start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue= article-no= start-page=49 end-page=73 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Mechanism in Leibniz from a Medical-Philosophical Point of View kn-title=ライプニッツの機械論―医学哲学的観点から en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MATSUDATsuyoshi en-aut-sei=MATSUDA en-aut-mei=Tsuyoshi kn-aut-name=松田毅 kn-aut-sei=松田 kn-aut-mei=毅 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院社会文化科学研究科 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=141 end-page=141 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 108th Annual Meeting of the Japanese Society of Legal Medicine kn-title=第108次日本法医学会学術全国集会開催報告 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MiyaishiSatoru en-aut-sei=Miyaishi en-aut-mei=Satoru kn-aut-name=宮石智 kn-aut-sei=宮石 kn-aut-mei=智 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Legal Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　法医学 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=139 end-page=140 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Generative AI kn-title=生成 AI en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KodaMasahide en-aut-sei=Koda en-aut-mei=Masahide kn-aut-name=香田将英 kn-aut-sei=香田 kn-aut-mei=将英 aut-affil-num=1 ORCID= affil-num=1 en-affil=Co-learning Community Healthcare Re-innovation Office, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　地域医療共育推進オフィス END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=135 end-page=138 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Drug interaction (61. Drug interactions of cancer cachexia therapeutics) kn-title=薬物相互作用（61―がん悪液質治療薬の相互作用） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KawakamiEiji en-aut-sei=Kawakami en-aut-mei=Eiji kn-aut-name=川上英治 kn-aut-sei=川上 kn-aut-mei=英治 aut-affil-num=1 ORCID= en-aut-name=OkudaHiroto en-aut-sei=Okuda en-aut-mei=Hiroto kn-aut-name=奥田浩人 kn-aut-sei=奥田 kn-aut-mei=浩人 aut-affil-num=2 ORCID= en-aut-name=HamanoHirofumi en-aut-sei=Hamano en-aut-mei=Hirofumi kn-aut-name=濱野裕章 kn-aut-sei=濱野 kn-aut-mei=裕章 aut-affil-num=3 ORCID= en-aut-name=ZamamiYoshito en-aut-sei=Zamami en-aut-mei=Yoshito kn-aut-name=座間味義人 kn-aut-sei=座間味 kn-aut-mei=義人 aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=2 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=3 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=4 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=132 end-page=134 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ulcerative colitis kn-title=潰瘍性大腸炎 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HiraokaSakiko en-aut-sei=Hiraoka en-aut-mei=Sakiko kn-aut-name=平岡佐規子 kn-aut-sei=平岡 kn-aut-mei=佐規子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Inflammatory Bowel Disease Center, Okayama University Hospital kn-affil=岡山大学病院　炎症性腸疾患センター en-keyword=潰瘍性大腸炎 kn-keyword=潰瘍性大腸炎 en-keyword=炎症性腸疾患 kn-keyword=炎症性腸疾患 en-keyword=診断 kn-keyword=診断 en-keyword=治療 kn-keyword=治療 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=127 end-page=131 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Eosinophilic chronic rhinosinusitis kn-title=好酸球性副鼻腔炎 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MakiharaSeiichiro en-aut-sei=Makihara en-aut-mei=Seiichiro kn-aut-name=牧原靖一郎 kn-aut-sei=牧原 kn-aut-mei=靖一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Otolaryngology-Head & Neck Surgery, Okayama University Hospital kn-affil=岡山大学病院　耳鼻咽喉・頭頸部外科 en-keyword=好酸球性副鼻腔炎 kn-keyword=好酸球性副鼻腔炎 en-keyword=診断基準 kn-keyword=診断基準 en-keyword=治療 kn-keyword=治療 en-keyword=気管支喘息 kn-keyword=気管支喘息 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=120 end-page=126 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of parity on the associations between evacuation and psychological distress and cardiovascular disease among women after the Great East Japan Earthquake : A cross-sectional study of the Fukushima Health Management Survey kn-title=東日本大震災後の女性における出産歴が避難と精神的苦痛や循環器疾患との関連に及ぼす影響：福島県「県民健康調査」を用いた横断研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Introduction : Women are more likely to be physically, mentally, and socially vulnerable after disasters because of the physical, socioeconomical, and lifestyle-related factors that are often related to their parity. Here, we analyzed the effects of women's parity on the association between evacuation and psychological distress, trauma reactions, and cardiovascular disease (CVD).
　Participants and Methods : The participants were residents living in 13 municipalities in the evacuation zone of Japan's Fukushima Prefecture after the March 11, 2011 Great East Japan Earthquake who responded to the Fukushima Health Management Survey in FY2012. A total of 30,709 women aged 40-90 years were included in the analyses. We performed a logistic regression analysis to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for CVD risk factors.
　Results : A multivariate analysis revealed that among the parous women (n = 19,608), evacuation was associated with psychological distress (adjusted OR 1.30, 95%CI : 1.17-1.44), trauma reactions (OR 1.22, 95%CI : 1.11-1.35), and heart disease (OR 1.14, 95%CI : 1.03-1.26) compared to the non-evacuation status. Among the nulliparous women (n = 1,794), there was no association between the evacuation and any outcomes.
