start-ver=1.4 cd-journal=joma no-vol=239 cd-vols= no-issue= article-no= start-page=113260 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Helical X-ray tube trajectory estimation via image noise analysis for enhanced CT dosimetry en-subtitle= kn-subtitle= en-abstract= kn-abstract=Information on the helical trajectory of the X-ray tube is necessary for accurate dose evaluation during computed tomography (CT). We aimed to propose a methodology for analyzing the trajectory of the X-ray tube. The novelty of this paper is that the incident direction of X-rays is estimated from the standard deviation (SD) distribution. The X-ray incident direction for each slice was analyzed using a distribution function of SD values, in which the analysis regions were placed in the air region. Then, the helical trajectory of the CT scan was estimated by fitting a three-dimensional helical function to the analyzed data. The robustness of our algorithm was verified through phantom studies: the analyzed X-ray incident directions were compared with instrumental log data, in which cylindrical polyoxymethylene resin phantoms and a whole-body phantom were scanned. Chest CT scanning was mimicked, in which the field of view (FOV) was set at the lung region. The procedure for analyzing the X-ray incident direction was applicable to cylindrical phantoms regardless of the phantom size. In contrast, in the case of the whole-body phantom, although it was possible to apply our procedure to the chest and abdomen regions, the shoulder slices were inappropriate to analyze. Therefore, the helical trajectory was determined based on chest and abdominal CT images. The accuracy in X-ray incident direction analysis was evaluated to be 7.5‹. In conclusion, we have developed an algorithm to estimate a three-dimensional helical trajectory that can be used for dose measurements and simulations. en-copyright= kn-copyright= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakegamiKazuki en-aut-sei=Takegami en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YamashitaKazuta en-aut-sei=Yamashita en-aut-mei=Kazuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=HigashinoKosaku en-aut-sei=Higashino en-aut-mei=Kosaku kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MorimotoShinichi en-aut-sei=Morimoto en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=KonishiTakeshi en-aut-sei=Konishi en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=MakiMotochika en-aut-sei=Maki en-aut-mei=Motochika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=2 en-affil=Department of Radiological Technology, Yamaguchi University Hospital kn-affil= affil-num=3 en-affil=Faculty of Health Sciences, Kobe Tokiwa University kn-affil= affil-num=4 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=6 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=7 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=8 en-affil=Department of Orthopedics, School of Medicine, Tokushima University kn-affil= affil-num=9 en-affil=Shikoku Medical Center for Children and Adults kn-affil= affil-num=10 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=11 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=12 en-affil=MEDITEC JAPAN Co., Ltd., Yamaguchi Kosan Bld. kn-affil= affil-num=13 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=X-ray medical diagnosis kn-keyword=X-ray medical diagnosis en-keyword=Helical CT scan kn-keyword=Helical CT scan en-keyword=CT image kn-keyword=CT image en-keyword=X-ray incident direction kn-keyword=X-ray incident direction en-keyword=Helical trajectory kn-keyword=Helical trajectory en-keyword=Radiation dose measurement kn-keyword=Radiation dose measurement END start-ver=1.4 cd-journal=joma no-vol=238 cd-vols= no-issue= article-no= start-page=113243 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202601 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Bone-enhanced high contrast X-ray images derived from attenuation estimation related to ultra-low energy X-rays ? An application of an energy-resolving photon-counting detector (ERPCD) en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose: X-ray diagnosis in medicine is often used for bone diagnosis based on qualitative observation analysis. However, there are often cases where the contrast of bones is reduced because of the existence of soft-tissues, making it difficult to accurately diagnose the bone conditions. Although the algorithm for bone extraction images was proposed using an energy-resolving photon-counting detector (ERPCD), this algorithm can depict goneh bone material (such as hydroxyapatite under the assumption), and it is difficult to adequately depict other components. The purpose of this study is to develop an algorithm for bone-enhanced high-contrast images that can be virtually represented by the attenuation of extremely low-energy X-rays without making any special assumptions.
Methods: High-contrast images were virtually generated based on the attenuation rate of ultra-low energy X-rays. It was determined by fitting the mass attenuation coefficient (ƒÊ/ƒÏ) curve to the X-ray attenuation values (ƒÊt values) measured at middle (30?40 keV) and high (40?60 keV) energy windows, and extrapolating the ƒÊt values to those for the low energy region (E = 5?20 keV). When performing the extrapolation, the effective atomic number (Zeff ) of the object was taken into consideration. The methodology was validated by simulating X-ray projections using a digital human body phantom. The frequency of correspondence between the pixel values in the high-contrast image and the Zeff image was analyzed for each pixel.
Results: We succeeded in creating virtual high-contrast X-ray images that reflect the image contrast of monochromatic X-rays of 5?20 keV. It was confirmed that the pixel values in the high-contrast image corresponding to an Zeff = 7.5 (soft-tissue) were completely separated from those corresponding to an Zeff = 9 (bone). The optimization of the energy related to the high contrast images was performed based on the contrast-to-noise ratio (CNR) analysis. The high contrast image with 10 keV showed a good CNR value.
Conclusions: Based on the analysis of the attenuation information of middle and high-energy X-rays measured by ERPCDs, we succeeded in creating a novel algorithm that can generate a virtual monochromatic image with high contrast. en-copyright= kn-copyright= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HabaTomonobu en-aut-sei=Haba en-aut-mei=Tomonobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KanazawaYuki en-aut-sei=Kanazawa en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YamamotoShuichiro en-aut-sei=Yamamoto en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=2 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=3 en-affil=Faculty of Health Sciences, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=5 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=6 en-affil=Faculty of Health Sciences, Kobe Tokiwa University kn-affil= affil-num=7 en-affil=Faculty of Radiological Technology, School of Medical Science, Fujita Health University kn-affil= affil-num=8 en-affil=Faculty of Life Science, Kumamoto University kn-affil= affil-num=9 en-affil=JOB CORPORATION kn-affil= affil-num=10 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=Medical X-ray diagnosis kn-keyword=Medical X-ray diagnosis en-keyword=Photon-counting detector kn-keyword=Photon-counting detector en-keyword=High contrast image kn-keyword=High contrast image en-keyword=Virtual monochromatic image kn-keyword=Virtual monochromatic image en-keyword=Effective atomic number kn-keyword=Effective atomic number en-keyword=Ultra-low energy image kn-keyword=Ultra-low energy image END start-ver=1.4 cd-journal=joma no-vol=239 cd-vols= no-issue= article-no= start-page=113237 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2026 dt-pub=202602 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Counting-loss correction procedure of X-ray imaging detectors with consideration for the effective atomic number of biological objects en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is necessary to correct counting loss caused by the pulse pile-up effect and dead time when using energy-resolving photon-counting detectors (ERPCDs) under ghigh-counting-rateh conditions in medical and/or industrial settings. We aimed to develop a novel counting-loss correction procedure in which biological objects having effective atomic numbers (Zeff values) of 6.5?13.0 are measured with polychromatic X-rays. To correct for counting loss, such a procedure must theoretically estimate the count value of an ideal X-ray spectrum without counting loss. In this study, we estimated the ideal X-ray spectrum by focusing on the following two points: (1) the X-ray attenuation in an object (Zeff values of 6.5?13.0) and (2) the detector response. Virtual materials having intermediate atomic numbers between 6.5 and 13.0 were generated by using a mixture of polymethylmethacrylate (PMMA, Zeff = 6.5) and aluminum (Al, Zeff = 13.0). We then constructed an algorithm that can perform the counting-loss correction based on the objectfs true Zeff value. To demonstrate the applicability of our procedure, we analyzed investigational objects consisting of PMMA and Al using a prototype ERPCD system. A fresh fish sample was also analyzed. The Zeff values agree with the theoretical values within an accuracy of Zeff }1. In conclusion, we have developed a highly accurate procedure for correcting counting losses for the quantitative X-ray imaging of biological objects. en-copyright= kn-copyright= en-aut-name=KimotoNatsumi en-aut-sei=Kimoto en-aut-mei=Natsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishigamiRina en-aut-sei=Nishigami en-aut-mei=Rina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KobayashiDaiki en-aut-sei=Kobayashi en-aut-mei=Daiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MaedaTatsuya en-aut-sei=Maeda en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AsaharaTakashi en-aut-sei=Asahara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GotoSota en-aut-sei=Goto en-aut-mei=Sota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KanazawaYuki en-aut-sei=Kanazawa en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KatsumataAkitoshi en-aut-sei=Katsumata en-aut-mei=Akitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YamamotoShuichiro en-aut-sei=Yamamoto en-aut-mei=Shuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HayashiHiroaki en-aut-sei=Hayashi en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University kn-affil= affil-num=2 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=3 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=4 en-affil=Graduate School of Medical Sciences, Kanazawa University kn-affil= affil-num=5 en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University kn-affil= affil-num=6 en-affil=Faculty of Health Science, Kobe Tokiwa University kn-affil= affil-num=7 en-affil=Faculty of Life Science, Kumamoto University kn-affil= affil-num=8 en-affil=Oral Radiology and Artificial Intelligence, Asahi University kn-affil= affil-num=9 en-affil=JOB CORPORATION kn-affil= affil-num=10 en-affil=College of Transdisciplinary Sciences for Innovation, Kanazawa University kn-affil= en-keyword=Photon-counting detector kn-keyword=Photon-counting detector en-keyword=Pulse pile-up kn-keyword=Pulse pile-up en-keyword=Dead time kn-keyword=Dead time en-keyword=Counting-loss correction kn-keyword=Counting-loss correction en-keyword=Charge-sharing effect kn-keyword=Charge-sharing effect en-keyword=Effective atomic number kn-keyword=Effective atomic number END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•«ãŠ{“´‰Š‚ɑ΂·‚é“àŽ‹‹¾‰º•›•@oŽèp‚¨‚æ‚ÑŽ•‰ÈŽ¡—Â̎¡—ÃŒø‰Ê‚ÉŠÖ‚·‚é—Õ°“IŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TOKUSHIGEYu en-aut-sei=TOKUSHIGE en-aut-mei=Yu kn-aut-name=úºd˜Ð kn-aut-sei=úºd kn-aut-mei=˜Ð aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‹¸³Ž•‰ÈŽ¡—Âɂ¨‚¯‚éƒZƒ‹ƒtƒPƒA‚ɑ΂·‚鎩ŒÈŒø—ÍŠ´‘ª’èŽÚ“x‚ÌŠJ”­‚¨‚æ‚ÑM—Š«E‘Ó–«‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YAMAJIKana en-aut-sei=YAMAJI en-aut-mei=Kana kn-aut-name=ŽR’n‰Á“Þ kn-aut-sei=ŽR’n kn-aut-mei=‰Á“Þ aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Œûo•ÛŒ’s“®AŒ’NM”Oƒ‚ƒfƒ‹A‚¨‚æ‚Ñâ‘ΓIƒŠƒXƒN‰ñ”ð“x‚ª“ú–{‚Ì‘åŠw¶‚Ì’èŠú“I‚ÈŽ•‰ÈŒ’fŽóf‚̈ӎu‚É‹y‚Ú‚·‰e‹¿‚ɂ‚¢‚ÄF‰¡’fŒ¤‹† kn-title=The Impact of Oral Health Behaviors, Health Belief Model, and Absolute Risk Aversion on the Willingness of Japanese University Students to Undergo Regular Dental Check-Ups: A Cross-Sectional Study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SUMITAIchiro en-aut-sei=SUMITA en-aut-mei=Ichiro kn-aut-name=Šp“cˆÉ’m˜Y kn-aut-sei=Šp“c kn-aut-mei=ˆÉ’m˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=œŠi«I‹‰•s³™ù‡‚É‚¨‚¯‚é㉺Š{—¼‘¤¬‰PŽ•”²‹Ž‚𔺂¤‹¸³Ž•‰ÈŽ¡—ªˆô“ª•”ã‹C“¹‚É‹y‚Ú‚·‰e‹¿ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KONKOMegumi en-aut-sei=KONKO en-aut-mei=Megumi kn-aut-name=‹àŒõŒb kn-aut-sei=‹àŒõ kn-aut-mei=Œb aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‚—îŠO—ˆŠ³ŽÒ‚É‚¨‚¯‚錇‘¹•â’ÔŽ•‰ÈŽ¡—Ö@CH•iێ摽—l«ƒXƒRƒA‚¨‚æ‚ÑÛŽæ‰Â”\H•iƒXƒRƒA‚Æ‚ÌŠÖ˜A en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SAKAMOTOKazuki en-aut-sei=SAKAMOTO en-aut-mei=Kazuki kn-aut-name=â–{˜aŠî kn-aut-sei=â–{ kn-aut-mei=˜aŠî aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol=136 cd-vols= no-issue=1 article-no= start-page=33 end-page=36 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exosome kn-title=ƒGƒNƒ\ƒ\[ƒ€ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=EguchiTakanori en-aut-sei=Eguchi en-aut-mei=Takanori kn-aut-name=]ŒûŒ†“¿ kn-aut-sei=]Œû kn-aut-mei=Œ†“¿ aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Dental Pharmacology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠwŠwpŒ¤‹†‰@ˆãŽ•–òŠwˆæ@Ž•‰È–ò—Šw END start-ver=1.4 cd-journal=joma no-vol=155 cd-vols= no-issue= article-no= start-page=105797 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=202311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ruxolitinib altered IFN-ƒÀ induced necroptosis of human dental pulp stem cells during osteoblast differentiation en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objective: This study aimed to evaluate the role of ruxolitinib in the interferon beta (IFN-ƒÀ) mediated osteoblast differentiation using human dental pulp stem cells (hDPSCs).
Design: hDPSCs from five deciduous teeth of healthy patients were stimulated by adding human recombinant IFN-ƒÀ protein (1 or 2 ng/ml) to the osteogenic differentiation induction medium. Substrate formation was determined using Alizarin Red staining, calcium concentration, and osteoblast marker expression levels. Ruxolitinib was used to inhibit the Janus kinase/signal transducers and activators of transcription (JAK-STAT) pathway. Apoptosis was detected using terminal deoxynucleotidyl nick-end labeling (TUNEL) staining, and necroptosis was detected using propidium iodide staining and phosphorylated mixed lineage kinase domain-like protein (pMLKL) expression.
Results: In the IFN-ƒÀ-treated group, substrate formation was inhibited by a reduction in alkaline phosphatase (ALP) expression in a concentration-dependent manner. Although the proliferation potency was unchanged between the IFN-ƒÀ-treated and control groups, the cell number was significantly reduced in the experimental group. TUNEL-positive cell number was not significantly different; however, the protein level of necroptosis markers, interleukin-6 (IL-6) and pMLKL were significantly increased in the substrate formation. Cell number and ALP expression level were improved in the group administered ruxolitinib, a JAK-STAT inhibitor. Additionally, ruxolitinib significantly suppressed IL-6 and pMLKL levels.
Conclusion: Ruxolitinib interfered with the IFN-ƒÀ-mediated necroptosis and osteogenic differentiation via the JAK-STAT pathway. en-copyright= kn-copyright= en-aut-name=TanakaAtsuko en-aut-sei=Tanaka en-aut-mei=Atsuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HayanoSatoru en-aut-sei=Hayano en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NagataMasayo en-aut-sei=Nagata en-aut-mei=Masayo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KosamiTakahiro en-aut-sei=Kosami en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=WangZiyi en-aut-sei=Wang en-aut-mei=Ziyi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KamiokaHiroshi en-aut-sei=Kamioka en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Orthodontics, Okayama University Hospital kn-affil= affil-num=2 en-affil=Department of Orthodontics, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Type-I interferon kn-keyword=Type-I interferon en-keyword=Janus kinase/signal transducers and activators of transcription pathway kn-keyword=Janus kinase/signal transducers and activators of transcription pathway en-keyword=Osteoblast kn-keyword=Osteoblast en-keyword=Necroptosis kn-keyword=Necroptosis en-keyword=Singleton-Merten Syndrome kn-keyword=Singleton-Merten Syndrome END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‹¸³Ž•‰ÈŽ¡—Âɂ¨‚¯‚éƒ{ƒ“ƒfƒBƒ“ƒO–@‚ÌŒˆ’è‚É•K—v‚ȈöŽq‚Ì’Tõ-’PˆêŽ{Ý”ñ–ÓŒŸ€ƒ‰ƒ“ƒ_ƒ€‰»”äŠrŽŽŒ±- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TANIZAKISaori en-aut-sei=TANIZAKI en-aut-mei=Saori kn-aut-name=’Jè¹D kn-aut-sei=’Jè kn-aut-mei=¹D aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=41 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=2022 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Interpretation of the official Japanese translation summary of the gMASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapyh (Updated 2019-2020) kn-title=uMASCC/ISOO Œûo”S–ŒáŠQ‚̃}ƒlƒWƒƒ“ƒg‚ÉŠÖ‚·‚é—Õ°ƒKƒCƒhƒ‰ƒCƒ“i2019-2020‰ü’ù”ÅjvŒöŽ®“ú–{Œê–óŠT—v‚̉ðŽß‚ɂ‚¢‚Ä en-subtitle= kn-subtitle= en-abstract=Adverse events frequently occur with chemotherapy, radiation therapy involving the oral cavity, and hematopoietic stem cell transplantation in cancer treatment. The Multinational Association of Supportive Care in Cancer and the International Society for Oral Oncology (MASCC/ISOO) have developed a systematic review methodology and published a updated version of the gMASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapyh in 2019-2020. In addition, an official Japanese translation of the summary overview was also published. However, because it is an international guideline, some references are made to unapproved drugs or off-label use in Japan. In addition, some parts of the summary outline do not convey the intent derived from the original text. This paper introduces the contents of the revised guideline and details the contents of the summary overview of the guideline with the above-mentioned problems in mind. kn-abstract=‚ª‚ñŽ¡—Âɂ¨‚¯‚鉻Šw—Ö@AŒûo‚ðÆŽË–ì‚ÉŠÜ‚Þ•úŽËü—Ö@A‚¨‚æ‚Ñ‘¢ŒŒŠ²×–EˆÚA‚Å‚ÍA—LŠQŽ–Û‚Æ‚µ‚ÄŒûo”S–ŒáŠQ‚ª‚µ‚΂µ‚Δ­¶‚·‚éB‚ª‚ñŽxŽ—Ö@‚Ì‘ÛŠw‰ï‚Å‚ ‚éMultinational Association of Supportive Care in Cancer ‚¨‚æ‚Ñ International Society for Oral Oncology (MASCC/ISOO)‚ÍAƒVƒXƒeƒ}ƒeƒBƒbƒNƒŒƒrƒ…[‚ÌŽè–@‚É‚æ‚èA2019”N‚©‚ç2020”N‚É‚©‚¯‚ÄAuMASCC/ISOO Œûo”S–ŒáŠQ‚̃}ƒlƒWƒƒ“ƒg‚ÉŠÖ‚·‚é—Õ°ƒKƒCƒhƒ‰ƒCƒ“v‚̉ü’ù”Å‚ð”­•\‚µ‚½B‚³‚ç‚ÉA‘Š‡‚ÌŠT—v‚ɂ‚¢‚ÄA“ú–{Œê‚ÌŒöŽ®–|–ó”Å‚à”­•\‚³‚ꂽB‚µ‚©‚µA‘Û“I‚ȃKƒCƒhƒ‰ƒCƒ“‚Å‚ ‚邪ŒÌ‚ÉA“ú–{‚Å‚Ì”ñ³”F–ò‚ ‚é‚¢‚Í“K‰žŠOŽg—p‚ɂ‚¢‚ÄŒ¾‹y‚³‚ê‚Ä‚¢‚é“à—e‚ª‘½‚¢B‚Ü‚½A‘Š‡‚ÌŠT—v‚ÅAŒ´•¶‚É—R—ˆ‚·‚éˆÓ}‚ª“`‚í‚è‚É‚­‚¢‰ÓŠ‚ª‚ ‚éB–{e‚Å‚ÍA‰ü’ù‚³‚ꂽƒKƒCƒhƒ‰ƒCƒ“‚Ì“à—e‚ɂ‚¢‚ÄЉ‚é‚Æ‚Æ‚à‚ÉAãq‚µ‚½–â‘è“_‚ð”O“ª‚ÉAƒKƒCƒhƒ‰ƒCƒ“‚Ì‘Š‡‚ÌŠT—v‚É‹LÚ‚³‚ꂽ“à—e‚ɂ‚¢‚ÄÚq‚µ‚½B en-copyright= kn-copyright= en-aut-name=SOGAYoshihiko en-aut-sei=SOGA en-aut-mei=Yoshihiko kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=1 ORCID= affil-num=1 en-affil=Division of Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@ ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” en-keyword=Œûo”S–ŒáŠQ kn-keyword=Œûo”S–ŒáŠQ en-keyword=Œûo”S–Œ‰Š kn-keyword=Œûo”S–Œ‰Š en-keyword=‚ª‚ñŽ¡—à kn-keyword=‚ª‚ñŽ¡—à en-keyword=ƒKƒCƒhƒ‰ƒCƒ“ kn-keyword=ƒKƒCƒhƒ‰ƒCƒ“ en-keyword=MASCC/ISOO kn-keyword=MASCC/ISOO END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‹¸³Ž•‰ÈŽ¡—Âɂæ‚éãŠ{’†ØŽ•‚ÌŒã•ûˆÚ“®‚ªã‹C“¹‚ÌŒ`‘Ô‚É‚¨‚æ‚Ú‚·‰e‹¿‚ɂ‚¢‚Ä‚ÌŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshidaTomoko en-aut-sei=Ishida en-aut-mei=Tomoko kn-aut-name=Γc•üŽq kn-aut-sei=Γc kn-aut-mei=•üŽq aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol=133 cd-vols= no-issue=3 article-no= start-page=184 end-page=188 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AI research in dentistry and related clinical-study design kn-title=Ž•Šw‚É‚¨‚¯‚éAIŒ¤‹†‚ÆŒ¤‹†ƒfƒUƒCƒ“ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Kimura-OnoAya en-aut-sei=Kimura-Ono en-aut-mei=Aya kn-aut-name=‘å–ìÊ kn-aut-sei=‘å–ì kn-aut-mei=Ê aut-affil-num=1 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name=ŒE–Ø‘ñ’j kn-aut-sei=ŒE–Ø kn-aut-mei=‘ñ’j aut-affil-num=2 ORCID= affil-num=1 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@@Vˆã—ÃŒ¤‹†ŠJ”­ƒZƒ“ƒ^[ affil-num=2 en-affil=Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=‰ªŽR‘åŠwŠwpŒ¤‹†‰@ˆãŽ•–òŠwˆæ@ƒCƒ“ƒvƒ‰ƒ“ƒgĶ•â’ÔŠw en-keyword=lH’m”\ kn-keyword=lH’m”\ en-keyword=Ž•‰È kn-keyword=Ž•‰È en-keyword=—Õ°Œ¤‹†ƒfƒUƒCƒ“ kn-keyword=—Õ°Œ¤‹†ƒfƒUƒCƒ“ END start-ver=1.4 cd-journal=joma no-vol=133 cd-vols= no-issue=3 article-no= start-page=181 end-page=183 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AI in dentistry and clues for starting AI research kn-title=Ž•Šw—̈æ‚É‚¨‚¯‚éAI‚ÆAIŒ¤‹†ŠJŽnŽž‚Ìá•Ç en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KodamaNaoki en-aut-sei=Kodama en-aut-mei=Naoki kn-aut-name=™Z‹Ê’¼‹I kn-aut-sei=™Z‹Ê kn-aut-mei=’¼‹I aut-affil-num=1 ORCID= en-aut-name=SugimotoHikaru en-aut-sei=Sugimoto en-aut-mei=Hikaru kn-aut-name=™–{á© kn-aut-sei=™–{ kn-aut-mei=á© aut-affil-num=2 ORCID= en-aut-name=MinagiShogo en-aut-sei=Minagi en-aut-mei=Shogo kn-aut-name=ŠF–ØÈŒá kn-aut-sei=ŠF–Ø kn-aut-mei=ÈŒá aut-affil-num=3 ORCID= affil-num=1 en-affil=Department of Prosthodontics, Division of Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@@Ž•‰Èi•â’ÔŽ•‰È•”–åj affil-num=2 en-affil=Department of Occlusal and Oral Functional Rehabilitation, Okayama University Graduate School of MedicineC Dentistry and Pharmaceutical Sciences kn-affil=‰ªŽR‘åŠwŠwpŒ¤‹†‰@ˆãŽ•–òŠwˆæ@™ù‡E—L°‹`Ž••â’ÔŠw affil-num=3 en-affil=Department of Occlusal and Oral Functional Rehabilitation, Okayama University Graduate School of MedicineC Dentistry and Pharmaceutical Sciences kn-affil=‰ªŽR‘åŠwŠwpŒ¤‹†‰@ˆãŽ•–òŠwˆæ@™ù‡E—L°‹`Ž••â’ÔŠw en-keyword=lH’m”\ kn-keyword=lH’m”\ en-keyword=Ž•‰È kn-keyword=Ž•‰È en-keyword=™ðš kn-keyword=™ðš END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue= article-no= start-page=11 end-page=27 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211224 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Perceived Stress of Students under the COVID-19 Crisis. kn-title=VŒ^ƒRƒƒiƒEƒCƒ‹ƒXŠ´õÇ󋵉º‚É‚¨‚¯‚é‘åŠw¶‚ÌŽåŠÏ“IƒXƒgƒŒƒX en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SumiokaKyoko en-aut-sei=Sumioka en-aut-mei=Kyoko kn-aut-name=Z‰ª‹±Žq kn-aut-sei=Z‰ª kn-aut-mei=‹±Žq aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=˜aò—¢‰À kn-aut-sei=˜aò kn-aut-mei=—¢‰À aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwŠwpŒ¤‹†‰@ŽÐ‰ï•¶‰»‰ÈŠwŠwˆæ affil-num=2 en-affil= kn-affil=IGLˆã—ÕŸŽƒê–åŠwZŽ•‰È‰q¶Šw‰È END start-ver=1.4 cd-journal=joma no-vol=2021 cd-vols= no-issue= article-no= start-page=1 end-page=11 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=2021929 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Investigation of the molecular causes underlying physical abnormalities in Diamond]Blackfan anemia patients with RPL5 haploinsufficiency en-subtitle= kn-subtitle= en-abstract= kn-abstract=Diamond-Blackfan anemia (DBA) is a genetic disorder caused by mutations in genes encoding ribosomal proteins and characterized by erythroid aplasia and various physical abnormalities. Although accumulating evidence suggests that defective ribosome biogenesis