore it may be concluded that periodontosis has a close relationship to histamine and allergy. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=藤岡幸雄 kn-aut-sei=藤岡 kn-aut-mei=幸雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=4 article-no= start-page=1047 end-page=1052 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Sepsis due to Deciduous Caries kn-title=乳歯齲蝕に起因する全身症状に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=One hundred and sixteen children, aged 2 to 11 years, who visited Department of Oral Surgery. Okayama University Medical School from July, 1955 to June, 1956 and had more than one deciduous carious teeth of C(3) or higher grade, were investigated and summarized. Forty-three did not have any systemic symptom suspectedly due to deciduous caries, while 71 had some systemic symptoms. The latter group was analyzed accordting to their age and the seasons when they had visited. During the same period, nine cases complaining of unknown fever or some kind of systemic disturbance who visited Pediatric Department first were referred to our Department, suspecting the deciduous caries as their causes. These cases were diagnosed as nephritis, rheumatic fever or allergic sepsis in the Pediatric Department and they had many deciduous caries of C(3) or higher grade. Then it could be found that the systemic symptoms disappeared after these suspicious teeth had been treated. This fact may reveal that apical lesion was frequently seen following deciduous caries and gave sometimes an onset to the severe systemic diseases. en-copyright= kn-copyright= en-aut-name=AkitaKazuo en-aut-sei=Akita en-aut-mei=Kazuo kn-aut-name=秋田和夫 kn-aut-sei=秋田 kn-aut-mei=和夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=11-2 article-no= start-page=7855 end-page=7860 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Various Techniques for Treating Alveolar Pyorrhoea kn-title=従来のもの及び私共の行つている歯槽膿漏症に対する治療方針とその検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In a previous report the anthors presented their suggestions for the surgical treatment of alveolar pyorrhoea. However, after further experience in a clinic established specifically for the treatment of this disease, new modes of treatment have been utilized and are reported upon in this paper. The authors discuss for removing the cause of the disease (systemic and local), symptomatic treatment (anti-inflammatory, repair of gingival pocket, and immobilization of loose teeth), supplementary and after-treatments; and they also reappraise the entire approach to the treatment of the disease. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=藤岡幸雄 kn-aut-sei=藤岡 kn-aut-mei=幸雄 aut-affil-num=1 ORCID= en-aut-name=FukuiTetsuya en-aut-sei=Fukui en-aut-mei=Tetsuya kn-aut-name=福井哲也 kn-aut-sei=福井 kn-aut-mei=哲也 aut-affil-num=2 ORCID= en-aut-name=SakuraiYasuro en-aut-sei=Sakurai en-aut-mei=Yasuro kn-aut-name=桜井靖郎 kn-aut-sei=桜井 kn-aut-mei=靖郎 aut-affil-num=3 ORCID= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=小林敏行 kn-aut-sei=小林 kn-aut-mei=敏行 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=11-2 article-no= start-page=7849 end-page=7853 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Suggestions on Surgical Treatment of Alveolar Pyorrhoea kn-title=歯槽膿漏症の外科的療法ならびにその適応に関する私見 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The nature of pathological changes in alveolar pyorrhoea is so complicated and varied, that there are many methods of attack in the treatment of this disease. For the clinicians who actually handle such cases, it is essential to select the most suitable treatment, so that recovery may be swiftly brought about. With this point in mind, the authors present their suggestions on surgical treatment, including gingival curettage, gingivectomy, flap operation of the gingiva (as well as its modified method), and tooth extraction. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=藤岡幸雄 kn-aut-sei=藤岡 kn-aut-mei=幸雄 aut-affil-num=1 ORCID= en-aut-name=FukuiTetsuya en-aut-sei=Fukui en-aut-mei=Tetsuya kn-aut-name=福井哲也 kn-aut-sei=福井 kn-aut-mei=哲也 aut-affil-num=2 ORCID= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=小林敏行 kn-aut-sei=小林 kn-aut-mei=敏行 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6210 end-page=6221 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar III. Histo-Pathological Study kn-title=下顎智歯周囲炎に関する研究 第3編 下顎智歯周囲炎の病理組織学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Biopsy was taken from the gingivae in 42 cases of pericoronitis and 8 normal healthy control cases, which were the same materials used in previous cytologic study. Sections were stained by Hematoxylin-Eosin, Azan and Papanicolaou methods, investigated histopathologically and compared with the findings of exfoliative cytology. 1) In normal gingivae keratinous layer could be seen in various degrees, while in acute inflammatory ones typical keratinous layer could not be observed and keratinization showed a decrease. 2) In Azan and Papanicolaou stainings yellow and red stainings decreased in the superficial layer and a definite correlation could be seen between keratinization and staining effect according to structural density of the tissue. Findings of exfoliative cytology and histo-pathology were completely agreed in their comaprison. 3) The SH groups of the surrounding tissue in case of pericoronitis were investigated by Chévremout-Erédéricq's reaction but a decisive conclusion could not be drawn from these results. It could be concluded that pericoronitis was induced by infection of the dental follicle after tooth eruption and could be divided into acute and chronic types clinically. As the results obtained from exfoliated epithelial cells classified according to their staining effect of the cytoplasm by Papanicolaou staining, a considerable decrease of keratinization could be noticed in cases of pericoronitis in comparison with normal controls. This fact could be proven by histo-pathological examination. Consequently clinical data, exfoliative cytogy and histo-pathology in case of pericoronitis coincided in their findings. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=松井儇行 kn-aut-sei=松井 kn-aut-mei=儇行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6197 end-page=6209 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar II. Exfoliative Cytologic Study kn-title=下顎智歯周囲炎に関する研究 第2編 下顎智歯周囲炎の剥離細胞学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Smear specimens were prepared from the inner surface of lower wisdom teeth of 20 normal healthy control cases and 252 cases of pericoronitis and stained by Papanicolaou and Giemsa. 1) Cytoplasm showed yellow, red mixed with blue or blue mixed with red, and blue according to the progress of keratinization by Papanicolaou staining. In chronic cases cells were more poorly stained than in normal control and acute cases. 2) Exfoliated epitheilail cells were classified accoding to keratinization or cytoplamic colors by staining and a definite relationship between progress of keratinization of acute and chronic cases could be statistically noticed as to rise and fall of the disease. The severer symptoms shows the inflammation. the lower tends the keratinization, and parabasal cells and atypical cells increased in their number as a specific finding. 3) Regressive changes were most remarkable in chronic cases, which were followed by acute and normal cases in the order. 4) The largest number of white blood cells could be seen in acute cases and as the disease proceeds to chronic type, they showed a decrease, which could be helpful to observation of the clinical progress. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=松井儇行 kn-aut-sei=松井 kn-aut-mei=儇行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6187 end-page=6196 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar I. Clinico-Statistical Observation kn-title=下顎智歯周囲炎に関する研究 第1編 下顎智歯周囲炎の臨床統計的観察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinico-Statistical findings were summarized in 252 cases of clinically diagnosed pericoronitis of the lower third molar. 1) Sex and Age Incidence: Generally speaking it could be seen a little more frequently in male, while more often in female before about 30 years of age, but a contrary tendency could be noticed with the progress of age. Eight per cent of all the cases were between the ages of 20 and 29 years. 2) Seasonal Incidence: It showed a decaease in the order of fall, spring, summer and winter. 3) Side Incidence: Almcst no difference of incidence could be seen between right and left sides. As for inclination of the eruption normal position was most frequent in acute cases, while mesial and horizontal inclincations more frequent in chronic cases. Twenty-eight per cent of all the cases showed the findings of bone resorption of the alveolar process. 4) Clinical Findings: They were almost agreed with those of previous description except lower incidence of disturbed mouth opening and fever which had been considered to be the most frequent symptoms so far. According to the clinical findings all the cases could be classified into acute and chronic ones at the ratio of 15 to 85. As a conclusion the fact that a cusp or a part of the crown had been exposed in all the cases examined may suggest that pericoronitis was due to infection of the dental follicle after eruption and had hardly connection with insufficiency of the space, direction of eruption, and difference of localiztion. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=松井儇行 kn-aut-sei=松井 kn-aut-mei=儇行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6145 end-page=6165 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Changes of Eosinophil Leucocytes in Alveolar Pyorrhea kn-title=歯槽膿漏症に於ける好酸球の消長に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hematological researches in peripheral blood, especially the changes of eosinophils were made from various points in order to solve the nature and etiology of alveolar pyorrhea. The results obtained are summarized as follows: 1) Little difference was recognized on red cell count, hemoglobin quantity and index in comparison with healthy control cases. No remarkable quantitative and qualitative changes of white cells except eosinophils were observed. In addition, any apparent difference between peripheral blood taken from the ear lobe and local gingiva could not be found in these above-mentioned points, 2) Increase of eosinophils was recognized in about 45 per cent of 78 cases, and, moreover, its remarkable relationship to clinical type, especially that of inflammatory findings characterstic of the disease, was suggested. Many cases showing morphological changes, especially degenerative changes of the cells, were observed, and, furthermore, relationlhip between changes of the cells and those of the disease conld be suggested as the experimental results 3) Peroxidizing reaction of the peripheral blood cells by the vitamin C method was investigated in 20 cases showing an increase of eosinophils. Consequently, quite difference could be observed in staining ability of granules between clinical cases and control cases, and thus it could be noticed that granules within the cells in case of alveolar pyorrhea were quantitatively different from those in normal ones. 4) As a result of vital observations on movement of eosinophils by the peripheral blood culture method in 10 cases of the disease, it was recognized that the migration velocity of the cells showed a rapid decrease as time went by and was markedly inferior to that of normal cases and that in the mobility form the cells suggestive findings of declining mobility increased much more than those of normal cases, especially showing a increasing tendency with the progress of culture. All of these various findings of the cells can not necessarily be considered to be the phenomena characteristic of this disease, but pathologic findings and characterics of the cells of this disease may suggest both correlation of the cells to chronic inflammatory changes in case of alveolar pyorrhea and possibility of allergic process as an etiologic factor of the disease. en-copyright= kn-copyright= en-aut-name=SakuraiYasuo en-aut-sei=Sakurai en-aut-mei=Yasuo kn-aut-name=桜井靖郎 kn-aut-sei=桜井 kn-aut-mei=靖郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6069 end-page=6088 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exfoliative Cytology of the Mouth Washings and Garglings kn-title=洗浄並びに含嗽による口腔剥離細胞に関する研究 第2編 病的口腔剥離細胞学 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Direct smear technic has been adopted in almost all the study on exfoliative cytology of the oral cavity, but cytology of the mouth washings and garglings has not been made so far. Therefore the author determined the most satisfactory centrifuging factors of the mouth washings and garglings to collect cells in the previous study. Now in this study cells were collected by means of centrifugation, membrane filter method and cell block method in normal healthy controls-25 newborns and sucklings, 30 adults. and 28 edentulous old persons with normal healthy oral cavity and in various clinical cases-24 malignancies, 6 benign tumors, 5 various other oral lesions, and 41 smokers. All the specimens were stained by Papanicolaou technic. I. NORMAL CYTOLOGY 1) Both nuclei and cytoplasms were larger in red and blue precornified epithelial cells, while somewhat smaller in orange keratinized cells showing pycnosis or disappearance of nuclei. 2) Fewer white blood cells were noticed in newborns, sucklings and old persons, while much more in the adults. These results may be due to the presence of gingival pockets, in other words the presence of teeth. 3) With the progress of age keratinized cells or those with keratinizing tendencies showed an increase, and those with regressive changes revealed the same findings. These results could be statistically proven significant and there was an aggreement between these cytologic and histologic findings. II. PATHOLOGIC CYTOLOGY Centrifugation 1) Most of the exfoliated malignant cells showed blue cytoplasm, which could be considered they were low-keratinized immature cells. 2) Of 21 cases confirmed of carcinoma by biopsy cytology-positive cases were 81 per cent in direct smear method and 52 per cent in centrifugation befor operation and 35 per cent in the former and 50 per cent in the latter after operation. 3) Sarcoma and other various lesions were cytology-negative, but plasmocytoma associated with intraoral ulceration revealed cytology-positive. 