　Conclusion : The evacuation of individuals after the Great East Japan Earthquake was associated with psychological distress, trauma reactions, and heart disease, especially among parous women. en-copyright= kn-copyright= en-aut-name=YasukawaSumiyo en-aut-sei=Yasukawa en-aut-mei=Sumiyo kn-aut-name=安川純代 kn-aut-sei=安川 kn-aut-mei=純代 aut-affil-num=1 ORCID= en-aut-name=EguchiEri en-aut-sei=Eguchi en-aut-mei=Eri kn-aut-name=江口依里 kn-aut-sei=江口 kn-aut-mei=依里 aut-affil-num=2 ORCID= en-aut-name=OhiraTetsuya en-aut-sei=Ohira en-aut-mei=Tetsuya kn-aut-name=大平哲也 kn-aut-sei=大平 kn-aut-mei=哲也 aut-affil-num=3 ORCID= en-aut-name=HayashiFumikazu en-aut-sei=Hayashi en-aut-mei=Fumikazu kn-aut-name=林史和 kn-aut-sei=林 kn-aut-mei=史和 aut-affil-num=4 ORCID= en-aut-name=SakaiAkira en-aut-sei=Sakai en-aut-mei=Akira kn-aut-name=坂井晃 kn-aut-sei=坂井 kn-aut-mei=晃 aut-affil-num=5 ORCID= en-aut-name=ShimabukuroMichio en-aut-sei=Shimabukuro en-aut-mei=Michio kn-aut-name=島袋充生 kn-aut-sei=島袋 kn-aut-mei=充生 aut-affil-num=6 ORCID= en-aut-name=FujimoriKeiya en-aut-sei=Fujimori en-aut-mei=Keiya kn-aut-name=藤森敬也 kn-aut-sei=藤森 kn-aut-mei=敬也 aut-affil-num=7 ORCID= en-aut-name=MiuraItaru en-aut-sei=Miura en-aut-mei=Itaru kn-aut-name=三浦至 kn-aut-sei=三浦 kn-aut-mei=至 aut-affil-num=8 ORCID= en-aut-name=YabeHirooki en-aut-sei=Yabe en-aut-mei=Hirooki kn-aut-name=矢部博興 kn-aut-sei=矢部 kn-aut-mei=博興 aut-affil-num=9 ORCID= en-aut-name=MaedaMasaharu en-aut-sei=Maeda en-aut-mei=Masaharu kn-aut-name=前田正治 kn-aut-sei=前田 kn-aut-mei=正治 aut-affil-num=10 ORCID= en-aut-name=YasumuraSeiji en-aut-sei=Yasumura en-aut-mei=Seiji kn-aut-name=安村誠司 kn-aut-sei=安村 kn-aut-mei=誠司 aut-affil-num=11 ORCID= affil-num=1 en-affil=Department of Nursing, Faculty of Health Sciences, Okayama University kn-affil=岡山大学学術研究院保健学域　看護学 affil-num=2 en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University kn-affil=福島県立医科大学医学部　疫学 affil-num=3 en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University kn-affil=福島県立医科大学医学部　疫学 affil-num=4 en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University kn-affil=福島県立医科大学医学部　疫学 affil-num=5 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=6 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=7 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=8 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=9 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=10 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター affil-num=11 en-affil=Radiation Medical Science Center, Fukushima Medical University kn-affil=福島県立医科大学放射線医学県民健康管理センター en-keyword=東日本大震災（the Great East Japan Earthquake） kn-keyword=東日本大震災（the Great East Japan Earthquake） en-keyword=大規模災害（large disaster） kn-keyword=大規模災害（large disaster） en-keyword=出産歴（parity） kn-keyword=出産歴（parity） en-keyword=精神的苦痛（psychological distress） kn-keyword=精神的苦痛（psychological distress） en-keyword=循環器疾患（cardiovascular disease） kn-keyword=循環器疾患（cardiovascular disease） END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=112 end-page=119 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Evaluation of empathy in nursing students : Empathy in everyday situations and empathy as healthcare professionals kn-title=看護学生における共感性の検討―日常場面での共感性と医療者としての共感性から― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Empathy is crucial for building an effective patient-nurse relationship. This study aimed to examine two aspects of nursing students' empathy : their empathy in everyday situations and their empathy as healthcare professionals.
　This study involved 214 female students in their second to fourth years of nursing studies at a university, with analysis focusing on 118 participants. The Empathy Experience Scale Revised (EESR) was used to measure empathy in everyday situations, and the Jefferson Empathy Scale, Health Professionals version (JSE, HP-Version) measured the participants' empathy as healthcare professionals. The EESR comprises the Scale of Shared Experiences (SSE) and the Scale of Insufficient Sharing Experience (SISE) ; the JSE comprises Perspective Taking, Compassionate Care, and Standing in the Patient's Shoes.
　The total JSE scores and the Perspective Taking subfactor scores tended to be higher in fourth-year students, who also showed SISE scores significantly lower than those of students with fewer years of nursing study. Relationship analysis showed a moderate positive correlation between SSE scores and Perspective Taking scores. There was a weak negative correlation between SISE and Standing in the Patient's Shoes scores. Compassionate Care scores were not significantly related to SSE or SISE scores. These results suggest that nursing students' empathy as healthcare professionals increases as they advance in their nursing studies, and emphasize the importance of scale selection in measuring empathy. en-copyright= kn-copyright= en-aut-name=NagoshiShiori en-aut-sei=Nagoshi en-aut-mei=Shiori kn-aut-name=名越史織 kn-aut-sei=名越 kn-aut-mei=史織 aut-affil-num=1 ORCID= en-aut-name=MatsumotoRiho en-aut-sei=Matsumoto en-aut-mei=Riho kn-aut-name=松本梨穂 kn-aut-sei=松本 kn-aut-mei=梨穂 aut-affil-num=2 ORCID= en-aut-name=KajiwaraYuki en-aut-sei=Kajiwara en-aut-mei=Yuki kn-aut-name=梶原右揮 kn-aut-sei=梶原 kn-aut-mei=右揮 aut-affil-num=3 ORCID= en-aut-name=MorimotoMichiko en-aut-sei=Morimoto en-aut-mei=Michiko kn-aut-name=森本美智子 kn-aut-sei=森本 kn-aut-mei=美智子 aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Nursing, Faculty of Health Sciences, Okayama University Medical School kn-affil=岡山大学医学部保健学科　看護学 affil-num=2 en-affil=Department of Nursing, Faculty of Health Sciences, Okayama University Medical School kn-affil=岡山大学医学部保健学科　看護学 affil-num=3 en-affil=Division of Nursing, Faculty of Health Sciences, Okayama University kn-affil=岡山大学学術研究院保健学域　看護学 affil-num=4 en-affil=Division of Nursing, Faculty of Health Sciences, Okayama University kn-affil=岡山大学学術研究院保健学域　看護学 en-keyword=看護学生（nursing students） kn-keyword=看護学生（nursing students） en-keyword=共感性（empathy） kn-keyword=共感性（empathy） en-keyword=尺度（scale） kn-keyword=尺度（scale） END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=107 end-page=111 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Changes in the drug discovery environment and the roles required of academic researchers kn-title=創薬環境の変遷とアカデミア研究者に求められる役割について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NakayamaMasanori