leads to p53-mediated apoptosis in erythroid progenitor cells, little is known regarding the underlying causes of the physical abnormalities. In this study, we established induced pluripotent stem cells from a DBA patient with RPL5 haploinsufficiency. These cells retained the ability to differentiate into osteoblasts and chondrocytes. However, RPL5 haploinsufficiency impaired the production of mucins and increased apoptosis in differentiated chondrocytes. Increased expression of the pro-apoptotic genes BAX and CASP9 further indicated that RPL5 haploinsufficiency triggered p53-mediated apoptosis in chondrocytes. MDM2, the primary negative regulator of p53, plays a crucial role in erythroid aplasia in DBA patient. We found the phosphorylation level of MDM2 was significantly decreased in RPL5 haploinsufficient chondrocytes. In stark contrast, we found no evidence that RPL5 haploinsufficiency impaired osteogenesis. Collectively, our data support a model in which RPL5 haploinsufficiency specifically induces p53-mediated apoptosis in chondrocytes through MDM2 inhibition, which leads to physical abnormalities in DBA patients. en-copyright= kn-copyright= en-aut-name=FukuiYuko en-aut-sei=Fukui en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HayanoSatoru en-aut-sei=Hayano en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawanabeNoriaki en-aut-sei=Kawanabe en-aut-mei=Noriaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WangZiyi en-aut-sei=Wang en-aut-mei=Ziyi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShimadaAkira en-aut-sei=Shimada en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SaitoMegumu K. en-aut-sei=Saito en-aut-mei=Megumu K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AsakaIsao en-aut-sei=Asaka en-aut-mei=Isao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KamiokaHiroshi en-aut-sei=Kamioka en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=2 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=3 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=4 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= affil-num=5 en-affil=Department of Pediatric Hematology/Oncology Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Clinical Application, Center for iPS Cell Research and Application Kyoto University kn-affil= affil-num=7 en-affil=Department of Fundamental Cell Technology, Center for iPS Cell Research and Application Kyoto University kn-affil= affil-num=8 en-affil=Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University kn-affil= en-keyword=iPS cell kn-keyword=iPS cell en-keyword=RPL5 kn-keyword=RPL5 en-keyword=cleft lip and palate kn-keyword=cleft lip and palate en-keyword=chondrocyte kn-keyword=chondrocyte en-keyword=Diamond-Blackfan Anemia kn-keyword=Diamond-Blackfan Anemia END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=8 article-no= start-page=1876 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210409 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Assessment of Demineralization Inhibition Effects of Dentin Desensitizers Using Swept-Source Optical Coherence Tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=The purpose of this study was to evaluate the mechanism of action and the inhibiting effects of two types of desensitizers against dentin demineralization using pre-demineralized hypersensitivity tooth model in vitro. In this study, we confirmed that a hypersensitivity tooth model from our preliminary experiment could be prepared by immersing dentin discs in an acetic acid-based solution with pH 5.0 for three days. Dentin discs with three days of demineralization were prepared and applied by one of the desensitizers containing calcium fluoro-alumino-silicate glass (Nanoseal, NS) or fluoro-zinc-silicate glass (Caredyne Shield, CS), followed by an additional three days of demineralization. Dentin discs for three days of demineralization (de3) and six days of demineralization (de6) without the desensitizers were also prepared. The dentin discs after the experimental protocol were scanned using swept-source optical coherence tomography (SS-OCT) to image the cross-sectional (2D) view of the samples and evaluate the SS-OCT signal. The signal intensity profiles of SS-OCT from the region of interest of 300, 500, and 700 mu m in depth were obtained to calculate the integrated signal intensity and signal attenuation coefficient. The morphological differences and remaining chemical elements of the dentin discs were also analyzed using scanning electron microscopy and energy-dispersive X-ray spectroscopy. SS-OCT images of CS and NS groups showed no obvious differences between the groups. However, SS-OCT signal profiles for both the CS and NS groups showed smaller attenuation coefficients and larger integrated signal intensities than those of the de6 group. Reactional deposits of the desensitizers even after the additional three days of demineralization were observed on the dentin surface in NS group, whereas remnants containing Zn were detected within the dentinal tubules in CS group. Consequently, both CS and NS groups showed inhibition effects against the additional three days of demineralization in this study. Our findings demonstrate that SS-OCT signal analysis can be used to monitor the dentin demineralization and inhibition effects of desensitizers against dentin demineralization in vitro. en-copyright= kn-copyright= en-aut-name=MatsuzakiKumiko en-aut-sei=Matsuzaki en-aut-mei=Kumiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ShinnoYasuo en-aut-sei=Shinno en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OnoSerina en-aut-sei=Ono en-aut-mei=Serina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamajiKozo en-aut-sei=Yamaji en-aut-mei=Kozo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OharaNaoko en-aut-sei=Ohara en-aut-mei=Naoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Biomimetics Biomaterials Biophotonics Biomechanics & Technology Laboratory, Department of Restorative Dentistry, University of Washington kn-affil= affil-num=8 en-affil=Center of Advanced Medicine for Dental and Oral Diseases, Department for Advanced Dental Research, National Center for Geriatrics and Ger Ontology kn-affil= affil-num=9 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=10 en-affil=Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=dentin desensitizer kn-keyword=dentin desensitizer en-keyword=dentin demineralization kn-keyword=dentin demineralization END start-ver=1.4 cd-journal=joma no-vol=56 cd-vols= no-issue=1 article-no= start-page=109 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202011 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of dental caries, tooth crack, and age-related changes in tooth structure using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) is an imaging technique that can visualize the internal biological structure without X-ray exposure. Swept-source OCT (SS-OCT) is one of the latest version of OCT, wherein the light source is a tunable laser that sweeps near-infrared wavelength light to achieve real-time imaging. The imaging depth of OCT is highly influenced by the translucency of the medium. The medium that does not transmit light and the deeper structure beyond the range of light penetration depth are not relevant for OCT imaging. In OCT, sound enamel is almost transparent at the OCT wavelength range, and enamel and dentin can be distinguished from each other as the dentin-enamel junction (DEJ) appears as a dark border. Demineralized enamel and dentin are imaged as bright zones because of the formation of numerous micro-porosities where the backscatter of OCT signal is increased. In cavitated caries at interproximal or occlusal hidden zone, the upper margin of the cavity reflects the signal showing a distinct bright border in the SS-OCT image. SS-OCT is capable of determining crack penetration depth even when the cracks extended beyond the DEJ. SS-OCT has a high degree of sensitivity and specificity for the detection of dental caries and tooth cracks. SS-OCT is also capable of detecting non-carious cervical lesions and occlusal tooth wear in cross-sectional views to estimate the amount of tooth structure loss. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= en-keyword=Optical coherence tomography kn-keyword=Optical coherence tomography en-keyword=Diagnosis kn-keyword=Diagnosis en-keyword=Caries kn-keyword=Caries en-keyword=Tooth crack kn-keyword=Tooth crack en-keyword=NCCL kn-keyword=NCCL en-keyword=Tooth wear kn-keyword=Tooth wear en-keyword=Age-related changes kn-keyword=Age-related changes END start-ver=1.4 cd-journal=joma no-vol=56 cd-vols= no-issue=1 article-no= start-page=109 end-page=118 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of dental caries, tooth crack, and age-related changes in tooth structure using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) is an imaging technique that can visualize the internal biological structure without X-ray exposure. Swept-source OCT (SS-OCT) is one of the latest version of OCT, wherein the light source is a tunable laser that sweeps near-infrared wavelength light to achieve real-time imaging. The imaging depth of OCT is highly influenced by the translucency of the medium. The medium that does not transmit light and the deeper structure beyond the range of light penetration depth are not relevant for OCT imaging. In OCT, sound enamel is almost transparent at the OCT wavelength range, and enamel and dentin can be distinguished from each other as the dentin?enamel junction (DEJ) appears as a dark border. Demineralized enamel and dentin are imaged as bright zones because of the formation of numerous micro-porosities where the backscatter of OCT signal is increased. In cavitated caries at interproximal or occlusal hidden zone, the upper margin of the cavity reflects the signal showing a distinct bright border in the SS-OCT image. SS-OCT is capable of determining crack penetration depth even when the cracks extended beyond the DEJ. SS-OCT has a high degree of sensitivity and specificity for the detection of dental caries and tooth cracks. SS-OCT is also capable of detecting non-carious cervical lesions and occlusal tooth wear in cross-sectional views to estimate the amount of tooth structure loss. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= en-keyword=Optical coherence tomography kn-keyword=Optical coherence tomography en-keyword=Diagnosis kn-keyword=Diagnosis en-keyword=Caries kn-keyword=Caries en-keyword=Tooth crack kn-keyword=Tooth crack en-keyword=NCCL kn-keyword=NCCL en-keyword=Tooth wear kn-keyword=Tooth wear en-keyword=Age-related changes kn-keyword=Age-related changes END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue=21 article-no= start-page=6016 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Diagnosis of Occlusal Tooth Wear Using 3D Imaging of Optical Coherence Tomography Ex Vivo en-subtitle= kn-subtitle= en-abstract= kn-abstract=The aim of this study was to assess the utility of 3D imaging of optical coherence tomography (OCT) for the diagnosis of occlusal tooth wear ex vivo. Sixty-three extracted human molars with or without visible tooth wear were collected to take digital intraoral radiography and 3D OCT images. The degree of tooth wear was evaluated by 12 examiners and scored using 4-rank scale: 1-slight enamel wear; 2-distinct enamel wear; 3-tooth wear with slight dentin exposure; 4-tooth wear with distinct involvement of dentin. The degree of tooth wear was validated by the histological view of confocal laser scanning microscopy (CLSM). The sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic analysis were calculated. Diagnostic accuracy was compared with the agreement with CLSM observation using weighted kappa. The results were statistically analyzed at a significance level of alpha = 0.05. Three-dimensional OCT showed significantly higher sensitivity (p < 0.05) for all the diagnostic thresholds of enamel wear and dentin exposure than digital radiography (0.82, 0.85, and 0.79 vs. 0.56, 0.52, and 0.57, respectively). Three-dimensional OCT showed higher AUC and kappa coefficients than digital radiography (p < 0.05), where mean AUC and Kappa values were 0.95 and 0.76 for OCT and 0.92 and 0.47 for radiography, respectively. No significant difference of specificity was observed (p > 0.05). Three-dimensional OCT could visualize and estimate the degree of tooth wear and detect the dentin exposure at the tooth wear surface accurately and reproducibly. Consequently, a new guideline for tooth wear assessment can be proposed using OCT. en-copyright= kn-copyright= en-aut-name=KashiwaMisa en-aut-sei=Kashiwa en-aut-mei=Misa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Center of Advanced Medicine for Dental and Oral Diseases, Department for Advanced Dental Research, National Center for Geriatrics and Gerontology kn-affil= affil-num=6 en-affil=Department of Cariology and Operative Dentistry Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=occlusal tooth wear kn-keyword=occlusal tooth wear en-keyword=erosive tooth wear kn-keyword=erosive tooth wear en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=3D imaging kn-keyword=3D imaging en-keyword=enamel thickness kn-keyword=enamel thickness en-keyword=dentin exposure kn-keyword=dentin exposure en-keyword=demineralization kn-keyword=demineralization END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=1 article-no= start-page=15754 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=3D imaging of proximal caries in posterior teeth using optical coherence tomography en-subtitle= kn-subtitle= en-abstract= kn-abstract=Optical coherence tomography (OCT) can create cross-sectional images of tooth without X-ray exposure. This study aimed to investigate the diagnostic accuracy of 3D imaging of OCT for proximal caries in posterior teeth. Thirty-six human molar teeth with 51 proximal surfaces visibly 6 intact, 16 slightly demineralized, and 29 distinct carious changes were mounted to take digital radiographs and 3D OCT images. The sensitivity, specificity and area under the receiver operating characteristic curve (AUC) for the diagnosis of enamel caries and dentin caries were calculated to quantify the diagnostic ability of 3D OCT in comparison with digital radiography. Diagnostic accuracy was evaluated by the agreement with histology using weighted Kappa. OCT showed significantly higher sensitivity, AUC and Kappa values than radiography. OCT can be a safer option for the diagnosis of proximal caries in posterior teeth that can be applied to the patients without X-ray exposure. en-copyright= kn-copyright= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=BurrowMichael F. en-aut-sei=Burrow en-aut-mei=Michael F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ArakiKazuyuki en-aut-sei=Araki en-aut-mei=Kazuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ZhouYuan en-aut-sei=Zhou en-aut-mei=Yuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HosakaKeiichi en-aut-sei=Hosaka en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MiyazakiTakashi en-aut-sei=Miyazaki en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital kn-affil= affil-num=3 en-affil=Department of Oral Diagnostic Sciences, Division of Radiology, Showa University School of Dentistry kn-affil= affil-num=4 en-affil=Department of Preventive Dentistry, Shanghai Ninth Peoplefs Hospital, Shanghai Jiao Tong University School of Medicine kn-affil= affil-num=5 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences kn-affil= affil-num=6 en-affil=Department of Restorative Dentistry, University of Washington School of Dentistry kn-affil= affil-num=7 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=8 en-affil=Department of Conservative Dentistry, Division of Biomaterials and Engineering, Showa University School of Dentistry kn-affil= affil-num=9 en-affil=Department for Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology kn-affil= affil-num=10 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=Dental caries kn-keyword=Dental caries en-keyword=Dental lasers kn-keyword=Dental lasers en-keyword=Laboratory techniques and procedures kn-keyword=Laboratory techniques and procedures END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue=6 article-no= start-page=1659 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200317 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Diagnosis of Occlusal Caries with Dynamic Slicing of 3D Optical Coherence Tomography Images en-subtitle= kn-subtitle= en-abstract= kn-abstract=Detecting the extent of occlusal caries is a clinically important but challenging task required for treatment decision making. The aim of this study was to assess the diagnostic power of 3D swept-source optical coherence tomography (OCT) for evaluation of occlusal caries in comparison with X-ray radiography. Extracted human molars not exhibiting American Dental Association (ADA) criteria advanced caries were mounted in a silicone block and digital dental radiographs were captured from the buccal side. Subsequently, occlusal surfaces were scanned with a prototype Yoshida Dental OCT. Thirteen examiners evaluated the presence and extent of caries on radiographs and dynamically sliced 3D OCT video images, using a 4 level scale-0: intact; 1: enamel demineralization without cavitation; 2: enamel caries with cavitation; 3: dentin caries with or without cavitation. Sensitivity, specificity and area under operating characteristic curves (Az) were statistically analyzed (alpha = 0.05). Reliability analysis showed an excellent agreement among the 13 examiners for both methods. The OCT presented a significantly higher sensitivity and Az value for the detection of caries compared to radiographs (p < 0.05). Radiography showed especially low sensitivity for dentin caries (0-2 versus 3). Dynamic slicing of 3D OCT volumes is a powerful adjunct tool to visual inspection to diagnose the dentin occlusal caries in vitro. en-copyright= kn-copyright= en-aut-name=LuongMinh N. en-aut-sei=Luong en-aut-mei=Minh N. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ArakiKazuyuki en-aut-sei=Araki en-aut-mei=Kazuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Restorative Dentistry, University of Washington kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Division of Radiology, Department of Oral Diagnostic Sciences, Showa University School of Dentistry kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=6 en-affil=Department of Restorative Dentistry, University of Washington kn-affil= en-keyword=dentin kn-keyword=dentin en-keyword=enamel kn-keyword=enamel en-keyword=optical coherence tomography kn-keyword=optical coherence tomography en-keyword=radiograph kn-keyword=radiograph en-keyword=receiver operating characteristic (ROC) analysis kn-keyword=receiver operating characteristic (ROC) analysis en-keyword=hidden caries kn-keyword=hidden caries en-keyword=dentino-enamel junction DEJ kn-keyword=dentino-enamel junction DEJ END start-ver=1.4 cd-journal=joma no-vol=38 cd-vols= no-issue=385 article-no= start-page=798 end-page=805 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Effect of Flowable Composite Lining and Dentin Location on Microtensile Bond Strength and Internal Fracture Formation en-subtitle= kn-subtitle= en-abstract= kn-abstract=The objective of this study was to determine the effect of flowable composite lining and dentin location on internal dentin fracture formation in the microtensile bond strength (MTBS) test using swept-source optical coherence tomography (SS-OCT). MTBS test beams (1.0~1.0 mm) were prepared from human superficial and deep dentin, which was bonded with a self-etch adhesive (Clearfil SE Bond) and hybrid composite resin (Clearfil AP-X), with or without flowable lining (Clearfil Majesty ES-Flow). We tested 4 groups according to placement technique (with vs. without flowable liner) and dentin (superficial vs. deep) locations. Cross-sectional 2D images of the bonded interface were obtained before and after the MTBS test. Internal dentin fracture after MTBT was observed as a bright zone in SS-OCT. Flowable lining significantly reduced internal fracture formation in dentin (p<0.05). Dentin location significantly influenced MTBS (p<0.05), and this was reduced by flowable lining usage. en-copyright= kn-copyright= en-aut-name=KominamiNao en-aut-sei=Kominami en-aut-mei=Nao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HosakaKeiichi en-aut-sei=Hosaka en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=Minh Nguyet Luong en-aut-sei=Minh Nguyet Luong en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University. kn-affil= affil-num=3 en-affil=Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Restorative Dentistry and Endodontics, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City kn-affil= affil-num=5 en-affil=Department of Operative Dentistry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University. kn-affil= affil-num=6 en-affil=Biomimetics Biomaterials Biophotonics & Technology Laboratory, Department of Restorative Dentistry, University of Washington School of Dentistry kn-affil= affil-num=7 en-affil=National Center for Geriatrics and Gerontology, Department of Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Disease kn-affil= affil-num=8 en-affil= kn-affil= en-keyword=Dentin kn-keyword=Dentin en-keyword=Internal fracture kn-keyword=Internal fracture en-keyword=Microtensile bond strength test kn-keyword=Microtensile bond strength test en-keyword= SS-OCT kn-keyword= SS-OCT END start-ver=1.4 cd-journal=joma no-vol=38 cd-vols= no-issue=5 article-no= start-page=779 end-page=789 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cavity Adaptation of Composite Restorations Prepared at Crown and Root: Optical Assessment Using SS-OCT en-subtitle= kn-subtitle= en-abstract= kn-abstract= Evaluation of gap formation at the interfaces of a two-step self-etching adhesive with/without pre-etching was performed using sweptsource optical coherence tomography (SS-OCT). Round cavities were prepared in bovine incisors at the middle (MC) and cervical (CC) thirds of the crown and the cervical third of the root (CR). Clearfil SE bond was directly applied to one group (SE) and another (PA) was pretreated with K-etchant gel. Following restoration by flowable composite resin, the teeth were thermally challenged and stored for 2 months. Interfacial gaps observed in the cross-sectional OCT images were analyzed and the bottom cavities exhibited increased gaps compared to the margin and dentin-enamel junction (DEJ). The CR site had a larger gap than at MC and CC in the SE group. DEJ separation at the MC was significantly smaller than that at CC in both groups. Therefore, gap formation depends on the cavity region, location, and bonding protocol. en-copyright= kn-copyright= en-aut-name=Rima Zakzuk Alshahni en-aut-sei=Rima Zakzuk Alshahni en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaYasushi en-aut-sei=Shimada en-aut-mei=Yasushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ZhouYuan en-aut-sei=Zhou en-aut-mei=Yuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SadrAlireza en-aut-sei=Sadr en-aut-mei=Alireza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SumiYasunori en-aut-sei=Sumi en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TagamiJunji en-aut-sei=Tagami en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=2 en-affil=Department of Operative Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= affil-num=4 en-affil=Department of Operative Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Restorative Dentistry, University of Washington, School of Dentistry kn-affil= affil-num=6 en-affil=Division of Oral and Dental Surgery, Department of Advanced Medicine, National Center for Geriatrics and Gerontology, National Hospital for Geriatric