4) More keratinized cells or those with keratinizing tendency could be noticed in both edentulous and dentulous persons in smoker's group than in non-smoker's group. And it could be found that 15 cases, i.e. 62.5 per cent of 24 malignant cases were smokers. Cell Block Method Epithelial cells of both normal and pathologic oral cavity showed so marked morphologic changes that this method was not suitable for examination of cell elements. However, cells showed crowdings so that keratinizing tendency could be easily noticed at first sight by the difference of staining and the tumor cells could be distinctly observed. Membrane Filter Method No morphologic change could be seen and it was considred to be a useful method of diagnosis of malignancy, although cells overlapped each other. As a conclusion examination by centrifugation of the mouth washings and graglings was easy to collect cells, gave little irritation to the tissue and was a simple technic. It also could be repeated many times so that it was a very satisfactory method in cases of the following subjects: observation of postoperative progress, for example when the remnant of malignant tissue was suspected, examination of the cells after radiation therapy, early discovery of recurrence and examination of extensive lesions of the oral mucosa. en-copyright= kn-copyright= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=白石好夫 kn-aut-sei=白石 kn-aut-mei=好夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6059 end-page=6067 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=洗浄並びに含嗽による口腔剥離細胞に関する研究 第1編 正常口腔剥離細胞学 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=白石好夫 kn-aut-sei=白石 kn-aut-mei=好夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=5911 end-page=5920 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on Acatalasemia from the Viewpoint of Oral Surgery I. Exfoliative Cytology kn-title=無カタラーゼ血液症における歯科学的研究 I. 剥離細胞学的検索 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Exfoliative cytologic findings of the oral mucosa in three cases of Acatalasemia (Takahara's disease) were investigated by means of Papanicolaou's method. Three cases were sisters of the same family, 19, 22, and 15 years of age. Oroantral fistula was noticed in the left molar area in Case 2 and Case 3 complained of loosening of anterior lower teeth with marginal gingivitis in the left lower molar ares. Smears were prepared by the following technics: 1) Scraping four different areas of the oral mucosa---hard palate, gingiva, radix linguae and buccal mucosa without causing bleeding. 2) Sediment taken from centrifuged mouth washings by physiologic saline solution. 3) Cells caught by membrane filter or both of them. All the smears were stained by Papanicolaou's technic and histologic examination of the gingiva was made in comparison with cytologic smears in Case 3. Thus keratinization of the epithelial cells were studied. 1) Keratinizing tendency was the same as those of normal mucosa in Cases 1 and 3. In the ulcerating area of Case 3 keratinized cells showed an increase as healing was going on, while they showed a marked decrease in Case 2, which might be due to the decrease of local resitance associated with ulcerative changes and the influence of partial denture. 2) Exfoliated cells of the whole oral mucosa in case of mouth washings Cases 1 and 3 showed the same findings as normal cases and Case 2 showed a marked decrease of keratinized cells. These findings were same as those of four different areas of the oral mucosa. 3) Gingiva of Case 3 showed little difference from normal mucosa in histopathologic findings. en-copyright= kn-copyright= en-aut-name=WatanabeYoshio en-aut-sei=Watanabe en-aut-mei=Yoshio kn-aut-name=渡辺義男 kn-aut-sei=渡辺 kn-aut-mei=義男 aut-affil-num=1 ORCID= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=松井儇行 kn-aut-sei=松井 kn-aut-mei=儇行 aut-affil-num=2 ORCID= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=白石好夫 kn-aut-sei=白石 kn-aut-mei=好夫 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=6-2 article-no= start-page=3419 end-page=3423 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590515 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship of Centrifuging Round to Disintegration of the Exfoliated Cells in Mouth Washings kn-title=含嗽液中の剥離細胞の破壊と遠心沈澱の回転数との関係 en-subtitle= kn-subtitle= en-abstract= kn-abstract=No study has been found on exfoliated cells in the mouth washings, while some have been made on exfoliative cytology of the mouth. For the purpose of investigation of exfoliated epithelial cells in the mouth washings by physiologic saline solution, preliminary study was made on effective factors in centrifuging rounds and time, staining, and changes of cell morphology by the use of mouth washings taken from the normal oral cavity with healthy teeth. Mouth washings were centrifuged for 5, 10, or 30 minutes at 1,000 r.p.m., 2,000 r.p.m. or 3,000 r.p.m. Washings were mixed immediately with 50 per cent alcohol or 95 per cent alcohol in comparison with those mixed with no alcohol. Each of materials was kept under the room temperature or in an incubator and examined consecutively concerning staining effect and changes of cell morphology. The results obtained are as follows: 1. The stable condition in staining effect and cell morphology was obtained in case of mixing with an equal quantity of 50 per cent alcohol immediately after mouth washings were taken and of 10-minute centrifugation at 2,000 r.p.m. And these smears could be stained and differentiated even 48 hours later in stable conditions. 2. Leucocytes were liable to be disintegrated more than 30 minutes after materials had been taken, while epithelial cells were not disintegrated. 3. When no alcohol was mixed, staining effect decreased rapidly 24 hours later, cell disintegration was marked and cell count could not be done successfully. en-copyright= kn-copyright= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=白石好夫 kn-aut-sei=白石 kn-aut-mei=好夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=9-10 article-no= start-page=1167 end-page=1173 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199010 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Electron beam therapy in carcinoma of the buccal mucosa kn-title=頬粘膜癌に対する電子線治療法の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects including, stomatitis and dermatitis are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. en-copyright= kn-copyright= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=1 ORCID= en-aut-name=MiyakeHideaki en-aut-sei=Miyake en-aut-mei=Hideaki kn-aut-name=三宅英昭 kn-aut-sei=三宅 kn-aut-mei=英昭 aut-affil-num=2 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=3 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=4 ORCID= en-aut-name=InamuraKeiji en-aut-sei=Inamura en-aut-mei=Keiji kn-aut-name=稲村圭司 kn-aut-sei=稲村 kn-aut-mei=圭司 aut-affil-num=5 ORCID= en-aut-name=MimuraSeiichi en-aut-sei=Mimura en-aut-mei=Seiichi kn-aut-name=三村誠一 kn-aut-sei=三村 kn-aut-mei=誠一 aut-affil-num=6 ORCID= en-aut-name=OhkawaYoshihiro en-aut-sei=Ohkawa en-aut-mei=Yoshihiro kn-aut-name=大川義弘 kn-aut-sei=大川 kn-aut-mei=義弘 aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= en-aut-name=FujikiTomokazu en-aut-sei=Fujiki en-aut-mei=Tomokazu kn-aut-name=藤木知一 kn-aut-sei=藤木 kn-aut-mei=知一 aut-affil-num=10 ORCID= en-aut-name=KishiKanji en-aut-sei=Kishi en-aut-mei=Kanji kn-aut-name=岸幹二 kn-aut-sei=岸 kn-aut-mei=幹二 aut-affil-num=11 ORCID= en-aut-name=ChiharaNaoto en-aut-sei=Chihara en-aut-mei=Naoto kn-aut-name=千原直人 kn-aut-sei=千原 kn-aut-mei=直人 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学歯学部歯科放射線学講座 affil-num=11 en-affil= kn-affil=岡山大学歯学部歯科放射線学講座 affil-num=12 en-affil= kn-affil=岡山大学歯学部第二口腔外科学講座 en-keyword=頬部粘膜癌 kn-keyword=頬部粘膜癌 en-keyword=電子線治療 kn-keyword=電子線治療 en-keyword=後方散乱線 kn-keyword=後方散乱線 en-keyword=mouthpiece kn-keyword=mouthpiece END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科臨床における感染予防対策意識と行動についての現状と課題 -某県歯科衛生士会会員に対する意識調査から- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeAkari en-aut-sei=Watanabe en-aut-mei=Akari kn-aut-name=渡辺朱理 kn-aut-sei=渡辺 kn-aut-mei=朱理 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue= article-no= start-page=31 end-page=35 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=200209 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Evaluation of Availability of New Experiment Technique for Cervical Spinal Cavity Administration in Rats -Examination by Behavioral Pharmacological Study of Inducing Anesthetic Potentiation- kn-title=新たな実験手技・ラット頚部髄腔内投与法の有用性の評価―麻酔増強作用による行動薬理学的試験での検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=ラットの硬・クモ膜下腔内への投与方法としては、従来からカテーテル設置による大槽内投与法が汎用されている。しかし、これらの大槽内投与法は、投与前に手術などの事前処置や回復の時間が必要なことなどの制約があるため,速やかに投与を開始することや短時間に多数のラットへ投与することなどが困難である。そこで、我々はラットの後頭部から経皮的に頚部髄腔内へ穿針する投与法である頚部髄腔内投与法を開発した。今回は、その有用性を麻酔薬や催眠導入剤のスクリーニングに用いられる麻酔増強作用により検討を行った。麻酔増強作用は塩酸ケタミンならびにペントバルビタールナトリウムを用いて、チオペンタールナトリウム麻酔増強作用により行った。その結果、頚部髄腔内投与法は大槽内投与法に比べ、ストレス無く投与できること。すでに汎用されている大槽内投与法投と同様の薬理学的評価が得られた事などから、頚部髄腔内投与法は大槽内投与法に代わるラットの硬・クモ膜下腔内への投与方法としての可能性が示唆された。 en-copyright= kn-copyright= en-aut-name=MuranakaKiyoshi en-aut-sei=Muranaka en-aut-mei=Kiyoshi kn-aut-name=村中清志 kn-aut-sei=村中 kn-aut-mei=清志 aut-affil-num=1 ORCID= en-aut-name=SagaraEiji en-aut-sei=Sagara en-aut-mei=Eiji kn-aut-name=佐加良英治 kn-aut-sei=佐加良 kn-aut-mei=英治 aut-affil-num=2 ORCID= en-aut-name=KurabayashiYuzuru en-aut-sei=Kurabayashi en-aut-mei=Yuzuru kn-aut-name=倉林譲 kn-aut-sei=倉林 kn-aut-mei=譲 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=株式会社アニマルケア affil-num=2 en-affil= kn-affil=九州歯科大学動物実験施設 affil-num=3 en-affil= kn-affil=岡山大学医学部附属動物実験施設 END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=5 article-no= start-page=211 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=1956 dt-pub=19560531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The statistical observations of the out-patients and in-patients during five years since the opening of the Department of Oral Surgery, Okayama University Medical School kn-title=岡山大学医学部歯科学教室開講5ケ年間に於ける外来患者並びに入院患者の統計的観察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The statistic observations were made about the inpatients and out-patients of the department of oral surgery, okayama university medical school during full five years from July in 1950 to June in 1955. The out-patients were classified into those of inflammation (pulpitis and gingivitis excepted), of caries (which was divided into what needed canal treatment and what was not so serious), of pyorrhea alveolaris, of gingivitis, of tumour, and of other diseases, and then each disease group was observed according to the difference year, season, tooth, sex, age, and occupation. Thereby, comparatively remarkable, interesting, statistical, numeral values were not only obtained concerning to each disease, but also the characteristics of the department of oral surgery of the attached hospitals of our government universities were apparently recognized here also. As the total number of the in-patients was only 237, the detailed statistical report being reserved, they were observed only according to the difference of year and disease. Thereby, inflammation and tumour were so many that they occupied about 80% of the number of all the in-patients. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=藤岡幸雄 kn-aut-sei=藤岡 kn-aut-mei=幸雄 aut-affil-num=1 ORCID= en-aut-name=OnoHajime en-aut-sei=Ono en-aut-mei=Hajime kn-aut-name=小野一 kn-aut-sei=小野 kn-aut-mei=一 aut-affil-num=2 ORCID= en-aut-name=NishijimaKatsumi en-aut-sei=Nishijima en-aut-mei=Katsumi kn-aut-name=西嶋克巳 kn-aut-sei=西嶋 kn-aut-mei=克巳 aut-affil-num=3 ORCID= en-aut-name=KagawaGaiji en-aut-sei=Kagawa en-aut-mei=Gaiji kn-aut-name=香川凱二 kn-aut-sei=香川 kn-aut-mei=凱二 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部歯科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部歯科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=2829 end-page=2884 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Absorption Activity of the Oral Mucosa kn-title=口腔粘膜の吸収能に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=By the use of trypan blue, i.e. lipoid insoluble acid stain, in order to make observation of absorption activity of the oral mucosa, animals' mucosa with rapid absorption activity, its location, absorbing process, and absorbing conditions were investigated. Then clinical and biological observation on absorption of hormone of the salivary gland was tried. Ⅰ. Mixture containing equal parts of 1 per cent solution of trypan blue and saturated sodium bicarbonate solution was dropped and painted over the normal oral mucosa of various kinds of animals, such as dog, cat, hamster, albino rat, chicken, elaphis virgatus, lizard, rana esculenta, eft, and crusian and absorption of the solution was observed. The results obtained were as follows: 1) Absorption varied according to the kinds of animals. 2) In general absorption of the lower verbetrata was more remarkable than that of mammals and birds. 3) In mammals that of dogs was more marked than that of cat, hamster and albino rat. 4) In dogs marked absorption was seen in buccal and sublingual mucosa, particularly at the sublingual and parotid salivary papillae and their surrounding areas. 5) In albino rats absorption was made at the hard palate corresponding to the tip of the tongue. Ⅱ. In premature dogs it was equal to that of mature dogs. Ⅲ. No absorption was seen in the oral mucosa of the dog's and rabbit's fetus, while slight one was seen around the erupted teeth of the guinea-pig's fetus. Ⅳ. T.B. was not introduced into the ep. cells of rabbit's oral mueosa in case of vital staining. Ⅴ. The effects of various factors on T.B. absorption of the oral mucosa in dogs' experiments were as follows: Absorption-stimulating factors are, local thermal stimulation, Grace helio lamp irradiation. roentgen irradiation of amount of 60 r to 100 r, radium irradiation of amount of 33 mg. h, to 66 mg. h., intracranial amputation of maxillary and mandibular divisions of trigeminal nerve just after the procedure. and local injection of Teabrom (T.E.A.B.), in the early stage of injection, while absorption-inhibiting factor was local cold stimulation and no absorption was stimulated in case of anemia of the head following ligation of the common carotid artery. Ⅵ. Parotin and Saliva-parotin, i.e. hormone of the salivary gland was painted over the oral mueosa of man, clog and rabbit. The results obtained were as follows: 1) Leucocytosis was noticed in cases of dog (1.2~5.0 mg./kg. of Parotin administered) and man (0.2~0.4 mg./kg. of Parotin or 0.1-0.2 mg./kg. of Saliva-parotin administered), 2) decrease of serum Ca. and leucocytosis in case of rabbit (1.0-5.0 mg./kg. of Parotin and Saliva-parotin administered), and 3) stimulated calcification of dentine in case of rabbit (5 mg./kg. of Parotin administered). These results Will suggest us the following factors as those effecting on absorbing mechanism of the oral mueosa, especially of the epithelium: 1) resistance, 2) intensity of surface tension, 3) intercellular density, 4) characteristics of chemical substances and solvent, and 5) special vital function of the cells. en-copyright= kn-copyright= en-aut-name=IdeiKiyoo en-aut-sei=Idei en-aut-mei=Kiyoo kn-aut-name=出井清雄 kn-aut-sei=出井 kn-aut-mei=清雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=4 article-no= start-page=1191 end-page=1215 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on the Mottled Deciduous Tooth kn-title=乳歯斑状歯の研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Attention has been paid to the mottled tooth since the report of Black and McKay in 1916. Thereafter the developing mechanism of mottled teeth has been made clear to some extent by many examinations and studies, but the majority of them is that of the permanent tooth and very few works have been made on the deciduous tooth. What these few works agree in their opinions with each other is that incidence of mottled deciduous teeth is lower than that of permanent ones, but the reason for this difference is still in the stage of speculation. The results of clinical and experimental studies on the mechanism of development of mottled deciduous teeth are described in this paper. Material and Methods: The Th-Neo-Thorin Method was used for determination of fluorine. All the materials used were distilled and only the fluorine ion was isolated. 