en-aut-sei=Nakayama en-aut-mei=Masanori kn-aut-name=中山雅敬 kn-aut-sei=中山 kn-aut-mei=雅敬 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Pathophysiology and Drug Discovery, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　病態生理・創薬学 en-keyword=創薬 kn-keyword=創薬 en-keyword=創薬エコシステム kn-keyword=創薬エコシステム en-keyword=スタートアップ kn-keyword=スタートアップ END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=100 end-page=106 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Balneotherapy for chronic respiratory diseases in the older people kn-title=高齢者慢性呼吸器疾患に対する温泉療法 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MitsunobuFumihiro en-aut-sei=Mitsunobu en-aut-mei=Fumihiro kn-aut-name=光延文裕 kn-aut-sei=光延 kn-aut-mei=文裕 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Longevity and Social Medicine (Geriatrics), Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　老年医学 en-keyword=高齢者 kn-keyword=高齢者 en-keyword=慢性閉塞性肺疾患（COPD） kn-keyword=慢性閉塞性肺疾患（COPD） en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=温泉療法 kn-keyword=温泉療法 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=97 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize) kn-title=令和５年度岡山医学会賞　胸部・循環研究奨励賞（砂田賞） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TaniguchiAkihiko en-aut-sei=Taniguchi en-aut-mei=Akihiko kn-aut-name=谷口暁彦 kn-aut-sei=谷口 kn-aut-mei=暁彦 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Hematology, Oncology, Allergy and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　血液・腫瘍・呼吸器内科学 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=94 end-page=96 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize) kn-title=令和５年度岡山医学会賞　がん研究奨励賞（林原賞・山田賞） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ObataTaisuke en-aut-sei=Obata en-aut-mei=Taisuke kn-aut-name=小幡泰介 kn-aut-sei=小幡 kn-aut-mei=泰介 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=3 article-no= start-page=91 end-page=93 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize) kn-title=令和５年度岡山医学会賞　総合研究奨励賞（結城賞） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeHaruki en-aut-sei=Watanabe en-aut-mei=Haruki kn-aut-name=渡辺晴樹 kn-aut-sei=渡辺 kn-aut-mei=晴樹 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　腎・免疫・内分泌代謝学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラットモデルにおけるくも膜下出血発症後急性期における脳波抑制は早期脳損傷の重要なマーカーである kn-title=Power suppression in EEG after the onset of SAH is a 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Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=癌関連線維芽細胞を標的とした光免疫療法は腫瘍免疫の再構築に寄与する kn-title=Fibroblast activation protein-targeted near-infrared photoimmunotherapy depletes immunosuppressive cancer-associated fibroblasts and remodels local tumor immunity en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AKAIMasaaki en-aut-sei=AKAI en-aut-mei=Masaaki kn-aut-name=赤井正明 kn-aut-sei=赤井 kn-aut-mei=正明 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=T細胞腫瘍におけるα-ピネンの抗腫瘍活性 kn-title=Antitumor activity of α-pinene in T-cell tumors en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ABEMasaya en-aut-sei=ABE en-aut-mei=Masaya kn-aut-name=阿部将也 kn-aut-sei=阿部 kn-aut-mei=将也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=トランス男性は低用量テストステロン療法で十分な筋肉発達を達成できる： 体組成の変化に関する長期研究 kn-title=Trans men can achieve adequate muscular development through low-dose testosterone therapy: A long-term study on body composition changes en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TOMINAGAYusuke en-aut-sei=TOMINAGA en-aut-mei=Yusuke kn-aut-name=富永悠介 kn-aut-sei=富永 kn-aut-mei=悠介 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=小児肝移植におけるレシピエントの年齢が周術期合併症に及ぼす影響：単施設後ろ向き研究 kn-title=Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-center Retrospective Study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KATAYAMAAkira en-aut-sei=KATAYAMA en-aut-mei=Akira kn-aut-name=片山明 kn-aut-sei=片山 kn-aut-mei=明 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=p53搭載テロメラーゼ特異的腫瘍溶解アデノウイルスによる膵臓癌における長期抗腫瘍免疫の活性化 kn-title=Long-term activation of anti-tumor immunity in pancreatic cancer by a p53-expressing telomerase-specific oncolytic adenovirus en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HASHIMOTOMasashi en-aut-sei=HASHIMOTO en-aut-mei=Masashi kn-aut-name=橋本将志 kn-aut-sei=橋本 kn-aut-mei=将志 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=患者腫瘍移植モデルに対するヒト化抗Fibroblast Atcivation Protein抗体を用い癌関連線維芽細胞を標的とした光免疫療法 kn-title=Near-infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Patient-Derived Xenografts Using a Humanized Anti-Fibroblast Activation Protein Antibody en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KOBAYASHITeruki en-aut-sei=KOBAYASHI en-aut-mei=Teruki kn-aut-name=小林照貴 kn-aut-sei=小林 kn-aut-mei=照貴 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=悪性末梢神経鞘腫瘍においてPRRX1とTOP2Aのタンパク質間相互作用は悪性化を促進させる kn-title=PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TAKIHIRAShota en-aut-sei=TAKIHIRA en-aut-mei=Shota kn-aut-name=逡ｽ将太 kn-aut-sei=逡ｽ kn-aut-mei=将太 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=老化線維芽細胞はIL-8のクロストークを介し、びまん性胃癌細胞の腹膜転移を促進する kn-title=Senescent Fibroblasts Potentiate Peritoneal Metastasis of Diffuse-type Gastric Cancer Cells via IL-8?mediated Crosstalk en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=LIYUNCHENG en-aut-sei=LI en-aut-mei=YUNCHENG kn-aut-name=李云成 kn-aut-sei=李 kn-aut-mei=云成 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=4D-CT Angiographyによる腎細胞癌の栄養動脈の描出率 kn-title=Depiction rate of feeding arteries of renal cell carcinoma on four?dimensional computed tomography angiography en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MUNETOMOKazuaki en-aut-sei=MUNETOMO en-aut-mei=Kazuaki kn-aut-name=宗友一晃 kn-aut-sei=宗友 kn-aut-mei=一晃 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ADAR1は大腸癌肝転移切除後の残肝再発の有望なリスク層別化バイオマーカーである kn-title=ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HATANanako