Medicine kn-affil= affil-num=7 en-affil=Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=Bottom kn-keyword=Bottom en-keyword=Dentin-enamel junction kn-keyword=Dentin-enamel junction en-keyword=Gap kn-keyword=Gap en-keyword=SS-OCT kn-keyword=SS-OCT en-keyword=Self-etch adhesive kn-keyword=Self-etch adhesive END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰ÈŠÖ˜As“®‚ÆIgGR‘̉¿‚ÅŽ¦‚·Ž•Žü•aŒ´×‹Û‚ÌŠ´õ“x‚Æ‚ÌŠÖ˜A‚̉¡’fŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TsuboiAyaka en-aut-sei=Tsuboi en-aut-mei=Ayaka kn-aut-name=’؈䈻 kn-aut-sei=’؈ä kn-aut-mei=ˆ» aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ˆã—ÖÊÚ‚É‚¨‚¯‚éƒRƒ~ƒ…ƒjƒP[ƒVƒ‡ƒ“‚¨‚æ‚ÑŒ¤CŽ•‰Èˆã‚Ì‹¤Š´«‚Æ–Í‹[Š³ŽÒ•]‰¿‚Æ‚ÌŠÖŒW kn-title=Relationship of trainee dentistsf self-reported empathy and communication behaviors with simulated patientsf assessment in medical interviews en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeSho en-aut-sei=Watanabe en-aut-mei=Sho kn-aut-name=“nç³ãÄ kn-aut-sei=“nç³ kn-aut-mei=ãÄ aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=2 article-no= start-page=76 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120820 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Perioperative Management Training Program on the Awareness of Team Medicine among Trainee Dentists kn-title=Ž•‰ÈˆãŽt—Õ°Œ¤C‚É‚¨‚¯‚éƒ`[ƒ€ˆã—ÃŒ¤CƒvƒƒOƒ‰ƒ€ : Œ¤CŽ•‰Èˆã‚ÌŠÖS‚¨‚æ‚Ñ—‰ð‚É—^‚¦‚½Œø‰Ê‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= 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en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=X“cŠw kn-aut-sei=X“c kn-aut-mei=Šw aut-affil-num=8 ORCID= affil-num=1 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=2 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=3 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=4 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@‘‡Ž•‰È affil-num=5 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@‘‡Ž•‰È affil-num=6 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@‘‡Ž•‰È affil-num=7 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@‘‡Ž•‰È affil-num=8 en-affil=Hospital Dentistry, Okayama University Hospital kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” en-keyword=Œ¤CŽ•‰Èˆã kn-keyword=Œ¤CŽ•‰Èˆã en-keyword=Ž•‰ÈˆãŽt—Õ°Œ¤C kn-keyword=Ž•‰ÈˆãŽt—Õ°Œ¤C en-keyword=ƒ`[ƒ€ˆã—à kn-keyword=ƒ`[ƒ€ˆã—à en-keyword=ŽüpŠúŠÇ— kn-keyword=ŽüpŠúŠÇ— END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‘OŽ••”ŠJ™ùŠ³ŽÒ‚ɑ΂µ‚Äs‚í‚ê‚Ä‚¢‚鎕‰È‹¸³—pƒAƒ“ƒJ[ƒXƒNƒŠƒ…[‚ð—p‚¢‚½Ž¡—ÂƊO‰È“I‹¸³Ž¡—Â̊{‰^“®C™ðš‰^“®‚Ì‹@”\•]‰¿ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=FujisawaAtsuro en-aut-sei=Fujisawa en-aut-mei=Atsuro kn-aut-name=“¡àVŒú˜Y kn-aut-sei=“¡àV kn-aut-mei=Œú˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ž•‰È•ÛŒ’‚Ì’mŽ¯‚¨‚æ‚Ñ‚»‚Ìî•ñŒ¹‚ÆŽ•‰È•ÛŒ’s“®‚Æ‚ÌŠÖ˜A‚ɂ‚¢‚Ẳ¡’fŒ¤‹† kn-title=Associations between dental knowledge, source of dental knowledge and oral health behavior in Japanese university students: A cross-sectional study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TaniguchiAyano en-aut-sei=Taniguchi en-aut-mei=Ayano kn-aut-name=’JŒûˆ»”T kn-aut-sei=’JŒû kn-aut-mei=ˆ»”T aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Control of contamination in dental unit water lines applying low-concentrated ozonized water : Effectiveness and Safety kn-title=’á”Z“xƒIƒ]ƒ“…‚ð‰ž—p‚µ‚½Ž•‰È—pƒ†ƒjƒbƒg‹‹…ŠÇ˜H“à‰˜õ‚̧Œä : —LŒø«‚ƈÀ‘S«‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OkuboKeisuke en-aut-sei=Okubo en-aut-mei=Keisuke kn-aut-name=‘å‹v•ÛŒ\—S kn-aut-sei=‘å‹v•Û kn-aut-mei=Œ\—S aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠwˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‹}«Šú”]‘²’†Š³ŽÒ‚ɑ΂·‚鎕‰È‰î“ü‚É‚æ‚éŒûoŠ´õ‚ÆŒoŒû‰h—{ÛŽæ‚ÌŠÇ—Œø‰Ê‚ÉŠÖ‚·‚éŒãŒü‚«Œ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsunagaKazuyuki en-aut-sei=Matsunaga en-aut-mei=Kazuyuki kn-aut-name=¼‰iˆêK kn-aut-sei=¼‰i kn-aut-mei=ˆêK aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=‰ªŽR‘åŠw‘åŠwˆãŽ•–òŠw‘‡Œ¤‹†‰È END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=3 article-no= start-page=191 end-page=196 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Our experience with the significance of collaborative medical and dental surgeries at the Head and Neck Cancer Center, Okayama University Hospital kn-title=‰ªŽR‘åŠw•a‰@“ªèò•”‚ª‚ñƒZƒ“ƒ^[‚É‚¨‚¯‚éˆã‰ÈŽ•‰È‡“¯Žèp‚ÌŒ»ó‰ðÍ‚Æ‚»‚̈Ӌ` en-subtitle= kn-subtitle= en-abstract= kn-abstract=@@We have been collaborating with head and neck surgeons, plastic surgeons and oral surgeons in surgeries for many patients with head and neck carcinomasi especially oral carcinomasj since 2006i fiscal year 2005j. The Head and Neck Cancer Center was established at Okayama University Hospital in 2012. @This Center was the first of its kind at a national university hospital in Japan. @At the Center, 174 operations on head and neck carcinomas and 96 reconstructive operations were performed in 2014i fiscal yearj. @Medical and dental collaborative operations have been increasing almost every year since the 2005 fiscal year. There were 45 collaborative operations in the 2014 fiscal year, which included 30 cases of bone or metal plate reconstruction or plate reinforcement of the jaws. @There were 76 medical and dental collaborative operations in the 7 years before the establishment of the Center, with a mean of 10.9 operations per year. Since the establishment of the Center, there have been 112 cases over 3 years with a mean of 37.3 operations per year. 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kn-title=ˆã—ÂÌ"‚¢‚Ü"‚ð“`‚¦‚é@ŽüpŠú‚É‚¨‚¯‚éˆã‰È-Ž•‰È˜AŒg@•a‰@ˆã—Âւ̎•‰È‰q¶Žm‚ÌŽQ‰æ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ ŽüpŠúŠÇ—ƒZƒ“ƒ^[Ž•‰È•”–å END start-ver=1.4 cd-journal=joma no-vol=32 cd-vols= no-issue=2 article-no= start-page=57 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=201312 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Survey of first dental examination system for patients referred from medicine to dentistry in Okayama University Hospital \FY2010 and 2011 report\ kn-title=‰ªŽR‘åŠw•a‰@Ž•‰ÈŒnf—Éȓ™‚ªˆã‰ÈŒnf—Éȓ™‚©‚çŽó‚¯‚½‰@“àЉî‚Æ‚»‚ê‚ɑ΂·‚鉓®‘Ήž@\•½¬22”N“x‚Æ23”N“x‚ð‘ÎÛ‚Æ‚µ‚½ŽÀ‘Ô’²¸\ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko 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kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‹¸³Ž•‰ÈŽ¡—ʳŽÒ‚ÌŒûoŠÖ˜AQuality of Life‚Ì•]‰¿ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KomoriHiroki en-aut-sei=Komori en-aut-mei=Hiroki kn-aut-name=ŒÃXhŠî kn-aut-sei=ŒÃX kn-aut-mei=hŠî aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Œ»ÝŽ•”‚Æ‘Ìd‘‰ÁE”ì–ž‚Ì”­¶‚ÌŠÖ˜A?Šé‹ÆŽ•‰ÈŒŸfŽófŽÒ‚ð‘ÎÛ‚Æ‚µ‚½‘OŒü‚«ƒRƒz[ƒgŒ¤‹†- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakiuchiHiroya en-aut-sei=Takiuchi en-aut-mei=Hiroya kn-aut-name=‘ë“à”Ž–ç kn-aut-sei=‘ë“à kn-aut-mei=”Ž–ç aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=2 end-page=3 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100901 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ˆÚAŒã‡•¹Ç‚ÌŠÅŒìƒ|ƒCƒ“ƒg„ŸGVHD‡B ŒûoGVHD en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=™‰Y—TŽq kn-aut-sei=™‰Y kn-aut-mei=—TŽq aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘O“c‰ÃM kn-aut-sei=‘O“c kn-aut-mei=‰ÃM aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ ˆã—ËZp•”iŽ•‰È•”–åj Ž•‰È‰q¶ŽmŽº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ Ž•Žü‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ ŒŒ‰tEŽîᇓà‰È END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=1 article-no= start-page=37 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=200906 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Achievements and Next Themes of Dental Section of Perioperative Management Center in Okayama University Hospital at 5 Months after Establishment kn-title=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å)Ý—§Œã5ƒ•ŒŽŠÔ‚ÌŠˆ“®“à—e‚¨‚æ‚Ñ¡Œã‚Ì“WŠJ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name=ŽR’†—æŽq kn-aut-sei=ŽR’† kn-aut-mei=—æŽq aut-affil-num=1 ORCID= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=2 ORCID= en-aut-name=NawachiKumiko en-aut-sei=Nawachi en-aut-mei=Kumiko kn-aut-name=“ê’t‹v”üŽq kn-aut-sei=“ê’t kn-aut-mei=‹v”üŽq aut-affil-num=3 ORCID= en-aut-name=YanagiYoshinobu en-aut-sei=Yanagi en-aut-mei=Yoshinobu kn-aut-name=–ö•¶C kn-aut-sei=–ö kn-aut-mei=•¶C aut-affil-num=4 ORCID= en-aut-name=KodamaNaoki en-aut-sei=Kodama en-aut-mei=Naoki kn-aut-name=™Z‹Ê’¼‹I kn-aut-sei=™Z‹Ê kn-aut-mei=’¼‹I aut-affil-num=5 ORCID= en-aut-name=NakataTakashi en-aut-sei=Nakata en-aut-mei=Takashi kn-aut-name=’†“c‹M kn-aut-sei=’†“c kn-aut-mei=‹M aut-affil-num=6 ORCID= en-aut-name=MiuraRumi en-aut-sei=Miura en-aut-mei=Rumi kn-aut-name=ŽO‰Y—¯”ü kn-aut-sei=ŽO‰Y kn-aut-mei=—¯”ü aut-affil-num=7 ORCID= en-aut-name=HagawaMisao en-aut-sei=Hagawa en-aut-mei=Misao kn-aut-name=‰Hì‘€ kn-aut-sei=‰Hì kn-aut-mei=‘€ aut-affil-num=8 ORCID= en-aut-name=TakeuchiTetsuo en-aut-sei=Takeuchi en-aut-mei=Tetsuo kn-aut-name=’|“à“N’j kn-aut-sei=’|“à kn-aut-mei=“N’j aut-affil-num=9 ORCID= en-aut-name=YamaneMieko en-aut-sei=Yamane en-aut-mei=Mieko kn-aut-name=ŽRª”üžÄŽq kn-aut-sei=ŽRª kn-aut-mei=”üžÄŽq aut-affil-num=10 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=X“cŠw kn-aut-sei=X“c kn-aut-mei=Šw aut-affil-num=11 ORCID= en-aut-name=TakashibaShogo en-aut-sei=Takashiba en-aut-mei=Shogo kn-aut-name=‚ŽÄ³Œå kn-aut-sei=‚ŽÄ kn-aut-mei=³Œå aut-affil-num=12 ORCID= en-aut-name=AsamiJun-ichi en-aut-sei=Asami en-aut-mei=Jun-ichi kn-aut-name=óŠC~ˆê kn-aut-sei=óŠC kn-aut-mei=~ˆê aut-affil-num=13 ORCID= en-aut-name=MinagiShogo en-aut-sei=Minagi en-aut-mei=Shogo kn-aut-name=ŠF–ØÈŒá kn-aut-sei=ŠF–Ø kn-aut-mei=ÈŒá aut-affil-num=14 ORCID= en-aut-name=YoshiyamaMasahiro en-aut-sei=Yoshiyama en-aut-mei=Masahiro kn-aut-name=‹gŽR¹G kn-aut-sei=‹gŽR kn-aut-mei=¹G aut-affil-num=15 ORCID= en-aut-name=ShimonoTsutomu en-aut-sei=Shimono en-aut-mei=Tsutomu kn-aut-name=‰º–ì•× kn-aut-sei=‰º–ì kn-aut-mei=•× aut-affil-num=16 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name=ŒE–Ø‘ñ’j kn-aut-sei=ŒE–Ø kn-aut-mei=‘ñ’j aut-affil-num=17 ORCID= en-aut-name=SasakiAkira en-aut-sei=Sasaki en-aut-mei=Akira kn-aut-name=²X–ؘN kn-aut-sei=²X–Ø kn-aut-mei=˜N aut-affil-num=18 ORCID= en-aut-name=MoritaKiyoshi en-aut-sei=Morita en-aut-mei=Kiyoshi kn-aut-name=X“cŒ‰ kn-aut-sei=X“c kn-aut-mei=Œ‰ aut-affil-num=19 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ËZp•”Ž•‰È‰q¶ŽmŽº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ËZp•”Ž•‰È‹ZHŽº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŽüpŠúŠÇ—ƒZƒ“ƒ^[(Ž•‰È•”–å) affil-num=11 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È—\–hŽ•‰ÈŠw•ª–ì affil-num=12 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰ÈŽ•Žü•a‘ÔŠw•ª–ì affil-num=13 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰ÈŽ•‰È•úŽËüŠw•ª–ì affil-num=14 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È™ù‡E—L°‹`Ž••â’ÔŠw•ª–ì affil-num=15 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰ÈŽ•‰È•Û‘¶C•œŠw•ª–ì affil-num=16 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ËZp•”Ž•‰È‰q¶ŽmŽº affil-num=17 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰ÈƒCƒ“ƒvƒ‰ƒ“ƒgĶ•â’ÔŠw•ª–ì affil-num=18 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@•›•a‰@’· affil-num=19 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@•a‰@’· END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=­—ʂ̃~ƒ_ƒ]ƒ‰ƒ€“Š—^‚É‚æ‚é‚ŒŒˆ³Ž•‰ÈŠ³ŽÒ‚ÌŒŒˆ³ˆÀ’艻Œø‰Ê?“ñd–ÓŒŸƒ‰ƒ“ƒ_ƒ€‰»”äŠrŽŽŒ±? en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeYoshihisa en-aut-sei=Watanabe en-aut-mei=Yoshihisa kn-aut-name=“n•Ó’õ‹v kn-aut-sei=“n•Ó kn-aut-mei=’õ‹v aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=2 article-no= start-page=67 end-page=71 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=201212 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Survey of first dental examination systern for patients referred frorn medicine to dentistry in Okayarna University Hospital-2010 report kn-title=‰ªŽR‘åŠw•a‰@Ž•‰ÈŒnf—Éȓ™‚ªˆã‰ÈŒnf—Éȓ™‚©‚çŽó‚¯‚½‰@“àЉî‚Æ‚»‚ê‚ɑ΂·‚鉓®‘Ήž \ •½¬22”N“x‚ð‘ÎÛ‚Æ‚µ‚½ŽÀ‘Ô’²¸\ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=1 ORCID= en-aut-name=KurashigeEmiko en-aut-sei=Kurashige en-aut-mei=Emiko kn-aut-name=‘ dŒb”üŽq kn-aut-sei=‘ d kn-aut-mei=Œb”üŽq aut-affil-num=2 ORCID= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name=ŽR’†—æŽq kn-aut-sei=ŽR’† kn-aut-mei=—æŽq aut-affil-num=3 ORCID= en-aut-name=YoshitomiAiko en-aut-sei=Yoshitomi en-aut-mei=Aiko kn-aut-name=‹g•yˆ¤Žq kn-aut-sei=‹g•y kn-aut-mei=ˆ¤Žq aut-affil-num=4 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=X“cŠw kn-aut-sei=X“c kn-aut-mei=Šw aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ˆã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=1 article-no= start-page=1 end-page=10 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=201112 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Necessity of Hospital Dentistry to Support Paticnts Undergoig Medical Treatment: Discussion based on a Case of Intensive lnterventions in Perioperative Management kn-title=•a‰@ˆã—ÃŽx‰‡‚ð–Ú“I‚Æ‚µ‚½Œûo‚ÌŠÇ—Šw‚¨‚æ‚Ñê–åf—Õª–ì‚Ì•K—v«\ŽüpŠúˆã—Âւ̎•‰È“I‰î“ü‚ð—á‚Æ‚µ‚Ä\ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name=‘]‰äŒ«•F kn-aut-sei=‘]‰ä kn-aut-mei=Œ«•F aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@’†‰›f—ÃŽ{݈ã—ÃŽx‰‡Ž•‰ÈŽ¡—Õ” en-keyword=hospital dentistry kn-keyword=hospital dentistry en-keyword=collaborative approaches kn-keyword=collaborative approaches en-keyword=perioperative management kn-keyword=perioperative management END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰Èˆ’u‚ªŽ©—¥_ŒoŒn‚É‹y‚Ú‚·‰e‹¿ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=UmetaniKensaku en-aut-sei=Umetani en-aut-mei=Kensaku kn-aut-name=”~’JŒ’ì kn-aut-sei=”~’J kn-aut-mei=Œ’ì aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=áŠQŽÒŽ•‰ÈŽófŠ³ŽÒ‚É‚¨‚¯‚霗ʂ̎À‘Ô‚¨‚æ‚Ñœ—Ê‚ÆŽ•‚Ì‘rŽ¸Œ´ˆö‚Æ‚ÌŠÖ˜A‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NumamotoYoko en-aut-sei=Numamoto en-aut-mei=Yoko kn-aut-name=À–{—fŽq kn-aut-sei=À–{ kn-aut-mei=—fŽq aut-affil-num=1 ORCID= 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kn-title=Surface-Based Registration‚ð—˜—p‚µ‚½ 3ŽŸŒ³CBCTimage‚Ìd‚ˇ‚킹‚Æ‚»‚̉ž—p—á(1) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‚–؉ël kn-aut-sei=‚–Ø kn-aut-mei=‰ël aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=“cˆä‹K”\ kn-aut-sei=“cˆä kn-aut-mei=‹K”\ aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=˜ÅâÄŽƒ kn-aut-sei=˜Åâ kn-aut-mei=ÄŽƒ aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=’JK–LŽõ kn-aut-sei=’JK kn-aut-mei=–LŽõ aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=¼ŽR–¾Œc kn-aut-sei=¼ŽR kn-aut-mei=–¾Œc aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=²“¡NŽç kn-aut-sei=²“¡ kn-aut-mei=NŽç aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=‚½‚¢‹¸³Ž•‰È affil-num=2 en-affil= kn-affil=‚½‚¢‹¸³Ž•‰È affil-num=3 en-affil= kn-affil=’·è‘åŠwˆãŽ•–ò‘‡Œ¤‹†‰È‹¸³Šw•ª–ì affil-num=4 en-affil= kn-affil=ƒƒfƒBƒbƒNƒGƒ“ƒWƒjƒAƒŠƒ“ƒO affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@ŒûoŠO‰Èi•a‘ÔŒnj affil-num=6 en-affil= kn-affil=‚½‚¢‹¸³Ž•‰È END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=1 article-no= start-page=355 end-page=359 dt-received= dt-revised= dt-accepted= dt-pub-year=1955 dt-pub=19550131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰Èˆã‚ð–K‚ê‚Ä”­Œ©‚³‚ꂽ’P‹…«”’ŒŒ•a‚̈êÇ—á en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‰¡Œ´Œ“‹v kn-aut-sei=‰¡Œ´ kn-aut-mei=Œ“‹v aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=•“cŸ”ü kn-aut-sei=•“c kn-aut-mei=Ÿ”ü aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”“à‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=9 article-no= start-page=2357 end-page=2389 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=CLINICAL AND EXPERIMENTAL STUDIES ON PERIODONTOSIS AND HISTAMINE kn-title=Ž•‘…”^˜RǂƃqƒXƒ^ƒ~ƒ“‚ÌŠÖŒW‚ÉŠÖ‚·‚é—Õ°“I•À‚ÉŽÀŒ±“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=These studies were made for the purpose of finding out the relationship of periodontosis to histamine and the etiologic factors of the disease since the pharmacological action of histamine is very similar to the inflammatory state of periodontosis. The results obtained are summarized as follows: 1) Gingivae of 51 cases of periodontosis showed a threefold increase in histamine, compared with those of 20 control cases operated surgically in the oral cavity. It is suggested by these results, in conjunction with the histopathological observations, that periodontosis has a certain relationship to allergy. 2) In cases of periodontosis an increase in mast cells and their morphologic changes were noticed in the microscopic specimens when stained with a one per cent solution of toluidine blue. These findings are known to be positively correlated with an increase of histamine. 3) In the animal experiments an increase of gingival histamine could not be attributed to physico-chemical stimulation alone and it was not noted when a local anaphylaxis (allergy) was induced. However, it became particularly marked when the local anaphylaxis was compounded by the above-mentioned strong stimulation. These animals showed both macroscopic and microscopic changes suggestive of periodontosis. 4) In slight or early cases of periodontosis favorable results were obtained by topical applications of sinomenine and an anti-histamine ointment which were administered in order to eliminate excessive amounts of histamine in the gingiva. Therefore it may be concluded that periodontosis has a close relationship to histamine and allergy. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=“¡‰ªK—Y kn-aut-sei=“¡‰ª kn-aut-mei=K—Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=4 article-no= start-page=1047 end-page=1052 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Sepsis due to Deciduous Caries kn-title=“ûŽ•êšI‚É‹Nˆö‚·‚é‘SgÇó‚ÉA‚¢‚Ä en-subtitle= kn-subtitle= en-abstract= kn-abstract=One hundred and sixteen children, aged 2 to 11 years, who visited Department of Oral Surgery. Okayama University Medical School from July, 1955 to June, 1956 and had more than one deciduous carious teeth of C(3) or higher grade, were investigated and summarized. Forty-three did not have any systemic symptom suspectedly due to deciduous caries, while 71 had some systemic symptoms. The latter group was analyzed accordting to their age and the seasons when they had visited. During the same period, nine cases complaining of unknown fever or some kind of systemic disturbance who visited Pediatric Department first were referred to our Department, suspecting the deciduous caries as their causes. These cases were diagnosed as nephritis, rheumatic fever or allergic sepsis in the Pediatric Department and they had many deciduous caries of C(3) or higher grade. Then it could be found that the systemic symptoms disappeared after these suspicious teeth had been treated. This fact may reveal that apical lesion was frequently seen following deciduous caries and gave sometimes an onset to the severe systemic diseases. en-copyright= kn-copyright= en-aut-name=AkitaKazuo en-aut-sei=Akita en-aut-mei=Kazuo kn-aut-name=H“c˜a•v kn-aut-sei=H“c kn-aut-mei=˜a•v aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=11-2 article-no= start-page=7855 end-page=7860 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Various Techniques for Treating Alveolar Pyorrhoea kn-title=]—ˆ‚Ì‚à‚Ì‹y‚ÑŽ„‹¤‚Ìs‚‚Ă¢‚鎕‘…”^˜Rǂɑ΂·‚鎡—Õûj‚Æ‚»‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= kn-abstract=In a previous report the anthors presented their suggestions for the surgical treatment of alveolar pyorrhoea. However, after further experience in a clinic established specifically for the treatment of this disease, new modes of treatment have been utilized and are reported upon in this paper. The authors discuss for removing the cause of the disease (systemic and local), symptomatic treatment (anti-inflammatory, repair of gingival pocket, and immobilization of loose teeth), supplementary and after-treatments; and they also reappraise the entire approach to the treatment of the disease. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=“¡‰ªK—Y kn-aut-sei=“¡‰ª kn-aut-mei=K—Y aut-affil-num=1 ORCID= en-aut-name=FukuiTetsuya en-aut-sei=Fukui en-aut-mei=Tetsuya kn-aut-name=•Ÿˆä“N–ç kn-aut-sei=•Ÿˆä kn-aut-mei=“N–ç aut-affil-num=2 ORCID= en-aut-name=SakuraiYasuro en-aut-sei=Sakurai en-aut-mei=Yasuro kn-aut-name=÷ˆä–õ˜Y kn-aut-sei=÷ˆä kn-aut-mei=–õ˜Y aut-affil-num=3 ORCID= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=¬—Ñ•qs kn-aut-sei=¬—Ñ kn-aut-mei=•qs aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=11-2 article-no= start-page=7849 end-page=7853 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Suggestions on Surgical Treatment of Alveolar Pyorrhoea kn-title=Ž•‘…”^˜RÇ‚ÌŠO‰È“I—Ö@‚È‚ç‚Ñ‚É‚»‚Ì“K‰ž‚ÉŠÖ‚·‚鎄Œ© en-subtitle= kn-subtitle= en-abstract= kn-abstract=The nature of pathological changes in alveolar pyorrhoea is so complicated and varied, that there are many methods of attack in the treatment of this disease. For the clinicians who actually handle such cases, it is essential to select the most suitable treatment, so that recovery may be swiftly brought about. With this point in mind, the authors present their suggestions on surgical treatment, including gingival curettage, gingivectomy, flap operation of the gingiva (as well as its modified method), and tooth extraction. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=“¡‰ªK—Y kn-aut-sei=“¡‰ª kn-aut-mei=K—Y aut-affil-num=1 ORCID= en-aut-name=FukuiTetsuya en-aut-sei=Fukui en-aut-mei=Tetsuya kn-aut-name=•Ÿˆä“N–ç kn-aut-sei=•Ÿˆä kn-aut-mei=“N–ç aut-affil-num=2 ORCID= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=¬—Ñ•qs kn-aut-sei=¬—Ñ kn-aut-mei=•qs aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6210 end-page=6221 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar III. Histo-Pathological Study kn-title=‰ºŠ{’qŽ•ŽüˆÍ‰Š‚ÉŠÖ‚·‚錤‹† ‘æ3•Ò ‰ºŠ{’qŽ•ŽüˆÍ‰Š‚Ì•a—‘gDŠw“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Biopsy was taken from the gingivae in 42 cases of pericoronitis and 8 normal healthy control cases, which were the same materials used in previous cytologic study. Sections were stained by Hematoxylin-Eosin, Azan and Papanicolaou methods, investigated histopathologically and compared with the findings of exfoliative cytology. 1) In normal gingivae keratinous layer could be seen in various degrees, while in acute inflammatory ones typical keratinous layer could not be observed and keratinization showed a decrease. 2) In Azan and Papanicolaou stainings yellow and red stainings decreased in the superficial layer and a definite correlation could be seen between keratinization and staining effect according to structural density of the tissue. Findings of exfoliative cytology and histo-pathology were completely agreed in their comaprison. 3) The SH groups of the surrounding tissue in case of pericoronitis were investigated by Ch?vremout-Er?d?ricq's reaction but a decisive conclusion could not be drawn from these results. It could be concluded that pericoronitis was induced by infection of the dental follicle after tooth eruption and could be divided into acute and chronic types clinically. As the results obtained from exfoliated epithelial cells classified according to their staining effect of the cytoplasm by Papanicolaou staining, a considerable decrease of keratinization could be noticed in cases of pericoronitis in comparison with normal controls. This fact could be proven by histo-pathological examination. Consequently clinical data, exfoliative cytogy and histo-pathology in case of pericoronitis coincided in their findings. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=¼ˆä?s kn-aut-sei=¼ˆä kn-aut-mei=?s aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6197 end-page=6209 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar II. Exfoliative Cytologic Study kn-title=‰ºŠ{’qŽ•ŽüˆÍ‰Š‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò ‰ºŠ{’qŽ•ŽüˆÍ‰Š‚Ì”—£×–EŠw“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Smear specimens were prepared from the inner surface of lower wisdom teeth of 20 normal healthy control cases and 252 cases of pericoronitis and stained by Papanicolaou and Giemsa. 