1) Numerous cases of mottled deciduous teeth were discovered when investigation of mottled teeth had been carried out in Tomita District, Tamashima City and Konko Town in Okayama Pref. in 1953. The results obtained from the studies on the relationship between their incidence and caries of deciduous teeth and on determination of the fluorine content in drinking water are as follows: a) Average number of the persons with mottled teeth was 47.84 per cent in the permanent teeth and 15.23 per cent in the deciduous teeth, in the ratio 3 to 1. And the degree of mottled teeth was M(1) in most cases and M(2) in few cases and no M(3) could be found. b) Minimal threshold of fluorine in the incidence of mottled teeth was approxiamtely 1.0 ppm. in the deciduous teeth, while 0.5 ppm. of fluorine caused mottled teeth of degree of M(1). c) Caries incidence of the deciduous teeth was as low as that of the permanent teeth; and caries incidence in case of mottled deciduous teeth was lower than that in case of permanent ones. 2) The following experiments were performed for the purpose of investigating the role the placenta played in the fluorine metabolism during pregnancy: First, the fluorine content in the placenta of pregnant women and in the drinking water taken by them selves during the pregnancy were determined both in fluorine and non-fluorine districts. Then oral examinations of the children of the mothers in the fluorine district were conducted. And the rationship of incidence of the mottled deciduous teeth to the content of fluorine in the placenta and in the drinking water was investigated and the fluorine content of the deciduous teeth was determined at the same time. The results obteined were as follows: a) When the mother took a large amount of fluoride, some of fluorine was retained in her placenta, while the rest pessed through the placenta and had an effect on the embryo. b) The higher was the content of fluorine in drinking water, the larger was the amount of fluorine retained in the placenta. c) A small amount of fluorine could be recognized in the control placenta taken from the non-fluorine district. d) Incidence of mottled deciduous teeth was dependent upon the fluorine content of drinking water. e) The larger the content of fluorine in drinking water, the more frequently seen the incidence of mottled deciduous teeth with its minimal threshold of 1.0 ppm. f) Fluorine of 334.4 ppm. on average was contained in the mottled deciduous teeth, i.e. about one third of fluorine in the mottled deciduous teeth. 3) The following animal experiments were performed in order to confirm those results mentioned above in human: Rabbits were used as experimental animals to investigate what amount of fluorine was retained in the placenta and to what extent it was transmitted to her embryo and, moreover, to determine whether there was any limit in the retention of fluorine within the placenta. a) When 0.5 mg./kg. or 1.0 mg/kg. of NaF was administered, no significant change was noticed in the fluorine content of the placenta as compared with that of the control, but maked retention of fluorine was seen, when 5.0 mg./kg. or more of NaF was given. b) When a large amount of NaF, ranging 10.0 mg./kg. to 20.0 mg./kg. was administered, fluorine passed through the placenta and was transmitted to the embryo. From the results obtained by these experiments it could be concluded that the placenta plays a definite role in fluorine metabolism during the pregnancy and its retention has an influence on the incidence of mottled deciduous teeth. en-copyright= kn-copyright= en-aut-name=WatanabeShimpei en-aut-sei=Watanabe en-aut-mei=Shimpei kn-aut-name=渡辺信平 kn-aut-sei=渡辺 kn-aut-mei=信平 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=407 end-page=423 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Caries Incidence in the First Molar in Relation with Amount of Sugar Consumption on Primary School Children in Kyoto kn-title=京都市小学校児童第一大臼歯の齲蝕発病と砂糖消費量とに関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The relation between caries incidence and sugar consumption was cleared up by Takeuchi and Takahashi with the material of primary school children in Tokyo under the view point of the dental caries that should be observed by the rate of caries incidence as "one tooth as unit" and during a limited period, because the caries develop on the tooth as unit and never be healed spontaneously. The author, for the supplement study, observed the relation between sugar consumption and the rate of caries incidence during a year with a Cohort observation of the cases and analysed a pattern of the caries incidence in the first molar of 10,553 chidren who were born between 1924 and 1946, admitted into a school between 1931 and 1953 of 14 primary shools in Kyoo. The results were as follows: (1) Accumulated sugar consumption during the maturation period of teeth has only slight influence upon caries incidence.(2) The relation between sugar consumption for a year of new caries incidence in the first molar and the rate of new caries incidence for a year are extremely close and correlation coefficient of the average rate of caries incidence during 6-11 years of age to sugar consumption are: for example, in the lower first molar the year of the new caries incidence, the year before, and the year before last are respectively 0.8, 0.8 and 0.7. Also it was presumed that the type of quantitative relation on the semi-log graph shows a almost straight line. On this point this is almost as same as a results of Takeuch and Takahashi theoretically but it shows a little more slow curve and a smaller number. (3) With the materials during the years before the world war Ⅱ. I had made an age pattern of the rate of caries incidence in the first molar for 6-11 years of age. Using this pattern, I drew the model picture of the rate of caries incidence for a Cohort of which had a change of sugar consumption during the year. I had learned that it is possibly similar to the picture of the caries incidence for a year, which is drew with real Cohort. According to this result, with the model picture, I had learned the caries incidence for a year has extremely close relation with the sugar consumption during the year. Also it is presumed that an influence of the caries incidence on the individual tooth will always show a same age pattern without an influence of the sugar consumption. en-copyright= kn-copyright= en-aut-name=KoikeHiromu en-aut-sei=Koike en-aut-mei=Hiromu kn-aut-name=小池弘 kn-aut-sei=小池 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=東京歯科大学衛生学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=387 end-page=406 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Histamine Content of the Saliva kn-title=唾液ヒスタミン含量に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A number of work on the saliva has been made by many authors, but chemical investigations particuarly on histamine of the saliva are few. Only those by Feldberg, Kamenowa, Sanders and Ungar et al. could be found. However, there has been no study on the histamine content of saliva at the onset of diseases in the oral cavity and its fluctuation at various kinds of surgery. Now quantiative determination was made on histamine content of the saliva in normal and pathological conditions of the oral cavity, and the relationship between the histamine content and the findings of exfoliative cytology was also investigated. One hundred and forty-five patients were examined: 46 of normal healthy control, 26 of acute inflammation, 37 of chronic inflammation, 6 of chronic non-inflammatory lesion, and 30 of minor surgery. Parotid saliva collected by Umemoto-Kakudo's Aspirator and mixed resting saliva were used as test materials. Assay of histamine was made by biological determination by means of Magnus' Apparatus after extraction of histamine by Code's Methode and then Mayeda's Method by neoantsrgan was adopted. In normal healthy controlshistamine contents of the parotid saliva and the mixed saliva were 0.015±0.002 μg/c.c. and 0.034±0.003 μg/c.c. respectively, which were almost equal to those in cases of slight degree of caries or edentulous jaws. In acute inflammation they were 0.036±0.002 μg/c.c. and 0.122±0.016 μg/c.c.. Histamine in the mixed saliva was markedly increased. In chronic inflammation they were 0.026±0.003 μg/c.c. and 0.119±0.019 μg/c.c.. Histaminee in the mixed saliva was increased especially in superficial and extensive lesions. In chronic non-inflammatory lesions they ware 0.018±0.004 μg/c.c., and 0.040±0.013 μg/c.c.. An increase of exfoliated epithelial cells, lescocytes, especially neutrophils, and bacilli were observed in acute inflammatory leasians with particulary high histamine content in the saliva. At the time of various procedures of oral surgery almost no change was observed in the parotid. saliva, while higher histamine content was noticed in the mixed saliva in major surgery than in minor one. Some considerations and discussions were made on the problems of histamine release and on the use of antihistamine preparations from the results obtained and the review of previous litrature. en-copyright= kn-copyright= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=小林敏行 kn-aut-sei=小林 kn-aut-mei=敏行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=153 end-page=174 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Study on Vascularization of Blood Vessels in Postexodontic Wounds kn-title=抜歯創の血管新生に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=By means of stereoscopic microscopy morphologic observation was made on vascularization of the blood vessels during the progress of postexodontic wound healing in 37 mature dogs. Imagawa's Guttapercha Infusion Method was adapted and macroscopic and radiographic observations were combined. In the wounds of 86 normal tooth extractions more remarkable vascularization could be noticed in the wound openings than in the apical areas in the early postexodontic stage. During the period of 10 to 14 days after extraction gingival mucosa covered the wound and capillary vascularizations were completed. Tendency of vascularization in postexedontic wound healing was fundamentally identical with those of descriptions by Clark and Akita: capillary buds formed, capillary loops newly developed, and then capillary networks completed. In the wounds of 50 extractions with apical foci experimentally made, capillary networks were dense in the wound opening, while they were loosened in the apical areas with a distinct difference between them in the early postexodontic stage. In the later stages, however, vascularization seemed to show a tendency of slight delay in comparison with normal healthy controls. In adittion, the effect of gauze packing and insertion of penicillin dental cone upon the wound healing was investigated. en-copyright= kn-copyright= en-aut-name=MakiRyoji en-aut-sei=Maki en-aut-mei=Ryoji kn-aut-name=真木亮二 kn-aut-sei=真木 kn-aut-mei=亮二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=53 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Exfoliative Cytology in Case of Leprosy Ⅱ. Oral Exfoliative Cytology in Leprosy kn-title=癩患者における口腔剥離細胞学的研究 第2編 癩患者の口腔剥離細胞学 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In 152 in patients of the Aisei-en Leprosarium comparative studies were made on keratinization, degenerative changes, and N/C ratio with those in normal contorols. In addition, leprosy cells were proven on aspirated smear specimens taken from leproma of the face and upper extremity and their N/C ratio was compared with those of normal oral epithelial cells. 1. In leprosy keratinization was less and degenerative change of the exfoliated epithelial cells are higher than in normal. This could be proven histopathologically. 2. These changes did not show a difference between leprosy types. 3. The N/C ratio of exfoiiated epithelial cells showed no difference between normal and leprosy cases. 4. In detection of leprosy cells in aspiration the Ziehl-Neelsen method was highest in its detection percentage, which was followed by hematoxylin-eosion and Papanicolaou technics. 5. In leprosy cells the N/C ratio showed a decrease as the size of the cells showed an increase. 6. The N/C ratio showed a difference between normal epithelial cells and leprosy cells. 7. Papanicolaou technic can be considered a supplementary practical method in detection of leprosy cells in combination with Ziehl-Neelsen's method. en-copyright= kn-copyright= en-aut-name=HidakaToyozo en-aut-sei=Hidaka en-aut-mei=Toyozo kn-aut-name=日高豊蔵 kn-aut-sei=日高 kn-aut-mei=豊蔵 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=45 end-page=51 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Exfoliative Cytology in Case of Leprosy I. Normal Exfoliative Cytology kn-title=癩患者における口腔剥離細胞学的研究 第1編 正常人の口腔剥離細胞学 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Exfoliated epithelial cells of oral mucosa of 15 normal healthy individuals were taken as smear specimens from various intraoal areas and their garglings and stained by Papanicolaou technic. Keratinization, degenerative changes, and nuclear-cytoplasmic ratio (N/C) were studied in each smear. 1. A decrease of keratinized epithelial cells was noticed in the order of hard palate, gingiva, base of the tongue and buccal mucosa. 2. In the garglings more non-keratinized and precornified blue and red cells were exfoliated, while fewer keratinized orange cells. 3. Areas of the cytoplasm and nncleus of the exfoliated epithelial cells were mearsured and classified into small, middle, and large cells. 