en-aut-sei=HATA en-aut-mei=Nanako kn-aut-name=畑七々子 kn-aut-sei=畑 kn-aut-mei=七々子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=軟骨無形成症の新生児および乳幼児における骨格成長の放射線学的特徴 kn-title=Radiological characteristics of skeletal growth in neonates and infants with achondroplasia en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MIYAHARADaisuke en-aut-sei=MIYAHARA en-aut-mei=Daisuke kn-aut-name=宮原大輔 kn-aut-sei=宮原 kn-aut-mei=大輔 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=血中循環遊離DNAのメチル化パターンは、原発巣遺伝子変異プロファイルによらず、大腸癌の治療効果モニタリングを可能とする非侵襲的なバイオマーカーである kn-title=Circulating cell?free DNA methylation patterns as non?invasive biomarkers to monitor colorectal cancer treatment efficacy without referencing primary site mutation profiles en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YASUIKazuya en-aut-sei=YASUI en-aut-mei=Kazuya kn-aut-name=安井和也 kn-aut-sei=安井 kn-aut-mei=和也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=85 end-page=90 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 123nd General Assembly of the Okayama Medical Association kn-title=第123回　岡山医学会総会 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=83 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=mRNA-vaccine kn-title=mRNA ワクチン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TanakaYuta en-aut-sei=Tanaka en-aut-mei=Yuta kn-aut-name=田中雄太 kn-aut-sei=田中 kn-aut-mei=雄太 aut-affil-num=1 ORCID= en-aut-name=ZamamiYoshito en-aut-sei=Zamami en-aut-mei=Yoshito kn-aut-name=座間味義人 kn-aut-sei=座間味 kn-aut-mei=義人 aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=2 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=80 end-page=82 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Drug interaction (60. Chronic pain treatment drugs) kn-title=薬物相互作用（60―慢性疼痛治療薬の薬物相互作用） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakahashiTetta en-aut-sei=Takahashi en-aut-mei=Tetta kn-aut-name=橋徹多 kn-aut-sei=橋 kn-aut-mei=徹多 aut-affil-num=1 ORCID= en-aut-name=HigashionnaTsukasa en-aut-sei=Higashionna en-aut-mei=Tsukasa kn-aut-name=東恩納司 kn-aut-sei=東恩納 kn-aut-mei=司 aut-affil-num=2 ORCID= en-aut-name=HamanoHirohumi en-aut-sei=Hamano en-aut-mei=Hirohumi kn-aut-name=濱野裕章 kn-aut-sei=濱野 kn-aut-mei=裕章 aut-affil-num=3 ORCID= en-aut-name=ZamamiYoshito en-aut-sei=Zamami en-aut-mei=Yoshito kn-aut-name=座間味義人 kn-aut-sei=座間味 kn-aut-mei=義人 aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=2 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=3 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=4 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=77 end-page=79 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Sj?gren's syndrome kn-title=シェーグレン症候群 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsumotoYoshinori en-aut-sei=Matsumoto en-aut-mei=Yoshinori kn-aut-name=松本佳則 kn-aut-sei=松本 kn-aut-mei=佳則 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Kidney, Diabetes and Endocrine Diseases, Okayama University Hospital kn-affil=岡山大学病院　腎臓・糖尿病・内分泌内科 en-keyword=シェーグレン症候群 kn-keyword=シェーグレン症候群 en-keyword=疫学 kn-keyword=疫学 en-keyword=治療 kn-keyword=治療 en-keyword=特定疾患 kn-keyword=特定疾患 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=74 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Acquired idiopathic generalized anhidrosis (AIGA) kn-title=特発性後天性全身性無汗症 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KawakamiYoshio en-aut-sei=Kawakami en-aut-mei=Yoshio kn-aut-name=川上佳夫 kn-aut-sei=川上 kn-aut-mei=佳夫 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Dermatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　皮膚科学 en-keyword=コリン性蕁麻疹 kn-keyword=コリン性蕁麻疹 en-keyword=ステロイドパルス kn-keyword=ステロイドパルス en-keyword=機能性高体温症 kn-keyword=機能性高体温症 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=2 article-no= start-page=69 end-page=73 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of immune checkpoint inhibitor-associated colitis treated with infliximab kn-title=インフリキシマブが著効した免疫関連有害事象大腸炎の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary. en-copyright= kn-copyright= en-aut-name=IwamuroMasaya en-aut-sei=Iwamuro en-aut-mei=Masaya kn-aut-name=岩室雅也 kn-aut-sei=岩室 kn-aut-mei=雅也 aut-affil-num=1 ORCID= en-aut-name=HiraokaSakiko en-aut-sei=Hiraoka en-aut-mei=Sakiko kn-aut-name=平岡佐規子 kn-aut-sei=平岡 kn-aut-mei=佐規子 aut-affil-num=2 ORCID= en-aut-name=OtsukaMotoyuki en-aut-sei=Otsuka en-aut-mei=Motoyuki kn-aut-name=大塚基之 kn-aut-sei=大塚 kn-aut-mei=基之 aut-affil-num=3 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院　消化器内科 affil-num=2 en-affil=Inflammatory Bowel Disease Center, Okayama University Hospital kn-affil=岡山大学病院　炎症性腸疾患センター affil-num=3 en-affil=Department of Gastroenterology and Hepatology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University 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en-subject= kn-subject= en-title=Elucidation of cardiovascular disease mechanisms and development of innovative therapies kn-title=循環器疾患の病態解明と治療方法の開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YuasaShinsuke en-aut-sei=Yuasa en-aut-mei=Shinsuke kn-aut-name=湯浅慎介 kn-aut-sei=湯浅 kn-aut-mei=慎介 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Cardiovascular, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　循環器内科学 en-keyword=循環器疾患 kn-keyword=循環器疾患 en-keyword=基礎研究 kn-keyword=基礎研究 en-keyword=創薬 kn-keyword=創薬 en-keyword=幹細胞 kn-keyword=幹細胞 en-keyword=人工知能 kn-keyword=人工知能 END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=1 article-no= start-page=7 end-page=11 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Intraoperative diagnosis of brain tumors using fluorescent probes 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dt-pub-year=2024 dt-pub=20240331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Practical BIZEN Device Design Course Activity Report in Fiscal 2023 kn-title=2023年度次世代医療機器開発人材育成プログラム　BIZENデバイスデザインコースの取り組み