1) Cytoplasm showed yellow, red mixed with blue or blue mixed with red, and blue according to the progress of keratinization by Papanicolaou staining. In chronic cases cells were more poorly stained than in normal control and acute cases. 2) Exfoliated epitheilail cells were classified accoding to keratinization or cytoplamic colors by staining and a definite relationship between progress of keratinization of acute and chronic cases could be statistically noticed as to rise and fall of the disease. The severer symptoms shows the inflammation. the lower tends the keratinization, and parabasal cells and atypical cells increased in their number as a specific finding. 3) Regressive changes were most remarkable in chronic cases, which were followed by acute and normal cases in the order. 4) The largest number of white blood cells could be seen in acute cases and as the disease proceeds to chronic type, they showed a decrease, which could be helpful to observation of the clinical progress. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=¼ˆä?s kn-aut-sei=¼ˆä kn-aut-mei=?s aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6187 end-page=6196 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Pericoronitis of the Lower Third Molar I. Clinico-Statistical Observation kn-title=‰ºŠ{’qŽ•ŽüˆÍ‰Š‚ÉŠÖ‚·‚錤‹† ‘æ1•Ò ‰ºŠ{’qŽ•ŽüˆÍ‰Š‚Ì—Õ°“Œv“IŠÏŽ@ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinico-Statistical findings were summarized in 252 cases of clinically diagnosed pericoronitis of the lower third molar. 1) Sex and Age Incidence: Generally speaking it could be seen a little more frequently in male, while more often in female before about 30 years of age, but a contrary tendency could be noticed with the progress of age. Eight per cent of all the cases were between the ages of 20 and 29 years. 2) Seasonal Incidence: It showed a decaease in the order of fall, spring, summer and winter. 3) Side Incidence: Almcst no difference of incidence could be seen between right and left sides. As for inclination of the eruption normal position was most frequent in acute cases, while mesial and horizontal inclincations more frequent in chronic cases. Twenty-eight per cent of all the cases showed the findings of bone resorption of the alveolar process. 4) Clinical Findings: They were almost agreed with those of previous description except lower incidence of disturbed mouth opening and fever which had been considered to be the most frequent symptoms so far. According to the clinical findings all the cases could be classified into acute and chronic ones at the ratio of 15 to 85. As a conclusion the fact that a cusp or a part of the crown had been exposed in all the cases examined may suggest that pericoronitis was due to infection of the dental follicle after eruption and had hardly connection with insufficiency of the space, direction of eruption, and difference of localiztion. en-copyright= kn-copyright= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=¼ˆä?s kn-aut-sei=¼ˆä kn-aut-mei=?s aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6145 end-page=6165 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Changes of Eosinophil Leucocytes in Alveolar Pyorrhea kn-title=Ž•‘…”^˜Rǂɉ—‚¯‚éDŽ_‹…‚ÌÁ’·‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hematological researches in peripheral blood, especially the changes of eosinophils were made from various points in order to solve the nature and etiology of alveolar pyorrhea. The results obtained are summarized as follows: 1) Little difference was recognized on red cell count, hemoglobin quantity and index in comparison with healthy control cases. No remarkable quantitative and qualitative changes of white cells except eosinophils were observed. In addition, any apparent difference between peripheral blood taken from the ear lobe and local gingiva could not be found in these above-mentioned points, 2) Increase of eosinophils was recognized in about 45 per cent of 78 cases, and, moreover, its remarkable relationship to clinical type, especially that of inflammatory findings characterstic of the disease, was suggested. Many cases showing morphological changes, especially degenerative changes of the cells, were observed, and, furthermore, relationlhip between changes of the cells and those of the disease conld be suggested as the experimental results 3) Peroxidizing reaction of the peripheral blood cells by the vitamin C method was investigated in 20 cases showing an increase of eosinophils. Consequently, quite difference could be observed in staining ability of granules between clinical cases and control cases, and thus it could be noticed that granules within the cells in case of alveolar pyorrhea were quantitatively different from those in normal ones. 4) As a result of vital observations on movement of eosinophils by the peripheral blood culture method in 10 cases of the disease, it was recognized that the migration velocity of the cells showed a rapid decrease as time went by and was markedly inferior to that of normal cases and that in the mobility form the cells suggestive findings of declining mobility increased much more than those of normal cases, especially showing a increasing tendency with the progress of culture. All of these various findings of the cells can not necessarily be considered to be the phenomena characteristic of this disease, but pathologic findings and characterics of the cells of this disease may suggest both correlation of the cells to chronic inflammatory changes in case of alveolar pyorrhea and possibility of allergic process as an etiologic factor of the disease. en-copyright= kn-copyright= en-aut-name=SakuraiYasuo en-aut-sei=Sakurai en-aut-mei=Yasuo kn-aut-name=÷ˆä–õ˜Y kn-aut-sei=÷ˆä kn-aut-mei=–õ˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6069 end-page=6088 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exfoliative Cytology of the Mouth Washings and Garglings kn-title=ôò•À‚Ñ‚ÉŠÜšu‚É‚æ‚éŒûo”—£×–E‚ÉŠÖ‚·‚錤‹† ‘æ2•Ò •a“IŒûo”—£×–EŠw en-subtitle= kn-subtitle= en-abstract= kn-abstract=Direct smear technic has been adopted in almost all the study on exfoliative cytology of the oral cavity, but cytology of the mouth washings and garglings has not been made so far. Therefore the author determined the most satisfactory centrifuging factors of the mouth washings and garglings to collect cells in the previous study. Now in this study cells were collected by means of centrifugation, membrane filter method and cell block method in normal healthy controls-25 newborns and sucklings, 30 adults. and 28 edentulous old persons with normal healthy oral cavity and in various clinical cases-24 malignancies, 6 benign tumors, 5 various other oral lesions, and 41 smokers. All the specimens were stained by Papanicolaou technic. I. NORMAL CYTOLOGY 1) Both nuclei and cytoplasms were larger in red and blue precornified epithelial cells, while somewhat smaller in orange keratinized cells showing pycnosis or disappearance of nuclei. 2) Fewer white blood cells were noticed in newborns, sucklings and old persons, while much more in the adults. These results may be due to the presence of gingival pockets, in other words the presence of teeth. 3) With the progress of age keratinized cells or those with keratinizing tendencies showed an increase, and those with regressive changes revealed the same findings. These results could be statistically proven significant and there was an aggreement between these cytologic and histologic findings. II. PATHOLOGIC CYTOLOGY Centrifugation 1) Most of the exfoliated malignant cells showed blue cytoplasm, which could be considered they were low-keratinized immature cells. 2) Of 21 cases confirmed of carcinoma by biopsy cytology-positive cases were 81 per cent in direct smear method and 52 per cent in centrifugation befor operation and 35 per cent in the former and 50 per cent in the latter after operation. 3) Sarcoma and other various lesions were cytology-negative, but plasmocytoma associated with intraoral ulceration revealed cytology-positive. 4) More keratinized cells or those with keratinizing tendency could be noticed in both edentulous and dentulous persons in smoker's group than in non-smoker's group. And it could be found that 15 cases, i.e. 62.5 per cent of 24 malignant cases were smokers. Cell Block Method Epithelial cells of both normal and pathologic oral cavity showed so marked morphologic changes that this method was not suitable for examination of cell elements. However, cells showed crowdings so that keratinizing tendency could be easily noticed at first sight by the difference of staining and the tumor cells could be distinctly observed. Membrane Filter Method No morphologic change could be seen and it was considred to be a useful method of diagnosis of malignancy, although cells overlapped each other. As a conclusion examination by centrifugation of the mouth washings and graglings was easy to collect cells, gave little irritation to the tissue and was a simple technic. It also could be repeated many times so that it was a very satisfactory method in cases of the following subjects: observation of postoperative progress, for example when the remnant of malignant tissue was suspected, examination of the cells after radiation therapy, early discovery of recurrence and examination of extensive lesions of the oral mucosa. en-copyright= kn-copyright= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=”’ÎD•v kn-aut-sei=”’Î kn-aut-mei=D•v aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=6059 end-page=6067 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ôò•À‚Ñ‚ÉŠÜšu‚É‚æ‚éŒûo”—£×–E‚ÉŠÖ‚·‚錤‹† ‘æ1•Ò ³íŒûo”—£×–EŠw en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=”’ÎD•v kn-aut-sei=”’Î kn-aut-mei=D•v aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=9-2 article-no= start-page=5911 end-page=5920 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on Acatalasemia from the Viewpoint of Oral Surgery I. Exfoliative Cytology kn-title=–³ƒJƒ^ƒ‰[ƒ[ŒŒ‰tÇ‚É‚¨‚¯‚鎕‰ÈŠw“IŒ¤‹† I. ”—£×–EŠw“IŒŸõ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Exfoliative cytologic findings of the oral mucosa in three cases of Acatalasemia (Takahara's disease) were investigated by means of Papanicolaou's method. Three cases were sisters of the same family, 19, 22, and 15 years of age. Oroantral fistula was noticed in the left molar area in Case 2 and Case 3 complained of loosening of anterior lower teeth with marginal gingivitis in the left lower molar ares. Smears were prepared by the following technics: 1) Scraping four different areas of the oral mucosa---hard palate, gingiva, radix linguae and buccal mucosa without causing bleeding. 2) Sediment taken from centrifuged mouth washings by physiologic saline solution. 3) Cells caught by membrane filter or both of them. All the smears were stained by Papanicolaou's technic and histologic examination of the gingiva was made in comparison with cytologic smears in Case 3. Thus keratinization of the epithelial cells were studied. 1) Keratinizing tendency was the same as those of normal mucosa in Cases 1 and 3. In the ulcerating area of Case 3 keratinized cells showed an increase as healing was going on, while they showed a marked decrease in Case 2, which might be due to the decrease of local resitance associated with ulcerative changes and the influence of partial denture. 2) Exfoliated cells of the whole oral mucosa in case of mouth washings Cases 1 and 3 showed the same findings as normal cases and Case 2 showed a marked decrease of keratinized cells. These findings were same as those of four different areas of the oral mucosa. 3) Gingiva of Case 3 showed little difference from normal mucosa in histopathologic findings. en-copyright= kn-copyright= en-aut-name=WatanabeYoshio en-aut-sei=Watanabe en-aut-mei=Yoshio kn-aut-name=“n•Ó‹`’j kn-aut-sei=“n•Ó kn-aut-mei=‹`’j aut-affil-num=1 ORCID= en-aut-name=MatsuiToshiyuki en-aut-sei=Matsui en-aut-mei=Toshiyuki kn-aut-name=¼ˆä?s kn-aut-sei=¼ˆä kn-aut-mei=?s aut-affil-num=2 ORCID= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=”’ÎD•v kn-aut-sei=”’Î kn-aut-mei=D•v aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=6-2 article-no= start-page=3419 end-page=3423 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590515 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship of Centrifuging Round to Disintegration of the Exfoliated Cells in Mouth Washings kn-title=ŠÜšu‰t’†‚Ì”—£×–E‚Ì”j‰ó‚Ɖ“S’¾“b‚̉ñ“]”‚Æ‚ÌŠÖŒW en-subtitle= kn-subtitle= en-abstract= kn-abstract=No study has been found on exfoliated cells in the mouth washings, while some have been made on exfoliative cytology of the mouth. For the purpose of investigation of exfoliated epithelial cells in the mouth washings by physiologic saline solution, preliminary study was made on effective factors in centrifuging rounds and time, staining, and changes of cell morphology by the use of mouth washings taken from the normal oral cavity with healthy teeth. Mouth washings were centrifuged for 5, 10, or 30 minutes at 1,000 r.p.m., 2,000 r.p.m. or 3,000 r.p.m. Washings were mixed immediately with 50 per cent alcohol or 95 per cent alcohol in comparison with those mixed with no alcohol. Each of materials was kept under the room temperature or in an incubator and examined consecutively concerning staining effect and changes of cell morphology. The results obtained are as follows: 1. The stable condition in staining effect and cell morphology was obtained in case of mixing with an equal quantity of 50 per cent alcohol immediately after mouth washings were taken and of 10-minute centrifugation at 2,000 r.p.m. And these smears could be stained and differentiated even 48 hours later in stable conditions. 2. Leucocytes were liable to be disintegrated more than 30 minutes after materials had been taken, while epithelial cells were not disintegrated. 3. When no alcohol was mixed, staining effect decreased rapidly 24 hours later, cell disintegration was marked and cell count could not be done successfully. en-copyright= kn-copyright= en-aut-name=ShiraishiYoshio en-aut-sei=Shiraishi en-aut-mei=Yoshio kn-aut-name=”’ÎD•v kn-aut-sei=”’Î kn-aut-mei=D•v aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=9-10 article-no= start-page=1167 end-page=1173 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199010 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Electron beam therapy in carcinoma of the buccal mucosa kn-title=–j”S–ŒŠà‚ɑ΂·‚é“dŽqüŽ¡—Ö@‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects including, stomatitis and dermatitis are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. en-copyright= kn-copyright= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=’†‹Ë‹`’‰ kn-aut-sei=’†‹Ë kn-aut-mei=‹`’‰ aut-affil-num=1 ORCID= en-aut-name=MiyakeHideaki en-aut-sei=Miyake en-aut-mei=Hideaki kn-aut-name=ŽO‘î‰pº kn-aut-sei=ŽO‘î kn-aut-mei=‰pº aut-affil-num=2 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=3 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=ŽOã‘×—² kn-aut-sei=ŽOã kn-aut-mei=‘×—² aut-affil-num=4 ORCID= en-aut-name=InamuraKeiji en-aut-sei=Inamura en-aut-mei=Keiji kn-aut-name=ˆî‘ºŒ\Ži kn-aut-sei=ˆî‘º kn-aut-mei=Œ\Ži aut-affil-num=5 ORCID= en-aut-name=MimuraSeiichi en-aut-sei=Mimura en-aut-mei=Seiichi kn-aut-name=ŽO‘º½ˆê kn-aut-sei=ŽO‘º kn-aut-mei=½ˆê aut-affil-num=6 ORCID= en-aut-name=OhkawaYoshihiro en-aut-sei=Ohkawa en-aut-mei=Yoshihiro kn-aut-name=‘åì‹`O kn-aut-sei=‘åì kn-aut-mei=‹`O aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=’|“c–FO kn-aut-sei=’|“c kn-aut-mei=–FO aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=9 ORCID= en-aut-name=FujikiTomokazu en-aut-sei=Fujiki en-aut-mei=Tomokazu kn-aut-name=“¡–Ø’mˆê kn-aut-sei=“¡–Ø kn-aut-mei=’mˆê aut-affil-num=10 ORCID= en-aut-name=KishiKanji en-aut-sei=Kishi en-aut-mei=Kanji kn-aut-name=ŠÝŠ²“ñ kn-aut-sei=ŠÝ kn-aut-mei=Š²“ñ aut-affil-num=11 ORCID= en-aut-name=ChiharaNaoto en-aut-sei=Chihara en-aut-mei=Naoto kn-aut-name=猴’¼l kn-aut-sei=猴 kn-aut-mei=’¼l aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—Ã’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆã—Ã’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆã—Ã’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽËüˆãŠw‹³Žº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽËüˆãŠw‹³Žº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”Ž•‰È•úŽËüŠwuÀ affil-num=11 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”Ž•‰È•úŽËüŠwuÀ affil-num=12 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”‘æ“ñŒûoŠO‰ÈŠwuÀ en-keyword=–j•””S–ŒŠà kn-keyword=–j•””S–ŒŠà en-keyword=“dŽqüŽ¡—à kn-keyword=“dŽqüŽ¡—à en-keyword=Œã•ûŽU—ü kn-keyword=Œã•ûŽU—ü en-keyword=mouthpiece kn-keyword=mouthpiece END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È—Õ°‚É‚¨‚¯‚銴õ—\–h‘ÎôˆÓŽ¯‚Æs“®‚ɂ‚¢‚Ä‚ÌŒ»ó‚Ɖۑè@|–^Œ§Ž•‰È‰q¶Žm‰ï‰ïˆõ‚ɑ΂·‚éˆÓŽ¯’²¸‚©‚ç| en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WatanabeAkari en-aut-sei=Watanabe en-aut-mei=Akari kn-aut-name=“n•ÓŽé— kn-aut-sei=“n•Ó kn-aut-mei=Žé— aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue= article-no= start-page=31 end-page=35 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=200209 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Evaluation of Availability of New Experiment Technique for Cervical Spinal Cavity Administration in Rats -Examination by Behavioral Pharmacological Study of Inducing Anesthetic Potentiation- kn-title=V‚½‚ÈŽÀŒ±Žè‹ZEƒ‰ƒbƒgŒz•”‘o“à“Š—^–@‚Ì—L—p«‚Ì•]‰¿\–ƒŒ‘‹­ì—p‚É‚æ‚és“®–ò—Šw“IŽŽŒ±‚Å‚ÌŒŸ“¢\ en-subtitle= kn-subtitle= en-abstract= kn-abstract=ƒ‰ƒbƒg‚Ìd¥ƒNƒ‚–Œ‰ºo“à‚Ö‚Ì“Š—^•û–@‚Æ‚µ‚Ăͤ]—ˆ‚©‚çƒJƒe[ƒeƒ‹Ý’u‚É‚æ‚é‘å‘…“à“Š—^–@‚ª”Ä—p‚³‚ê‚Ä‚¢‚é¡‚µ‚©‚µ¤‚±‚ê‚ç‚Ì‘å‘…“à“Š—^–@‚ͤ“Š—^‘O‚ÉŽèp‚È‚Ç‚ÌŽ–‘Oˆ’u‚â‰ñ•œ‚ÌŽžŠÔ‚ª•K—v‚È‚±‚ƂȂǂ̧–ñ‚ª‚ ‚邽‚ß,‘¬‚â‚©‚É“Š—^‚ðŠJŽn‚·‚邱‚Æ‚â’ZŽžŠÔ‚É‘½”‚̃‰ƒbƒg‚Ö“Š—^‚·‚邱‚Æ‚È‚Ç‚ª¢“ï‚Å‚ ‚é¡‚»‚±‚Ť‰äX‚̓‰ƒbƒg‚̌㓪•”‚©‚çŒo”ç“I‚ÉŒz•”‘o“à‚Öúj‚·‚é“Š—^–@‚Å‚ ‚éŒz•”‘o“à“Š—^–@‚ðŠJ”­‚µ‚½¡¡‰ñ‚ͤ‚»‚Ì—L—p«‚𖃌–ò‚âÖ°“±“ü܂̃XƒNƒŠ[ƒjƒ“ƒO‚É—p‚¢‚ç‚ê‚é–ƒŒ‘‹­ì—p‚É‚æ‚茟“¢‚ðs‚Á‚½¡–ƒŒ‘‹­ì—p‚͉–Ž_ƒPƒ^ƒ~ƒ“‚È‚ç‚тɃyƒ“ƒgƒoƒ‹ƒrƒ^[ƒ‹ƒiƒgƒŠƒEƒ€‚ð—p‚¢‚Ĥƒ`ƒIƒyƒ“ƒ^[ƒ‹ƒiƒgƒŠƒEƒ€–ƒŒ‘‹­ì—p‚É‚æ‚ès‚Á‚½¡‚»‚ÌŒ‹‰Ê¤Œz•”‘o“à“Š—^–@‚Í‘å‘…“à“Š—^–@‚É”ä‚פƒXƒgƒŒƒX–³‚­“Š—^‚Å‚«‚邱‚Æ¡‚·‚łɔėp‚³‚ê‚Ä‚¢‚é‘å‘…“à“Š—^–@“Š‚Æ“¯—l‚Ì–ò—Šw“I•]‰¿‚ª“¾‚ç‚ꂽŽ–‚È‚Ç‚©‚礌z•”‘o“à“Š—^–@‚Í‘å‘…“à“Š—^–@‚É‘ã‚í‚郉ƒbƒg‚Ìd¥ƒNƒ‚–Œ‰ºo“à‚Ö‚Ì“Š—^•û–@‚Æ‚µ‚Ẳ”\«‚ªŽ¦´‚³‚ꂽ¡ en-copyright= kn-copyright= en-aut-name=MuranakaKiyoshi en-aut-sei=Muranaka en-aut-mei=Kiyoshi kn-aut-name=‘º’†´Žu kn-aut-sei=‘º’† kn-aut-mei=´Žu aut-affil-num=1 ORCID= en-aut-name=SagaraEiji en-aut-sei=Sagara en-aut-mei=Eiji kn-aut-name=²‰Á—ljpŽ¡ kn-aut-sei=²‰Á—Ç kn-aut-mei=‰pŽ¡ aut-affil-num=2 ORCID= en-aut-name=KurabayashiYuzuru en-aut-sei=Kurabayashi en-aut-mei=Yuzuru kn-aut-name=‘q—Ñ÷ kn-aut-sei=‘q—Ñ kn-aut-mei=÷ aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Š”Ž®‰ïŽÐƒAƒjƒ}ƒ‹ƒPƒA affil-num=2 en-affil= kn-affil=‹ãBŽ•‰È‘åŠw“®•¨ŽÀŒ±Ž{Ý affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®“®•¨ŽÀŒ±Ž{Ý END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=5 article-no= start-page=211 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=1956 dt-pub=19560531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The statistical observations of the out-patients and in-patients during five years since the opening of the Department of Oral Surgery, Okayama University Medical School kn-title=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³ŽºŠJu5ƒP”NŠÔ‚ɉ—‚¯‚éŠO—ˆŠ³ŽÒ•À‚Ñ‚É“ü‰@Š³ŽÒ‚Ì“Œv“IŠÏŽ@ en-subtitle= kn-subtitle= en-abstract= kn-abstract=The statistic observations were made about the inpatients and out-patients of the department of oral surgery, okayama university medical school during full five years from July in 1950 to June in 1955. The out-patients were classified into those of inflammation (pulpitis and gingivitis excepted), of caries (which was divided into what needed canal treatment and what was not so serious), of pyorrhea alveolaris, of gingivitis, of tumour, and of other diseases, and then each disease group was observed according to the difference year, season, tooth, sex, age, and occupation. Thereby, comparatively remarkable, interesting, statistical, numeral values were not only obtained concerning to each disease, but also the characteristics of the department of oral surgery of the attached hospitals of our government universities were apparently recognized here also. As the total number of the in-patients was only 237, the detailed statistical report being reserved, they were observed only according to the difference of year and disease. Thereby, inflammation and tumour were so many that they occupied about 80% of the number of all the in-patients. en-copyright= kn-copyright= en-aut-name=FujiokaYukio en-aut-sei=Fujioka en-aut-mei=Yukio kn-aut-name=“¡‰ªK—Y kn-aut-sei=“¡‰ª kn-aut-mei=K—Y aut-affil-num=1 ORCID= en-aut-name=OnoHajime en-aut-sei=Ono en-aut-mei=Hajime kn-aut-name=¬–ìˆê kn-aut-sei=¬–ì kn-aut-mei=ˆê aut-affil-num=2 ORCID= en-aut-name=NishijimaKatsumi en-aut-sei=Nishijima en-aut-mei=Katsumi kn-aut-name=¼“ˆŽ–¤ kn-aut-sei=¼“ˆ kn-aut-mei=Ž–¤ aut-affil-num=3 ORCID= en-aut-name=KagawaGaiji en-aut-sei=Kagawa en-aut-mei=Gaiji kn-aut-name=ìŠM“ñ kn-aut-sei=ì kn-aut-mei=ŠM“ñ aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=2829 end-page=2884 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Absorption Activity of the Oral Mucosa kn-title=Œûo”S–Œ‚Ì‹zŽû”\‚ÉA‚¢‚Ä en-subtitle= kn-subtitle= en-abstract= kn-abstract=By the use of trypan blue, i.e. lipoid insoluble acid stain, in order to make observation of absorption activity of the oral mucosa, animals' mucosa with rapid absorption activity, its location, absorbing process, and absorbing conditions were investigated. Then clinical and biological observation on absorption of hormone of the salivary gland was tried. ‡T. Mixture containing equal parts of 1 per cent solution of trypan blue and saturated sodium bicarbonate solution was dropped and painted over the normal oral mucosa of various kinds of animals, such as dog, cat, hamster, albino rat, chicken, elaphis virgatus, lizard, rana esculenta, eft, and crusian and absorption of the solution was observed. The results obtained were as follows: 1) Absorption varied according to the kinds of animals. 2) In general absorption of the lower verbetrata was more remarkable than that of mammals and birds. 3) In mammals that of dogs was more marked than that of cat, hamster and albino rat. 4) In dogs marked absorption was seen in buccal and sublingual mucosa, particularly at the sublingual and parotid salivary papillae and their surrounding areas. 