4. The N/C ratio was noticed to show a decrease in th order of small, middle and large cells. en-copyright= kn-copyright= en-aut-name=HidakaToyozo en-aut-sei=Hidaka en-aut-mei=Toyozo kn-aut-name=日高豊蔵 kn-aut-sei=日高 kn-aut-mei=豊蔵 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=1-3 article-no= start-page=1 end-page=24 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19630330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ELECTRON MICROSCOPIC STUDY ON THE ORAL EXFOLIATED EPITHELIAL CELLS kn-title=口腔剥離細胞の電子顕微鏡的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electron microscopic observation was applied to both twenty cases of normal mucosa and eighteen cases of squamous cell carcinoma of the oral cavity and their exfoliative cytologic findings were investigated in comparison with the histologic findings. Ⅰ. TISSUE CELLS Desmosome, which are regarded as a universal structure of cohesion of epithelial cells, was much poorer in carcinoma cells than in normal ones and intercellular spaces displayed a marked variation in width in carcinoma tissue cells. Thus intercellular cohesion was morphologically very poor and loose in carcinoma. In both cells an intercellular border was distinct and no syncytium was found to be formed. Tonofilaments, which can be distinctly found in normal cells, could not be noticed and a higher development of endoplasmic reticulum and mitochondria was shown in carcinoma cells. However, the mitochondria of carcinoma cells was remarkable in degenerative findings and was larger in size than that of normal cells. There was a strong resemblance between basal cells of the normal tissue and carcinoma cells in an indefinite nuclear shap and a decrease of cytoplasmic: nuclear ratio. In carcinoma cells a fine structure of their nuclear membrane was well-preserved and their nucleoli could be remarkably noticed. Ⅱ. EXFOLATED CELLS In normal cells spinous processes of almost definite size and shape were extending regularly around them, while in carcinoma cells poorer processes of various shape and size were extending irregularly around them or sometimes they were missing. Mechanical destruction was particularly marked in the area of peripheral cytoplasm of normal cells of the deeper layer under the superficial spinous cell layer probably because of a tight intercellular cohesion. Generally speaking, findings of tonofilament, endoplasmic reticulum and mitochondria corresponded to those of tissue cells in both normal and carcinoma cells, while a slightly severer degeneration of intra-cytoplasmic organelles in exfoliated carcinoma cells could be noticed in comparison with carcinoma tissue cells. A fine structure was well-preserved in nuclei of carcinoma cells, but disintegration and disappearance of the nuclear membrane could be noticed in severely degenerated carcinoma cells and no thickening of the nuclear membrane could be found. From these results obtained the cytologic findings of the smear in Papanicolaou staining and electron microscopy were compared and discussed. en-copyright= kn-copyright= en-aut-name=KobayashiToshiro en-aut-sei=Kobayashi en-aut-mei=Toshiro kn-aut-name=小林敏郎 kn-aut-sei=小林 kn-aut-mei=敏郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=1-3 article-no= start-page=123 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=1962 dt-pub=19620330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Study on Capillary Vascularization in the Periodontal Tissue following Gingivectomy and Flap Operation kn-title=歯槽膿漏症手術創の血管新生に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Sixty five normal mature dogs weighing about 5 to 10Kg. fed on under the same condition were used. Gingivectomies were performed in the area of lower anterior teeth, while flap operation in the area of upper anterior teeth in the same dog. Healing process of operated gingivae was followed up during twenty-eight days after operative procedure. Imagawa's gutta percha perfusion methode was adopted for observation immdeiately after, 1day, 3, 7, 14, 21 and 28 days after operation consecutively, and then heads of sacrificed dogs were fixed in 10 percent formalin solution. Transparent specimens were prepared from the operated tissue for stereoscopic observation, while histologic specimens were stained with hematoxylin-eosin by a routine paraffin methode simultaneously. The result obtained were as followed: 1) Vascularization during wound healing of the operated gingiva, alveolar bone and periodontal membrane was fundamentally identical with description by Clark and Akita: new capillary loops which developed from capillary buds connected each other and built a capillary net work on the seventh days and then some capillaries disintegrated. 2) Clusters of capillary loops which developed in the granulation tissue were mainly supplied by the blood vessels of the periodontal membrane especially in the case of gingivectomy. Thus it could be considered that blood vessels of periodontal membrane would play the most important role in the blood supply for the newly formed gingiva in the early stage. 3) Newly formed blood vessles of the gingiva and periodontal membrane as well as branch vessels among of capillary loops were connected each other fourteen days after operation, 4) Reattachment of gingiva to cemeutum was noticed two weeks after operation. At this period capillary loops, which had developed in the wound of flap operations, built capillary net works at the area internal gingival epithelial margin (innere Saumepithel) and were shortened and came closer to cementum at the area where internal gingival epithelial margin attached. It would be considered that this process would stimulate the vitality of cementum and had some relationship in organic union of the connective tissue with cementum. 5) Wound healing was remarkably delayed at gingival papillae, where normal vascularization could not be noticed 28days after operation. Thus it would be better for us to use surgical packs after operation and gingival massage seemed to stimulate normal vascularization. en-copyright= kn-copyright= en-aut-name=SuzukiSatoshi en-aut-sei=Suzuki en-aut-mei=Satoshi kn-aut-name=鈴木達志 kn-aut-sei=鈴木 kn-aut-mei=達志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部歯科学教室 END start-ver=1.4 cd-journal=joma no-vol=81 cd-vols= no-issue=3-4 article-no= start-page=135 end-page=141 dt-received= dt-revised= dt-accepted= dt-pub-year=1969 dt-pub=19690430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Report of Field Survey on Acatalasemia and Hypocatalasemia in 1966 and 1967 kn-title=昭和41年および42年度Acatalasemia, Hypocatalasemia調査集計 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of field survey and family follow-up on acatalasemia and hypocatalasemia during the years of 1966 and 1967. Thirty-seven hypocatalasemias were seen in the tests of 11,875 individuals at Chiba Prefecture including the examinees tested in 1965. Thus, the rate of incidence at Chiba amounted to 0.31%. The test on students of Okayama University revealed two hypocatalasemias among 2,526 (0.08%). Oki Is. contained seven hypocatalasemias among their 4,831 school-children. And no hypocatalasemic individuals were found out among 2,682 inhabitants of Okinawa Is., Ryukyu. Formosa, however, showed rather high incidence rate such as 0.28%, 60 hypocatalasemias among 21,789 inhabitants. In 1966 and 1967, three acatalasemias of two families, one of them already reported in 1965, were added to the formerly known cases. Consequently, the total of reported acatalasemias were 93 cases of 44 families by the end of 1967. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=高原滋夫 kn-aut-sei=高原 kn-aut-mei=滋夫 aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=2 ORCID= en-aut-name=KoyamaTakashi en-aut-sei=Koyama en-aut-mei=Takashi kn-aut-name=小山高司 kn-aut-sei=小山 kn-aut-mei=高司 aut-affil-num=3 ORCID= en-aut-name=KishimotoHiroyuki en-aut-sei=Kishimoto en-aut-mei=Hiroyuki kn-aut-name=岸本浩之 kn-aut-sei=岸本 kn-aut-mei=浩之 aut-affil-num=4 ORCID= en-aut-name=ChibaKazuo en-aut-sei=Chiba en-aut-mei=Kazuo kn-aut-name=千葉和夫 kn-aut-sei=千葉 kn-aut-mei=和夫 aut-affil-num=5 ORCID= en-aut-name=SadamotoMasanori en-aut-sei=Sadamoto en-aut-mei=Masanori kn-aut-name=貞本昌規 kn-aut-sei=貞本 kn-aut-mei=昌規 aut-affil-num=6 ORCID= en-aut-name=TakehisaToru en-aut-sei=Takehisa en-aut-mei=Toru kn-aut-name=竹久亨 kn-aut-sei=竹久 kn-aut-mei=亨 aut-affil-num=7 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=三谷恭夫 kn-aut-sei=三谷 kn-aut-mei=恭夫 aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=9 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=笠井英夫 kn-aut-sei=笠井 kn-aut-mei=英夫 aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=11 en-affil= kn-affil=東京医科歯科大学人類遺伝学研究室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=7-8 article-no= start-page=259 end-page=265 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19710830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=昭和43年度および44年度Acatalasemia, Hypocatalasemia調査集計 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=高原滋夫 kn-aut-sei=高原 kn-aut-mei=滋夫 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小野田元男 kn-aut-sei=小野田 kn-aut-mei=元男 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大島昭夫 kn-aut-sei=大島 kn-aut-mei=昭夫 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=住田昭三 kn-aut-sei=住田 kn-aut-mei=昭三 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=滝口峻 kn-aut-sei=滝口 kn-aut-mei=峻 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=尾関安英 kn-aut-sei=尾関 kn-aut-mei=安英 aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=笠井英夫 kn-aut-sei=笠井 kn-aut-mei=英夫 aut-affil-num=8 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=9 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=10 en-affil= kn-affil=東京医科歯科大学人類遺伝研究室 END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=11-12 article-no= start-page=607 end-page=613 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19731230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Report of Field Survey on Acatalasemia and Hypocatalasemia in 1970 and 1971 kn-title=昭和45年度および46年度Acatalasemia,Hypocatalasemia調査集計 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authers reported the results of field survey on acatalasemia and hypocatalasemia during the years of 1970 and 1971. Six hypocatalasemias were seen in the tests of 3,593 individuals in several parts of Japan. No acatalasemic individuals were reported since 1968. Consequently, the total of reported acatalasemias were 96 cases of 46 families by the end of 1971. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=高原滋夫 kn-aut-sei=高原 kn-aut-mei=滋夫 aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=2 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=三谷恭夫 kn-aut-sei=三谷 kn-aut-mei=恭夫 aut-affil-num=3 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=笠井英夫 kn-aut-sei=笠井 kn-aut-mei=英夫 aut-affil-num=4 ORCID= en-aut-name=KawasakiKoichiro en-aut-sei=Kawasaki en-aut-mei=Koichiro kn-aut-name=川崎康一郎 kn-aut-sei=川崎 kn-aut-mei=康一郎 aut-affil-num=5 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=6 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=7 en-affil= kn-affil=東京医科歯科大学人類遺伝研究室 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=7-8 article-no= start-page=527 end-page=534 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A report of field survey on acatalasemia and hypocatalasemia in 1972 and 1973 kn-title=昭和47年度および48年度 Acatalasemia, Hypocatalasemia 調査集計 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of field survey on acatalasemia and hypocatalasemia during the year of 1972 and 1973. Seventeen hypocatalasemias were seen in the test of 7,475 individuals at Oahu Is. of Hawaii, U.S.A. Among them two Englishmen, one Portugese and three Filipinos were included. One new acatalasemia case was reported in 1972. Consequently, the total of reported acatalasemias were 97 cases of 47 families by the end of 1973. en-copyright= kn-copyright= en-aut-name=TanakaTohru en-aut-sei=Tanaka en-aut-mei=Tohru kn-aut-name=田中徹 kn-aut-sei=田中 kn-aut-mei=徹 aut-affil-num=1 ORCID= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=高原滋夫 kn-aut-sei=高原 kn-aut-mei=滋夫 aut-affil-num=2 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=3 ORCID= en-aut-name=MasudaYu en-aut-sei=Masuda en-aut-mei=Yu kn-aut-name=増田游 kn-aut-sei=増田 kn-aut-mei=游 aut-affil-num=4 ORCID= en-aut-name=ArakawaKiyoshi en-aut-sei=Arakawa en-aut-mei=Kiyoshi kn-aut-name=荒川清 kn-aut-sei=荒川 kn-aut-mei=清 aut-affil-num=5 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=笠井英夫 kn-aut-sei=笠井 kn-aut-mei=英夫 aut-affil-num=6 ORCID= en-aut-name=TaniWataru en-aut-sei=Tani en-aut-mei=Wataru kn-aut-name=谷互 kn-aut-sei=谷 kn-aut-mei=互 aut-affil-num=7 ORCID= en-aut-name=ShibaKanji en-aut-sei=Shiba en-aut-mei=Kanji kn-aut-name=芝侃司 kn-aut-sei=芝 kn-aut-mei=侃司 aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=9 ORCID= en-aut-name=OkamotoKaneko en-aut-sei=Okamoto en-aut-mei=Kaneko kn-aut-name=岡本かね子 kn-aut-sei=岡本 kn-aut-mei=かね子 aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=9 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=10 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 affil-num=11 en-affil= kn-affil=東京医科歯科大学人類遺伝研空室 END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=3 article-no= start-page=183 end-page=187 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Two programs supporting community dentistry: an oral implant course and education about dysphagia rehabilitation kn-title=地域の歯科医療関係者に対する支援―口腔インプラント講習会と摂食・ 嚥下リハビリテーション教育― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AzumaTetsuji en-aut-sei=Azuma en-aut-mei=Tetsuji kn-aut-name=東哲司 kn-aut-sei=東 kn-aut-mei=哲司 aut-affil-num=1 ORCID= en-aut-name=AriokaKyoko en-aut-sei=Arioka en-aut-mei=Kyoko kn-aut-name=有岡享子 kn-aut-sei=有岡 kn-aut-mei=享子 aut-affil-num=2 ORCID= en-aut-name=ArakawaHikaru en-aut-sei=Arakawa en-aut-mei=Hikaru kn-aut-name=荒川光 kn-aut-sei=荒川 kn-aut-mei=光 aut-affil-num=3 ORCID= en-aut-name=EgusaMasahiko en-aut-sei=Egusa en-aut-mei=Masahiko kn-aut-name=江草正彦 kn-aut-sei=江草 kn-aut-mei=正彦 aut-affil-num=4 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name=窪木拓男 kn-aut-sei=窪木 kn-aut-mei=拓男 aut-affil-num=5 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=森田学 kn-aut-sei=森田 kn-aut-mei=学 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 予防歯科学 affil-num=2 en-affil= kn-affil=岡山大学病院 特殊歯科総合治療部第1総合診療室 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 インプラント再生補綴学 affil-num=4 en-affil= kn-affil=岡山大学病院 特殊歯科総合治療部第1総合診療室 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 インプラント再生補綴学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 予防歯科学 en-keyword=地域支援 kn-keyword=地域支援 en-keyword=口腔インプラント kn-keyword=口腔インプラント en-keyword=摂食 kn-keyword=摂食 en-keyword=嚥下リハビリテーション kn-keyword=嚥下リハビリテーション END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=5-6 article-no= start-page=577 end-page=586 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Field survey of acatalasemia and hypocatalasemia from 1949 through 1985 kn-title=昭和60年までのAcatalasemia,Hypocatalasemia調査集計 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of a field survey of acatalasemia and hypocatalasemia conducted from 1949 through 1985. Six families and eleven cases of acatalasemia and twelve hypocatalasemia cases were added to the statistics reported in 1976. As a result, the total number of reported acatalasemias became 108 cases in 53 families as of the end of 1985. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=高原滋夫 kn-aut-sei=高原 kn-aut-mei=滋夫 aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=2 ORCID= en-aut-name=MasudaYu en-aut-sei=Masuda en-aut-mei=Yu kn-aut-name=増田游 kn-aut-sei=増田 kn-aut-mei=游 aut-affil-num=3 ORCID= en-aut-name=NishiokaKeiko en-aut-sei=Nishioka en-aut-mei=Keiko kn-aut-name=西岡慶子 kn-aut-sei=西岡 kn-aut-mei=慶子 aut-affil-num=4 ORCID= en-aut-name=NishizakiKazunori en-aut-sei=Nishizaki en-aut-mei=Kazunori kn-aut-name=西崎和則 kn-aut-sei=西崎 kn-aut-mei=和則 aut-affil-num=5 ORCID= en-aut-name=SugiuraTomoaki en-aut-sei=Sugiura en-aut-mei=Tomoaki kn-aut-name=杉浦友昭 kn-aut-sei=杉浦 kn-aut-mei=友昭 aut-affil-num=6 ORCID= en-aut-name=FurukawaKatsuro en-aut-sei=Furukawa en-aut-mei=Katsuro kn-aut-name=古川勝朗 kn-aut-sei=古川 kn-aut-mei=勝朗 aut-affil-num=7 ORCID= en-aut-name=MizukoYukio en-aut-sei=Mizuko en-aut-mei=Yukio kn-aut-name=水河幸夫 kn-aut-sei=水河 kn-aut-mei=幸夫 aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=9 ORCID= en-aut-name=OgataMasana en-aut-sei=Ogata en-aut-mei=Masana kn-aut-name=緒方正名 kn-aut-sei=緒方 kn-aut-mei=正名 aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部公衆衛生学教室 affil-num=11 en-affil= kn-affil=東京医科歯科大学難治疾患研究所人類遺伝学部門 END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=1-2 article-no= start-page=1 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of L-azetidine-2-carboxylic acid on (3)H-proline uptake into rat incisor dentin kn-title=ラット切歯象牙質における(3)H-prolineの取り込みに及ぼすL-azetidine-2-carboxylic acidの影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the present study the effect of L-azetidine-2-carboxylic acid on uptake of (3)H-proline into incisor dentin of young rats is investigated. For the experiment, (3)H-proline (50mCi/g) and L-azetidine-2-carboxylic acid (1mg/g) were simultaneously injected into rats. The first rat was killed 10min, the second one 30min, the third one 1hr, the fourth one 6hr, and the last one 24hr after the injection. The upper and lower incisors were used for light and electron microscopic autoradiography. In the control, the same procedure was performed but with an injection of 50mCi/g of (3)H-proline only. Quantitative analysis of (3)H-proline incorporation into dentin and pulp of the upper incisors was done and radioactivity was counted by a liquid scintillation-counter. In the control group, at 10 and 30min after the injection, grains were found in odontoblasts. At 1 and 6hr after the injection, they were distributed in the predentin, and the grains were in the dentin 24hr after the injection. In the treated group, on the other hand, grains were found in odontoblasts at 30min and 6hr. Moreover, the grains in the treated group were distributed rather sparsely. The result of the quantitative analysis by a liquid scintillation-counter indicated that the amount of (3)H-proline incorporated into dentin in the treated group was about one third of that in the control. No significant difference was found in the pulps between the treated and the control animals. en-copyright= kn-copyright= en-aut-name=NagaiHiroshi en-aut-sei=Nagai en-aut-mei=Hiroshi kn-aut-name=永井廣 kn-aut-sei=永井 kn-aut-mei=廣 aut-affil-num=1 ORCID= en-aut-name=SuzukiKazunori en-aut-sei=Suzuki en-aut-mei=Kazunori kn-aut-name=鈴木一憲 kn-aut-sei=鈴木 kn-aut-mei=一憲 aut-affil-num=2 ORCID= en-aut-name=SudoHiroko en-aut-sei=Sudo en-aut-mei=Hiroko kn-aut-name=須藤博子 kn-aut-sei=須藤 kn-aut-mei=博子 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学歯学部口腔解剖学第1講座 affil-num=2 en-affil= kn-affil=岡山大学歯学部口腔解剖学第1講座 affil-num=3 en-affil= kn-affil=東北歯科大学口腔解剖学第2講座 en-keyword=切歯象牙質 kn-keyword=切歯象牙質 en-keyword=オートラジオグラフィー kn-keyword=オートラジオグラフィー en-keyword=proline analogue kn-keyword=proline analogue END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=2 article-no= start-page=121 end-page=129 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=現像温度および時間のマンモフイルム特性に与える影響 kn-title=The Influence of Film Processing Temperature and Time on Mammographic film Characteristics en-subtitle= kn-subtitle= en-abstract=フィルム処理条件において,現像温度と処理時間に対する影響を4種類のマンモグラフィ用フィルムKonica New CM, Fuji UM-MA HC,Kodak Min-R M,迅速処理用Kodak EB/RAについて調べた。そして,比較基準用として両面乳剤フィルムFuji UR-2を用いた。感光計で露光したフィルムを現像温度28~36℃,処理時間45~210秒で処理した。特性曲線から得られたフィルム特性(平均階調度,相対感度,カブリ濃度)を異なる現像温度,現像時間に対して評価した。UR-2はほとんど影響を受けず,マンモグラフィ用フィルムは,カブリ濃度が上昇することなく,現像条件の影響を大きく受けた。New CM, UM-MA HC,Min-R Mは現像温度の上昇,処理時間の延長に伴い,平均階調度と相対感度は増加した。しかし,New CM, UM-MA HCの36℃,210秒で増加は限度に達した。EB/RAの平均階調度は一定で,相対感度は両面乳剤フイルムと同 様にわずかな増加であった。これらの結果は,New CM, UM-MA HC, Min-R Mにおいて,処理条件を変化させることにより,被曝低減,コントラスト向上に貢献できる可能性を示唆していた。 kn-abstract=The influence for developing temperature and processing time within film processing conditions was investigated using four mammographic films, Konica New CM, Fuji UM-MA HC, Kodak Min-R M and Kodak EB/RA (for rapid system). And Fuji UR-2, a double-emulsion film, was used as a control. Those sensitometric strips exposed by a sensitometer were processed in the different combinations of developing temperatures ranging from 28 to 36℃, processing times from 45 to 210 sec. Average gradient, relative speed and base plus fog obtained from the measured film characteristic curves were evaluated for the different developing temperatures and times. Fuji UR-2 was scarcely affected and mammographic films were greatly affected in the different combinations without an increase in base plus fog except EB/RA. In New CM, UM-MA HC and Min-R M, the average gradients and the relative speeds increased as the developing temperature was higher and the developing time was longer, but the increases were limit on the combination of 36℃ and 210 sec in New CM and UM-MA HC. In EB/RA, the average gradients were almost constant and the relative speeds increased slightly like the double-emulsion film. These results suggested that it would be possible to contribute to dose reduction and advancement of contrast in New CM, UM-MA HC and Min-R M by changing these processing parameters. en-copyright= kn-copyright= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=1 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=3 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=4 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=竹内知行 kn-aut-sei=竹内 kn-aut-mei=知行 aut-affil-num=7 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=本田貢 kn-aut-sei=本田 kn-aut-mei=貢 aut-affil-num=8 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=吉田彰 kn-aut-sei=吉田 kn-aut-mei=彰 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=9 en-affil= kn-affil=広島県立保健福祉短期大学放射線技術科学科 en-keyword=マンモグラフィ (Mammography) kn-keyword=マンモグラフィ (Mammography) en-keyword=現像処理パラメータ (Processing Parameter) kn-keyword=現像処理パラメータ (Processing Parameter) en-keyword=特性曲線 (Characteristic Curve) kn-keyword=特性曲線 (Characteristic Curve) en-keyword=平均階調度 (Average Gradient) kn-keyword=平均階調度 (Average Gradient) en-keyword=相対感度 (Relative Speed) kn-keyword=相対感度 (Relative Speed) END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=2 article-no= start-page=113 end-page=119 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Examination of density and mixing ratio of barium preparations, using an originally created phantom kn-title=自作ファントムによる硫酸バリウム製剤の濃度及び混合比の検討 en-subtitle= kn-subtitle= en-abstract=A phantom copied designs of coins was created with alginate dental impression material to establish a objective, simple and easy method for deciding density of barium sulfate suspensions which are used for stomach X-ray examination as contrast media. As a result of examining proper density (PD) of two kind of barium preparations with this phantom, in case of BARITOP P and BARICON MEAL, PD were almost shown by the next equation : PD(W/V%)=0.75C+165(C meant content of BARICON MEAL (%)). As BARICON MEAL resulted in hight contrast, it was thought to be suitable for a close examination. Mixture of BARITOP P and BARICON MEAL was thought to be suited to a routine examination becouse of wide permissible level of density. This phantom would be able to apply to the test of balium preparations, X-ray TV systems, screen/film systems and so on. kn-abstract=胃Ⅹ線検査に造影剤として用いられる硫酸バリウム懸濁液の濃度を,簡便に,客観的に決定する目的で,歯科用アルギン酸塩印象材を用いて,コインの図柄を写しとったファントムを制作した。これを使って二種類の硫酸バリウム製剤の適正濃度(PD)を調べた結果,BARITOP PとBARICON MEALを単体,若くは混合した場合には,おおよそ,PD(W/V%)=0.75C+165(ただし,CはBARICON MEALの混合比(%))となった。また,BARICON MEALはコントラストが高く,精密検査に有利だと考えられ,BARITOP PとBARICON MEALを混合すると濃度の許容範囲が広がるため,通常の検査に都合がよいと考えられた。更に,このファントムは簡便に作成することができ,しかも,硫酸バリウム懸濁 液との親和性も良いことから,硫酸バリウム製剤やⅩ線TV装置の評価,増感紙・フィルム系の評価等にも応用できると考えられた。 en-copyright= kn-copyright= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=1 ORCID= en-aut-name=MiyaharaTomonori en-aut-sei=Miyahara en-aut-mei=Tomonori kn-aut-name=宮原智則 kn-aut-sei=宮原 kn-aut-mei=智則 aut-affil-num=2 ORCID= en-aut-name=SumiKazuyuki en-aut-sei=Sumi en-aut-mei=Kazuyuki kn-aut-name=鷲見和幸 kn-aut-sei=鷲見 kn-aut-mei=和幸 aut-affil-num=3 ORCID= en-aut-name=OkuraYasuhiko en-aut-sei=Okura en-aut-mei=Yasuhiko kn-aut-name=大倉保彦 kn-aut-sei=大倉 kn-aut-mei=保彦 aut-affil-num=4 ORCID= en-aut-name=MiyakeKoichi en-aut-sei=Miyake en-aut-mei=Koichi kn-aut-name=三宅浩一 kn-aut-sei=三宅 kn-aut-mei=浩一 aut-affil-num=5 ORCID= en-aut-name=OkudaKazuhiro en-aut-sei=Okuda en-aut-mei=Kazuhiro kn-aut-name=奥田和裕 kn-aut-sei=奥田 kn-aut-mei=和裕 aut-affil-num=6 ORCID= en-aut-name=TandaniNobuyoshi en-aut-sei=Tandani en-aut-mei=Nobuyoshi kn-aut-name=丹谷延義 kn-aut-sei=丹谷 kn-aut-mei=延義 aut-affil-num=7 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=8 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=9 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=10 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=11 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=12 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=3 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=4 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=5 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=6 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=7 en-affil= kn-affil=(財)倉敷成人病センター放射線部 affil-num=8 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=9 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=10 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=11 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=12 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=造影剤 (contrast media) kn-keyword=造影剤 (contrast media) en-keyword=硫酸バリウム (barium sulfate suspension) kn-keyword=硫酸バリウム (barium sulfate suspension) en-keyword=胃X線検査 (X-ray examination of the stomach) kn-keyword=胃X線検査 (X-ray examination of the stomach) en-keyword=アルギン酸塩印象材 (alginate impression material) kn-keyword=アルギン酸塩印象材 (alginate impression material) en-keyword=ファントム (phantom) kn-keyword=ファントム (phantom) END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue=2 article-no= start-page=75 end-page=81 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relative biological effectiveness (RBE) and potential leathal damage repair (PLDR) of heavy-ion beam kn-title=重粒子線の生物学的効果比と潜在性致死損傷からの回復 en-subtitle= kn-subtitle= en-abstract=Relative biological effectiveness (RBE) and repair of potential lethal damage (PLDR) of NIH3T3 cells against heavy-ion radiation were studied. RBE of 150 KV X-rays and neutron estimated from LD(10) dose of dose response survival curves compared to (60)Co γ-ray were 1.26 and 2.44, respectively. RBE of 13, 20, 50, 90, 140, 150, 153, 200 keV/μm of LET of carbon beam were 1.41, 1.47, 2.22, 2.61, 2.61, 1.61, 2.05 and 1.57, respectively. Potential lethal damage repair (PLDR) after exposure to carbon beam was observed. The magnitude of PLDR of (60)Co γ-ray was the biggest. As for the carbon beam of LET of 13 keV/μm as well, PLDR were observed. PLDR decreased when LET of carbon beam grew big. kn-abstract=150KV X線,中性子線及び炭素(LET13, 20, 50, 90, 140, 150, 153, 200keV/μm)を照射したマウスNIH3T3細胞の生存率曲線のLD(10)から(60)Coγ線に対する生物学的効果比(RBE)を求めた。RBEは150KV X線では1.26,中性子線では2.44,炭素線(LET13, 20, 50, 90, 140, 150, 153, 200keV/μm)ではそれぞれ1.41, 1.47, 2.22, 2.61, 1.61, 2.05, 1.57であった。LETとRBEの関係では100keV/μm付近にピークを認めた。150KVX線のLETは13keV/μm,中性子線のLETは70keVμmに相当した。(60)Co γ線の潜在性致死損傷からの回復(PLDR)は大きかった。炭素線(13keV/μm)照射でもPLDRが観察されるがLETが大きくなるとPLDRは減少したが,LET90keV/μmの炭素線でもPLDRが認められた。照射時の細胞状態の検討では増殖期の細胞の感受性は定常期細胞に比し僅かに高かった。 en-copyright= kn-copyright= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=川崎祥二 kn-aut-sei=川崎 kn-aut-mei=祥二 aut-affil-num=1 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=澁谷光一 kn-aut-sei=澁谷 kn-aut-mei=光一 aut-affil-num=2 ORCID= en-aut-name=AsaumiJunichi en-aut-sei=Asaumi en-aut-mei=Junichi kn-aut-name=浅海淳一 kn-aut-sei=浅海 kn-aut-mei=淳一 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小松めぐみ kn-aut-sei=小松 kn-aut-mei=めぐみ aut-affil-num=4 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=6 ORCID= en-aut-name=FurusawaYoshiya en-aut-sei=Furusawa en-aut-mei=Yoshiya kn-aut-name=古澤佳也 kn-aut-sei=古澤 kn-aut-mei=佳也 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学歯学部歯科放射線学講座 affil-num=4 en-affil= kn-affil=岡山大学医学部医学科放射線医学講座 affil-num=5 en-affil= kn-affil=岡山大学医学部医学科放射線医学講座 affil-num=6 en-affil= kn-affil=岡山大学医学部医学科放射線医学講座 affil-num=7 en-affil= kn-affil=放射線医学研究所宇宙粒子線研究グループ en-keyword=PLDR kn-keyword=PLDR en-keyword=RBE kn-keyword=RBE en-keyword=Heavy-lon Radiation kn-keyword=Heavy-lon Radiation en-keyword=NIH3T3 Cells kn-keyword=NIH3T3 Cells END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=2 article-no= start-page=107 end-page=117 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=マイクロコントローラを組み込んだ歯科インプラント動揺測定装置の開発 kn-title=Development of a microcontroller-based dental implant movement checker en-subtitle= kn-subtitle= en-abstract=本研究の目的は歯科インプラントの動揺を簡易に測定できる装置の開発である。本装置では測定プローブで一定振幅の周波数を歯科インプラントに与え、その加速度信号を検出する。そして本研究で考察した評価基準に基づいてIM値を表示する。さらにRigolac®やMolteno®を用い、インプラント体の長さおよび直径を変えたインプラントモデルを作製した。400Hzにおけるモデルの機械モビリティとIM値との間には、よい相関が見られた(R(2)=0.92)。IMチェッカーを用い、一人の測定者が行った12回の測定において、インプラントの動揺を判別することが可能であった(P<0.01)。また4人の測定者による測定では,その平均値に対し測定者間の有意差は見られなかった(P<0.01)。従ってIMチェッカーは十分な信頼性を有し、歯科臨床に有効であると考える。 