en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KORENAGAToshio en-aut-sei=KORENAGA en-aut-mei=Toshio kn-aut-name=伊永俊雄 kn-aut-sei=伊永 kn-aut-mei=俊雄 aut-affil-num=1 ORCID= en-aut-name=UCHIDADaisuke en-aut-sei=UCHIDA en-aut-mei=Daisuke kn-aut-name=内田大輔 kn-aut-sei=内田 kn-aut-mei=大輔 aut-affil-num=2 ORCID= en-aut-name=KISHIMOTOToshio en-aut-sei=KISHIMOTO en-aut-mei=Toshio kn-aut-name=岸本俊夫 kn-aut-sei=岸本 kn-aut-mei=俊夫 aut-affil-num=3 ORCID= en-aut-name=SENGOKUYoshinari en-aut-sei=SENGOKU en-aut-mei=Yoshinari kn-aut-name=仙石喜也 kn-aut-sei=仙石 kn-aut-mei=喜也 aut-affil-num=4 ORCID= en-aut-name=OKAHisao en-aut-sei=OKA en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=5 ORCID= en-aut-name=TSUZUKITsuneaki 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Medicine, Okayama University Hospital kn-affil=岡山大学病院 新医療研究開発センター affil-num=7 en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域 affil-num=8 en-affil=Organization for Research Strategy and Development, Okayama University kn-affil=岡山大学 研究推進機構 END start-ver=1.4 cd-journal=joma no-vol=21 cd-vols= no-issue= article-no= start-page=31 end-page=38 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=塚本先生の論文に学ぶ en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本論文では，塚本千秋先生がこれまで相談室紀要に執筆された論文をレビューした。それぞれの論文から，@クライエント・セラピスト双方に流れる時間を意識する重要性，A DV被害者という困難なケースに相対する際に構造を安定させる不断の努力が必要であること，B事例報告において各回のセッションを記述する作業それ自体が臨床研修として有用であること，C助言を行う前にまず目の前のクライエントその人の思いに焦点を当てること，D面接の中で思いついた介入を十分吟味すること，E試行カウンセリングの臨床現場とは異なる特殊性，F精神科医療の動向に，我々心理臨床家が注意を払う必要性，G不祥事や倫理的問題を自分ごととして考える重要性，H研修における協議が活発になるような架空事例作成の工夫，I14回の講義に通底する先生の思想や哲学など，を学ぶことができる。 en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=住岡恭子 kn-aut-sei=住岡 kn-aut-mei=恭子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学学術研究院社会文化科学学域 en-keyword=塚本千秋先生 kn-keyword=塚本千秋先生 en-keyword=精神医学 kn-keyword=精神医学 en-keyword=臨床心理学 kn-keyword=臨床心理学 END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=17 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20221225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=心理職養成と精神医学教育―迷いは深まるばかりなり― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　心理職を志す学生に精神医学を教えることは，自明なことのように思える。しかし，精神医学は世間の人が想像するほど安定した学問ではなく，またその実践としての精神科臨床も，定式化されているとは言えない。これを教育という視点で考えると，教える人間が「学問として流動的」「実践には疑問も多い」などと言えば，すでにこの領域に関心を持っている学生には有益かもしれないが，それほどでもない学生は不安を抱くだろう。「それなら，最低限たしかなことだけ教えればよい」と読者は思うだろうが，それができるなら苦労はしない。本稿では，これまで筆者が実践してきた講義の概要を紹介しながら，筆者の課題意識を検討する。 en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塚本千秋 kn-aut-sei=塚本 kn-aut-mei=千秋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学学術研究院社会文化科学領域 en-keyword=心理職養成 kn-keyword=心理職養成 en-keyword=臨床心理士 kn-keyword=臨床心理士 en-keyword=公認心理師 kn-keyword=公認心理師 en-keyword=精神医学教育 kn-keyword=精神医学教育 END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=43 end-page=48 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=潜在的不登校生徒における友人関係認知の特徴について en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究の目的は，主として対人関係認知スタイルと潜在的不登校の関係を明らかにし，その学校生活意識の特徴を把握することであった。1,129名(１年生男女186名，181名，２年生男女172名，199名，３年生男女151名，177名）の登校している中学生に対し，対人関係認知，自己肯定感，学校生活調査を実施したところ，他者を否定的に認知し，かつ他者の自分に対する思いも否定的であると認知している個人は，@学校嫌い意識を持ち，A新学期の始まる日や月曜日には学校へ行きたくないと思っており，早退をすることが多い。B学校行事，体育が嫌いであり，C学校で打ち込んでいるものはない，という学校生活意識を有していることが明らかとなった。 en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=山縣成美 kn-aut-sei=山縣 kn-aut-mei=成美 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=東條光彦 kn-aut-sei=東條 kn-aut-mei=光彦 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=重井医学研究所附属病院 affil-num=2 en-affil= kn-affil=岡山大学大学院教育学研究科 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=183 end-page=185 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Mental health and social issues : How to achieve multi-layered and sustainable support : The 51st Annual Meeting/The 36th Seminar of the Japanese Society of Psychosomatic Obstetrics and Gynecology kn-title=メンタルヘルスと社会：多層的で持続可能な支援に向けて― 第51回日本女性心身医学会学術集会／第36回日本女性心身医学会研修会を終えて― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NakatsukaMikiya en-aut-sei=Nakatsuka en-aut-mei=Mikiya kn-aut-name=中塚幹也 kn-aut-sei=中塚 kn-aut-mei=幹也 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Health Sciences, Okayama University, The Reproduction Center, Okayama University Hospital, Okayama University Gender Clinic kn-affil=岡山大学学術研究院保健学域，岡山大学病院　リプロダクションセンター，岡山大学ジェンダークリニック END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=181 end-page=182 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 95th Annual Meeting of the Japanese Tissue Culture Association kn-title=日本組織培養学会第95回大会報告 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SakaguchiMasakiyo en-aut-sei=Sakaguchi en-aut-mei=Masakiyo kn-aut-name=阪口政清 kn-aut-sei=阪口 kn-aut-mei=政清 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Cell Biology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　細胞生物学 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=179 end-page=180 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 47th Annual Meeting of the Japan Society of Women's Nutrition and Metabolism kn-title=第47回日本女性栄養・代謝学会学術集会開催報告 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MasuyamaHisashi en-aut-sei=Masuyama en-aut-mei=Hisashi kn-aut-name=増山寿 kn-aut-sei=増山 kn-aut-mei=寿 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Obstetrics and Gynecology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　産科・婦人科学 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=175 end-page=178 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 96th Annual Meeting of the Japanese Orthopaedic Association kn-title=第96回日本整形外科学会学術総会を開催して en-subtitle= kn-subtitle= en-abstract= kn-abstract= 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and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　分子医化学 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=172 end-page=173 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Specified