5) In albino rats absorption was made at the hard palate corresponding to the tip of the tongue. ‡U. In premature dogs it was equal to that of mature dogs. ‡V. No absorption was seen in the oral mucosa of the dog's and rabbit's fetus, while slight one was seen around the erupted teeth of the guinea-pig's fetus. ‡W. T.B. was not introduced into the ep. cells of rabbit's oral mueosa in case of vital staining. ‡X. The effects of various factors on T.B. absorption of the oral mucosa in dogs' experiments were as follows: Absorption-stimulating factors are, local thermal stimulation, Grace helio lamp irradiation. roentgen irradiation of amount of 60 r to 100 r, radium irradiation of amount of 33 mg. h, to 66 mg. h., intracranial amputation of maxillary and mandibular divisions of trigeminal nerve just after the procedure. and local injection of Teabrom (T.E.A.B.), in the early stage of injection, while absorption-inhibiting factor was local cold stimulation and no absorption was stimulated in case of anemia of the head following ligation of the common carotid artery. ‡Y. Parotin and Saliva-parotin, i.e. hormone of the salivary gland was painted over the oral mueosa of man, clog and rabbit. The results obtained were as follows: 1) Leucocytosis was noticed in cases of dog (1.2~5.0 mg./kg. of Parotin administered) and man (0.2~0.4 mg./kg. of Parotin or 0.1-0.2 mg./kg. of Saliva-parotin administered), 2) decrease of serum Ca. and leucocytosis in case of rabbit (1.0-5.0 mg./kg. of Parotin and Saliva-parotin administered), and 3) stimulated calcification of dentine in case of rabbit (5 mg./kg. of Parotin administered). These results Will suggest us the following factors as those effecting on absorbing mechanism of the oral mueosa, especially of the epithelium: 1) resistance, 2) intensity of surface tension, 3) intercellular density, 4) characteristics of chemical substances and solvent, and 5) special vital function of the cells. en-copyright= kn-copyright= en-aut-name=IdeiKiyoo en-aut-sei=Idei en-aut-mei=Kiyoo kn-aut-name=oˆä´—Y kn-aut-sei=oˆä kn-aut-mei=´—Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=4 article-no= start-page=1191 end-page=1215 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on the Mottled Deciduous Tooth kn-title=“ûŽ•”ÁóŽ•‚ÌŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Attention has been paid to the mottled tooth since the report of Black and McKay in 1916. Thereafter the developing mechanism of mottled teeth has been made clear to some extent by many examinations and studies, but the majority of them is that of the permanent tooth and very few works have been made on the deciduous tooth. What these few works agree in their opinions with each other is that incidence of mottled deciduous teeth is lower than that of permanent ones, but the reason for this difference is still in the stage of speculation. The results of clinical and experimental studies on the mechanism of development of mottled deciduous teeth are described in this paper. Material and Methods: The Th-Neo-Thorin Method was used for determination of fluorine. All the materials used were distilled and only the fluorine ion was isolated. 1) Numerous cases of mottled deciduous teeth were discovered when investigation of mottled teeth had been carried out in Tomita District, Tamashima City and Konko Town in Okayama Pref. in 1953. The results obtained from the studies on the relationship between their incidence and caries of deciduous teeth and on determination of the fluorine content in drinking water are as follows: a) Average number of the persons with mottled teeth was 47.84 per cent in the permanent teeth and 15.23 per cent in the deciduous teeth, in the ratio 3 to 1. And the degree of mottled teeth was M(1) in most cases and M(2) in few cases and no M(3) could be found. b) Minimal threshold of fluorine in the incidence of mottled teeth was approxiamtely 1.0 ppm. in the deciduous teeth, while 0.5 ppm. of fluorine caused mottled teeth of degree of M(1). c) Caries incidence of the deciduous teeth was as low as that of the permanent teeth; and caries incidence in case of mottled deciduous teeth was lower than that in case of permanent ones. 2) The following experiments were performed for the purpose of investigating the role the placenta played in the fluorine metabolism during pregnancy: First, the fluorine content in the placenta of pregnant women and in the drinking water taken by them selves during the pregnancy were determined both in fluorine and non-fluorine districts. Then oral examinations of the children of the mothers in the fluorine district were conducted. And the rationship of incidence of the mottled deciduous teeth to the content of fluorine in the placenta and in the drinking water was investigated and the fluorine content of the deciduous teeth was determined at the same time. The results obteined were as follows: a) When the mother took a large amount of fluoride, some of fluorine was retained in her placenta, while the rest pessed through the placenta and had an effect on the embryo. b) The higher was the content of fluorine in drinking water, the larger was the amount of fluorine retained in the placenta. c) A small amount of fluorine could be recognized in the control placenta taken from the non-fluorine district. d) Incidence of mottled deciduous teeth was dependent upon the fluorine content of drinking water. e) The larger the content of fluorine in drinking water, the more frequently seen the incidence of mottled deciduous teeth with its minimal threshold of 1.0 ppm. f) Fluorine of 334.4 ppm. on average was contained in the mottled deciduous teeth, i.e. about one third of fluorine in the mottled deciduous teeth. 3) The following animal experiments were performed in order to confirm those results mentioned above in human: Rabbits were used as experimental animals to investigate what amount of fluorine was retained in the placenta and to what extent it was transmitted to her embryo and, moreover, to determine whether there was any limit in the retention of fluorine within the placenta. a) When 0.5 mg./kg. or 1.0 mg/kg. of NaF was administered, no significant change was noticed in the fluorine content of the placenta as compared with that of the control, but maked retention of fluorine was seen, when 5.0 mg./kg. or more of NaF was given. b) When a large amount of NaF, ranging 10.0 mg./kg. to 20.0 mg./kg. was administered, fluorine passed through the placenta and was transmitted to the embryo. From the results obtained by these experiments it could be concluded that the placenta plays a definite role in fluorine metabolism during the pregnancy and its retention has an influence on the incidence of mottled deciduous teeth. en-copyright= kn-copyright= en-aut-name=WatanabeShimpei en-aut-sei=Watanabe en-aut-mei=Shimpei kn-aut-name=“n•ÓM•½ kn-aut-sei=“n•Ó kn-aut-mei=M•½ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=407 end-page=423 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Caries Incidence in the First Molar in Relation with Amount of Sugar Consumption on Primary School Children in Kyoto kn-title=‹ž“sŽs¬ŠwZŽ™“¶‘æˆê‘å‰PŽ•‚ÌêšI”­•a‚Æ»“œÁ”ï—Ê‚Æ‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=The relation between caries incidence and sugar consumption was cleared up by Takeuchi and Takahashi with the material of primary school children in Tokyo under the view point of the dental caries that should be observed by the rate of caries incidence as "one tooth as unit" and during a limited period, because the caries develop on the tooth as unit and never be healed spontaneously. The author, for the supplement study, observed the relation between sugar consumption and the rate of caries incidence during a year with a Cohort observation of the cases and analysed a pattern of the caries incidence in the first molar of 10,553 chidren who were born between 1924 and 1946, admitted into a school between 1931 and 1953 of 14 primary shools in Kyoo. The results were as follows: (1) Accumulated sugar consumption during the maturation period of teeth has only slight influence upon caries incidence.(2) The relation between sugar consumption for a year of new caries incidence in the first molar and the rate of new caries incidence for a year are extremely close and correlation coefficient of the average rate of caries incidence during 6-11 years of age to sugar consumption are: for example, in the lower first molar the year of the new caries incidence, the year before, and the year before last are respectively 0.8, 0.8 and 0.7. Also it was presumed that the type of quantitative relation on the semi-log graph shows a almost straight line. On this point this is almost as same as a results of Takeuch and Takahashi theoretically but it shows a little more slow curve and a smaller number. (3) With the materials during the years before the world war ‡U. I had made an age pattern of the rate of caries incidence in the first molar for 6-11 years of age. Using this pattern, I drew the model picture of the rate of caries incidence for a Cohort of which had a change of sugar consumption during the year. I had learned that it is possibly similar to the picture of the caries incidence for a year, which is drew with real Cohort. According to this result, with the model picture, I had learned the caries incidence for a year has extremely close relation with the sugar consumption during the year. Also it is presumed that an influence of the caries incidence on the individual tooth will always show a same age pattern without an influence of the sugar consumption. en-copyright= kn-copyright= en-aut-name=KoikeHiromu en-aut-sei=Koike en-aut-mei=Hiromu kn-aut-name=¬’rO kn-aut-sei=¬’r kn-aut-mei=O aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=“Œ‹žŽ•‰È‘åŠw‰q¶Šw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=387 end-page=406 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Histamine Content of the Saliva kn-title=‘Á‰tƒqƒXƒ^ƒ~ƒ“ŠÜ—Ê‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=A number of work on the saliva has been made by many authors, but chemical investigations particuarly on histamine of the saliva are few. Only those by Feldberg, Kamenowa, Sanders and Ungar et al. could be found. However, there has been no study on the histamine content of saliva at the onset of diseases in the oral cavity and its fluctuation at various kinds of surgery. Now quantiative determination was made on histamine content of the saliva in normal and pathological conditions of the oral cavity, and the relationship between the histamine content and the findings of exfoliative cytology was also investigated. One hundred and forty-five patients were examined: 46 of normal healthy control, 26 of acute inflammation, 37 of chronic inflammation, 6 of chronic non-inflammatory lesion, and 30 of minor surgery. Parotid saliva collected by Umemoto-Kakudo's Aspirator and mixed resting saliva were used as test materials. Assay of histamine was made by biological determination by means of Magnus' Apparatus after extraction of histamine by Code's Methode and then Mayeda's Method by neoantsrgan was adopted. In normal healthy controlshistamine contents of the parotid saliva and the mixed saliva were 0.015}0.002 ƒÊg/c.c. and 0.034}0.003 ƒÊg/c.c. respectively, which were almost equal to those in cases of slight degree of caries or edentulous jaws. In acute inflammation they were 0.036}0.002 ƒÊg/c.c. and 0.122}0.016 ƒÊg/c.c.. Histamine in the mixed saliva was markedly increased. In chronic inflammation they were 0.026}0.003 ƒÊg/c.c. and 0.119}0.019 ƒÊg/c.c.. Histaminee in the mixed saliva was increased especially in superficial and extensive lesions. In chronic non-inflammatory lesions they ware 0.018}0.004 ƒÊg/c.c., and 0.040}0.013 ƒÊg/c.c.. An increase of exfoliated epithelial cells, lescocytes, especially neutrophils, and bacilli were observed in acute inflammatory leasians with particulary high histamine content in the saliva. At the time of various procedures of oral surgery almost no change was observed in the parotid. saliva, while higher histamine content was noticed in the mixed saliva in major surgery than in minor one. Some considerations and discussions were made on the problems of histamine release and on the use of antihistamine preparations from the results obtained and the review of previous litrature. en-copyright= kn-copyright= en-aut-name=KobayashiToshiyuki en-aut-sei=Kobayashi en-aut-mei=Toshiyuki kn-aut-name=¬—Ñ•qs kn-aut-sei=¬—Ñ kn-aut-mei=•qs aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŒûoŠO‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=153 end-page=174 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Study on Vascularization of Blood Vessels in Postexodontic Wounds kn-title=”²Ž•‘n‚ÌŒŒŠÇV¶‚ÉŠÖ‚·‚éŽÀŒ±“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=By means of stereoscopic microscopy morphologic observation was made on vascularization of the blood vessels during the progress of postexodontic wound healing in 37 mature dogs. Imagawa's Guttapercha Infusion Method was adapted and macroscopic and radiographic observations were combined. In the wounds of 86 normal tooth extractions more remarkable vascularization could be noticed in the wound openings than in the apical areas in the early postexodontic stage. During the period of 10 to 14 days after extraction gingival mucosa covered the wound and capillary vascularizations were completed. Tendency of vascularization in postexedontic wound healing was fundamentally identical with those of descriptions by Clark and Akita: capillary buds formed, capillary loops newly developed, and then capillary networks completed. In the wounds of 50 extractions with apical foci experimentally made, capillary networks were dense in the wound opening, while they were loosened in the apical areas with a distinct difference between them in the early postexodontic stage. In the later stages, however, vascularization seemed to show a tendency of slight delay in comparison with normal healthy controls. In adittion, the effect of gauze packing and insertion of penicillin dental cone upon the wound healing was investigated. en-copyright= kn-copyright= en-aut-name=MakiRyoji en-aut-sei=Maki en-aut-mei=Ryoji kn-aut-name=^–Ø—º“ñ kn-aut-sei=^–Ø kn-aut-mei=—º“ñ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=53 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Exfoliative Cytology in Case of Leprosy ‡U. Oral Exfoliative Cytology in Leprosy kn-title=ᚊ³ŽÒ‚É‚¨‚¯‚éŒûo”—£×–EŠw“IŒ¤‹† ‘æ2•Ò ᚊ³ŽÒ‚ÌŒûo”—£×–EŠw en-subtitle= kn-subtitle= en-abstract= kn-abstract=In 152 in patients of the Aisei-en Leprosarium comparative studies were made on keratinization, degenerative changes, and N/C ratio with those in normal contorols. In addition, leprosy cells were proven on aspirated smear specimens taken from leproma of the face and upper extremity and their N/C ratio was compared with those of normal oral epithelial cells. 1. In leprosy keratinization was less and degenerative change of the exfoliated epithelial cells are higher than in normal. This could be proven histopathologically. 2. These changes did not show a difference between leprosy types. 3. The N/C ratio of exfoiiated epithelial cells showed no difference between normal and leprosy cases. 4. In detection of leprosy cells in aspiration the Ziehl-Neelsen method was highest in its detection percentage, which was followed by hematoxylin-eosion and Papanicolaou technics. 5. In leprosy cells the N/C ratio showed a decrease as the size of the cells showed an increase. 6. The N/C ratio showed a difference between normal epithelial cells and leprosy cells. 7. Papanicolaou technic can be considered a supplementary practical method in detection of leprosy cells in combination with Ziehl-Neelsen's method. en-copyright= kn-copyright= en-aut-name=HidakaToyozo en-aut-sei=Hidaka en-aut-mei=Toyozo kn-aut-name=“ú‚–L‘  kn-aut-sei=“ú‚ kn-aut-mei=–L‘  aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=1 article-no= start-page=45 end-page=51 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19591230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oral Exfoliative Cytology in Case of Leprosy I. Normal Exfoliative Cytology kn-title=ᚊ³ŽÒ‚É‚¨‚¯‚éŒûo”—£×–EŠw“IŒ¤‹† ‘æ1•Ò ³íl‚ÌŒûo”—£×–EŠw en-subtitle= kn-subtitle= en-abstract= kn-abstract=Exfoliated epithelial cells of oral mucosa of 15 normal healthy individuals were taken as smear specimens from various intraoal areas and their garglings and stained by Papanicolaou technic. Keratinization, degenerative changes, and nuclear-cytoplasmic ratio (N/C) were studied in each smear. 1. A decrease of keratinized epithelial cells was noticed in the order of hard palate, gingiva, base of the tongue and buccal mucosa. 2. In the garglings more non-keratinized and precornified blue and red cells were exfoliated, while fewer keratinized orange cells. 3. Areas of the cytoplasm and nncleus of the exfoliated epithelial cells were mearsured and classified into small, middle, and large cells. 4. The N/C ratio was noticed to show a decrease in th order of small, middle and large cells. en-copyright= kn-copyright= en-aut-name=HidakaToyozo en-aut-sei=Hidaka en-aut-mei=Toyozo kn-aut-name=“ú‚–L‘  kn-aut-sei=“ú‚ kn-aut-mei=–L‘  aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=1-3 article-no= start-page=1 end-page=24 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19630330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ELECTRON MICROSCOPIC STUDY ON THE ORAL EXFOLIATED EPITHELIAL CELLS kn-title=Œûo”—£×–E‚Ì“dŽqŒ°”÷‹¾“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electron microscopic observation was applied to both twenty cases of normal mucosa and eighteen cases of squamous cell carcinoma of the oral cavity and their exfoliative cytologic findings were investigated in comparison with the histologic findings. ‡T. TISSUE CELLS Desmosome, which are regarded as a universal structure of cohesion of epithelial cells, was much poorer in carcinoma cells than in normal ones and intercellular spaces displayed a marked variation in width in carcinoma tissue cells. Thus intercellular cohesion was morphologically very poor and loose in carcinoma. In both cells an intercellular border was distinct and no syncytium was found to be formed. Tonofilaments, which can be distinctly found in normal cells, could not be noticed and a higher development of endoplasmic reticulum and mitochondria was shown in carcinoma cells. However, the mitochondria of carcinoma cells was remarkable in degenerative findings and was larger in size than that of normal cells. There was a strong resemblance between basal cells of the normal tissue and carcinoma cells in an indefinite nuclear shap and a decrease of cytoplasmic: nuclear ratio. In carcinoma cells a fine structure of their nuclear membrane was well-preserved and their nucleoli could be remarkably noticed. ‡U. EXFOLATED CELLS In normal cells spinous processes of almost definite size and shape were extending regularly around them, while in carcinoma cells poorer processes of various shape and size were extending irregularly around them or sometimes they were missing. Mechanical destruction was particularly marked in the area of peripheral cytoplasm of normal cells of the deeper layer under the superficial spinous cell layer probably because of a tight intercellular cohesion. Generally speaking, findings of tonofilament, endoplasmic reticulum and mitochondria corresponded to those of tissue cells in both normal and carcinoma cells, while a slightly severer degeneration of intra-cytoplasmic organelles in exfoliated carcinoma cells could be noticed in comparison with carcinoma tissue cells. A fine structure was well-preserved in nuclei of carcinoma cells, but disintegration and disappearance of the nuclear membrane could be noticed in severely degenerated carcinoma cells and no thickening of the nuclear membrane could be found. From these results obtained the cytologic findings of the smear in Papanicolaou staining and electron microscopy were compared and discussed. en-copyright= kn-copyright= en-aut-name=KobayashiToshiro en-aut-sei=Kobayashi en-aut-mei=Toshiro kn-aut-name=¬—Ñ•q˜Y kn-aut-sei=¬—Ñ kn-aut-mei=•q˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=1-3 article-no= start-page=123 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=1962 dt-pub=19620330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Study on Capillary Vascularization in the Periodontal Tissue following Gingivectomy and Flap Operation kn-title=Ž•‘…”^˜RÇŽèp‘n‚ÌŒŒŠÇV¶‚ÉŠÖ‚·‚éŽÀŒ±“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Sixty five normal mature dogs weighing about 5 to 10Kg. fed on under the same condition were used. Gingivectomies were performed in the area of lower anterior teeth, while flap operation in the area of upper anterior teeth in the same dog. Healing process of operated gingivae was followed up during twenty-eight days after operative procedure. Imagawa's gutta percha perfusion methode was adopted for observation immdeiately after, 1day, 3, 7, 14, 21 and 28 days after operation consecutively, and then heads of sacrificed dogs were fixed in 10 percent formalin solution. Transparent specimens were prepared from the operated tissue for stereoscopic observation, while histologic specimens were stained with hematoxylin-eosin by a routine paraffin methode simultaneously. The result obtained were as followed: 1) Vascularization during wound healing of the operated gingiva, alveolar bone and periodontal membrane was fundamentally identical with description by Clark and Akita: new capillary loops which developed from capillary buds connected each other and built a capillary net work on the seventh days and then some capillaries disintegrated. 2) Clusters of capillary loops which developed in the granulation tissue were mainly supplied by the blood vessels of the periodontal membrane especially in the case of gingivectomy. Thus it could be considered that blood vessels of periodontal membrane would play the most important role in the blood supply for the newly formed gingiva in the early stage. 3) Newly formed blood vessles of the gingiva and periodontal membrane as well as branch vessels among of capillary loops were connected each other fourteen days after operation, 4) Reattachment of gingiva to cemeutum was noticed two weeks after operation. At this period capillary loops, which had developed in the wound of flap operations, built capillary net works at the area internal gingival epithelial margin (innere Saumepithel) and were shortened and came closer to cementum at the area where internal gingival epithelial margin attached. It would be considered that this process would stimulate the vitality of cementum and had some relationship in organic union of the connective tissue with cementum. 5) Wound healing was remarkably delayed at gingival papillae, where normal vascularization could not be noticed 28days after operation. Thus it would be better for us to use surgical packs after operation and gingival massage seemed to stimulate normal vascularization. en-copyright= kn-copyright= en-aut-name=SuzukiSatoshi en-aut-sei=Suzuki en-aut-mei=Satoshi kn-aut-name=—é–Ø’BŽu kn-aut-sei=—é–Ø kn-aut-mei=’BŽu aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž•‰ÈŠw‹³Žº END start-ver=1.4 cd-journal=joma no-vol=81 cd-vols= no-issue=3-4 article-no= start-page=135 end-page=141 dt-received= dt-revised= dt-accepted= dt-pub-year=1969 dt-pub=19690430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Report of Field Survey on Acatalasemia and Hypocatalasemia in 1966 and 1967 kn-title=º˜a41”N‚¨‚æ‚Ñ42”N“xAcatalasemia, Hypocatalasemia’²¸WŒv en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of field survey and family follow-up on acatalasemia and hypocatalasemia during the years of 1966 and 1967. Thirty-seven hypocatalasemias were seen in the tests of 11,875 individuals at Chiba Prefecture including the examinees tested in 1965. Thus, the rate of incidence at Chiba amounted to 0.31%. The test on students of Okayama University revealed two hypocatalasemias among 2,526 (0.08%). Oki Is. contained seven hypocatalasemias among their 4,831 school-children. And no hypocatalasemic individuals were found out among 2,682 inhabitants of Okinawa Is., Ryukyu. Formosa, however, showed rather high incidence rate such as 0.28%, 60 hypocatalasemias among 21,789 inhabitants. In 1966 and 1967, three acatalasemias of two families, one of them already reported in 1965, were added to the formerly known cases. Consequently, the total of reported acatalasemias were 93 cases of 44 families by the end of 1967. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=‚Œ´Ž •v kn-aut-sei=‚Œ´ kn-aut-mei=Ž •v aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=2 ORCID= en-aut-name=KoyamaTakashi en-aut-sei=Koyama en-aut-mei=Takashi kn-aut-name=¬ŽR‚Ži kn-aut-sei=¬ŽR kn-aut-mei=‚Ži aut-affil-num=3 ORCID= en-aut-name=KishimotoHiroyuki en-aut-sei=Kishimoto en-aut-mei=Hiroyuki kn-aut-name=ŠÝ–{_”V kn-aut-sei=ŠÝ–{ kn-aut-mei=_”V aut-affil-num=4 ORCID= en-aut-name=ChibaKazuo en-aut-sei=Chiba en-aut-mei=Kazuo kn-aut-name=ç—t˜a•v kn-aut-sei=ç—t kn-aut-mei=˜a•v aut-affil-num=5 ORCID= en-aut-name=SadamotoMasanori en-aut-sei=Sadamoto en-aut-mei=Masanori kn-aut-name=’å–{¹‹K kn-aut-sei=’å–{ kn-aut-mei=¹‹K aut-affil-num=6 ORCID= en-aut-name=TakehisaToru en-aut-sei=Takehisa en-aut-mei=Toru kn-aut-name=’|‹v‹œ kn-aut-sei=’|‹v kn-aut-mei=‹œ aut-affil-num=7 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=ŽO’J‹±•v kn-aut-sei=ŽO’J kn-aut-mei=‹±•v aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=9 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=Š}ˆä‰p•v kn-aut-sei=Š}ˆä kn-aut-mei=‰p•v aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=11 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠwl—Þˆâ“`ŠwŒ¤‹†Žº END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=7-8 article-no= start-page=259 end-page=265 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19710830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=º˜a43”N“x‚¨‚æ‚Ñ44”N“xAcatalasemia, Hypocatalasemia’²¸WŒv en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‚Œ´Ž •v kn-aut-sei=‚Œ´ kn-aut-mei=Ž •v aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=¬–ì“cŒ³’j kn-aut-sei=¬–ì“c kn-aut-mei=Œ³’j aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘哇º•v kn-aut-sei=‘哇 kn-aut-mei=º•v aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=Z“cºŽO kn-aut-sei=Z“c kn-aut-mei=ºŽO aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘êŒûs kn-aut-sei=‘êŒû kn-aut-mei=s aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=”öŠÖˆÀ‰p kn-aut-sei=”öŠÖ kn-aut-mei=ˆÀ‰p aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=Š}ˆä‰p•v kn-aut-sei=Š}ˆä kn-aut-mei=‰p•v aut-affil-num=8 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=9 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=10 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠwl—Þˆâ“`Œ¤‹†Žº END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=11-12 article-no= start-page=607 end-page=613 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19731230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Report of Field Survey on Acatalasemia and Hypocatalasemia in 1970 and 1971 kn-title=º˜a45”N“x‚¨‚æ‚Ñ46”N“xAcatalasemia,Hypocatalasemia’²¸WŒv en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authers reported the results of field survey on acatalasemia and hypocatalasemia during the years of 1970 and 1971. Six hypocatalasemias were seen in the tests of 3,593 individuals in several parts of Japan. No acatalasemic individuals were reported since 1968. Consequently, the total of reported acatalasemias were 96 cases of 46 families by the end of 1971. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=‚Œ´Ž •v kn-aut-sei=‚Œ´ kn-aut-mei=Ž •v aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=2 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=ŽO’J‹±•v kn-aut-sei=ŽO’J kn-aut-mei=‹±•v aut-affil-num=3 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=Š}ˆä‰p•v kn-aut-sei=Š}ˆä kn-aut-mei=‰p•v aut-affil-num=4 ORCID= en-aut-name=KawasakiKoichiro en-aut-sei=Kawasaki en-aut-mei=Koichiro kn-aut-name=ìèNˆê˜Y kn-aut-sei=ìè kn-aut-mei=Nˆê˜Y aut-affil-num=5 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=6 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=7 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠwl—Þˆâ“`Œ¤‹†Žº END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=7-8 article-no= start-page=527 end-page=534 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A report of field survey on acatalasemia and hypocatalasemia in 1972 and 1973 kn-title=º˜a47”N“x‚¨‚æ‚Ñ48”N“x Acatalasemia, Hypocatalasemia ’²¸WŒv en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of field survey on acatalasemia and hypocatalasemia during the year of 1972 and 1973. Seventeen hypocatalasemias were seen in the test of 7,475 individuals at Oahu Is. of Hawaii, U.S.A. Among them two Englishmen, one Portugese and three Filipinos were included. One new acatalasemia case was reported in 1972. Consequently, the total of reported acatalasemias were 97 cases of 47 families by the end of 1973. en-copyright= kn-copyright= en-aut-name=TanakaTohru en-aut-sei=Tanaka en-aut-mei=Tohru kn-aut-name=“c’†“O kn-aut-sei=“c’† kn-aut-mei=“O aut-affil-num=1 ORCID= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=‚Œ´Ž •v kn-aut-sei=‚Œ´ kn-aut-mei=Ž •v aut-affil-num=2 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=3 ORCID= en-aut-name=MasudaYu en-aut-sei=Masuda en-aut-mei=Yu kn-aut-name=‘“cŸà kn-aut-sei=‘“c kn-aut-mei=Ÿà aut-affil-num=4 ORCID= en-aut-name=ArakawaKiyoshi en-aut-sei=Arakawa en-aut-mei=Kiyoshi kn-aut-name=rì´ kn-aut-sei=rì kn-aut-mei=´ aut-affil-num=5 ORCID= en-aut-name=KasaiHideo en-aut-sei=Kasai en-aut-mei=Hideo kn-aut-name=Š}ˆä‰p•v kn-aut-sei=Š}ˆä kn-aut-mei=‰p•v aut-affil-num=6 ORCID= en-aut-name=TaniWataru en-aut-sei=Tani en-aut-mei=Wataru kn-aut-name=’JŒÝ kn-aut-sei=’J kn-aut-mei=ŒÝ aut-affil-num=7 ORCID= en-aut-name=ShibaKanji en-aut-sei=Shiba en-aut-mei=Kanji kn-aut-name=ŽÅŠ¤Ži kn-aut-sei=ŽÅ kn-aut-mei=Š¤Ži aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=9 ORCID= en-aut-name=OkamotoKaneko en-aut-sei=Okamoto en-aut-mei=Kaneko kn-aut-name=‰ª–{‚©‚ËŽq kn-aut-sei=‰ª–{ kn-aut-mei=‚©‚ËŽq aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰È‹³Žº affil-num=11 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠwl—Þˆâ“`Œ¤‹óŽº END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=3 article-no= start-page=183 end-page=187 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Two programs supporting community dentistry: an oral implant course and education about dysphagia rehabilitation kn-title=’nˆæ‚ÌŽ•‰Èˆã—Ê֌WŽÒ‚ɑ΂·‚éŽx‰‡\ŒûoƒCƒ“ƒvƒ‰ƒ“ƒguK‰ï‚ÆÛHE š‹‰ºƒŠƒnƒrƒŠƒe[ƒVƒ‡ƒ“‹³ˆç\ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AzumaTetsuji en-aut-sei=Azuma en-aut-mei=Tetsuji kn-aut-name=“Œ“NŽi kn-aut-sei=“Œ kn-aut-mei=“NŽi aut-affil-num=1 ORCID= en-aut-name=AriokaKyoko en-aut-sei=Arioka en-aut-mei=Kyoko kn-aut-name=—L‰ª‹Žq kn-aut-sei=—L‰ª kn-aut-mei=‹Žq aut-affil-num=2 ORCID= en-aut-name=ArakawaHikaru en-aut-sei=Arakawa en-aut-mei=Hikaru kn-aut-name=rìŒõ kn-aut-sei=rì kn-aut-mei=Œõ aut-affil-num=3 ORCID= en-aut-name=EgusaMasahiko en-aut-sei=Egusa en-aut-mei=Masahiko kn-aut-name=]‘³•F kn-aut-sei=]‘ kn-aut-mei=³•F aut-affil-num=4 ORCID= en-aut-name=KubokiTakuo en-aut-sei=Kuboki en-aut-mei=Takuo kn-aut-name=ŒE–Ø‘ñ’j kn-aut-sei=ŒE–Ø kn-aut-mei=‘ñ’j aut-affil-num=5 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name=X“cŠw kn-aut-sei=X“c kn-aut-mei=Šw aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@—\–hŽ•‰ÈŠw affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@@“ÁŽêŽ•‰È‘‡Ž¡—Õ”‘æ‚P‘‡f—ÃŽº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@ƒCƒ“ƒvƒ‰ƒ“ƒgĶ•â’ÔŠw affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠw•a‰@@“ÁŽêŽ•‰È‘‡Ž¡—Õ”‘æ‚P‘‡f—ÃŽº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@ƒCƒ“ƒvƒ‰ƒ“ƒgĶ•â’ÔŠw affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@—\–hŽ•‰ÈŠw en-keyword=’nˆæŽx‰‡ kn-keyword=’nˆæŽx‰‡ en-keyword=ŒûoƒCƒ“ƒvƒ‰ƒ“ƒg kn-keyword=ŒûoƒCƒ“ƒvƒ‰ƒ“ƒg en-keyword=ÛH kn-keyword=ÛH en-keyword=š‹‰ºƒŠƒnƒrƒŠƒe[ƒVƒ‡ƒ“ kn-keyword=š‹‰ºƒŠƒnƒrƒŠƒe[ƒVƒ‡ƒ“ END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=5-6 article-no= start-page=577 end-page=586 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Field survey of acatalasemia and hypocatalasemia from 1949 through 1985 kn-title=º˜a60”N‚Ü‚Å‚ÌAcatalasemia,Hypocatalasemia’²¸WŒv en-subtitle= kn-subtitle= en-abstract= kn-abstract=The authors reported the results of a field survey of acatalasemia and hypocatalasemia conducted from 1949 through 1985. Six families and eleven cases of acatalasemia and twelve hypocatalasemia cases were added to the statistics reported in 1976. As a result, the total number of reported acatalasemias became 108 cases in 53 families as of the end of 1985. en-copyright= kn-copyright= en-aut-name=TakaharaShigeo en-aut-sei=Takahara en-aut-mei=Shigeo kn-aut-name=‚Œ´Ž •v kn-aut-sei=‚Œ´ kn-aut-mei=Ž •v aut-affil-num=1 ORCID= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=2 ORCID= en-aut-name=MasudaYu en-aut-sei=Masuda en-aut-mei=Yu kn-aut-name=‘“cŸà kn-aut-sei=‘“c kn-aut-mei=Ÿà aut-affil-num=3 ORCID= en-aut-name=NishiokaKeiko en-aut-sei=Nishioka en-aut-mei=Keiko kn-aut-name=¼‰ªŒcŽq kn-aut-sei=¼‰ª kn-aut-mei=ŒcŽq aut-affil-num=4 ORCID= en-aut-name=NishizakiKazunori en-aut-sei=Nishizaki en-aut-mei=Kazunori kn-aut-name=¼è˜a‘¥ kn-aut-sei=¼è kn-aut-mei=˜a‘¥ aut-affil-num=5 ORCID= en-aut-name=SugiuraTomoaki en-aut-sei=Sugiura en-aut-mei=Tomoaki kn-aut-name=™‰Y—Fº kn-aut-sei=™‰Y kn-aut-mei=—Fº aut-affil-num=6 ORCID= en-aut-name=FurukawaKatsuro en-aut-sei=Furukawa en-aut-mei=Katsuro kn-aut-name=ŒÃ쟘N kn-aut-sei=ŒÃì kn-aut-mei=Ÿ˜N aut-affil-num=7 ORCID= en-aut-name=MizukoYukio en-aut-sei=Mizuko en-aut-mei=Yukio kn-aut-name=…‰ÍK•v kn-aut-sei=…‰Í kn-aut-mei=K•v aut-affil-num=8 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=9 ORCID= en-aut-name=OgataMasana en-aut-sei=Ogata en-aut-mei=Masana kn-aut-name=•û³–¼ kn-aut-sei=•û kn-aut-mei=³–¼ aut-affil-num=10 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”ŒöO‰q¶Šw‹³Žº affil-num=11 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠw“Ž¾Š³Œ¤‹†Šl—Þˆâ“`Šw•”–å END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=1-2 article-no= start-page=1 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of L-azetidine-2-carboxylic acid on (3)H-proline uptake into rat incisor dentin kn-title=ƒ‰ƒbƒgØŽ•Û‰åŽ¿‚É‚¨‚¯‚é(3)H-proline‚ÌŽæ‚èž‚Ý‚É‹y‚Ú‚·L-azetidine-2-carboxylic acid‚̉e‹¿ en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the present study the effect of L-azetidine-2-carboxylic acid on uptake of (3)H-proline into incisor dentin of young rats is investigated. For the experiment, (3)H-proline (50mCi/g) and L-azetidine-2-carboxylic acid (1mg/g) were simultaneously injected into rats. The first rat was killed 10min, the second one 30min, the third one 1hr, the fourth one 6hr, and the last one 24hr after the injection. The upper and lower incisors were used for light and electron microscopic autoradiography. In the control, the same procedure was performed but with an injection of 50mCi/g of (3)H-proline only. Quantitative analysis of (3)H-proline incorporation into dentin and pulp of the upper incisors was done and radioactivity was counted by a liquid scintillation-counter. In the control group, at 10 and 30min after the injection, grains were found in odontoblasts. At 1 and 6hr after the injection, they were distributed in the predentin, and the grains were in the dentin 24hr after the injection. In the treated group, on the other hand, grains were found in odontoblasts at 30min and 6hr. Moreover, the grains in the treated group were distributed rather sparsely. The result of the quantitative analysis by a liquid scintillation-counter indicated that the amount of (3)H-proline incorporated into dentin in the treated group was about one third of that in the control. No significant difference was found in the pulps between the treated and the control animals. en-copyright= kn-copyright= en-aut-name=NagaiHiroshi en-aut-sei=Nagai en-aut-mei=Hiroshi kn-aut-name=‰iˆäœA kn-aut-sei=‰iˆä kn-aut-mei=œA aut-affil-num=1 ORCID= en-aut-name=SuzukiKazunori en-aut-sei=Suzuki en-aut-mei=Kazunori kn-aut-name=—é–؈ꌛ kn-aut-sei=—é–Ø kn-aut-mei=ˆêŒ› aut-affil-num=2 ORCID= en-aut-name=SudoHiroko en-aut-sei=Sudo en-aut-mei=Hiroko kn-aut-name={“¡”ŽŽq kn-aut-sei={“¡ kn-aut-mei=”ŽŽq aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”Œûo‰ð–UŠw‘æ1uÀ affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”Œûo‰ð–UŠw‘æ1uÀ affil-num=3 en-affil= kn-affil=“Œ–kŽ•‰È‘åŠwŒûo‰ð–UŠw‘æ2uÀ en-keyword=ØŽ•Û‰åŽ¿ kn-keyword=ØŽ•Û‰åŽ¿ en-keyword=ƒI[ƒgƒ‰ƒWƒIƒOƒ‰ƒtƒB[ kn-keyword=ƒI[ƒgƒ‰ƒWƒIƒOƒ‰ƒtƒB[ en-keyword=proline analogue kn-keyword=proline analogue END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=2 article-no= start-page=121 end-page=129 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Œ»‘œ‰·“x‚¨‚æ‚ÑŽžŠÔ‚̃}ƒ“ƒ‚ƒtƒCƒ‹ƒ€“Á«‚É—^‚¦‚é‰e‹¿ kn-title=The Influence of Film Processing Temperature and Time on Mammographic film Characteristics en-subtitle= kn-subtitle= en-abstract=ƒtƒBƒ‹ƒ€ˆ—ðŒ‚É‚¨‚¢‚Ä,Œ»‘œ‰·“x‚ƈ—ŽžŠÔ‚ɑ΂·‚é‰e‹¿‚ð4Ží—ނ̃}ƒ“ƒ‚ƒOƒ‰ƒtƒB—pƒtƒBƒ‹ƒ€Konica New CM, Fuji UM-MA HC,Kodak Min-R M,v‘¬ˆ——pKodak EB/RA‚ɂ‚¢‚Ä’²‚ׂ½¡‚»‚µ‚Ä,”äŠrŠî€—p‚Æ‚µ‚Ä—¼–Ê“û܃tƒBƒ‹ƒ€Fuji UR-2‚ð—p‚¢‚½¡Š´ŒõŒv‚ŘIŒõ‚µ‚½ƒtƒBƒ‹ƒ€‚ðŒ»‘œ‰·“x28`36Ž,ˆ—ŽžŠÔ45`210•b‚ň—‚µ‚½¡“Á«‹Èü‚©‚瓾‚ç‚ꂽƒtƒBƒ‹ƒ€“Á«i•½‹ÏŠK’²“x,‘Š‘Ί´“x,ƒJƒuƒŠ”Z“xj‚ðˆÙ‚Ȃ錻‘œ‰·“x,Œ»‘œŽžŠÔ‚ɑ΂µ‚Ä•]‰¿‚µ‚½¡UR-2‚Í‚Ù‚Æ‚ñ‚lje‹¿‚ðŽó‚¯‚¸,ƒ}ƒ“ƒ‚ƒOƒ‰ƒtƒB—pƒtƒBƒ‹ƒ€‚Í,ƒJƒuƒŠ”Z“x‚ªã¸‚·‚邱‚Æ‚È‚­,Œ»‘œðŒ‚̉e‹¿‚ð‘å‚«‚­Žó‚¯‚½BNew CM, UM-MA HC,Min-R M‚ÍŒ»‘œ‰·“x‚Ìã¸,ˆ—ŽžŠÔ‚̉„’·‚É”º‚¢,•½‹ÏŠK’²“x‚Æ‘Š‘Ί´“x‚Í‘‰Á‚µ‚½¡‚µ‚©‚µ,New CM, UM-MA HC‚Ì36Ž,210•b‚Å‘‰Á‚ÍŒÀ“x‚É’B‚µ‚½¡EB/RA‚Ì•½‹ÏŠK’²“x‚͈ê’è‚Å,‘Š‘Ί´“x‚Í—¼–Ê“û܃tƒCƒ‹ƒ€‚Æ“¯ —l‚ɂ킸‚©‚È‘‰Á‚Å‚ ‚Á‚½¡‚±‚ê‚ç‚ÌŒ‹‰Ê‚Í,New CM, UM-MA HC, Min-R M‚É‚¨‚¢‚Ä,ˆ—ðŒ‚ð•Ï‰»‚³‚¹‚邱‚Æ‚É‚æ‚è,”픘’ጸ,ƒRƒ“ƒgƒ‰ƒXƒgŒüã‚ÉvŒ£‚Å‚«‚é‰Â”\«‚ðŽ¦´‚µ‚Ä‚¢‚½¡ kn-abstract=The influence for developing temperature and processing time within film processing conditions was investigated using four mammographic films, Konica New CM, Fuji UM-MA HC, Kodak Min-R M and Kodak EB/RA (for rapid system). And Fuji UR-2, a double-emulsion film, was used as a control. Those sensitometric strips exposed by a sensitometer were processed in the different combinations of developing temperatures ranging from 28 to 36Ž, processing times from 45 to 210 sec. Average gradient, relative speed and base plus fog obtained from the measured film characteristic curves were evaluated for the different developing temperatures and times. Fuji UR-2 was scarcely affected and mammographic films were greatly affected in the different combinations without an increase in base plus fog except EB/RA. In New CM, UM-MA HC and Min-R M, the average gradients and the relative speeds increased as the developing temperature was higher and the developing time was longer, but the increases were limit on the combination of 36Ž and 210 sec in New CM and UM-MA HC. In EB/RA, the average gradients were almost constant and the relative speeds increased slightly like the double-emulsion film. These results suggested that it would be possible to contribute to dose reduction and advancement of contrast in New CM, UM-MA HC and Min-R M by changing these processing parameters. en-copyright= kn-copyright= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=ŠÛŽR•q‘¥ kn-aut-sei=ŠÛŽR kn-aut-mei=•q‘¥ aut-affil-num=1 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=Œã“¡²’mŽq kn-aut-sei=Œã“¡ kn-aut-mei=²’mŽq aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=3 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=’†‹Ë‹`’‰ kn-aut-sei=’†‹Ë kn-aut-mei=‹`’‰ aut-affil-num=4 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=a’JŒõˆê kn-aut-sei=a’J kn-aut-mei=Œõˆê aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=6 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=’|“à’ms kn-aut-sei=’|“à kn-aut-mei=’ms aut-affil-num=7 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=–{“cv kn-aut-sei=–{“c kn-aut-mei=v aut-affil-num=8 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=‹g“c² kn-aut-sei=‹g“c kn-aut-mei=² aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=9 en-affil= kn-affil=L“‡Œ§—§•ÛŒ’•ŸŽƒ’ZŠú‘åŠw•úŽËü‹Zp‰ÈŠw‰È en-keyword=ƒ}ƒ“ƒ‚ƒOƒ‰ƒtƒB (Mammography) kn-keyword=ƒ}ƒ“ƒ‚ƒOƒ‰ƒtƒB (Mammography) en-keyword=Œ»‘œˆ—ƒpƒ‰ƒ[ƒ^ (Processing Parameter) kn-keyword=Œ»‘œˆ—ƒpƒ‰ƒ[ƒ^ (Processing Parameter) en-keyword=“Á«‹Èü (Characteristic Curve) kn-keyword=“Á«‹Èü (Characteristic Curve) en-keyword=•½‹ÏŠK’²“x (Average Gradient) kn-keyword=•½‹ÏŠK’²“x (Average Gradient) en-keyword=‘Š‘Ί´“x (Relative Speed) kn-keyword=‘Š‘Ί´“x (Relative Speed) END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=2 article-no= start-page=113 end-page=119 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Examination of density and mixing ratio of barium preparations, using an originally created phantom kn-title=Ž©ìƒtƒ@ƒ“ƒgƒ€‚É‚æ‚é—°Ž_ƒoƒŠƒEƒ€»Ü‚Ì”Z“x‹y‚Ѭ‡”ä‚ÌŒŸ“¢ en-subtitle= kn-subtitle= en-abstract=A phantom copied designs of coins was created with alginate dental impression material to establish a objective, simple and easy method for deciding density of barium sulfate suspensions which are used for stomach X-ray examination as contrast media. As a result of examining proper density (PD) of two kind of barium preparations with this phantom, in case of BARITOP P and BARICON MEAL, PD were almost shown by the next equation : PD(W/V%)=0.75C+165(C meant content of BARICON MEAL (%)). As BARICON MEAL resulted in hight contrast, it was thought to be suitable for a close examination. Mixture of BARITOP P and BARICON MEAL was thought to be suited to a routine examination becouse of wide permissible level of density. This phantom would be able to apply to the test of balium preparations, X-ray TV systems, screen/film systems and so on. kn-abstract=ˆÝ‡]üŒŸ¸‚É‘¢‰eÜ‚Æ‚µ‚Ä—p‚¢‚ç‚ê‚é—°Ž_ƒoƒŠƒEƒ€Œœ‘÷‰t‚Ì”Z“x‚ð,ŠÈ•Ö‚É,‹qŠÏ“I‚ÉŒˆ’è‚·‚é–Ú“I‚Å,Ž•‰È—pƒAƒ‹ƒMƒ“Ž_‰–ˆóÛÞ‚ð—p‚¢‚Ä,ƒRƒCƒ“‚Ì}•¿‚ðŽÊ‚µ‚Æ‚Á‚½ƒtƒ@ƒ“ƒgƒ€‚ð§ì‚µ‚½¡‚±‚ê‚ðŽg‚Á‚Ä“ñŽí—Þ‚Ì—°Ž_ƒoƒŠƒEƒ€»Ü‚Ì“K³”Z“x(PD)‚𒲂ׂ½Œ‹‰Ê,BARITOP P‚ÆBARICON MEAL‚ð’P‘Ì,Žá‚­‚ͬ‡‚µ‚½ê‡‚É‚Í,‚¨‚¨‚æ‚»,PD(W/V%)=0.75C+165(‚½‚¾‚µ,C‚ÍBARICON MEAL‚̬‡”ä(%))‚Æ‚È‚Á‚½¡‚Ü‚½,BARICON MEAL‚̓Rƒ“ƒgƒ‰ƒXƒg‚ª‚‚­,¸–§ŒŸ¸‚É—L—˜‚¾‚Æl‚¦‚ç‚ê,BARITOP P‚ÆBARICON MEAL‚𬇂·‚é‚Æ”Z“x‚Ì‹–—e”͈͂ªL‚ª‚邽‚ß,’Êí‚ÌŒŸ¸‚É“s‡‚ª‚æ‚¢‚Æl‚¦‚ç‚ꂽ¡X‚É,‚±‚̃tƒ@ƒ“ƒgƒ€‚ÍŠÈ•Ö‚É쬂·‚邱‚Æ‚ª‚Å‚«,‚µ‚©‚à,—°Ž_ƒoƒŠƒEƒ€Œœ‘÷ ‰t‚Æ‚Ìe˜a«‚à—Ç‚¢‚±‚Æ‚©‚ç,—°Ž_ƒoƒŠƒEƒ€»Ü‚â‡]üTV‘•’u‚Ì•]‰¿,‘Š´Ž†¥ƒtƒBƒ‹ƒ€Œn‚Ì•]‰¿“™‚É‚à‰ž—p‚Å‚«‚é‚Æl‚¦‚ç‚ꂽ¡ en-copyright= kn-copyright= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=a’JŒõˆê kn-aut-sei=a’J kn-aut-mei=Œõˆê aut-affil-num=1 ORCID= en-aut-name=MiyaharaTomonori en-aut-sei=Miyahara en-aut-mei=Tomonori kn-aut-name=‹{Œ´’q‘¥ kn-aut-sei=‹{Œ´ kn-aut-mei=’q‘¥ aut-affil-num=2 ORCID= en-aut-name=SumiKazuyuki en-aut-sei=Sumi en-aut-mei=Kazuyuki kn-aut-name=˜hŒ©˜aK kn-aut-sei=˜hŒ© kn-aut-mei=˜aK aut-affil-num=3 ORCID= en-aut-name=OkuraYasuhiko en-aut-sei=Okura en-aut-mei=Yasuhiko kn-aut-name=‘å‘q•Û•F kn-aut-sei=‘å‘q kn-aut-mei=•Û•F aut-affil-num=4 ORCID= en-aut-name=MiyakeKoichi en-aut-sei=Miyake en-aut-mei=Koichi kn-aut-name=ŽO‘î_ˆê kn-aut-sei=ŽO‘î kn-aut-mei=_ˆê aut-affil-num=5 ORCID= en-aut-name=OkudaKazuhiro en-aut-sei=Okuda en-aut-mei=Kazuhiro kn-aut-name=‰œ“c˜a—T kn-aut-sei=‰œ“c kn-aut-mei=˜a—T aut-affil-num=6 ORCID= en-aut-name=TandaniNobuyoshi en-aut-sei=Tandani en-aut-mei=Nobuyoshi kn-aut-name=’O’J‰„‹` kn-aut-sei=’O’J kn-aut-mei=‰„‹` aut-affil-num=7 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=8 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=Œã“¡²’mŽq kn-aut-sei=Œã“¡ kn-aut-mei=²’mŽq aut-affil-num=9 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=ŠÛŽR•q‘¥ kn-aut-sei=ŠÛŽR kn-aut-mei=•q‘¥ aut-affil-num=10 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=’†‹Ë‹`’‰ kn-aut-sei=’†‹Ë kn-aut-mei=‹`’‰ aut-affil-num=11 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=12 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=3 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=4 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=5 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=6 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=7 en-affil= kn-affil=iàj‘q•~¬l•aƒZƒ“ƒ^[•úŽËü•” affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=11 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=12 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=13 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽËüˆãŠw‹³Žº en-keyword=‘¢‰eÜ (contrast media) kn-keyword=‘¢‰eÜ (contrast media) en-keyword=—°Ž_ƒoƒŠƒEƒ€ (barium sulfate suspension) kn-keyword=—°Ž_ƒoƒŠƒEƒ€ (barium sulfate suspension) en-keyword=ˆÝXüŒŸ¸ (X-ray examination of the stomach) kn-keyword=ˆÝXüŒŸ¸ (X-ray examination of the stomach) en-keyword=ƒAƒ‹ƒMƒ“Ž_‰–ˆóÛÞ (alginate impression material) kn-keyword=ƒAƒ‹ƒMƒ“Ž_‰–ˆóÛÞ (alginate impression material) en-keyword=ƒtƒ@ƒ“ƒgƒ€ (phantom) kn-keyword=ƒtƒ@ƒ“ƒgƒ€ (phantom) END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue=2 article-no= start-page=75 end-page=81 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relative biological effectiveness (RBE) and potential leathal damage repair (PLDR) of heavy-ion beam kn-title=d—±Žqü‚̶•¨Šw“IŒø‰Ê”ä‚ÆöÝ«’vŽ€‘¹‚©‚ç‚̉ñ•œ en-subtitle= kn-subtitle= en-abstract=Relative biological effectiveness (RBE) and repair of potential lethal damage (PLDR) of NIH3T3 cells against heavy-ion radiation were studied. RBE of 150 KV X-rays and neutron estimated from LD(10) dose of dose response survival curves compared to (60)Co ƒÁ-ray were 1.26 and 2.44, respectively. RBE of 13, 20, 50, 90, 140, 150, 153, 200 keV/ƒÊm of LET of carbon beam were 1.41, 1.47, 2.22, 2.61, 2.61, 1.61, 2.05 and 1.57, respectively. Potential lethal damage repair (PLDR) after exposure to carbon beam was observed. The magnitude of PLDR of (60)Co ƒÁ-ray was the biggest. As for the carbon beam of LET of 13 keV/ƒÊm as well, PLDR were observed. PLDR decreased when LET of carbon beam grew big. kn-abstract=150KV Xü,’†«Žqü‹y‚Ñ’Y‘f(LET13, 20, 50, 90, 140, 150, 153, 200keV/ƒÊm)‚ðÆŽË‚µ‚½ƒ}ƒEƒXNIH3T3×–E‚̶‘¶—¦‹Èü‚ÌLD(10)‚©‚ç(60)CoƒÁü‚ɑ΂·‚鶕¨Šw“IŒø‰Ê”ä(RBE)‚ð‹‚ß‚½¡RBE‚Í150KV Xü‚Å‚Í1.26,’†«Žqü‚Å‚Í2.44,’Y‘fü(LET13, 20, 50, 90, 140, 150, 153, 200keV/ƒÊm)‚Å‚Í‚»‚ꂼ‚ê1.41, 1.47, 2.22, 2.61, 1.61, 2.05, 1.57‚Å‚ ‚Á‚½¡LET‚ÆRBE‚ÌŠÖŒW‚Å‚Í100keV/ƒÊm•t‹ß‚Ƀs[ƒN‚ð”F‚ß‚½¡150KVXü‚ÌLET‚Í13keV/ƒÊm,’†«Žqü‚ÌLET‚Í70keVƒÊm‚É‘Š“–‚µ‚½¡(60)Co ƒÁü‚ÌöÝ«’vŽ€‘¹‚©‚ç‚̉ñ•œ(PLDR)‚Í‘å‚«‚©‚Á‚½¡’Y‘fü(13keV/ƒÊm)ÆŽË‚Å‚àPLDR‚ªŠÏŽ@‚³‚ê‚邪LET‚ª‘å‚«‚­‚È‚é‚ÆPLDR‚ÍŒ¸­‚µ‚½‚ª,LET90keV/ƒÊm‚Ì’Y‘fü‚Å‚àPLDR‚ª”F‚ß‚ç‚ꂽ¡ÆŽËŽž‚Ì×–Eó‘Ô‚ÌŒŸ“¢‚Å‚Í‘BŠú‚Ì×–E‚ÌŠ´Žó«‚Í’èíŠú×–E‚ɔ䂵‹Í‚©‚É‚‚©‚Á‚½¡ en-copyright= kn-copyright= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=ìèË“ñ kn-aut-sei=ìè kn-aut-mei=Ë“ñ aut-affil-num=1 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=àF’JŒõˆê kn-aut-sei=àF’J kn-aut-mei=Œõˆê aut-affil-num=2 ORCID= en-aut-name=AsaumiJunichi en-aut-sei=Asaumi en-aut-mei=Junichi kn-aut-name=óŠC~ˆê kn-aut-sei=óŠC kn-aut-mei=~ˆê aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=¬¼‚ß‚®‚Ý kn-aut-sei=¬¼ kn-aut-mei=‚ß‚®‚Ý aut-affil-num=4 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=•“c¹G kn-aut-sei=•“c kn-aut-mei=¹G aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=6 ORCID= en-aut-name=FurusawaYoshiya en-aut-sei=Furusawa en-aut-mei=Yoshiya kn-aut-name=ŒÃàV‰À–ç kn-aut-sei=ŒÃàV kn-aut-mei=‰À–ç aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰È•úŽËü‹Zp‰ÈŠwêU affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰È•úŽËü‹Zp‰ÈŠwêU affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”Ž•‰È•úŽËüŠwuÀ affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”ˆãŠw‰È•úŽËüˆãŠwuÀ affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”ˆãŠw‰È•úŽËüˆãŠwuÀ affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”ˆãŠw‰È•úŽËüˆãŠwuÀ affil-num=7 en-affil= kn-affil=•úŽËüˆãŠwŒ¤‹†Š‰F’ˆ—±ŽqüŒ¤‹†ƒOƒ‹[ƒv en-keyword=PLDR kn-keyword=PLDR en-keyword=RBE kn-keyword=RBE en-keyword=Heavy-lon Radiation kn-keyword=Heavy-lon Radiation en-keyword=NIH3T3 Cells kn-keyword=NIH3T3 Cells END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=2 article-no= start-page=107 end-page=117 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ƒ}ƒCƒNƒƒRƒ“ƒgƒ[ƒ‰‚ð‘g‚Ýž‚ñ‚¾Ž•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg“®—h‘ª’è‘•’u‚ÌŠJ”­ kn-title=Development of a microcontroller-based dental implant movement checker en-subtitle= kn-subtitle= en-abstract=–{Œ¤‹†‚Ì–Ú“I‚ÍŽ•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg‚Ì“®—h‚ðŠÈˆÕ‚É‘ª’è‚Å‚«‚é‘•’u‚ÌŠJ”­‚Å‚ ‚é¡–{‘•’u‚Å‚Í‘ª’èƒvƒ[ƒu‚ňê’èU•‚ÌŽü”g”‚ðŽ•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg‚É—^‚¦¤‚»‚̉Á‘¬“xM†‚ðŒŸo‚·‚é¡‚»‚µ‚Ä–{Œ¤‹†‚ÅlŽ@‚µ‚½•]‰¿Šî€‚ÉŠî‚¢‚ÄIM’l‚ð•\Ž¦‚·‚é¡‚³‚ç‚ÉRigolac?