kn-abstract=The aim of this study was to develop a portable device (IM checker) for measuring dental implant mobility using a microcontroller. A constant amplitude and frequency vibration was applied to a dental implant model and the acceleration signal was detected using measuring probe. Then the IM score was obtained using the criteria developed in this study. We made several implant models of different implant lengths, diameters and material of Rigolac® or Molteno®. There was a linear relationship between mechanical mobility at 400 Hz of the models and the IM scores (R(2) = 0.92). The IM checker could discriminate the mobility of dental implant models in twelve measurements with P < 0.01. There was no significant difference in the means of the IM score measured by four operators with P < 0.01. The results indicated that the IM checker had sufficient reliability and could be available in dental clinics. en-copyright= kn-copyright= en-aut-name=Kusuma WijayaSastra en-aut-sei=Kusuma Wijaya en-aut-mei=Sastra kn-aut-name=クスマ ウイジャヤサストラ kn-aut-sei=クスマ ウイジャヤ kn-aut-mei=サストラ aut-affil-num=1 ORCID= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=2 ORCID= en-aut-name=SarataniKeiji en-aut-sei=Saratani en-aut-mei=Keiji kn-aut-name=更谷啓治 kn-aut-sei=更谷 kn-aut-mei=啓治 aut-affil-num=3 ORCID= en-aut-name=MatsutaniYoshio en-aut-sei=Matsutani en-aut-mei=Yoshio kn-aut-name=松谷善雄 kn-aut-sei=松谷 kn-aut-mei=善雄 aut-affil-num=4 ORCID= en-aut-name=TatsutaMitsuhiro en-aut-sei=Tatsuta en-aut-mei=Mitsuhiro kn-aut-name=龍田光弘 kn-aut-sei=龍田 kn-aut-mei=光弘 aut-affil-num=5 ORCID= en-aut-name=KawazoeTakayoshi en-aut-sei=Kawazoe en-aut-mei=Takayoshi kn-aut-name=川添堯彬 kn-aut-sei=川添 kn-aut-mei=堯彬 aut-affil-num=6 ORCID= en-aut-name=KojimaHideki en-aut-sei=Kojima en-aut-mei=Hideki kn-aut-name=小嶋英幹 kn-aut-sei=小嶋 kn-aut-mei=英幹 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=3 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 affil-num=4 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 affil-num=5 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 affil-num=6 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 affil-num=7 en-affil= kn-affil=隆祥産業株式会社生産本部技術部 en-keyword=Tooth mobility (歯の動揺) kn-keyword=Tooth mobility (歯の動揺) en-keyword=mechanical mobility (機械モビリティ) kn-keyword=mechanical mobility (機械モビリティ) en-keyword=dental implant (インプラント) kn-keyword=dental implant (インプラント) en-keyword=manual examination (触診) kn-keyword=manual examination (触診) END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=2 article-no= start-page=101 end-page=106 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=加温後のtsAF8細胞の細胞周期 kn-title=Cell cycle of tsAF8 after heating en-subtitle= kn-subtitle= en-abstract=tsAF8細胞は45℃の加温後34℃で培養すると温熱耐性が速やかに発現するが,加温後,制限温度である39.7℃で培養すると温熱耐性の発現が抑制される。加温後の培養温度が細胞周期に影響し,その結果として温熱耐性発現に影響を与えている可能性があることから,今回,Propidium Iodide(PI)とbromodeoxyuridine(BrdU)でtsAF8細胞を二重染色し,フローサイトメトリーによって温熱耐性と細胞周期の関係の有無について調べた。tsAF8細胞を45℃20分の加温後34℃で培養すると,6時間後にはG(1)期の細胞が減少し,12時間後にはG(2)/M期への蓄積が見られた。しかし,加温後39.7℃で培養した場合には細胞周期の進行がほとんど見られなかった。BrdU の取込みは,加温せずに39.7℃で培養した場合には活発に行われ,また,45℃20分加温後34℃で培養した場合には,6時間後にはBrdUの取り込みは65.1%まで回復した。しかし,温熱耐性発現の抑制が観察される45℃20分加温後39.7℃で培養した場合には,BrdUの取込み量は6時間後に一時的に15.1%に回復するが,12時間後には取込み量はゼロとなった。BrdUの取り込みが阻害されたのはstep-down heatingの現象による細胞生存率の減少が原因だと考えられたが,温熱耐性発現の抑制が観察される条件下では細胞周期の特定の時期への集積がなかったことから,温熱耐性と細胞周期との関係はtsAF8細胞においては見い出されなかった。 kn-abstract=Thermotolerance in tsAF8 cells develops during incubation at 34℃ after heating at 45℃, while it is suppressed by the following incubation at a non-permissive temperature of 39.7℃ after the same heating. The incubation temperature after heating may affect the cell cycle and consequently thermotolerance. In the present study, a relationship between the thermotolerance and the cell cycle of tsAF8 was investigated. The cell cycle fractions and DNA synthesis were measured by flow cytometry using double staining with propidium iodide and bromodeoxyuridine. When the tsAF8 cells were heated at 45℃ for 20 min, and thereafter incubated at 34℃, bromodeoxyuridine uptake in the S phase cells (DNA synthesis) was recovered to 65.1% 6 h after the heating, and the cells showed gradual accumulation in the G(2)/M phase. When the cells were incubated at 39.7℃ after heating at 45℃ for 20 min, then showed inhibition of thermotolerance development, the DNA synthesis was recovered to 15.1% temporarily 6 h after the heating, but it became 0% after 12 h, and the cells did not remarkably accumulate in any phases of the cell cycle. This inhibition of DNA synthesis at 39.7℃ was considered to be the result of cell survival decreasing by a step-down heating. However, the relationship between the thermotolerance and the cell cycle was not found out in tsAF8 cells, because the cells did not accumulate in any phases of the cell cycle under the inhibitory condition of thermotolerance. en-copyright= kn-copyright= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=澁谷光一 kn-aut-sei=澁谷 kn-aut-mei=光一 aut-affil-num=1 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=川崎祥二 kn-aut-sei=川崎 kn-aut-mei=祥二 aut-affil-num=2 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=3 ORCID= en-aut-name=AsaumiJun-ichi en-aut-sei=Asaumi en-aut-mei=Jun-ichi kn-aut-name=浅海淳一 kn-aut-sei=浅海 kn-aut-mei=淳一 aut-affil-num=4 ORCID= en-aut-name=KatoHirokazu en-aut-sei=Kato en-aut-mei=Hirokazu kn-aut-name=加藤博和 kn-aut-sei=加藤 kn-aut-mei=博和 aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院放射線科 affil-num=4 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=5 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院放射線科 en-keyword=thermotolerance (温熱耐性) kn-keyword=thermotolerance (温熱耐性) en-keyword=hyperthermia (ハイパーサーミア) kn-keyword=hyperthermia (ハイパーサーミア) en-keyword=tsAF8 kn-keyword=tsAF8 en-keyword=cell cycle (細胞周期) kn-keyword=cell cycle (細胞周期) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=9 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20041215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol in the rat kn-title=はとむぎ,はとむぎテンペのラットコレステロール代謝改善作用に関する研究 en-subtitle= kn-subtitle= en-abstract=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol fractions was examined in the rat. Twelve-week-old male Sprague-Dawley rats were received commercial MF meal (control group), Coicis semen-containing MF meal (Coicis semen group), or tempeh-containing MF meal (tempeh group). Cholesterol fractions were analyzed by high performance liquid chromatography at the start of experiment, and 2, 6, 18 weeks later. No difference was found in body weight nor total cholesterol among the three groups. LDL cholesterol was significantly lowered in the tempeh group at 2, 6, 18 weeks. LDL cholesterol/HDL cholesterol ratio also decreased at 2 and 18 weeks. In the both Coicis semen- and tempeh-fooded groups, LDL cholesterol and LDL cholesterol/HDL cholesterol ratio were lower than the control group although they were not statistically significant. No difference was found in HDL cholesterol among the three groups. The results suggest that tempeh may have a favorable effect on cholesterol metabolism. kn-abstract=はとむぎ(Coicis semen)をテンペ菌(Rhizopus oligosporus)で発酵したはとむぎテンペ(テンペ)の血清コレステロール代謝に対する作用を検討した。生後12週齢のSprague-Dawley系雄ラットに市販固形飼料(コントロール群),はとむぎ混合飼料(はとむぎ群),テンペ混合飼料(テンペ群)を投与し,2,6,18週間後に高速液体クロマトグラフィー法で血清コレステロールを測定した。体重増加,総コレステロールはいずれの時点でも3群間に差がなかったが,テンペ群では投与前と比較して2,6,18週間後にLDLコレステロールが有意に低下し,LDLコレステロール/HDLコレステロール比も2,18週間後に有意に低下した。テンペ群はコントロール群と比較してもLDLコレステロールとLDLコレステロール/HDLコレステロール比が低く,はとむぎ群でも低い傾向がみられたが,有意差はなかった。以上から,テンペがコレステロール代謝改善作用をもつことが示唆された。 en-copyright= kn-copyright= en-aut-name=OkamotoMotoi en-aut-sei=Okamoto en-aut-mei=Motoi kn-aut-name=岡本基 kn-aut-sei=岡本 kn-aut-mei=基 aut-affil-num=1 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name=臼井真一 kn-aut-sei=臼井 kn-aut-mei=真一 aut-affil-num=2 ORCID= en-aut-name=OkazakiMitsuyo en-aut-sei=Okazaki en-aut-mei=Mitsuyo kn-aut-name=岡崎三代 kn-aut-sei=岡崎 kn-aut-mei=三代 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=3 en-affil= kn-affil=東京医科歯科大学教養部 en-keyword=はとむぎ (Coicis semen) kn-keyword=はとむぎ (Coicis semen) en-keyword=はとむぎテンペ (Rhizopus oligosporus, tempeh) kn-keyword=はとむぎテンペ (Rhizopus oligosporus, tempeh) en-keyword=コレステロール (cholesterol) kn-keyword=コレステロール (cholesterol) en-keyword=ラット (rat) kn-keyword=ラット (rat) END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=1 article-no= start-page=35 end-page=40 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Supporting female physicians in career development : Activity report on MEXT-supported projects and our future plans kn-title=女性医師のキャリア支援 H19文部科学省社会的ニーズに対応した質の高い医療人養成推進プログラム(医療人 GP)選定 「女性を生かすキャリア支援計画」の活動報告と今後 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KataokaHitomi en-aut-sei=Kataoka en-aut-mei=Hitomi kn-aut-name=片岡仁美 kn-aut-sei=片岡 kn-aut-mei=仁美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部・歯学部病院 卒後臨床研修センター,キャリアセンター(医療人 GP 事務局) en-keyword=女性医師 kn-keyword=女性医師 en-keyword=キャリア kn-keyword=キャリア en-keyword=復職支援 kn-keyword=復職支援 en-keyword=シミュレーショントレーニング kn-keyword=シミュレーショントレーニング en-keyword=屋根瓦式サポート kn-keyword=屋根瓦式サポート END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=4-5 article-no= start-page=513 end-page=519 dt-received= dt-revised= dt-accepted= dt-pub-year=1966 dt-pub=19660530 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=琉球宮古群島における小中学校学童の医学的調査について en-subtitle= kn-subtitle= en-abstract= kn-abstract=An expedition was performed on Miyako Is., Ryukyu, carrying out medical examinations on school-children in May and June, 1965. The investigations consisted of screening tests for acatalasemic gene carriers and ENT examinations. Results obtained are as follows: 1. ENT examinations; morbidity to ear diseases of Miyako children was higher than that of Japan proper. On the contrary morbidity to nose and throat diseases of Miyako was lower than Japan Proper. 2. Screening tests; only one hypocatalasemic boy was found out among 10, 083 children examined. Then emergence of hypocatalasemia on Miyako Is. was 0.01%, one tenth of already known Japanese mean value. en-copyright= kn-copyright= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=小倉義郎 kn-aut-sei=小倉 kn-aut-mei=義郎 aut-affil-num=1 ORCID= en-aut-name=KoyamaTakashi en-aut-sei=Koyama en-aut-mei=Takashi kn-aut-name=小山高司 kn-aut-sei=小山 kn-aut-mei=高司 aut-affil-num=2 ORCID= en-aut-name=HoriFumio en-aut-sei=Hori en-aut-mei=Fumio kn-aut-name=堀典雄 kn-aut-sei=堀 kn-aut-mei=典雄 aut-affil-num=3 ORCID= en-aut-name=SumidaShozo en-aut-sei=Sumida en-aut-mei=Shozo kn-aut-name=住田昭三 kn-aut-sei=住田 kn-aut-mei=昭三 aut-affil-num=4 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=三谷恭夫 kn-aut-sei=三谷 kn-aut-mei=恭夫 aut-affil-num=5 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=黒田泰生 kn-aut-sei=黒田 kn-aut-mei=泰生 aut-affil-num=6 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=大倉興司 kn-aut-sei=大倉 kn-aut-mei=興司 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科学教室 affil-num=7 en-affil= kn-affil=東京医科歯科大学人類遺伝学研究室 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=447 end-page=454 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Free radicals, superoxide dismutase activity and lipid peroxides in gingiva of ODU plaque-susceptible rats kn-title=歯肉炎自然発症ラットの歯肉炎発症におけるフリーラジカルの関与に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Free radicals, superoxide dismutase activity and lipid peroxides in the gingiva of Dental University (ODU) plaque-susceptible (Sus) rats were estimated at the ages of 1,2,3,4,5,7 and 8 months, and were compared with those of control Wistar-kyoto rats. Low levels of hydroxyl radicals were noted in the anterior and posterior gingiva of ODU Sus rats at 2 and 5 month, but significantly increased in the anterior gingiva at 4 and 7 months and in the anterior and posterior gingiva at 7 and 8 months, compared to those of control rats. Levels of carbon centered radicals were significantly higher in the anterior gingiva at 2 months and in both the anterior and posterior gingiva at 3 months. Superoxide dismutase activities were accelerated significantly at 2,4 and 5 months, and then were reduced at 8 months in the anterior gingiva. Otherwise, they were at low levels in the posterior gingiva at 1 and 2 months, were accelerated at 3 and 4 months, and reduced again at 7 and 8 months. Thiobarbituric acid reactive substances decreased transitorily at 7 months in both the anterior and posterior. These experimental results suggest that free radicals may be related to the pathogenesis and development of gingivitis in plaque susceptible ODU Sus rats. en-copyright= kn-copyright= en-aut-name=SatohKazuyoshi en-aut-sei=Satoh en-aut-mei=Kazuyoshi kn-aut-name=佐藤和良 kn-aut-sei=佐藤 kn-aut-mei=和良 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属分子細胞医学研究施設神経情報学部門 en-keyword=歯肉炎自然発症ラット kn-keyword=歯肉炎自然発症ラット en-keyword=フリーラジカル kn-keyword=フリーラジカル en-keyword=活性酸素 kn-keyword=活性酸素 en-keyword=過酸化脂質 kn-keyword=過酸化脂質 en-keyword=スーパーオキシドジムスターゼ活性 kn-keyword=スーパーオキシドジムスターゼ活性 END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue=3 article-no= start-page=299 end-page=305 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20081201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The collaborative role of oral surgery with plastic as well as head & neck surgery in head and neck cancers : Preoperative plate-bending method in cases with mandibular reconstruction using plaster 3D models kn-title=頭頸部癌における頭頸部外科,形成外科,口腔外科3科合同手術における口腔外科の役割:下顎再建症例における3D石膏造形モデルを利用した術前プレート屈曲法 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The collaboration of various medical teams is crucial for the appropriate treatment of cancer patients. However, in Japan, it is very difficult for oral surgeons to cooperate with head and neck surgeons due to conflicts in the treatment of those patients. There have been few studies on this subject. In the current work, we report on the collaboration of head and neck surgeons, plastic surgeons and oral surgeons in operations on two patients with gingival carcinomas in the mandible. We first prepared plaster 3D models of the patients'mouths by means of ink-jet from CT data. We pre-bent the reconstruction plates using the preoperative 3D models. Therefore, we could save the time required to bend the plate. Plaster models are cheaper than resin models. It is also easy to model the surgery using the plate. During the operation, head and neck surgeons resected the tumors, plastic surgeons performed reconstruction with vascularized bone or skin graft, and oral surgeons (dentists) did plate fixation and took charge of the patients'occlusion. This method resulted in patients having good occlusion after the operation. en-copyright= kn-copyright= en-aut-name=MizukawaNobuyoshi en-aut-sei=Mizukawa en-aut-mei=Nobuyoshi kn-aut-name=水川展吉 kn-aut-sei=水川 kn-aut-mei=展吉 aut-affil-num=1 ORCID= en-aut-name=TominagaSusumu en-aut-sei=Tominaga en-aut-mei=Susumu kn-aut-name=冨永進 kn-aut-sei=冨永 kn-aut-mei=進 aut-affil-num=2 ORCID= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=木股敬裕 kn-aut-sei=木股 kn-aut-mei=敬裕 aut-affil-num=3 ORCID= en-aut-name=OnodaTomoo en-aut-sei=Onoda en-aut-mei=Tomoo kn-aut-name=小野田友男 kn-aut-sei=小野田 kn-aut-mei=友男 aut-affil-num=4 ORCID= en-aut-name=SugiyamaNarushi en-aut-sei=Sugiyama en-aut-mei=Narushi kn-aut-name=杉山成史 kn-aut-sei=杉山 kn-aut-mei=成史 aut-affil-num=5 