clinical trials kn-title=特定臨床研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SakuraiJun en-aut-sei=Sakurai en-aut-mei=Jun kn-aut-name=櫻井淳 kn-aut-sei=櫻井 kn-aut-mei=淳 aut-affil-num=1 ORCID= affil-num=1 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil=岡山大学病院　新医療研究開発センター END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=167 end-page=171 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Drug interaction (58. Drug interactions in tacrolimus) kn-title=薬物相互作用（58―タクロリムスの薬物相互作用） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KimuraIkuya en-aut-sei=Kimura en-aut-mei=Ikuya kn-aut-name=木村郁哉 kn-aut-sei=木村 kn-aut-mei=郁哉 aut-affil-num=1 ORCID= en-aut-name=HamanoHirofumi en-aut-sei=Hamano en-aut-mei=Hirofumi kn-aut-name=濱野裕章 kn-aut-sei=濱野 kn-aut-mei=裕章 aut-affil-num=2 ORCID= en-aut-name=KajizonoMakoto en-aut-sei=Kajizono en-aut-mei=Makoto kn-aut-name=鍛治園誠 kn-aut-sei=鍛治園 kn-aut-mei=誠 aut-affil-num=3 ORCID= en-aut-name=ZamamiYoshito en-aut-sei=Zamami en-aut-mei=Yoshito kn-aut-name=座間味義人 kn-aut-sei=座間味 kn-aut-mei=義人 aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=2 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=3 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 affil-num=4 en-affil=Department of Pharmacy, Okayama University Hospital kn-affil=岡山大学病院　薬剤部 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=158 end-page=166 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effects of interagency collaboration in contagious disease control for COVID-19 : Okayama COVID-19 cluster Intervention Team (OCIT) kn-title=COVID-19に対する感染管理活動を通して得られた官民学連携の協働体制― 岡山県クラスター対策班（OCIT）の取り組み― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakahashiKazutaka en-aut-sei=Takahashi en-aut-mei=Kazutaka kn-aut-name=橋一剛 kn-aut-sei=橋 kn-aut-mei=一剛 aut-affil-num=1 ORCID= en-aut-name=TakahashiYukari en-aut-sei=Takahashi en-aut-mei=Yukari kn-aut-name=橋友香里 kn-aut-sei=橋 kn-aut-mei=友香里 aut-affil-num=2 ORCID= en-aut-name=IchimuraYasunori en-aut-sei=Ichimura en-aut-mei=Yasunori kn-aut-name=市村康典 kn-aut-sei=市村 kn-aut-mei=康典 aut-affil-num=3 ORCID= en-aut-name=UnoKenya en-aut-sei=Uno en-aut-mei=Kenya kn-aut-name=宇野絢哉 kn-aut-sei=宇野 kn-aut-mei=絢哉 aut-affil-num=4 ORCID= en-aut-name=ImajoSato en-aut-sei=Imajo en-aut-mei=Sato kn-aut-name=今城沙都 kn-aut-sei=今城 kn-aut-mei=沙都 aut-affil-num=5 ORCID= en-aut-name=MitsuiSatoshi en-aut-sei=Mitsui en-aut-mei=Satoshi kn-aut-name=光井聡 kn-aut-sei=光井 kn-aut-mei=聡 aut-affil-num=6 ORCID= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=7 ORCID= en-aut-name=YorifujiTakashi en-aut-sei=Yorifuji en-aut-mei=Takashi kn-aut-name=頼藤貴志 kn-aut-sei=頼藤 kn-aut-mei=貴志 aut-affil-num=8 ORCID= affil-num=1 en-affil=Risk Management Office for COVID-19, Department of Health and Medical Care, Okayama Prefectural Government kn-affil=岡山県保健医療部新型コロナウイルス感染症対策室 affil-num=2 en-affil=Department of Intractable Diseases, Health Service Bureau, Ministry of Health, Labour and Welfare kn-affil=厚生労働省健康局難病対策課 affil-num=3 en-affil=Bureau of International Health Cooperation, National Center for Global Health and Medicine kn-affil=国立国際医療研究センター国際医療協力局 affil-num=4 en-affil=Risk Management Office for COVID-19, Department of Health and Medical Care, Okayama Prefectural Government kn-affil=岡山県保健医療部新型コロナウイルス感染症対策室 affil-num=5 en-affil=Risk Management Office for COVID-19, Department of Health and Medical Care, Okayama Prefectural Government kn-affil=岡山県保健医療部新型コロナウイルス感染症対策室 affil-num=6 en-affil=Okayama Prefecture Mimasaka Public Health Center kn-affil=岡山県美作保健所 affil-num=7 en-affil=Department of Health and Medical Care, Okayama Prefectura Government kn-affil=岡山県保健医療部 affil-num=8 en-affil=Department of Epidemiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　疫学・衛生学 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=152 end-page=157 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A 4th step of visual art instruction in medical education kn-title=医学における「ビジュアルアート教育」の展開：第４ステップ― 医学教育に必要な“気づき”を与える授業― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=木股敬裕 kn-aut-sei=木股 kn-aut-mei=敬裕 aut-affil-num=1 ORCID= en-aut-name=ObikaMikako en-aut-sei=Obika en-aut-mei=Mikako kn-aut-name=小比賀美香子 kn-aut-sei=小比賀 kn-aut-mei=美香子 aut-affil-num=2 ORCID= en-aut-name=KuboTakuya en-aut-sei=Kubo en-aut-mei=Takuya kn-aut-name=久保卓也 kn-aut-sei=久保 kn-aut-mei=卓也 aut-affil-num=3 ORCID= en-aut-name=OtsukaMasumi en-aut-sei=Otsuka en-aut-mei=Masumi kn-aut-name=大塚益美 kn-aut-sei=大塚 kn-aut-mei=益美 aut-affil-num=4 ORCID= en-aut-name=OkamotoYuko en-aut-sei=Okamoto en-aut-mei=Yuko kn-aut-name=岡本裕子 kn-aut-sei=岡本 kn-aut-mei=裕子 aut-affil-num=5 ORCID= en-aut-name=FukutomiKoh en-aut-sei=Fukutomi en-aut-mei=Koh kn-aut-name=福冨幸 kn-aut-sei=福冨 kn-aut-mei=幸 aut-affil-num=6 ORCID= 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dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Retinitis pigmentosa kn-title=網膜色素変性症 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsuoToshihiko en-aut-sei=Matsuo en-aut-mei=Toshihiko kn-aut-name=松尾俊彦 kn-aut-sei=松尾 kn-aut-mei=俊彦 aut-affil-num=1 ORCID= affil-num=1 en-affil=Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Department of Ophthalmology, Okayama University Hospital kn-affil=岡山大学学術研究院ヘルスシステム統合科学学域，岡山大学病院　眼科 en-keyword=網膜色素変性症 kn-keyword=網膜色素変性症 en-keyword=遺伝子パネル kn-keyword=遺伝子パネル en-keyword=人工網膜 kn-keyword=人工網膜 en-keyword=遺伝子治療 kn-keyword=遺伝子治療 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=142 end-page=146 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Systemic amyloidosis : Diagnosis and treatment of transthyretin cardiac amyloidosis 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kn-abstract= en-copyright= kn-copyright= en-aut-name=ArakiMotoo en-aut-sei=Araki en-aut-mei=Motoo kn-aut-name=荒木元朗 kn-aut-sei=荒木 kn-aut-mei=元朗 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Urology, Faculty