‚âMolteno?‚ð—p‚¢¤ƒCƒ“ƒvƒ‰ƒ“ƒg‘Ì‚Ì’·‚³‚¨‚æ‚Ñ’¼Œa‚ð•Ï‚¦‚½ƒCƒ“ƒvƒ‰ƒ“ƒgƒ‚ƒfƒ‹‚ð컂µ‚½¡400Hz‚É‚¨‚¯‚郂ƒfƒ‹‚Ì‹@ŠBƒ‚ƒrƒŠƒeƒB‚ÆIM’l‚Ƃ̊Ԃɂͤ‚æ‚¢‘ŠŠÖ‚ªŒ©‚ç‚ꂽ(R(2)=0.92)¡IMƒ`ƒFƒbƒJ[‚ð—p‚¢¤ˆêl‚Ì‘ª’èŽÒ‚ªs‚Á‚½12‰ñ‚Ì‘ª’è‚É‚¨‚¢‚ĤƒCƒ“ƒvƒ‰ƒ“ƒg‚Ì“®—h‚ð”»•Ê‚·‚邱‚Æ‚ª‰Â”\‚Å‚ ‚Á‚½(P<0.01)¡‚Ü‚½4l‚Ì‘ª’èŽÒ‚É‚æ‚鑪’è‚Å‚Í,‚»‚Ì•½‹Ï’l‚ɑ΂µ‘ª’èŽÒŠÔ‚Ì—LˆÓ·‚ÍŒ©‚ç‚ê‚È‚©‚Á‚½(P<0.01)¡]‚Á‚ÄIMƒ`ƒFƒbƒJ[‚Í\•ª‚ÈM—Š«‚ð—L‚µ¤Ž•‰È—Õ°‚É—LŒø‚Å‚ ‚é‚Æl‚¦‚é¡ kn-abstract=The aim of this study was to develop a portable device (IM checker) for measuring dental implant mobility using a microcontroller. A constant amplitude and frequency vibration was applied to a dental implant model and the acceleration signal was detected using measuring probe. Then the IM score was obtained using the criteria developed in this study. We made several implant models of different implant lengths, diameters and material of Rigolac? or Molteno?. There was a linear relationship between mechanical mobility at 400 Hz of the models and the IM scores (R(2) = 0.92). The IM checker could discriminate the mobility of dental implant models in twelve measurements with P < 0.01. There was no significant difference in the means of the IM score measured by four operators with P < 0.01. The results indicated that the IM checker had sufficient reliability and could be available in dental clinics. en-copyright= kn-copyright= en-aut-name=Kusuma WijayaSastra en-aut-sei=Kusuma Wijaya en-aut-mei=Sastra kn-aut-name=ƒNƒXƒ} ƒEƒCƒWƒƒƒ„ƒTƒXƒgƒ‰ kn-aut-sei=ƒNƒXƒ} ƒEƒCƒWƒƒƒ„ kn-aut-mei=ƒTƒXƒgƒ‰ aut-affil-num=1 ORCID= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=‰ª‹v—Y kn-aut-sei=‰ª kn-aut-mei=‹v—Y aut-affil-num=2 ORCID= en-aut-name=SarataniKeiji en-aut-sei=Saratani en-aut-mei=Keiji kn-aut-name=X’JŒ[Ž¡ kn-aut-sei=X’J kn-aut-mei=Œ[Ž¡ aut-affil-num=3 ORCID= en-aut-name=MatsutaniYoshio en-aut-sei=Matsutani en-aut-mei=Yoshio kn-aut-name=¼’J‘P—Y kn-aut-sei=¼’J kn-aut-mei=‘P—Y aut-affil-num=4 ORCID= en-aut-name=TatsutaMitsuhiro en-aut-sei=Tatsuta en-aut-mei=Mitsuhiro kn-aut-name=—´“cŒõO kn-aut-sei=—´“c kn-aut-mei=ŒõO aut-affil-num=5 ORCID= en-aut-name=KawazoeTakayoshi en-aut-sei=Kawazoe en-aut-mei=Takayoshi kn-aut-name=ì“Yꟕj kn-aut-sei=ì“Y kn-aut-mei=ꟕj aut-affil-num=6 ORCID= en-aut-name=KojimaHideki en-aut-sei=Kojima en-aut-mei=Hideki kn-aut-name=¬“ˆ‰pŠ² kn-aut-sei=¬“ˆ kn-aut-mei=‰pŠ² aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@Ž©‘R‰ÈŠwŒ¤‹†‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰ÈŒŸ¸‹Zp‰ÈŠwêU affil-num=3 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ affil-num=4 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ affil-num=5 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ affil-num=6 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ affil-num=7 en-affil= kn-affil=—²ËŽY‹ÆŠ”Ž®‰ïŽÐ¶ŽY–{•”‹Zp•” en-keyword=Tooth mobility (Ž•‚Ì“®—h) kn-keyword=Tooth mobility (Ž•‚Ì“®—h) en-keyword=mechanical mobility (‹@ŠBƒ‚ƒrƒŠƒeƒB) kn-keyword=mechanical mobility (‹@ŠBƒ‚ƒrƒŠƒeƒB) en-keyword=dental implant (ƒCƒ“ƒvƒ‰ƒ“ƒg) kn-keyword=dental implant (ƒCƒ“ƒvƒ‰ƒ“ƒg) en-keyword=manual examination (Gf) kn-keyword=manual examination (Gf) END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=2 article-no= start-page=101 end-page=106 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=‰Á‰·Œã‚ÌtsAF8×–E‚Ì×–EŽüŠú kn-title=Cell cycle of tsAF8 after heating en-subtitle= kn-subtitle= en-abstract=tsAF8×–E‚Í45Ž‚̉Á‰·Œã34Ž‚Å”|—{‚·‚é‚Ɖ·”M‘Ï«‚ª‘¬‚â‚©‚É”­Œ»‚·‚邪,‰Á‰·Œã,§ŒÀ‰·“x‚Å‚ ‚é39.7Ž‚Å”|—{‚·‚é‚Ɖ·”M‘Ï«‚Ì”­Œ»‚ª—}§‚³‚ê‚顉Á‰·Œã‚Ì”|—{‰·“x‚ª×–EŽüŠú‚ɉe‹¿‚µ,‚»‚ÌŒ‹‰Ê‚Æ‚µ‚ĉ·”M‘Ï«”­Œ»‚ɉe‹¿‚ð—^‚¦‚Ä‚¢‚é‰Â”\«‚ª‚ ‚邱‚Æ‚©‚ç,¡‰ñ,Propidium Iodide(PI)‚Æbromodeoxyuridine(BrdU)‚ÅtsAF8×–E‚ð“ñdõF‚µ,ƒtƒ[ƒTƒCƒgƒƒgƒŠ[‚É‚æ‚Á‚ĉ·”M‘Ï«‚Æ×–EŽüŠú‚ÌŠÖŒW‚Ì—L–³‚ɂ‚¢‚Ä’²‚ׂ½¡tsAF8×–E‚ð45Ž20•ª‚̉Á‰·Œã34Ž‚Å”|—{‚·‚é‚Æ,6ŽžŠÔŒã‚É‚ÍG(1)Šú‚Ì×–E‚ªŒ¸­‚µ,12ŽžŠÔŒã‚É‚ÍG(2)/MŠú‚Ö‚Ì’~Ï‚ªŒ©‚ç‚ꂽ¡‚µ‚©‚µ,‰Á‰·Œã39.7Ž‚Å”|—{‚µ‚½ê‡‚É‚Í×–EŽüŠú‚Ìis‚ª‚Ù‚Æ‚ñ‚ÇŒ©‚ç‚ê‚È‚©‚Á‚½¡BrdU ‚ÌŽæž‚Ý‚Í,‰Á‰·‚¹‚¸‚É39.7Ž‚Å”|—{‚µ‚½ê‡‚É‚ÍŠˆ”­‚És‚í‚ê,‚Ü‚½,45Ž20•ª‰Á‰·Œã34Ž‚Å”|—{‚µ‚½ê‡‚É‚Í,6ŽžŠÔŒã‚É‚ÍBrdU‚ÌŽæ‚èž‚Ý‚Í65.1%‚܂ʼnñ•œ‚µ‚½¡‚µ‚©‚µ,‰·”M‘Ï«”­Œ»‚Ì—}§‚ªŠÏŽ@‚³‚ê‚é45Ž20•ª‰Á‰·Œã39.7Ž‚Å”|—{‚µ‚½ê‡‚É‚Í,BrdU‚ÌŽæž‚Ý—Ê‚Í6ŽžŠÔŒã‚Ɉꎞ“I‚É15.1%‚ɉñ•œ‚·‚邪,12ŽžŠÔŒã‚ɂ͎枂ݗʂ̓[ƒ‚Æ‚È‚Á‚½¡BrdU‚ÌŽæ‚èž‚Ý‚ª‘jŠQ‚³‚ꂽ‚Ì‚Ístep-down heating‚ÌŒ»Û‚É‚æ‚é×–E¶‘¶—¦‚ÌŒ¸­‚ªŒ´ˆö‚¾‚Æl‚¦‚ç‚ꂽ‚ª,‰·”M‘Ï«”­Œ»‚Ì—}§‚ªŠÏŽ@‚³‚ê‚éðŒ‰º‚Å‚Í×–EŽüŠú‚Ì“Á’è‚ÌŽžŠú‚Ö‚ÌWÏ‚ª‚È‚©‚Á‚½‚±‚Æ‚©‚ç,‰·”M‘Ï«‚Æ×–EŽüŠú‚Æ‚ÌŠÖŒW‚ÍtsAF8×–E‚É‚¨‚¢‚Ä‚ÍŒ©‚¢o‚³‚ê‚È‚©‚Á‚½¡ kn-abstract=Thermotolerance in tsAF8 cells develops during incubation at 34Ž after heating at 45Ž, while it is suppressed by the following incubation at a non-permissive temperature of 39.7Ž after the same heating. The incubation temperature after heating may affect the cell cycle and consequently thermotolerance. In the present study, a relationship between the thermotolerance and the cell cycle of tsAF8 was investigated. The cell cycle fractions and DNA synthesis were measured by flow cytometry using double staining with propidium iodide and bromodeoxyuridine. When the tsAF8 cells were heated at 45Ž for 20 min, and thereafter incubated at 34Ž, bromodeoxyuridine uptake in the S phase cells (DNA synthesis) was recovered to 65.1% 6 h after the heating, and the cells showed gradual accumulation in the G(2)/M phase. When the cells were incubated at 39.7Ž after heating at 45Ž for 20 min, then showed inhibition of thermotolerance development, the DNA synthesis was recovered to 15.1% temporarily 6 h after the heating, but it became 0% after 12 h, and the cells did not remarkably accumulate in any phases of the cell cycle. This inhibition of DNA synthesis at 39.7Ž was considered to be the result of cell survival decreasing by a step-down heating. However, the relationship between the thermotolerance and the cell cycle was not found out in tsAF8 cells, because the cells did not accumulate in any phases of the cell cycle under the inhibitory condition of thermotolerance. en-copyright= kn-copyright= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=àF’JŒõˆê kn-aut-sei=àF’J kn-aut-mei=Œõˆê aut-affil-num=1 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=ìèË“ñ kn-aut-sei=ìè kn-aut-mei=Ë“ñ aut-affil-num=2 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=•“c¹G kn-aut-sei=•“c kn-aut-mei=¹G aut-affil-num=3 ORCID= en-aut-name=AsaumiJun-ichi en-aut-sei=Asaumi en-aut-mei=Jun-ichi kn-aut-name=óŠC~ˆê kn-aut-sei=óŠC kn-aut-mei=~ˆê aut-affil-num=4 ORCID= en-aut-name=KatoHirokazu en-aut-sei=Kato en-aut-mei=Hirokazu kn-aut-name=‰Á“¡”Ž˜a kn-aut-sei=‰Á“¡ kn-aut-mei=”Ž˜a aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰È•úŽËü‹Zp‰ÈŠwêU affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰È•úŽËü‹Zp‰ÈŠwêU affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@•úŽËü‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰È•úŽËü‹Zp‰ÈŠwêU affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@•úŽËü‰È en-keyword=thermotolerance (‰·”M‘Ï«) kn-keyword=thermotolerance (‰·”M‘Ï«) en-keyword=hyperthermia (ƒnƒCƒp[ƒT[ƒ~ƒA) kn-keyword=hyperthermia (ƒnƒCƒp[ƒT[ƒ~ƒA) en-keyword=tsAF8 kn-keyword=tsAF8 en-keyword=cell cycle (×–EŽüŠú) kn-keyword=cell cycle (×–EŽüŠú) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=9 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20041215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol in the rat kn-title=‚Í‚Æ‚Þ‚¬,‚Í‚Æ‚Þ‚¬ƒeƒ“ƒy‚̃‰ƒbƒgƒRƒŒƒXƒeƒ[ƒ‹‘ãŽÓ‰ü‘Pì—p‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract=The effect of Coicis semen and Rhizopus oligosporus-fermented Coicis semen (tempeh) on serum cholesterol fractions was examined in the rat. Twelve-week-old male Sprague-Dawley rats were received commercial MF meal (control group), Coicis semen-containing MF meal (Coicis semen group), or tempeh-containing MF meal (tempeh group). Cholesterol fractions were analyzed by high performance liquid chromatography at the start of experiment, and 2, 6, 18 weeks later. No difference was found in body weight nor total cholesterol among the three groups. LDL cholesterol was significantly lowered in the tempeh group at 2, 6, 18 weeks. LDL cholesterol/HDL cholesterol ratio also decreased at 2 and 18 weeks. In the both Coicis semen- and tempeh-fooded groups, LDL cholesterol and LDL cholesterol/HDL cholesterol ratio were lower than the control group although they were not statistically significant. No difference was found in HDL cholesterol among the three groups. The results suggest that tempeh may have a favorable effect on cholesterol metabolism. kn-abstract=‚Í‚Æ‚Þ‚¬(Coicis semen)‚ðƒeƒ“ƒy‹Û(Rhizopus oligosporus)‚Å”­y‚µ‚½‚Í‚Æ‚Þ‚¬ƒeƒ“ƒy(ƒeƒ“ƒy)‚ÌŒŒ´ƒRƒŒƒXƒeƒ[ƒ‹‘ãŽÓ‚ɑ΂·‚éì—p‚ðŒŸ“¢‚µ‚½¡¶Œã12T—î‚ÌSprague-DawleyŒn—Yƒ‰ƒbƒg‚ÉŽs”̌Ō`Ž”—¿(ƒRƒ“ƒgƒ[ƒ‹ŒQ),‚Í‚Æ‚Þ‚¬¬‡Ž”—¿(‚Í‚Æ‚Þ‚¬ŒQ),ƒeƒ“ƒy¬‡Ž”—¿(ƒeƒ“ƒyŒQ)‚ð“Š—^‚µ,2,6,18TŠÔŒã‚É‚‘¬‰t‘̃Nƒƒ}ƒgƒOƒ‰ƒtƒB[–@‚ÅŒŒ´ƒRƒŒƒXƒeƒ[ƒ‹‚𑪒肵‚½¡‘Ìd‘‰Á,‘ƒRƒŒƒXƒeƒ[ƒ‹‚Í‚¢‚¸‚ê‚ÌŽž“_‚Å‚à3ŒQŠÔ‚É·‚ª‚È‚©‚Á‚½‚ª,ƒeƒ“ƒyŒQ‚Å‚Í“Š—^‘O‚Æ”äŠr‚µ‚Ä2,6,18TŠÔŒã‚ÉLDLƒRƒŒƒXƒeƒ[ƒ‹‚ª—LˆÓ‚ɒቺ‚µ,LDLƒRƒŒƒXƒeƒ[ƒ‹/HDLƒRƒŒƒXƒeƒ[ƒ‹”ä‚à2,18TŠÔŒã‚É—LˆÓ‚ɒቺ‚µ‚½¡ƒeƒ“ƒyŒQ‚̓Rƒ“ƒgƒ[ƒ‹ŒQ‚Æ”äŠr‚µ‚Ä‚àLDLƒRƒŒƒXƒeƒ[ƒ‹‚ÆLDLƒRƒŒƒXƒeƒ[ƒ‹/HDLƒRƒŒƒXƒeƒ[ƒ‹”䂪’á‚­,‚Í‚Æ‚Þ‚¬ŒQ‚Å‚à’á‚¢ŒXŒü‚ª‚Ý‚ç‚ꂽ‚ª,—LˆÓ·‚Í‚È‚©‚Á‚½¡ˆÈã‚©‚ç,ƒeƒ“ƒy‚ªƒRƒŒƒXƒeƒ[ƒ‹‘ãŽÓ‰ü‘Pì—p‚ð‚à‚‚±‚Æ‚ªŽ¦´‚³‚ꂽ¡ en-copyright= kn-copyright= en-aut-name=OkamotoMotoi en-aut-sei=Okamoto en-aut-mei=Motoi kn-aut-name=‰ª–{Šî kn-aut-sei=‰ª–{ kn-aut-mei=Šî aut-affil-num=1 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name=‰Pˆä^ˆê kn-aut-sei=‰Pˆä kn-aut-mei=^ˆê aut-affil-num=2 ORCID= en-aut-name=OkazakiMitsuyo en-aut-sei=Okazaki en-aut-mei=Mitsuyo kn-aut-name=‰ªèŽO‘ã kn-aut-sei=‰ªè kn-aut-mei=ŽO‘ã aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰ÈŒŸ¸‹Zp‰ÈŠwêU affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰ÈŒŸ¸‹Zp‰ÈŠwêU affil-num=3 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠw‹³—{•” en-keyword=‚Í‚Æ‚Þ‚¬ (Coicis semen) kn-keyword=‚Í‚Æ‚Þ‚¬ (Coicis semen) en-keyword=‚Í‚Æ‚Þ‚¬ƒeƒ“ƒy (Rhizopus oligosporus, tempeh) kn-keyword=‚Í‚Æ‚Þ‚¬ƒeƒ“ƒy (Rhizopus oligosporus, tempeh) en-keyword=ƒRƒŒƒXƒeƒ[ƒ‹ (cholesterol) kn-keyword=ƒRƒŒƒXƒeƒ[ƒ‹ (cholesterol) en-keyword=ƒ‰ƒbƒg (rat) kn-keyword=ƒ‰ƒbƒg (rat) END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=1 article-no= start-page=35 end-page=40 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Supporting female physicians in career development : Activity report on MEXT-supported projects and our future plans kn-title=—«ˆãŽt‚̃LƒƒƒŠƒAŽx‰‡@‚g19•¶•”‰ÈŠwȎЉï“Iƒj[ƒY‚ɑΉž‚µ‚½Ž¿‚Ì‚‚¢ˆã—Ãl—{¬„iƒvƒƒOƒ‰ƒ€iˆã—Ãl GPj‘I’è@u—«‚𶂩‚·ƒLƒƒƒŠƒAŽx‰‡Œv‰æv‚ÌŠˆ“®•ñ‚Æ¡Œã en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KataokaHitomi en-aut-sei=Kataoka en-aut-mei=Hitomi kn-aut-name=•Ð‰ªm”ü kn-aut-sei=•Ð‰ª kn-aut-mei=m”ü aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”EŽ•Šw•”•a‰@@‘²Œã—Õ°Œ¤CƒZƒ“ƒ^[CƒLƒƒƒŠƒAƒZƒ“ƒ^[iˆã—Ãl GP Ž––±‹Çj en-keyword=—«ˆãŽt kn-keyword=—«ˆãŽt en-keyword=ƒLƒƒƒŠƒA kn-keyword=ƒLƒƒƒŠƒA en-keyword=•œEŽx‰‡ kn-keyword=•œEŽx‰‡ en-keyword=ƒVƒ~ƒ…ƒŒ[ƒVƒ‡ƒ“ƒgƒŒ[ƒjƒ“ƒO kn-keyword=ƒVƒ~ƒ…ƒŒ[ƒVƒ‡ƒ“ƒgƒŒ[ƒjƒ“ƒO en-keyword=‰®ªŠ¢Ž®ƒTƒ|[ƒg kn-keyword=‰®ªŠ¢Ž®ƒTƒ|[ƒg END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=4-5 article-no= start-page=513 end-page=519 dt-received= dt-revised= dt-accepted= dt-pub-year=1966 dt-pub=19660530 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=—®‹…‹{ŒÃŒQ“‡‚É‚¨‚¯‚鬒†ŠwZŠw“¶‚̈ãŠw“I’²¸‚ɂ‚¢‚Ä en-subtitle= kn-subtitle= en-abstract= kn-abstract=An expedition was performed on Miyako Is., Ryukyu, carrying out medical examinations on school-children in May and June, 1965. The investigations consisted of screening tests for acatalasemic gene carriers and ENT examinations. Results obtained are as follows: 1. ENT examinations; morbidity to ear diseases of Miyako children was higher than that of Japan proper. On the contrary morbidity to nose and throat diseases of Miyako was lower than Japan Proper. 2. Screening tests; only one hypocatalasemic boy was found out among 10, 083 children examined. Then emergence of hypocatalasemia on Miyako Is. was 0.01%, one tenth of already known Japanese mean value. en-copyright= kn-copyright= en-aut-name=OguraYoshio en-aut-sei=Ogura en-aut-mei=Yoshio kn-aut-name=¬‘q‹`˜Y kn-aut-sei=¬‘q kn-aut-mei=‹`˜Y aut-affil-num=1 ORCID= en-aut-name=KoyamaTakashi en-aut-sei=Koyama en-aut-mei=Takashi kn-aut-name=¬ŽR‚Ži kn-aut-sei=¬ŽR kn-aut-mei=‚Ži aut-affil-num=2 ORCID= en-aut-name=HoriFumio en-aut-sei=Hori en-aut-mei=Fumio kn-aut-name=–x“T—Y kn-aut-sei=–x kn-aut-mei=“T—Y aut-affil-num=3 ORCID= en-aut-name=SumidaShozo en-aut-sei=Sumida en-aut-mei=Shozo kn-aut-name=Z“cºŽO kn-aut-sei=Z“c kn-aut-mei=ºŽO aut-affil-num=4 ORCID= en-aut-name=MitaniYasuo en-aut-sei=Mitani en-aut-mei=Yasuo kn-aut-name=ŽO’J‹±•v kn-aut-sei=ŽO’J kn-aut-mei=‹±•v aut-affil-num=5 ORCID= en-aut-name=KurodaYasuo en-aut-sei=Kuroda en-aut-mei=Yasuo kn-aut-name=•“c‘׶ kn-aut-sei=•“c kn-aut-mei=‘׶ aut-affil-num=6 ORCID= en-aut-name=OhkuraKoji en-aut-sei=Ohkura en-aut-mei=Koji kn-aut-name=‘å‘q‹»Ži kn-aut-sei=‘å‘q kn-aut-mei=‹»Ži aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”Ž¨•@ˆôA‰ÈŠw‹³Žº affil-num=7 en-affil= kn-affil=“Œ‹žˆã‰ÈŽ•‰È‘åŠwl—Þˆâ“`ŠwŒ¤‹†Žº END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=447 end-page=454 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Free radicals, superoxide dismutase activity and lipid peroxides in gingiva of ODU plaque-susceptible rats kn-title=Ž•“÷‰ŠŽ©‘R”­Çƒ‰ƒbƒg‚ÌŽ•“÷‰Š”­Ç‚É‚¨‚¯‚éƒtƒŠ[ƒ‰ƒWƒJƒ‹‚ÌŠÖ—^‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Free radicals, superoxide dismutase activity and lipid peroxides in the gingiva of Dental University (ODU) plaque-susceptible (Sus) rats were estimated at the ages of 1,2,3,4,5,7 and 8 months, and were compared with those of control Wistar-kyoto rats. Low levels of hydroxyl radicals were noted in the anterior and posterior gingiva of ODU Sus rats at 2 and 5 month, but significantly increased in the anterior gingiva at 4 and 7 months and in the anterior and posterior gingiva at 7 and 8 months, compared to those of control rats. Levels of carbon centered radicals were significantly higher in the anterior gingiva at 2 months and in both the anterior and posterior gingiva at 3 months. Superoxide dismutase activities were accelerated significantly at 2,4 and 5 months, and then were reduced at 8 months in the anterior gingiva. Otherwise, they were at low levels in the posterior gingiva at 1 and 2 months, were accelerated at 3 and 4 months, and reduced again at 7 and 8 months. Thiobarbituric acid reactive substances decreased transitorily at 7 months in both the anterior and posterior. These experimental results suggest that free radicals may be related to the pathogenesis and development of gingivitis in plaque susceptible ODU Sus rats. en-copyright= kn-copyright= en-aut-name=SatohKazuyoshi en-aut-sei=Satoh en-aut-mei=Kazuyoshi kn-aut-name=²“¡˜a—Ç kn-aut-sei=²“¡ kn-aut-mei=˜a—Ç aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•ªŽq×–EˆãŠwŒ¤‹†Ž{Ý_Œoî•ñŠw•”–å en-keyword=Ž•“÷‰ŠŽ©‘R”­Çƒ‰ƒbƒg kn-keyword=Ž•“÷‰ŠŽ©‘R”­Çƒ‰ƒbƒg en-keyword=ƒtƒŠ[ƒ‰ƒWƒJƒ‹ kn-keyword=ƒtƒŠ[ƒ‰ƒWƒJƒ‹ en-keyword=Šˆ«Ž_‘f kn-keyword=Šˆ«Ž_‘f en-keyword=‰ßŽ_‰»Ž‰Ž¿ kn-keyword=‰ßŽ_‰»Ž‰Ž¿ en-keyword=ƒX[ƒp[ƒIƒLƒVƒhƒWƒ€ƒXƒ^[ƒ[Šˆ« kn-keyword=ƒX[ƒp[ƒIƒLƒVƒhƒWƒ€ƒXƒ^[ƒ[Šˆ« END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue=3 article-no= start-page=299 end-page=305 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20081201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The collaborative role of oral surgery with plastic as well as head & neck surgery in head and neck cancers : Preoperative plate-bending method in cases with mandibular reconstruction using plaster 3D models kn-title=“ªèò•”Šà‚É‚¨‚¯‚铪èò•”ŠO‰ÈCŒ`¬ŠO‰ÈCŒûoŠO‰È‚R‰È‡“¯Žèp‚É‚¨‚¯‚éŒûoŠO‰È‚Ì–ðŠ„F‰ºŠ{ÄŒšÇ—á‚É‚¨‚¯‚é‚R‚cÎp‘¢Œ`ƒ‚ƒfƒ‹‚ð—˜—p‚µ‚½p‘OƒvƒŒ[ƒg‹ü‹È–@ en-subtitle= kn-subtitle= en-abstract= kn-abstract=The collaboration of various medical teams is crucial for the appropriate treatment of cancer patients. However, in Japan, it is very difficult for oral surgeons to cooperate with head and neck surgeons due to conflicts in the treatment of those patients. There have been few studies on this subject. In the current work, we report on the collaboration of head and neck surgeons, plastic surgeons and oral surgeons in operations on two patients with gingival carcinomas in the mandible. We first prepared plaster 3D models of the patients'mouths by means of ink-jet from CT data. We pre-bent the reconstruction plates using the preoperative 3D models. Therefore, we could save the time required to bend the plate. Plaster models are cheaper than resin models. It is also easy to model the surgery using the plate. During the operation, head and neck surgeons resected the tumors, plastic surgeons performed reconstruction with vascularized bone or skin graft, and oral surgeons (dentists) did plate fixation and took charge of the patients'occlusion. This method resulted in patients having good occlusion after the operation. en-copyright= kn-copyright= en-aut-name=MizukawaNobuyoshi en-aut-sei=Mizukawa en-aut-mei=Nobuyoshi kn-aut-name=…ì“W‹g kn-aut-sei=…ì kn-aut-mei=“W‹g aut-affil-num=1 ORCID= en-aut-name=TominagaSusumu en-aut-sei=Tominaga en-aut-mei=Susumu kn-aut-name=•y‰ii kn-aut-sei=•y‰i kn-aut-mei=i aut-affil-num=2 ORCID= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=–،Ҍh—T kn-aut-sei=–ØŒÒ kn-aut-mei=Œh—T aut-affil-num=3 ORCID= en-aut-name=OnodaTomoo en-aut-sei=Onoda en-aut-mei=Tomoo kn-aut-name=¬–ì“c—F’j kn-aut-sei=¬–ì“c kn-aut-mei=—F’j aut-affil-num=4 ORCID= en-aut-name=SugiyamaNarushi en-aut-sei=Sugiyama en-aut-mei=Narushi kn-aut-name=™ŽR¬Žj kn-aut-sei=™ŽR kn-aut-mei=¬Žj aut-affil-num=5 ORCID= en-aut-name=YamachikaEiki en-aut-sei=Yamachika en-aut-mei=Eiki kn-aut-name=ŽR‹ß‰pŽ÷ kn-aut-sei=ŽR‹ß kn-aut-mei=‰pŽ÷ aut-affil-num=6 ORCID= en-aut-name=YamadaYousuke en-aut-sei=Yamada en-aut-mei=Yousuke kn-aut-name=ŽR“c—f‰î kn-aut-sei=ŽR“c kn-aut-mei=—f‰î aut-affil-num=7 ORCID= en-aut-name=KimuraTakuji en-aut-sei=Kimura en-aut-mei=Takuji kn-aut-name=–Ø‘º‘쎢 kn-aut-sei=–Ø‘º kn-aut-mei=‘쎢 aut-affil-num=8 ORCID= en-aut-name=TakeuchiTetsuo en-aut-sei=Takeuchi en-aut-mei=Tetsuo kn-aut-name=’|“à“N’j kn-aut-sei=’|“à kn-aut-mei=“N’j aut-affil-num=9 ORCID= en-aut-name=UenoTakaaki en-aut-sei=Ueno en-aut-mei=Takaaki kn-aut-name=A–ì‚Í kn-aut-sei=A–ì kn-aut-mei=‚Í aut-affil-num=10 ORCID= en-aut-name=TakagiShin en-aut-sei=Takagi en-aut-mei=Shin kn-aut-name=‚–ØT kn-aut-sei=‚–Ø kn-aut-mei=T aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”EŽ•Šw•”•‘®•a‰@@ŒûoŠO‰ÈÄŒšŒn affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Ž¨•@ˆôAE“ªèò•”ŠO‰ÈŠw affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Œ`¬ÄŒšŠO‰ÈŠw affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Ž¨•@ˆôAE“ªèò•”ŠO‰ÈŠw affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Œ`¬ÄŒšŠO‰ÈŠw affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Š{ŒûoÄŒšŠO‰ÈŠw affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”EŽ•Šw•”•‘®•a‰@@ŒûoŠO‰È•a‘ÔŒn affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”EŽ•Šw•”•‘®•a‰@@ŒûoŠO‰È•a‘ÔŒn affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”EŽ•Šw•”•‘®•a‰@@ˆã—ËZp•”Ž•‰ÈŒn•”–å‹ZHŽº affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Š{ŒûoÄŒšŠO‰ÈŠw affil-num=11 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È@Š{ŒûoÄŒšŠO‰ÈŠw en-keyword=ƒ`[ƒ€ˆã—à (medical team approach) kn-keyword=ƒ`[ƒ€ˆã—à (medical team approach) en-keyword=“ªèò•”Šà (head and neck carcinoma) kn-keyword=“ªèò•”Šà (head and neck carcinoma) en-keyword=‚R‚cÎpƒ‚ƒfƒ‹ (plaster 3D model) kn-keyword=‚R‚cÎpƒ‚ƒfƒ‹ (plaster 3D model) en-keyword=ƒCƒ“ƒNƒWƒFƒbƒg–@ (ink-jet method) kn-keyword=ƒCƒ“ƒNƒWƒFƒbƒg–@ (ink-jet method) en-keyword=‰ºŠ{ÄŒš (mandibular reconstruction) kn-keyword=‰ºŠ{ÄŒš (mandibular reconstruction) END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=51 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Cross-sectional study of dietary habits and dental caries among senior high school students kn-title=‚Z¶‚É‚¨‚¯‚éHKŠµ‚ÆêšI”­¶‚É‚¨‚¯‚鉡’f“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three hundred fifty-nine senior high school students were examined for dental caries and dietary habits and the findings were subjected to mono- and multivariate analyses. Dental caries were higher in female students and differed between the anterior teeth and molars. In female students, frequently eating potatoes and having increased dental caries showed a significantly higher odds ratio. On multivariate analysis, a mixed group of male and female students showed high odds ratios for bread, fruit and dairy products. These results indicate that modernization of dietary habits is closely associated with dental caries in adults. en-copyright= kn-copyright= en-aut-name=TakaharaMasahiko en-aut-sei=Takahara en-aut-mei=Masahiko kn-aut-name=ûüŒ´‰ë•F kn-aut-sei=ûüŒ´ kn-aut-mei=‰ë•F aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”‰q¶Šw‹³Žº en-keyword=êšI kn-keyword=êšI en-keyword=HKŠµ kn-keyword=HKŠµ en-keyword=‰¡’fŒ¤‹† kn-keyword=‰¡’fŒ¤‹† en-keyword=‘½•Ï—ʉðÍ kn-keyword=‘½•Ï—ʉðÍ END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=3-8 article-no= start-page=47 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study on factors relating to oral malodor and preventive measures among the elderly kn-title=—v‰îŒì‚—îŽÒ‚É‚¨‚¯‚éŒûL‚Æ‚»‚ÌŠÖ˜A—vˆö‹y‚Ñ—\–h‘Îô‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract=One hundred ten elderly with disabilities in institutions or receiving home care were selected and informed. This study focused on oral malodor and discusses consent was obtained the relationship between oral malodor and the state of dental health and oral hygiene in the elderly with disabilities. ADL of the elderly with disabilities (rank J, A, B, C, settled by National Health Administration in Japan) were 8.2% at rank J, 28.2% at rank A, 42.7% at rank B and 20.9% at rank C, respectively. The incident rate of swallowing pneumonitis, fever and bedsores were low. Accordingly, physical and mental conditions were comparatively preferable. Tooth and periodontal conditions were comparablye to nationwide results. 1. The elderly in poor ADL had marked oral malodor compared with those in good health. 2. The elderly who required assistance to eat or had special dietary requirements had marked oral malodor. 3. The elderly who had normal oral functions and the ability to take care of their own oral hygiene had markedly less oral malodor. 4. The elderly who had poor oral hygiene exhibitings thick tongue coating and positive results in a Candida albicans culture test, had marked oral malodor. 5. Using, the multivariate statistical analysis of Hayashi methods‡U, the coefficient of correlation between the state of oral malodor and 27 variables was obtained. 1) The study obtained trustworthy values that discriminate analysis 92.7% and correlation ratio is 0.53. 2) The variables related to severe oral malodor, extracted by the multivariate statistical analysis in descending order, were: "low level of ADL in gargling and denture brushing", "cigarette smoking", "speech disabilities", "unsatisfactory mastication", "need for special dietary care", "oral druyness", "gingivitis", "soft diet of side dish", "living in a special institution caring for the elderly", "thick tongue coating", and "a positive Candida albicans culture test", respectively. 3) The items related with comparatively comfortable or bearable oral malodor, extracted by the multivariate statistical analysis in descending order were : "satisfactory mastication", "home care", "healthy or poor eyesight", "difficulty in mastication", "being able to independently remove, dentures", "a negative Candida albicans culture test", "no oral dryness", "independents in selecting diet", "comfortable gingival condition", "being dependent on others for tooth-brushing" and "preferable tongue coating", respectively. 