ORCID= en-aut-name=YamachikaEiki en-aut-sei=Yamachika en-aut-mei=Eiki kn-aut-name=山近英樹 kn-aut-sei=山近 kn-aut-mei=英樹 aut-affil-num=6 ORCID= en-aut-name=YamadaYousuke en-aut-sei=Yamada en-aut-mei=Yousuke kn-aut-name=山田庸介 kn-aut-sei=山田 kn-aut-mei=庸介 aut-affil-num=7 ORCID= en-aut-name=KimuraTakuji en-aut-sei=Kimura en-aut-mei=Takuji kn-aut-name=木村卓爾 kn-aut-sei=木村 kn-aut-mei=卓爾 aut-affil-num=8 ORCID= en-aut-name=TakeuchiTetsuo en-aut-sei=Takeuchi en-aut-mei=Tetsuo kn-aut-name=竹内哲男 kn-aut-sei=竹内 kn-aut-mei=哲男 aut-affil-num=9 ORCID= en-aut-name=UenoTakaaki en-aut-sei=Ueno en-aut-mei=Takaaki kn-aut-name=植野高章 kn-aut-sei=植野 kn-aut-mei=高章 aut-affil-num=10 ORCID= en-aut-name=TakagiShin en-aut-sei=Takagi en-aut-mei=Shin kn-aut-name=高木慎 kn-aut-sei=高木 kn-aut-mei=慎 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 口腔外科再建系 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 耳鼻咽喉・頭頸部外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 形成再建外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 耳鼻咽喉・頭頸部外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 形成再建外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 顎口腔再建外科学 affil-num=7 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 口腔外科病態系 affil-num=8 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 口腔外科病態系 affil-num=9 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 医療技術部歯科系部門技工室 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 顎口腔再建外科学 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 顎口腔再建外科学 en-keyword=チーム医療 (medical team approach) kn-keyword=チーム医療 (medical team approach) en-keyword=頭頸部癌 (head and neck carcinoma) kn-keyword=頭頸部癌 (head and neck carcinoma) en-keyword=3D石膏モデル (plaster 3D model) kn-keyword=3D石膏モデル (plaster 3D model) en-keyword=インクジェット法 (ink-jet method) kn-keyword=インクジェット法 (ink-jet method) en-keyword=下顎再建 (mandibular reconstruction) kn-keyword=下顎再建 (mandibular reconstruction) END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=51 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cross-sectional study of dietary habits and dental caries among senior high school students kn-title=高校生における食習慣と齲蝕発生における横断的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three hundred fifty-nine senior high school students were examined for dental caries and dietary habits and the findings were subjected to mono- and multivariate analyses. Dental caries were higher in female students and differed between the anterior teeth and molars. In female students, frequently eating potatoes and having increased dental caries showed a significantly higher odds ratio. On multivariate analysis, a mixed group of male and female students showed high odds ratios for bread, fruit and dairy products. These results indicate that modernization of dietary habits is closely associated with dental caries in adults. en-copyright= kn-copyright= en-aut-name=TakaharaMasahiko en-aut-sei=Takahara en-aut-mei=Masahiko kn-aut-name=髙原雅彦 kn-aut-sei=髙原 kn-aut-mei=雅彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 en-keyword=齲蝕 kn-keyword=齲蝕 en-keyword=食習慣 kn-keyword=食習慣 en-keyword=横断研究 kn-keyword=横断研究 en-keyword=多変量解析 kn-keyword=多変量解析 END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=3-8 article-no= start-page=47 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on factors relating to oral malodor and preventive measures among the elderly kn-title=要介護高齢者における口臭とその関連要因及び予防対策に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=One hundred ten elderly with disabilities in institutions or receiving home care were selected and informed. This study focused on oral malodor and discusses consent was obtained the relationship between oral malodor and the state of dental health and oral hygiene in the elderly with disabilities. ADL of the elderly with disabilities (rank J, A, B, C, settled by National Health Administration in Japan) were 8.2% at rank J, 28.2% at rank A, 42.7% at rank B and 20.9% at rank C, respectively. The incident rate of swallowing pneumonitis, fever and bedsores were low. Accordingly, physical and mental conditions were comparatively preferable. Tooth and periodontal conditions were comparablye to nationwide results. 1. The elderly in poor ADL had marked oral malodor compared with those in good health. 2. The elderly who required assistance to eat or had special dietary requirements had marked oral malodor. 3. The elderly who had normal oral functions and the ability to take care of their own oral hygiene had markedly less oral malodor. 4. The elderly who had poor oral hygiene exhibitings thick tongue coating and positive results in a Candida albicans culture test, had marked oral malodor. 5. Using, the multivariate statistical analysis of Hayashi methodsⅡ, the coefficient of correlation between the state of oral malodor and 27 variables was obtained. 1) The study obtained trustworthy values that discriminate analysis 92.7% and correlation ratio is 0.53. 2) The variables related to severe oral malodor, extracted by the multivariate statistical analysis in descending order, were: "low level of ADL in gargling and denture brushing", "cigarette smoking", "speech disabilities", "unsatisfactory mastication", "need for special dietary care", "oral druyness", "gingivitis", "soft diet of side dish", "living in a special institution caring for the elderly", "thick tongue coating", and "a positive Candida albicans culture test", respectively. 3) The items related with comparatively comfortable or bearable oral malodor, extracted by the multivariate statistical analysis in descending order were : "satisfactory mastication", "home care", "healthy or poor eyesight", "difficulty in mastication", "being able to independently remove, dentures", "a negative Candida albicans culture test", "no oral dryness", "independents in selecting diet", "comfortable gingival condition", "being dependent on others for tooth-brushing" and "preferable tongue coating", respectively. 4) For the effective preventive countermeasures of oral malodor, ADL of oral health, caring circumstances and hygiene of gingiva/tongue should be focused on rather than dental hygiene itself. en-copyright= kn-copyright= en-aut-name=EgusaMasahiko en-aut-sei=Egusa en-aut-mei=Masahiko kn-aut-name=江草正彦 kn-aut-sei=江草 kn-aut-mei=正彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学講座 en-keyword=Elederly with disabilities kn-keyword=Elederly with disabilities en-keyword=Oral malodor kn-keyword=Oral malodor en-keyword=Preventive countermeasure kn-keyword=Preventive countermeasure en-keyword=Related factor kn-keyword=Related factor en-keyword=Multivariate statistical analysis kn-keyword=Multivariate statistical analysis END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=2 article-no= start-page=141 end-page=146 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Accidents in dental treatment: A questionnaire investigation kn-title=歯科医師の就業状況と診療偶発事故 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The relationship between the operational situation of dental treatment and accidents experienced was investigated through questionnaires sent to members of the Kagawa Dental Association. Responses were received from 261 dentists (53% response rate), of whom 113 (43%) had experienced accidents during dental examinations and/or treatment during the past one year. Dentists with a particularly high risk of having accidents were predominantly young males who possessed many medical chairs at their clinic and who daily examined many patients. Those dentists who worked together with two or more colleagues had a lower risk of accidents. These factors should be considered when trying to take preventive measures against accidents during medical examinations and treatment. en-copyright= kn-copyright= en-aut-name=OnoHiroshi en-aut-sei=Ono en-aut-mei=Hiroshi kn-aut-name=小野廣 kn-aut-sei=小野 kn-aut-mei=廣 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部医学科 en-keyword=歯科診療 (dental treatment) kn-keyword=歯科診療 (dental treatment) en-keyword=偶発事故 (accident) kn-keyword=偶発事故 (accident) en-keyword=質問紙調査 (questionnaires) kn-keyword=質問紙調査 (questionnaires) END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=2 article-no= start-page=113 end-page=117 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Accumulating DNA methylation in background mucosa plays a role in esophageal squamous cell carcinogenesis kn-title=食道扁平上皮癌の発癌過程におけるDNAメチル化の役割 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshiiTatsuhiro en-aut-sei=Ishii en-aut-mei=Tatsuhiro kn-aut-name=石井龍宏 kn-aut-sei=石井 kn-aut-mei=龍宏 aut-affil-num=1 ORCID= en-aut-name=MurakamiJun en-aut-sei=Murakami en-aut-mei=Jun kn-aut-name=村上純 kn-aut-sei=村上 kn-aut-mei=純 aut-affil-num=2 ORCID= en-aut-name=NotoharaKenji en-aut-sei=Notohara en-aut-mei=Kenji kn-aut-name=能登原憲司 kn-aut-sei=能登原 kn-aut-mei=憲司 aut-affil-num=3 ORCID= en-aut-name=SasamotoHiromi en-aut-sei=Sasamoto en-aut-mei=Hiromi kn-aut-name=笹本博美 kn-aut-sei=笹本 kn-aut-mei=博美 aut-affil-num=4 ORCID= en-aut-name=KambaraTakeshi en-aut-sei=Kambara en-aut-mei=Takeshi kn-aut-name=神原健 kn-aut-sei=神原 kn-aut-mei=健 aut-affil-num=5 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=白川靖博 kn-aut-sei=白川 kn-aut-mei=靖博 aut-affil-num=6 ORCID= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=猶本良夫 kn-aut-sei=猶本 kn-aut-mei=良夫 aut-affil-num=7 ORCID= en-aut-name=OuchidaMamoru en-aut-sei=Ouchida en-aut-mei=Mamoru kn-aut-name=大内田守 kn-aut-sei=大内田 kn-aut-mei=守 aut-affil-num=8 ORCID= en-aut-name=ShimizuKenji en-aut-sei=Shimizu en-aut-mei=Kenji kn-aut-name=清水憲二 kn-aut-sei=清水 kn-aut-mei=憲二 aut-affil-num=9 ORCID= en-aut-name=JeremyR. Jass en-aut-sei=Jeremy en-aut-mei=R. Jass kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=MatsubaraNagahide en-aut-sei=Matsubara en-aut-mei=Nagahide kn-aut-name=松原長秀 kn-aut-sei=松原 kn-aut-mei=長秀 aut-affil-num=11 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 歯科口腔放射線学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病態探究医学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 分子遺伝学 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 分子遺伝学 affil-num=10 en-affil= kn-affil=Department of Pathology, McGill University affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 affil-num=12 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 消化器・腫瘍外科学 en-keyword=食道扁平上皮癌 kn-keyword=食道扁平上皮癌 en-keyword=プロモーターメチル化 kn-keyword=プロモーターメチル化 en-keyword=p53遺伝子変異 kn-keyword=p53遺伝子変異 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=小児の歯科恐怖に関する研究-保護者回答用日本語版CFSS-DSの有用性と低年齢児の歯科恐怖の実態- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MoriYukako en-aut-sei=Mori en-aut-mei=Yukako kn-aut-name=森裕佳子 kn-aut-sei=森 kn-aut-mei=裕佳子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ミニスクリューを固定源に用いた矯正歯科治療の臨床的検討‐成功率及び治療効果の比較‐ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamadaKazuyo en-aut-sei=Yamada en-aut-mei=Kazuyo kn-aut-name=山田和代 kn-aut-sei=山田 kn-aut-mei=和代 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=口腔ケア・介護歯科における等温遺伝子増幅法を利用したメチシリン耐性菌の新しい検査法の有用性の検証 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KoideYasushi en-aut-sei=Koide en-aut-mei=Yasushi kn-aut-name=小出康史 kn-aut-sei=小出 kn-aut-mei=康史 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科医師の就業状況と診療偶発事故 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OnoHiroshi en-aut-sei=Ono en-aut-mei=Hiroshi kn-aut-name=小野廣 kn-aut-sei=小野 kn-aut-mei=廣 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=太陽電池を付与した棒状半導体酸化チタンの歯科臨床応用への可能性-Streptococcus mutansに対する光触媒効果- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshiHarumi en-aut-sei=Ishi en-aut-mei=Harumi kn-aut-name=石井敏美 kn-aut-sei=石井 kn-aut-mei=敏美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue= article-no= start-page=105 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Granularity of Asymmetric Screen-Film System kn-title=非対称増感紙フィルム系の粒状性 en-subtitle= kn-subtitle= en-abstract=We have examined a factor affecting the Wiener spectrum measurement of double-emulsion film. An asymmetric screen-film system (Kodak HC/INSIGHT system) was used in this study. The results indicated that the total Wiener spectra of double-emulsion films are higher than the sum of spectra obtained with the front emulsion and back emulsion separately. These differences are attributed to the arrangement of the optical system of the microdensitometer used to measure and the structure of double-emulsion film. kn-abstract=非対称増感紙フィルム系について、両面乳剤フィルムのウィナースペクトル測定に及ぼす影響を検討した。濃度0.5~2.5のノイズ試料のフロント乳剤、バック乳剤、支持体層それぞれで測定したスペクトルの和と、両面同時に測定した全スペクトルとを比較した。その結果、全ウィナースペクトルの値は、フロント乳剤、バック乳剤の和より高くなった。また、試料濃度が高いほど、その差は大きくなった。これらは、マイクロデンシトメータの光学系の配置と両面乳剤フィルムの構造に起因している。したがって、非対称システムのようにフィルムの前面と後面で特性を分けて考える場合、注意を要する。 en-copyright= kn-copyright= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=本田貢 kn-aut-sei=本田 kn-aut-mei=貢 aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=吉田彰 kn-aut-sei=吉田 kn-aut-mei=彰 aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=中村伸枝 kn-aut-sei=中村 kn-aut-mei=伸枝 aut-affil-num=3 ORCID= en-aut-name=MimuraSeiichi en-aut-sei=Mimura en-aut-mei=Seiichi kn-aut-name=三村誠一 kn-aut-sei=三村 kn-aut-mei=誠一 aut-affil-num=4 ORCID= en-aut-name=KadohisaSigefumi en-aut-sei=Kadohisa en-aut-mei=Sigefumi kn-aut-name=門久繁文 kn-aut-sei=門久 kn-aut-mei=繁文 aut-affil-num=5 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=6 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=7 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=竹内知行 kn-aut-sei=竹内 kn-aut-mei=知行 aut-affil-num=8 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=7 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=8 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=9 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=非対称増感紙フィルム系 (asymmetric screen-film system) kn-keyword=非対称増感紙フィルム系 (asymmetric screen-film system) en-keyword=両面乳剤フィルム (double-emulsion film) kn-keyword=両面乳剤フィルム (double-emulsion film) en-keyword=ウィナースペクトル (Wiener spectrum) kn-keyword=ウィナースペクトル (Wiener spectrum) en-keyword=粒状性 (granularity) kn-keyword=粒状性 (granularity) en-keyword=マイクロデンシトメータ (microdensitometer) kn-keyword=マイクロデンシトメータ (microdensitometer) END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=75 end-page=82 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analysis of Tempormandibular Joint by Image Processing -Discrimination of Condylar Position- kn-title=画像処理による顎関節の解析 ―下顎頭位の判別― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Tomography is clinically useful in the diagnosis of the temporomandibular joint (TMJ) syndrome. The TMJ is formed by the condyle and the glenoid fossa, and there exists TMJ space between them. Image processing was employed in the present study, and the reference points of the condyle and the glenoid fossa were determined from the tomogram. Subsequently, the TMJ space was measured automatically in the image analysis. The TMJs of 98 patients were examined practically and the characteristics of each result were studied. There is a