of Medicine, Dentistry and Pharmaceutical Science, Okayama University kn-affil=岡山大学学術研究院医歯薬学域　泌尿器病態学 en-keyword=腎虚血再灌流障害 kn-keyword=腎虚血再灌流障害 en-keyword=リアルタイムイメージング kn-keyword=リアルタイムイメージング en-keyword=好中球 kn-keyword=好中球 en-keyword=腎移植 kn-keyword=腎移植 END start-ver=1.4 cd-journal=joma no-vol=135 cd-vols= no-issue=3 article-no= start-page=129 end-page=135 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of head and neck reconstruction and procedures learned from patients kn-title=患者が教えてくれた頭頸部再建と手技の開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=木股敬裕 kn-aut-sei=木股 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en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MORIMOTOYoshimasa en-aut-sei=MORIMOTO en-aut-mei=Yoshimasa kn-aut-name=森本芳正 kn-aut-sei=森本 kn-aut-mei=芳正 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=日本における保育とこどもの発達について kn-title=Childcare and Child Development in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MURATAAkiko en-aut-sei=MURATA en-aut-mei=Akiko kn-aut-name=村田亜紀子 kn-aut-sei=村田 kn-aut-mei=亜紀子 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 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kn-title=Prevalence and Treatment of Arrhythmias in Patients With Transthyretin and Light-Chain Cardiac Amyloidosis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MIYAMOTOMasakazu en-aut-sei=MIYAMOTO en-aut-mei=Masakazu kn-aut-name=宮本真和 kn-aut-sei=宮本 kn-aut-mei=真和 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=我が国の高次医療機関における後腹膜線維症の臨床的特徴 kn-title=Clinical Characteristics of Retroperitoneal Fibrosis Patients at a Tertiary Hospital in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ANDOMiho en-aut-sei=ANDO en-aut-mei=Miho kn-aut-name=安藤美穂 kn-aut-sei=安藤 kn-aut-mei=美穂 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=内側半月板後根断裂に対するpullout修復術において、後方アンカリングの追加は内側半月板の後方逸脱を改善させる：後ろ向き研究 kn-title=Concomitant posterior anchoring further reduces posterior meniscal extrusion during pullout repair of medial meniscus posterior root tears: a retrospective study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=XUEHAOWEI en-aut-sei=XUE en-aut-mei=HAOWEI kn-aut-name=薛昊嵬 kn-aut-sei=薛 kn-aut-mei=昊嵬 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=高転移性トリプルネガティブ乳癌細胞では鉄代謝が制限され、鉄キレート剤の治療標的となり得る kn-title=Highly Metastatic Subpopulation of TNBC Cells Has Limited Iron Metabolism and Is a Target of Iron Chelators en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WANGYUZE en-aut-sei=WANG en-aut-mei=YUZE kn-aut-name=王宇沢 kn-aut-sei=王 kn-aut-mei=宇沢 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=術中低体温における麻酔導入後血糖の影響について kn-title=The Effect of Postinduction Blood Glucose on Intraoperative Hypothermia en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SHENZHANGTIAN en-aut-sei=SHEN en-aut-mei=ZHANGTIAN kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=PD-1阻害は、Egfr変異陽性肺癌においてAd-SGE-REICにより誘導されるCD8+T細胞依存性抗腫瘍免疫を増強する kn-title=PD-1 blockade augments CD8+ T cell dependent antitumor immunity triggered by Ad-SGE-REIC in Egfr-mutant lung cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NAKASUKATakamasa en-aut-sei=NAKASUKA en-aut-mei=Takamasa kn-aut-name=中須賀崇匡 kn-aut-sei=中須賀 kn-aut-mei=崇匡 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=子宮内膜癌において転移巣の分子学的特徴はより予後を反映する kn-title=Molecular Characteristics of Metastatic Lesions Have Superior Prognositc Impact on Endometrial Cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OKAMOTOKazuhiro en-aut-sei=OKAMOTO en-aut-mei=Kazuhiro kn-aut-name=岡本和浩 kn-aut-sei=岡本 kn-aut-mei=和浩 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=SLE患者における飲酒と倦怠感との関連:LUNAコホートからの横断研究 kn-title=Association of alcohol consumption and fatigue in SLE: A cross-sectional study from Lupus Registry of Nationwide Institution (LUNA) cohort en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KATAYAMAYu en-aut-sei=KATAYAMA en-aut-mei=Yu kn-aut-name=片山祐 kn-aut-sei=片山 kn-aut-mei=祐 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラット脳虚血モデルに対するヒト骨髄由来加工間葉系幹細胞（SB623）の脳内移植とランニングホイールを用いた自発運動による治療の相乗効果 kn-title=Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YABUNOSatoru en-aut-sei=YABUNO en-aut-mei=Satoru kn-aut-name=藪野諭 kn-aut-sei=藪野 kn-aut-mei=諭 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=RNA編集は潰瘍性大腸炎関連発癌を予測する有用なバイオマーカーである kn-title=RNA Editing is a Valuable Biomarker for Predicting Carcinogenesis in Ulcerative Colitis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TAKAHASHIKazutaka en-aut-sei=TAKAHASHI en-aut-mei=Kazutaka kn-aut-name=橋一剛 kn-aut-sei=橋 kn-aut-mei=一剛 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ヒト骨髄由来間葉系幹細胞脳内移植は脳梗塞モデルラットに治療効果をもたらす kn-title=Transplantation of modified human bone marrow-derived stromal cells affords therapeutic effects on cerebral ischemia in rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KAWAUCHISatoshi en-aut-sei=KAWAUCHI en-aut-mei=Satoshi kn-aut-name=河内哲 kn-aut-sei=河内 kn-aut-mei=哲 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肝細胞癌の上皮間葉転換と幹細胞性の新規調節因子: SPRED2 kn-title=SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=GAOTONG en-aut-sei=GAO en-aut-mei=TONG kn-aut-name=高桐 kn-aut-sei=高 kn-aut-mei=桐 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=臼蓋関節唇の血管内皮増殖因子および神経成長因子の発現は変形性股関節症の疼痛に直接関連する：免疫組織化学染色による検討 kn-title=Expression of Acetabular Labral Vascular Endothelial Growth Factor and Nerve Growth Factor Is Directly Associated with Hip Osteoarthritis Pain: Investigation by Immunohistochemical Staining en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SATOYoshihiro en-aut-sei=SATO en-aut-mei=Yoshihiro kn-aut-name=佐藤嘉洋 kn-aut-sei=佐藤 kn-aut-mei=嘉洋 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=胸腔鏡手術後におけるアセトアミノフェン静注薬定期投与の術後鎮痛効果の検討 kn-title=Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SHIKATANIYoshinobu en-aut-sei=SHIKATANI en-aut-mei=Yoshinobu kn-aut-name=鹿谷芳伸 kn-aut-sei=鹿谷 kn-aut-mei=芳伸 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=造血幹細胞由来制御性T細胞は移植後シクロホスファミドによる良好なBリンパ球新生の長期維持に重要である kn-title=Hematopoietic stem cell-derived Tregs are essential for maintaining favorable B cell lymphopoiesis following posttransplant cyclophosphamide en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SUMIIYuichi en-aut-sei=SUMII en-aut-mei=Yuichi kn-aut-name=住居優一 kn-aut-sei=住居 kn-aut-mei=優一 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol=291 cd-vols= no-issue=6 article-no= start-page=1119 end-page=1130 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231020 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes en-subtitle= kn-subtitle= en-abstract= kn-abstract=During the replication of viral genomes, RNA viruses produce double-stranded RNA (dsRNA), through the activity of their RNA-dependent RNA polymerases (RdRps) as viral replication intermediates. Recognition of viral dsRNA by host pattern recognition receptors ? such as retinoic acid-induced gene-I (RIG-I)-like receptors and Toll-like receptor 3 ? triggers the production of interferon (IFN)-β via the activation of IFN regulatory factor (IRF)-3. It has been proposed that, during the replication of viral genomes, each of RIG-I and melanoma differentiation-associated gene 5 (MDA5) form homodimers for the efficient activation of a downstream signalling pathway in host cells. We previously reported that, in the non-neoplastic human hepatocyte line PH5CH8, the RdRp NS5B derived from hepatitis C virus (HCV) could induce IFN-β expression by its RdRp activity without the actual replication of viral genomes. However, the exact mechanism by which HCV NS5B produced IFN-β remained unknown. In the present study, we first showed that NS5B derived from another Flaviviridae family member, GB virus B (GBV-B), also possessed the ability to induce IFN-β in PH5CH8 cells. Similarly, HCV NS5B, but not its G317V mutant, which lacks RdRp activity, induced the dimerization of MDA5 and subsequently the activation of IRF-3. Interestingly, immunofluorescence analysis showed that HCV NS5B produced dsRNA. Like HCV NS5B, GBV-B NS5B also triggered the production of dsRNA and subsequently the dimerization of MDA5. Taken together, our results show that HCV NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes in human hepatocytes. en-copyright= kn-copyright= en-aut-name=DansakoHiromichi en-aut-sei=Dansako en-aut-mei=Hiromichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IkedaMasanori en-aut-sei=Ikeda en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AriumiYasuo en-aut-sei=Ariumi en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TogashiYosuke en-aut-sei=Togashi en-aut-mei=Yosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KatoNobuyuki en-aut-sei=Kato en-aut-mei=Nobuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Division of Biological Information Technology, Joint Research Center for Human Retrovirus Infection, Kagoshima University kn-affil= affil-num=3 en-affil=Management Department of Biosafety, Laboratory Animal, and Pathogen Bank, National Institute of Infectious Diseases kn-affil= affil-num=4 en-affil=Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=double-stranded RNA kn-keyword=double-stranded RNA en-keyword=hepatitis C virus kn-keyword=hepatitis C virus en-keyword=innate immunity kn-keyword=innate immunity en-keyword=RIG-I-like receptor kn-keyword=RIG-I-like receptor en-keyword=RNA virus kn-keyword=RNA virus END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ACTH処置ラットにおける5-HT2A受容体を介したwet-dog shake行動に対するモノアミン再取り込み阻害剤の影響 kn-title=Effects of monoamine reuptake inhibitors on wet-dog shakes mediated by 5-HT2A receptors in ACTH-treated rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KawakamiYasuhiro en-aut-sei=Kawakami en-aut-mei=Yasuhiro kn-aut-name=川上恭弘 kn-aut-sei=川上 kn-aut-mei=恭弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=血管内皮成長因子(VEGF)産生細胞のカプセル化脳内移植は脳虚血に対して神経保護と血管形成効果を持つ kn-title=Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YanoAkimasa en-aut-sei=Yano en-aut-mei=Akimasa kn-aut-name=矢野昭正 kn-aut-sei=矢野 kn-aut-mei=昭正 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=犬実験モデルを用いた慢性の圧負荷を伴う右心不全に対するポンプを用いない膜型人工肺による体外循環(ECMO)補助の血行動態に及ぼす効果 kn-title=Hemodynamic effects of pumpless extracorporeal membrane oxygenation (ECMO) support for chronically pressure-overloaded right heart failure in a canine experimental model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TamesueKiyokazu en-aut-sei=Tamesue en-aut-mei=Kiyokazu kn-aut-name=爲季清和 kn-aut-sei=爲季 kn-aut-mei=清和 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=閉塞性黄疸におけるTLR4発現増強を介したLPSに対する感受性亢進 : 消化管由来のHGFによる肝細胞防御 kn-title=Obstructive jaundice increases sensitivity to lipopolysaccharide via TLR4 upregulation : possible involvement in gut-derived hepatocyte growth factor-protection of hepatocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MiyasoHideaki en-aut-sei=Miyaso en-aut-mei=Hideaki kn-aut-name=宮宗秀明 kn-aut-sei=宮宗 kn-aut-mei=秀明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラット皮膚移植モデルにおけるPGE2の免疫抑制におけるプロスタグランジンE2受容体の解析 kn-title=Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=FujimotoYoshimi en-aut-sei=Fujimoto en-aut-mei=Yoshimi kn-aut-name=藤本善三 kn-aut-sei=藤本 kn-aut-mei=善三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Reboxetineとfluoxetineの急性投与によりラット前脳に誘導されるFos蛋白発現の対比 : 抗うつ効果の神経解剖学的基盤 kn-title=Contrasting Fos expression induced by acute reboxetine and fluoxetine in the rat forebrain : neuroanatomical substrates for the antidepressant effect en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MiyataShinji en-aut-sei=Miyata en-aut-mei=Shinji kn-aut-name=宮田信司 kn-aut-sei=宮田 kn-aut-mei=信司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END