possibility of discriminating an abnormal condylar position from a normal one by making use of the TMJ space and the distance between two reference points. en-copyright= kn-copyright= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=1 ORCID= en-aut-name=GotouSachiko en-aut-sei=Gotou en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=2 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=3 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=中村伸枝 kn-aut-sei=中村 kn-aut-mei=伸枝 aut-affil-num=4 ORCID= en-aut-name=ShibuyaKouichi en-aut-sei=Shibuya en-aut-mei=Kouichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=5 ORCID= en-aut-name=YamadaToshiharu en-aut-sei=Yamada en-aut-mei=Toshiharu kn-aut-name=山田俊治 kn-aut-sei=山田 kn-aut-mei=俊治 aut-affil-num=6 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=7 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=Condylar Position kn-keyword=Condylar Position en-keyword=Temporomandibular Joint Space kn-keyword=Temporomandibular Joint Space en-keyword=Image Processing kn-keyword=Image Processing en-keyword=Tomogram kn-keyword=Tomogram en-keyword=Discrimination kn-keyword=Discrimination END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=99 end-page=104 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Physical Image Quality of Rapid Processing Films kn-title=迅速処理用X線フィルムの物理特性 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The imaging properties of Konica "new" SR series films and "old" MG-SR series films for rapid processing were measured in combination with green-emitting intensifying screens. The measured image quality prarameters include: characteristic curve, modulation transfer function (MTF) and Wiener spectrum. The relative speeds of the new SR series systems were slower than those of the old MG-SR series systems from 10 to 25%. The MTF's of the new systems were generally comparable to those of the old systems, except that SR-G system was improved with an increase of approximately 10%. In the Wiener spectrum measurement, however, the new systems showed from 10 to 35% decrease in low-frequency noise. en-copyright= kn-copyright= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=吉田彰 kn-aut-sei=吉田 kn-aut-mei=彰 aut-affil-num=1 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=本田貢 kn-aut-sei=本田 kn-aut-mei=貢 aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=中村伸枝 kn-aut-sei=中村 kn-aut-mei=伸枝 aut-affil-num=3 ORCID= en-aut-name=AriokaTadashi en-aut-sei=Arioka en-aut-mei=Tadashi kn-aut-name=有岡匡 kn-aut-sei=有岡 kn-aut-mei=匡 aut-affil-num=4 ORCID= en-aut-name=KobashiToshimi en-aut-sei=Kobashi en-aut-mei=Toshimi kn-aut-name=小橋利美 kn-aut-sei=小橋 kn-aut-mei=利美 aut-affil-num=5 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=竹内知行 kn-aut-sei=竹内 kn-aut-mei=知行 aut-affil-num=6 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=三上泰隆 kn-aut-sei=三上 kn-aut-mei=泰隆 aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=3 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=8 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=Rapid Processing Films kn-keyword=Rapid Processing Films en-keyword=Image Quality kn-keyword=Image Quality en-keyword=Characteristic Curve kn-keyword=Characteristic Curve en-keyword=MTF kn-keyword=MTF en-keyword=Wiener Spectrum kn-keyword=Wiener Spectrum END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=81 end-page=88 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920205 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=RESOLUTION PROPERTIES OF CRT MONITORS kn-title=CRTモニタの解像特性 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have developed a new technique for measuring the modulation transfer function (MTF) of a cathode ray tube (CRT) monitor. The "nominal" MTF was measured by displaying a line image of a width of one pixel on the CRT monitor using the pattern generator. We also measured the effective pixel width. In order to obtain the "actual" MTF, the nominal MTF was divided by the sinc function which is the Fourier transform of the effective pixel width. The results indicate that the corrected MTF converges to the constant value as the effective pixel width is narrower. Thus, the actual MTFs were determined and compared in the horizontal direction for two CRT monitors. en-copyright= kn-copyright= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=竹内知行 kn-aut-sei=竹内 kn-aut-mei=知行 aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=吉田彰 kn-aut-sei=吉田 kn-aut-mei=彰 aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=3 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=4 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=中村伸枝 kn-aut-sei=中村 kn-aut-mei=伸枝 aut-affil-num=5 ORCID= en-aut-name=KishiKanji en-aut-sei=Kishi en-aut-mei=Kanji kn-aut-name=岸幹二 kn-aut-sei=岸 kn-aut-mei=幹二 aut-affil-num=6 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=6 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=CRT Monitor kn-keyword=CRT Monitor en-keyword=Resolution kn-keyword=Resolution en-keyword=Effective Pixel Width kn-keyword=Effective Pixel Width en-keyword=Modulation Transfer Function (MTF) kn-keyword=Modulation Transfer Function (MTF) END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=7 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Physical Properties of Screen-Film Systems - New System for Chest Radiography - kn-title=増感紙フィルム系の物理特性 ―胸部用新システム― en-subtitle= kn-subtitle= en-abstract=The new three screen-film systems, Kodack INSIGHT system HC/IT-1, Fuji AD system HG-M/UR-1, and Konica EX system XG-S/ES-C for chest radiography were evaluated. In addition, the conventional system Fuji HR-4/Super HR-S was measured for comparison with new systems. The evaluation method is as follows. The image quality characteristics, speed, contrast, resolution and granularity were measured. The sensitivity and contrast were determined by measuring the MTF (modulation transfer function) and NCTF (normalized contrast transfer function). The granularity was estimated by measuring the Wiener spectrum. The speed of the new systems were improved by 22% to 73%. The dinsities at the maximum gradient value were shifted to high density (2.0-2.7). However, they had 10% to 30% less resolution. The other hand, the granularities were improved by 21% to 37% at 1.0 density. These results suggested that the emphasis of new systems was put on improving the image quality of mediastinum region, maintaining performance of the conventional system. kn-abstract=胸部専用の新しい増感紙/フィルムシステムについて物理的画質特性を測定し、従来のシステムと比較を行った。測定した新システムは、日本コダックのインサイトシステムからHC/IT-1、富士メディカルシステムのADシステムからHG-M/UR-1、コニカのEXシステムからXG-S/ES-C である。従来のシステムとして富士メディカルシステムのHR-4/Super HR-S を使用した。その結果、新システムは22~73%感度は高く、特性曲線においては低濃度部を持ち上げ、最大コントラストは高濃度側にシフトしていた。空間周波数2cycles/mmで相対鮮鋭度を比較すると、新システムが10~30%程度の低下となっていた。ノイズは、濃度1.0で新システムが35~46%の減少となった。以上より、新システムは、縦隔部の濃度を上げ、粒状性の改善を重視した設計となっていることが分かった。 en-copyright= kn-copyright= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=吉田彰 kn-aut-sei=吉田 kn-aut-mei=彰 aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=中村伸枝 kn-aut-sei=中村 kn-aut-mei=伸枝 aut-affil-num=3 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=4 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=5 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=6 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=8 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=本田貢 kn-aut-sei=本田 kn-aut-mei=貢 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=広島県立保健福祉短期大学部放射線技術科学科 affil-num=3 en-affil= kn-affil=岡山大学歯学部附属病院歯科放射線科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=8 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=増感紙フィルム系 (screen-film system) kn-keyword=増感紙フィルム系 (screen-film system) en-keyword=物理特性 (physical properties) kn-keyword=物理特性 (physical properties) en-keyword=感度 (speed (film sensitivity)) kn-keyword=感度 (speed (film sensitivity)) en-keyword=コントラスト (contrast) kn-keyword=コントラスト (contrast) en-keyword=鮮鋭度 (resolution) kn-keyword=鮮鋭度 (resolution) en-keyword=粒状性 (granularity) kn-keyword=粒状性 (granularity) END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=1 article-no= start-page=25 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001116 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=歯科インプラント動揺測定装置の開発 kn-title=Development of a dental implant movement checker en-subtitle= kn-subtitle= en-abstract=臨床歯科において,歯の動揺度診査が日常的に行われているのと同じように,近年行われるようになってきた歯科インプラント施術においても,その植立評価は重要である。歯の動揺は,歯の治療計画において,また予後の評価においても重要な情報を与えてくれる。本研究では,その植立評価を行うために,インプラントの動揺に着目した。動揺を簡便にかつ定量的に測定するために,著者らがすでに開発したT-Mテスタ(Tooth Mobility tester)を改良して,IMチェッカ(Implant Mobility Checker)を開発した。IMチェッカは測定プローブと増幅器などのインタフェース,演算処理用のノートパソコンから構成される。測定プローブは圧電素子を2枚重ねたバイモルフ構造で,単一周波数の振動駆動と加速度検出を行い,口腔内でも測定ができるほどに小型に設計した。ノートパソコンでは得られた加速度信号をデータ処理し,IM値を算出する。IM値は,測定周波数と駆動力が一 定の場合,インプラント周囲の機械モビリティに比例するので,インプラントの動揺を数値化することができる。内可動性機構をもつIMZタイプのインプラントを埋植したモデルを製作し,そのIM値を測定した。インプラント周囲の材料(モルテノ(@))の硬さを変えた2種類のモデルを作製したところ,歯科医による臨床的動揺度診査はいずれもM0であったが,本チェッカによってその動揺の差を測定したところ,IM値は29と58となり,客観的に動揺の差を評価することができた。試作したIMチェッカで測定したところ,一歯の測定時間は約15秒以下であり,また測定のばらつきは術者内で平均6%以下,また術者間で6%以下であった。一方,従来のアナログ型T-Mテスタと比較したところ,天然歯の測定において,測定のばらつきは51%,測定時間は61%減少させることができた。従って,IMチェッカは十分な測定精度を確保できており,今後,臨床での試用を行いたいと考える。 kn-abstract=Evaluation of dental implantation is very important because it gives useful information for both planning the dental treatment and evaluating of prognosis. This study aimed at improving our previously developed Tooth Mobility (TM) tester and developing a dental implant movement (IM) checker. The measuring probe included a bimorph transducer of two piezoelectric elements. It was actuated by single frequency and detected tooth acceleration. The acceleration signal was processed and the IM score was calculated in PC. Two artificial implant models in which IMZ implant was buried with different elasticity of surrounding (molteno(@)) were used to examine the performance of the IM checker. The IM scores obtained in the models were 29 and 58. The measurement time was below 15 seconds. The average of measurement variation of one operator was below 6% and the average variation among five operators was below also 6%. The IM checker reduced a measurement variation by 51% and a measuring time by 61% compared with those of the TM tester in natural teeth. The newly developed IM checker had sufficient measuring reliability and we could objectively estimate the implant movement in dental clinics. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=1 ORCID= en-aut-name=OnoKoichi en-aut-sei=Ono en-aut-mei=Koichi kn-aut-name=小野浩一 kn-aut-sei=小野 kn-aut-mei=浩一 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=WijayaSastra Kusuma kn-aut-sei=Wijaya kn-aut-mei=Sastra Kusuma aut-affil-num=3 ORCID= en-aut-name=SarataniKeiji en-aut-sei=Saratani en-aut-mei=Keiji kn-aut-name=更谷啓治 kn-aut-sei=更谷 kn-aut-mei=啓治 aut-affil-num=4 ORCID= en-aut-name=KawazoeTakayoshi en-aut-sei=Kawazoe en-aut-mei=Takayoshi kn-aut-name=川添堯彬 kn-aut-sei=川添 kn-aut-mei=堯彬 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科検査技術科学専攻 affil-num=2 en-affil= kn-affil=㈱エプソン・プリンタ設計グループ affil-num=3 en-affil= kn-affil=岡山大学大学院自然科学研究科知能開発科学専攻 affil-num=4 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 affil-num=5 en-affil= kn-affil=大阪歯科大学有歯補綴咬合学講座 en-keyword=tooth mobility (歯の動揺) kn-keyword=tooth mobility (歯の動揺) en-keyword=mechanical mobility (機械モビリティ) kn-keyword=mechanical mobility (機械モビリティ) en-keyword=dental implant (インプラント) kn-keyword=dental implant (インプラント) en-keyword=manual examination (触診) kn-keyword=manual examination (触診) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=一歯科医院におけるコーヌステレスコープ義歯と部分床義歯の予後調査の比較 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShimamuraKoichi en-aut-sei=Shimamura en-aut-mei=Koichi kn-aut-name=嶋村浩一 kn-aut-sei=嶋村 kn-aut-mei=浩一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=一歯科医院における根管治療の予後調査 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TsujiKozo en-aut-sei=Tsuji en-aut-mei=Kozo kn-aut-name=辻耕造 kn-aut-sei=辻 kn-aut-mei=耕造 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科インプラントの生体組織との融合性に関する基礎的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=趙佳明 kn-aut-sei=趙 kn-aut-mei=佳明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=小児の歯科恐怖に関する疫学的研究-日本語版CFSS-DSの有用性と歯科恐怖の実態- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HirakawaTakayuki en-aut-sei=Hirakawa en-aut-mei=Takayuki kn-aut-name=平川貴之 kn-aut-sei=平川 kn-aut-mei=貴之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科臨床における臨床検査の重要性の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsumuraJun en-aut-sei=Matsumura en-aut-mei=Jun kn-aut-name=松村淳 kn-aut-sei=松村 kn-aut-mei=淳 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=歯科インプラントの安定性および形状アセスメントのための機械モビリティ技法に関する研究 kn-title=Mechanical Mobility Technique for Stability and Geometry Assessment of Dental Implant en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WijayaSastra Kusuma en-aut-sei=Wijaya en-aut-mei=Sastra Kusuma kn-aut-name=ウィジャヤサストラ クスマ kn-aut-sei=ウィジャヤ kn-aut-mei=サストラ クスマ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科恐怖の予防に関する行動科学的研究 質問紙法による評定尺度の考案 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=壺内智郎 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en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田口マルセーラ文代 kn-aut-sei=田口 kn-aut-mei=マルセーラ文代 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=小児歯科臨床における歯科恐怖に関する行動科学鼻部皮膚表面温度と行動との関連性 kn-title=Behavioral science on dental fear in pediatric dentistry : Relationship between behavior and the nasal skin temperature en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=仲井雪絵 kn-aut-sei=仲井 kn-aut-mei=雪絵 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科における行動科学 -不安、行動および鼻部皮膚表面温度との関係- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中村隆子 kn-aut-sei=中村 kn-aut-mei=隆子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=小児歯科における行動科学 バイオモニタリングシステムの開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大町耕市 kn-aut-sei=大町 kn-aut-mei=耕市 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=小児歯科における行動科学 精神発達と鼻部皮膚表面温度変化様式との関連性 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=山根秀文 kn-aut-sei=山根 kn-aut-mei=秀文 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=歯科用ポーセレンと接着性レジンの接着における被着面処理に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=今井誠 kn-aut-sei=今井 kn-aut-mei=誠 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19901031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=複合電析による歯科用金属の被着面処理法に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=近藤康弘 kn-aut-sei=近藤 kn-aut-mei=康弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=歯科不安の評価に関する研究 特性不安と状態不安および鼻部皮膚表面温度との関連性 kn-title=The assessment of dental anxiety:its relationships with trait anxiety, state anxiety,and nasal skin temperature en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=吉田登志子 kn-aut-sei=吉田 kn-aut-mei=登志子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 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