4) For the effective preventive countermeasures of oral malodor, ADL of oral health, caring circumstances and hygiene of gingiva/tongue should be focused on rather than dental hygiene itself. en-copyright= kn-copyright= en-aut-name=EgusaMasahiko en-aut-sei=Egusa en-aut-mei=Masahiko kn-aut-name=]‘³•F kn-aut-sei=]‘ kn-aut-mei=³•F aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”‰q¶ŠwuÀ en-keyword=Elederly with disabilities kn-keyword=Elederly with disabilities en-keyword=Oral malodor kn-keyword=Oral malodor en-keyword=Preventive countermeasure kn-keyword=Preventive countermeasure en-keyword=Related factor kn-keyword=Related factor en-keyword=Multivariate statistical analysis kn-keyword=Multivariate statistical analysis END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=2 article-no= start-page=141 end-page=146 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Accidents in dental treatment: A questionnaire investigation kn-title=Ž•‰ÈˆãŽt‚ÌA‹Æ󋵂Æf—Ëô”­Ž–ŒÌ en-subtitle= kn-subtitle= en-abstract= kn-abstract=The relationship between the operational situation of dental treatment and accidents experienced was investigated through questionnaires sent to members of the Kagawa Dental Association. Responses were received from 261 dentists (53% response rate), of whom 113 (43%) had experienced accidents during dental examinations and/or treatment during the past one year. Dentists with a particularly high risk of having accidents were predominantly young males who possessed many medical chairs at their clinic and who daily examined many patients. Those dentists who worked together with two or more colleagues had a lower risk of accidents. These factors should be considered when trying to take preventive measures against accidents during medical examinations and treatment. en-copyright= kn-copyright= en-aut-name=OnoHiroshi en-aut-sei=Ono en-aut-mei=Hiroshi kn-aut-name=¬–ìœA kn-aut-sei=¬–ì kn-aut-mei=œA aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”ˆãŠw‰È en-keyword=Ž•‰Èf—à (dental treatment) kn-keyword=Ž•‰Èf—à (dental treatment) en-keyword=‹ô”­Ž–ŒÌ (accident) kn-keyword=‹ô”­Ž–ŒÌ (accident) en-keyword=Ž¿–⎆’²¸ (questionnaires) kn-keyword=Ž¿–⎆’²¸ (questionnaires) END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=2 article-no= start-page=113 end-page=117 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Accumulating DNA methylation in background mucosa plays a role in esophageal squamous cell carcinogenesis kn-title=H“¹G•½ã”çŠà‚Ì”­Šà‰ß’ö‚É‚¨‚¯‚éDNAƒƒ`ƒ‹‰»‚Ì–ðŠ„ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshiiTatsuhiro en-aut-sei=Ishii en-aut-mei=Tatsuhiro kn-aut-name=Έ䗴G kn-aut-sei=Έä kn-aut-mei=—´G aut-affil-num=1 ORCID= en-aut-name=MurakamiJun en-aut-sei=Murakami en-aut-mei=Jun kn-aut-name=‘ºãƒ kn-aut-sei=‘ºã kn-aut-mei=ƒ aut-affil-num=2 ORCID= en-aut-name=NotoharaKenji en-aut-sei=Notohara en-aut-mei=Kenji kn-aut-name=”\“oŒ´Œ›Ži kn-aut-sei=”\“oŒ´ kn-aut-mei=Œ›Ži aut-affil-num=3 ORCID= en-aut-name=SasamotoHiromi en-aut-sei=Sasamoto en-aut-mei=Hiromi kn-aut-name=ù–{”Ž”ü kn-aut-sei=ù–{ kn-aut-mei=”Ž”ü aut-affil-num=4 ORCID= en-aut-name=KambaraTakeshi en-aut-sei=Kambara en-aut-mei=Takeshi kn-aut-name=_Œ´Œ’ kn-aut-sei=_Œ´ kn-aut-mei=Œ’ aut-affil-num=5 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=”’ì–õ”Ž kn-aut-sei=”’ì kn-aut-mei=–õ”Ž aut-affil-num=6 ORCID= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=—P–{—Ç•v kn-aut-sei=—P–{ kn-aut-mei=—Ç•v aut-affil-num=7 ORCID= en-aut-name=OuchidaMamoru en-aut-sei=Ouchida en-aut-mei=Mamoru kn-aut-name=‘å“à“cŽç kn-aut-sei=‘å“à“c kn-aut-mei=Žç aut-affil-num=8 ORCID= en-aut-name=ShimizuKenji en-aut-sei=Shimizu en-aut-mei=Kenji kn-aut-name=´…Œ›“ñ kn-aut-sei=´… kn-aut-mei=Œ›“ñ aut-affil-num=9 ORCID= en-aut-name=JeremyR. Jass en-aut-sei=Jeremy en-aut-mei=R. Jass kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=MatsubaraNagahide en-aut-sei=Matsubara en-aut-mei=Nagahide kn-aut-name=¼Œ´’·G kn-aut-sei=¼Œ´ kn-aut-mei=’·G aut-affil-num=11 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=“c’†‹IÍ kn-aut-sei=“c’† kn-aut-mei=‹IÍ aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Ž•‰ÈŒûo•úŽËüŠw affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È •a‘Ô’T‹†ˆãŠw affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È •ªŽqˆâ“`Šw affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È •ªŽqˆâ“`Šw affil-num=10 en-affil= kn-affil=Department of Pathology, McGill University affil-num=11 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw affil-num=12 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@ˆãŽ•–òŠw‘‡Œ¤‹†‰È Á‰»ŠíEŽîᇊO‰ÈŠw en-keyword=H“¹G•½ã”çŠà kn-keyword=H“¹G•½ã”çŠà en-keyword=ƒvƒƒ‚[ƒ^[ƒƒ`ƒ‹‰» kn-keyword=ƒvƒƒ‚[ƒ^[ƒƒ`ƒ‹‰» en-keyword=p53ˆâ“`Žq•ÏˆÙ kn-keyword=p53ˆâ“`Žq•ÏˆÙ END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=¬Ž™‚ÌŽ•‰È‹°•|‚ÉŠÖ‚·‚錤‹†-•ÛŒìŽÒ‰ñ“š—p“ú–{Œê”ÅCFSS-DS‚Ì—L—p«‚Æ’á”N—‚ÌŽ•‰È‹°•|‚ÌŽÀ‘Ô- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MoriYukako en-aut-sei=Mori en-aut-mei=Yukako kn-aut-name=X—T‰ÀŽq kn-aut-sei=X kn-aut-mei=—T‰ÀŽq aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ƒ~ƒjƒXƒNƒŠƒ…[‚ðŒÅ’茹‚É—p‚¢‚½‹¸³Ž•‰ÈŽ¡—Â̗հ“IŒŸ“¢]¬Œ÷—¦‹y‚ÑŽ¡—ÃŒø‰Ê‚Ì”äŠr] en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamadaKazuyo en-aut-sei=Yamada en-aut-mei=Kazuyo kn-aut-name=ŽR“c˜a‘ã kn-aut-sei=ŽR“c kn-aut-mei=˜a‘ã aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ŒûoƒPƒAE‰îŒìŽ•‰È‚É‚¨‚¯‚é“™‰·ˆâ“`Žq‘•–@‚ð—˜—p‚µ‚½ƒƒ`ƒVƒŠƒ“‘Ï«‹Û‚ÌV‚µ‚¢ŒŸ¸–@‚Ì—L—p«‚ÌŒŸØ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KoideYasushi en-aut-sei=Koide en-aut-mei=Yasushi kn-aut-name=¬oNŽj kn-aut-sei=¬o kn-aut-mei=NŽj aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰ÈˆãŽt‚ÌA‹Æ󋵂Æf—Ëô”­Ž–ŒÌ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OnoHiroshi en-aut-sei=Ono en-aut-mei=Hiroshi kn-aut-name=¬–ìœA kn-aut-sei=¬–ì kn-aut-mei=œA aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=‘¾—z“d’r‚ð•t—^‚µ‚½–_󔼓±‘ÌŽ_‰»ƒ`ƒ^ƒ“‚ÌŽ•‰È—Õ°‰ž—p‚ւ̉”\«|Streptococcus mutans‚ɑ΂·‚éŒõG”}Œø‰Ê| en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IshiHarumi en-aut-sei=Ishi en-aut-mei=Harumi kn-aut-name=Έä•q”ü kn-aut-sei=Έä kn-aut-mei=•q”ü aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue= article-no= start-page=105 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Granularity of Asymmetric Screen-Film System kn-title=”ñ‘ÎÌ‘Š´Ž†ƒtƒBƒ‹ƒ€Œn‚Ì—±ó« en-subtitle= kn-subtitle= en-abstract=We have examined a factor affecting the Wiener spectrum measurement of double-emulsion film. An asymmetric screen-film system (Kodak HC/INSIGHT system) was used in this study. The results indicated that the total Wiener spectra of double-emulsion films are higher than the sum of spectra obtained with the front emulsion and back emulsion separately. These differences are attributed to the arrangement of the optical system of the microdensitometer used to measure and the structure of double-emulsion film. kn-abstract=”ñ‘ÎÌ‘Š´Ž†ƒtƒBƒ‹ƒ€Œn‚ɂ‚¢‚ÄA—¼–Ê“û܃tƒBƒ‹ƒ€‚̃EƒBƒi[ƒXƒyƒNƒgƒ‹‘ª’è‚É‹y‚Ú‚·‰e‹¿‚ðŒŸ“¢‚µ‚½B”Z“x0.5`2.5‚̃mƒCƒYŽŽ—¿‚̃tƒƒ“ƒg“ûÜAƒoƒbƒN“ûÜAŽxŽ‘Ì‘w‚»‚ꂼ‚ê‚Å‘ª’肵‚½ƒXƒyƒNƒgƒ‹‚̘a‚ÆA—¼–Ê“¯Žž‚É‘ª’肵‚½‘SƒXƒyƒNƒgƒ‹‚Æ‚ð”äŠr‚µ‚½B‚»‚ÌŒ‹‰ÊA‘SƒEƒBƒi[ƒXƒyƒNƒgƒ‹‚Ì’l‚ÍAƒtƒƒ“ƒg“ûÜAƒoƒbƒN“û܂̘a‚æ‚è‚‚­‚È‚Á‚½B‚Ü‚½AŽŽ—¿”Z“x‚ª‚‚¢‚Ù‚ÇA‚»‚Ì·‚Í‘å‚«‚­‚È‚Á‚½B‚±‚ê‚ç‚ÍAƒ}ƒCƒNƒƒfƒ“ƒVƒgƒ[ƒ^‚ÌŒõŠwŒn‚Ì”z’u‚Æ—¼–Ê“û܃tƒBƒ‹ƒ€‚Ì\‘¢‚É‹Nˆö‚µ‚Ä‚¢‚éB‚µ‚½‚ª‚Á‚ÄA”ñ‘Î̃VƒXƒeƒ€‚̂悤‚ɃtƒBƒ‹ƒ€‚Ì‘O–Ê‚ÆŒã–Ê‚Å“Á«‚𕪂¯‚Äl‚¦‚éê‡A’ˆÓ‚ð—v‚·‚éB en-copyright= kn-copyright= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=–{“cv kn-aut-sei=–{“c kn-aut-mei=v aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=‹g“c² kn-aut-sei=‹g“c kn-aut-mei=² aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=’†‘ºLŽ} kn-aut-sei=’†‘º kn-aut-mei=LŽ} aut-affil-num=3 ORCID= en-aut-name=MimuraSeiichi en-aut-sei=Mimura en-aut-mei=Seiichi kn-aut-name=ŽO‘º½ˆê kn-aut-sei=ŽO‘º kn-aut-mei=½ˆê aut-affil-num=4 ORCID= en-aut-name=KadohisaSigefumi en-aut-sei=Kadohisa en-aut-mei=Sigefumi kn-aut-name=–å‹v”É•¶ kn-aut-sei=–å‹v kn-aut-mei=”É•¶ aut-affil-num=5 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=ŽOã‘×—² kn-aut-sei=ŽOã kn-aut-mei=‘×—² aut-affil-num=6 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=7 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=’|“à’ms kn-aut-sei=’|“à kn-aut-mei=’ms aut-affil-num=8 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=10 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” en-keyword=”ñ‘ÎÌ‘Š´Ž†ƒtƒBƒ‹ƒ€Œn (asymmetric screen-film system) kn-keyword=”ñ‘ÎÌ‘Š´Ž†ƒtƒBƒ‹ƒ€Œn (asymmetric screen-film system) en-keyword=—¼–Ê“û܃tƒBƒ‹ƒ€ (double-emulsion film) kn-keyword=—¼–Ê“û܃tƒBƒ‹ƒ€ (double-emulsion film) en-keyword=ƒEƒBƒi[ƒXƒyƒNƒgƒ‹ (Wiener spectrum) kn-keyword=ƒEƒBƒi[ƒXƒyƒNƒgƒ‹ (Wiener spectrum) en-keyword=—±ó« (granularity) kn-keyword=—±ó« (granularity) en-keyword=ƒ}ƒCƒNƒƒfƒ“ƒVƒgƒ[ƒ^ (microdensitometer) kn-keyword=ƒ}ƒCƒNƒƒfƒ“ƒVƒgƒ[ƒ^ (microdensitometer) END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=75 end-page=82 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analysis of Tempormandibular Joint by Image Processing -Discrimination of Condylar Position- kn-title=‰æ‘œˆ—‚É‚æ‚éŠ{ŠÖ߂̉ðÍ \‰ºŠ{“ªˆÊ‚Ì”»•Ê\ en-subtitle= kn-subtitle= en-abstract= kn-abstract=Tomography is clinically useful in the diagnosis of the temporomandibular joint (TMJ) syndrome. The TMJ is formed by the condyle and the glenoid fossa, and there exists TMJ space between them. Image processing was employed in the present study, and the reference points of the condyle and the glenoid fossa were determined from the tomogram. Subsequently, the TMJ space was measured automatically in the image analysis. The TMJs of 98 patients were examined practically and the characteristics of each result were studied. There is a possibility of discriminating an abnormal condylar position from a normal one by making use of the TMJ space and the distance between two reference points. en-copyright= kn-copyright= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=1 ORCID= en-aut-name=GotouSachiko en-aut-sei=Gotou en-aut-mei=Sachiko kn-aut-name=Œã“¡²’mŽq kn-aut-sei=Œã“¡ kn-aut-mei=²’mŽq aut-affil-num=2 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=’†‹Ë‹`’‰ kn-aut-sei=’†‹Ë kn-aut-mei=‹`’‰ aut-affil-num=3 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=’†‘ºLŽ} kn-aut-sei=’†‘º kn-aut-mei=LŽ} aut-affil-num=4 ORCID= en-aut-name=ShibuyaKouichi en-aut-sei=Shibuya en-aut-mei=Kouichi kn-aut-name=a’JŒõˆê kn-aut-sei=a’J kn-aut-mei=Œõˆê aut-affil-num=5 ORCID= en-aut-name=YamadaToshiharu en-aut-sei=Yamada en-aut-mei=Toshiharu kn-aut-name=ŽR“crŽ¡ kn-aut-sei=ŽR“c kn-aut-mei=rŽ¡ aut-affil-num=6 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=7 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=ŽOã‘×—² kn-aut-sei=ŽOã kn-aut-mei=‘×—² aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” en-keyword=Condylar Position kn-keyword=Condylar Position en-keyword=Temporomandibular Joint Space kn-keyword=Temporomandibular Joint Space en-keyword=Image Processing kn-keyword=Image Processing en-keyword=Tomogram kn-keyword=Tomogram en-keyword=Discrimination kn-keyword=Discrimination END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=99 end-page=104 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Physical Image Quality of Rapid Processing Films kn-title=v‘¬ˆ——pXüƒtƒBƒ‹ƒ€‚Ì•¨—“Á« en-subtitle= kn-subtitle= en-abstract= kn-abstract=The imaging properties of Konica "new" SR series films and "old" MG-SR series films for rapid processing were measured in combination with green-emitting intensifying screens. The measured image quality prarameters include: characteristic curve, modulation transfer function (MTF) and Wiener spectrum. The relative speeds of the new SR series systems were slower than those of the old MG-SR series systems from 10 to 25%. The MTF's of the new systems were generally comparable to those of the old systems, except that SR-G system was improved with an increase of approximately 10%. In the Wiener spectrum measurement, however, the new systems showed from 10 to 35% decrease in low-frequency noise. en-copyright= kn-copyright= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=‹g“c² kn-aut-sei=‹g“c kn-aut-mei=² aut-affil-num=1 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=–{“cv kn-aut-sei=–{“c kn-aut-mei=v aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=’†‘ºLŽ} kn-aut-sei=’†‘º kn-aut-mei=LŽ} aut-affil-num=3 ORCID= en-aut-name=AriokaTadashi en-aut-sei=Arioka en-aut-mei=Tadashi kn-aut-name=—L‰ª‹§ kn-aut-sei=—L‰ª kn-aut-mei=‹§ aut-affil-num=4 ORCID= en-aut-name=KobashiToshimi en-aut-sei=Kobashi en-aut-mei=Toshimi kn-aut-name=¬‹´—˜”ü kn-aut-sei=¬‹´ kn-aut-mei=—˜”ü aut-affil-num=5 ORCID= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=’|“à’ms kn-aut-sei=’|“à kn-aut-mei=’ms aut-affil-num=6 ORCID= en-aut-name=MikamiYasutaka en-aut-sei=Mikami en-aut-mei=Yasutaka kn-aut-name=ŽOã‘×—² kn-aut-sei=ŽOã kn-aut-mei=‘×—² aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” en-keyword=Rapid Processing Films kn-keyword=Rapid Processing Films en-keyword=Image Quality kn-keyword=Image Quality en-keyword=Characteristic Curve kn-keyword=Characteristic Curve en-keyword=MTF kn-keyword=MTF en-keyword=Wiener Spectrum kn-keyword=Wiener Spectrum END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=81 end-page=88 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920205 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=RESOLUTION PROPERTIES OF CRT MONITORS kn-title=CRTƒ‚ƒjƒ^‚̉𑜓Á« en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have developed a new technique for measuring the modulation transfer function (MTF) of a cathode ray tube (CRT) monitor. The "nominal" MTF was measured by displaying a line image of a width of one pixel on the CRT monitor using the pattern generator. We also measured the effective pixel width. In order to obtain the "actual" MTF, the nominal MTF was divided by the sinc function which is the Fourier transform of the effective pixel width. The results indicate that the corrected MTF@converges to the constant value as the effective pixel width is narrower. Thus, the actual MTFs were determined and compared in the horizontal direction for two CRT monitors. en-copyright= kn-copyright= en-aut-name=TakeuchiTomoyuki en-aut-sei=Takeuchi en-aut-mei=Tomoyuki kn-aut-name=’|“à’ms kn-aut-sei=’|“à kn-aut-mei=’ms aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=‹g“c² kn-aut-sei=‹g“c kn-aut-mei=² aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=3 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=4 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=’†‘ºLŽ} kn-aut-sei=’†‘º kn-aut-mei=LŽ} aut-affil-num=5 ORCID= en-aut-name=KishiKanji en-aut-sei=Kishi en-aut-mei=Kanji kn-aut-name=ŠÝŠ²“ñ kn-aut-sei=ŠÝ kn-aut-mei=Š²“ñ aut-affil-num=6 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=•½–ØË•v kn-aut-sei=•½–Ø kn-aut-mei=Ë•v aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=2 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•úŽËüˆãŠw‹³Žº en-keyword=CRT Monitor kn-keyword=CRT Monitor en-keyword=Resolution kn-keyword=Resolution en-keyword=Effective Pixel Width kn-keyword=Effective Pixel Width en-keyword=Modulation Transfer Function (MTF) kn-keyword=Modulation Transfer Function (MTF) END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=7 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Physical Properties of Screen-Film Systems - New System for Chest Radiography - kn-title=‘Š´Ž†ƒtƒBƒ‹ƒ€Œn‚Ì•¨—“Á« \‹¹•”—pVƒVƒXƒeƒ€\ en-subtitle= kn-subtitle= en-abstract=The new three screen-film systems, Kodack INSIGHT system HC/IT-1, Fuji AD system HG-M/UR-1, and Konica EX system XG-S/ES-C for chest radiography were evaluated. In addition, the conventional system Fuji HR-4/Super HR-S was measured for comparison with new systems. The evaluation method is as follows. The image quality characteristics, speed, contrast, resolution and granularity were measured. The sensitivity and contrast were determined by measuring the MTF (modulation transfer function) and NCTF (normalized contrast transfer function). The granularity was estimated by measuring the Wiener spectrum. The speed of the new systems were improved by 22% to 73%. The dinsities at the maximum gradient value were shifted to high density (2.0-2.7). However, they had 10% to 30% less resolution. The other hand, the granularities were improved by 21% to 37% at 1.0 density. These results suggested that the emphasis of new systems was put on improving the image quality of mediastinum region, maintaining performance of the conventional system. kn-abstract=‹¹•”ê—p‚ÌV‚µ‚¢‘Š´Ž†^ƒtƒBƒ‹ƒ€ƒVƒXƒeƒ€‚ɂ‚¢‚Ä•¨—“I‰æŽ¿“Á«‚𑪒肵A]—ˆ‚̃VƒXƒeƒ€‚Æ”äŠr‚ðs‚Á‚½B‘ª’肵‚½VƒVƒXƒeƒ€‚ÍA“ú–{ƒRƒ_ƒbƒN‚̃Cƒ“ƒTƒCƒgƒVƒXƒeƒ€‚©‚çHC/IT-1A•xŽmƒƒfƒBƒJƒ‹ƒVƒXƒeƒ€‚ÌADƒVƒXƒeƒ€‚©‚çHG-M/UR-1AƒRƒjƒJ‚ÌEXƒVƒXƒeƒ€‚©‚çXG-S/ES-C ‚Å‚ ‚éB]—ˆ‚̃VƒXƒeƒ€‚Æ‚µ‚Ä•xŽmƒƒfƒBƒJƒ‹ƒVƒXƒeƒ€‚ÌHR-4/Super HR-S ‚ðŽg—p‚µ‚½B‚»‚ÌŒ‹‰ÊAVƒVƒXƒeƒ€‚Í22`73“Š´“x‚Í‚‚­A“Á«‹Èü‚É‚¨‚¢‚Ä‚Í’á”Z“x•”‚ðŽ‚¿ã‚°AÅ‘åƒRƒ“ƒgƒ‰ƒXƒg‚Í‚”Z“x‘¤‚ɃVƒtƒg‚µ‚Ä‚¢‚½B‹óŠÔŽü”g”2cycles/mm‚Å‘Š‘ΑN‰s“x‚ð”äŠr‚·‚é‚ÆAVƒVƒXƒeƒ€‚ª10`30“’ö“x‚̒ቺ‚Æ‚È‚Á‚Ä‚¢‚½BƒmƒCƒY‚ÍA”Z“x1.0‚ÅVƒVƒXƒeƒ€‚ª35`46“‚ÌŒ¸­‚Æ‚È‚Á‚½BˆÈã‚æ‚èAVƒVƒXƒeƒ€‚ÍAcŠu•”‚Ì”Z“x‚ðã‚°A—±ó«‚̉ü‘P‚ðdŽ‹‚µ‚½ÝŒv‚Æ‚È‚Á‚Ä‚¢‚邱‚Æ‚ª•ª‚©‚Á‚½B en-copyright= kn-copyright= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=Œã“¡²’mŽq kn-aut-sei=Œã“¡ kn-aut-mei=²’mŽq aut-affil-num=1 ORCID= en-aut-name=YoshidaAkira en-aut-sei=Yoshida en-aut-mei=Akira kn-aut-name=‹g“c² kn-aut-sei=‹g“c kn-aut-mei=² aut-affil-num=2 ORCID= en-aut-name=NakamuraNobue en-aut-sei=Nakamura en-aut-mei=Nobue kn-aut-name=’†‘ºLŽ} kn-aut-sei=’†‘º kn-aut-mei=LŽ} aut-affil-num=3 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=ŠÛŽR•q‘¥ kn-aut-sei=ŠÛŽR kn-aut-mei=•q‘¥ aut-affil-num=4 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=“Œ‹`° kn-aut-sei=“Œ kn-aut-mei=‹`° aut-affil-num=5 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=a’JŒõˆê kn-aut-sei=a’J kn-aut-mei=Œõˆê aut-affil-num=6 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=’†‹Ë‹`’‰ kn-aut-sei=’†‹Ë kn-aut-mei=‹`’‰ aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=™“cŸ•F kn-aut-sei=™“c kn-aut-mei=Ÿ•F aut-affil-num=8 ORCID= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name=–{“cv kn-aut-sei=–{“c kn-aut-mei=v aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=2 en-affil= kn-affil=L“‡Œ§—§•ÛŒ’•ŸŽƒ’ZŠú‘åŠw•”•úŽËü‹Zp‰ÈŠw‰È affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠwŽ•Šw•”•‘®•a‰@Ž•‰È•úŽËü‰È affil-num=4 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=5 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=6 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=7 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=8 en-affil= kn-affil=‰ªŽR‘åŠwˆã—ËZp’ZŠú‘åŠw•”f—ÕúŽËü‹ZpŠw‰È affil-num=9 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•‘®•a‰@’†‰›•úŽËü•” en-keyword=‘Š´Ž†ƒtƒBƒ‹ƒ€Œn (screen-film system) kn-keyword=‘Š´Ž†ƒtƒBƒ‹ƒ€Œn (screen-film system) en-keyword=•¨—“Á« (physical properties) kn-keyword=•¨—“Á« (physical properties) en-keyword=Š´“x (speed (film sensitivity)) kn-keyword=Š´“x (speed (film sensitivity)) en-keyword=ƒRƒ“ƒgƒ‰ƒXƒg (contrast) kn-keyword=ƒRƒ“ƒgƒ‰ƒXƒg (contrast) en-keyword=‘N‰s“x (resolution) kn-keyword=‘N‰s“x (resolution) en-keyword=—±ó« (granularity) kn-keyword=—±ó« (granularity) END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=1 article-no= start-page=25 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001116 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ž•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg“®—h‘ª’è‘•’u‚ÌŠJ”­ kn-title=Development of a dental implant movement checker en-subtitle= kn-subtitle= en-abstract=—Õ°Ž•‰È‚É‚¨‚¢‚ÄCŽ•‚Ì“®—h“xf¸‚ª“úí“I‚És‚í‚ê‚Ä‚¢‚é‚Ì‚Æ“¯‚¶‚悤‚ÉC‹ß”Ns‚í‚ê‚é‚悤‚É‚È‚Á‚Ä‚«‚½Ž•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒgŽ{p‚É‚¨‚¢‚Ä‚àC‚»‚ÌA—§•]‰¿‚Íd—v‚Å‚ ‚éBŽ•‚Ì“®—h‚ÍCŽ•‚ÌŽ¡—ÃŒv‰æ‚É‚¨‚¢‚ÄC‚Ü‚½—\Œã‚Ì•]‰¿‚É‚¨‚¢‚Ä‚àd—v‚Èî•ñ‚ð—^‚¦‚Ä‚­‚ê‚éB–{Œ¤‹†‚Å‚ÍC‚»‚ÌA—§•]‰¿‚ðs‚¤‚½‚ß‚ÉCƒCƒ“ƒvƒ‰ƒ“ƒg‚Ì“®—h‚É’…–Ú‚µ‚½B“®—h‚ðŠÈ•Ö‚É‚©‚Â’è—Ê“I‚É‘ª’è‚·‚邽‚ß‚ÉC’˜ŽÒ‚炪‚·‚Å‚ÉŠJ”­‚µ‚½T|MƒeƒXƒ^iTooth Mobility testerj‚ð‰ü—Ç‚µ‚ÄCIMƒ`ƒFƒbƒJiImplant Mobility Checkerj‚ðŠJ”­‚µ‚½BIMƒ`ƒFƒbƒJ‚Í‘ª’èƒvƒ[ƒu‚Æ‘•Ší‚Ȃǂ̃Cƒ“ƒ^ƒtƒF[ƒXC‰‰ŽZˆ——p‚̃m[ƒgƒpƒ\ƒRƒ“‚©‚ç\¬‚³‚ê‚éB‘ª’èƒvƒ[ƒu‚͈³“d‘fŽq‚ð2–‡d‚Ë‚½ƒoƒCƒ‚ƒ‹ƒt\‘¢‚ÅC’PˆêŽü”g”‚ÌU“®‹ì“®‚ƉÁ‘¬“xŒŸo‚ðs‚¢CŒûo“à‚Å‚à‘ª’肪‚Å‚«‚é‚قǂɬŒ^‚ÉÝŒv‚µ‚½Bƒm[ƒgƒpƒ\ƒRƒ“‚Å‚Í“¾‚ç‚ꂽ‰Á‘¬“xM†‚ðƒf[ƒ^ˆ—‚µCIM’l‚ðŽZo‚·‚éBIM’l‚ÍC‘ª’èŽü”g”‚Æ‹ì“®—Í‚ªˆê ’è‚Ìê‡CƒCƒ“ƒvƒ‰ƒ“ƒgŽüˆÍ‚Ì‹@ŠBƒ‚ƒrƒŠƒeƒB‚É”ä—á‚·‚é‚Ì‚ÅCƒCƒ“ƒvƒ‰ƒ“ƒg‚Ì“®—h‚ð”’l‰»‚·‚邱‚Æ‚ª‚Å‚«‚éB“à‰Â“®«‹@\‚ð‚à‚ÂIMZƒ^ƒCƒv‚̃Cƒ“ƒvƒ‰ƒ“ƒg‚ð–„A‚µ‚½ƒ‚ƒfƒ‹‚ð»ì‚µC‚»‚ÌIM’l‚𑪒肵‚½BƒCƒ“ƒvƒ‰ƒ“ƒgŽüˆÍ‚ÌÞ—¿iƒ‚ƒ‹ƒeƒm(@)j‚Ìd‚³‚ð•Ï‚¦‚½2Ží—ނ̃‚ƒfƒ‹‚ð컂µ‚½‚Æ‚±‚ëCŽ•‰Èˆã‚É‚æ‚é—Õ°“I“®—h“xf¸‚Í‚¢‚¸‚ê‚àM0‚Å‚ ‚Á‚½‚ªC–{ƒ`ƒFƒbƒJ‚É‚æ‚Á‚Ä‚»‚Ì“®—h‚Ì·‚𑪒肵‚½‚Æ‚±‚ëCIM’l‚Í29‚Æ58‚Æ‚È‚èC‹qŠÏ“I‚É“®—h‚Ì·‚ð•]‰¿‚·‚邱‚Æ‚ª‚Å‚«‚½BŽŽì‚µ‚½IMƒ`ƒFƒbƒJ‚Å‘ª’肵‚½‚Æ‚±‚ëCˆêŽ•‚Ì‘ª’莞ŠÔ‚Í–ñ15•bˆÈ‰º‚Å‚ ‚èC‚Ü‚½‘ª’è‚̂΂ç‚‚«‚ÍpŽÒ“à‚Å•½‹Ï6“ˆÈ‰ºC‚Ü‚½pŽÒŠÔ‚Å6“ˆÈ‰º‚Å‚ ‚Á‚½Bˆê•ûC]—ˆ‚̃AƒiƒƒOŒ^T|MƒeƒXƒ^‚Æ”äŠr‚µ‚½‚Æ‚±‚ëC“V‘RŽ•‚Ì‘ª’è‚É‚¨‚¢‚ÄC‘ª’è‚̂΂ç‚‚«‚Í51“C‘ª’莞ŠÔ‚Í61“Œ¸­‚³‚¹‚邱‚Æ‚ª‚Å‚«‚½B]‚Á‚ÄCIMƒ`ƒFƒbƒJ‚Í\•ª‚È‘ª’踓x‚ðŠm•Û‚Å‚«‚Ä‚¨‚èC¡ŒãC—Õ°‚Å‚ÌŽŽ—p‚ðs‚¢‚½‚¢‚Æl‚¦‚éB kn-abstract=Evaluation of dental implantation is very important because it gives useful information for both planning the dental treatment and evaluating of prognosis. This study aimed at improving our previously developed Tooth Mobility (TM) tester and developing a dental implant movement (IM) checker. The measuring probe included a bimorph transducer of two piezoelectric elements. It was actuated by single frequency and detected tooth acceleration. The acceleration signal was processed and the IM score was calculated in PC. Two artificial implant models in which IMZ implant was buried with different elasticity of surrounding (molteno(@)) were used to examine the performance of the IM checker. The IM scores obtained in the models were 29 and 58. The measurement time was below 15 seconds. The average of measurement variation of one operator was below 6% and the average variation among five operators was below also 6%. The IM checker reduced a measurement variation by 51% and a measuring time by 61% compared with those of the TM tester in natural teeth. The newly developed IM checker had sufficient measuring reliability and we could objectively estimate the implant movement in dental clinics. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=‰ª‹v—Y kn-aut-sei=‰ª kn-aut-mei=‹v—Y aut-affil-num=1 ORCID= en-aut-name=OnoKoichi en-aut-sei=Ono en-aut-mei=Koichi kn-aut-name=¬–ì_ˆê kn-aut-sei=¬–ì kn-aut-mei=_ˆê aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=WijayaSastra Kusuma kn-aut-sei=Wijaya kn-aut-mei=Sastra Kusuma aut-affil-num=3 ORCID= en-aut-name=SarataniKeiji en-aut-sei=Saratani en-aut-mei=Keiji kn-aut-name=X’JŒ[Ž¡ kn-aut-sei=X’J kn-aut-mei=Œ[Ž¡ aut-affil-num=4 ORCID= en-aut-name=KawazoeTakayoshi en-aut-sei=Kawazoe en-aut-mei=Takayoshi kn-aut-name=ì“Yꟕj kn-aut-sei=ì“Y kn-aut-mei=ꟕj aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠwˆãŠw•”•ÛŒ’Šw‰ÈŒŸ¸‹Zp‰ÈŠwêU affil-num=2 en-affil= kn-affil=‡ŠƒGƒvƒ\ƒ“EƒvƒŠƒ“ƒ^ÝŒvƒOƒ‹[ƒv affil-num=3 en-affil= kn-affil=‰ªŽR‘åŠw‘åŠw‰@Ž©‘R‰ÈŠwŒ¤‹†‰È’m”\ŠJ”­‰ÈŠwêU affil-num=4 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ affil-num=5 en-affil= kn-affil=‘å㎕‰È‘åŠw—LŽ••â’Ô™ù‡ŠwuÀ en-keyword=tooth mobility (Ž•‚Ì“®—h) kn-keyword=tooth mobility (Ž•‚Ì“®—h) en-keyword=mechanical mobility (‹@ŠBƒ‚ƒrƒŠƒeƒB) kn-keyword=mechanical mobility (‹@ŠBƒ‚ƒrƒŠƒeƒB) en-keyword=dental implant (ƒCƒ“ƒvƒ‰ƒ“ƒg) kn-keyword=dental implant (ƒCƒ“ƒvƒ‰ƒ“ƒg) en-keyword=manual examination (Gf) kn-keyword=manual examination (Gf) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ˆêŽ•‰Èˆã‰@‚É‚¨‚¯‚éƒR[ƒkƒXƒeƒŒƒXƒR[ƒv‹`Ž•‚Æ•”•ª°‹`Ž•‚Ì—\Œã’²¸‚Ì”äŠr en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShimamuraKoichi en-aut-sei=Shimamura en-aut-mei=Koichi kn-aut-name=“ˆ‘º_ˆê kn-aut-sei=“ˆ‘º kn-aut-mei=_ˆê aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ˆêŽ•‰Èˆã‰@‚É‚¨‚¯‚骊ǎ¡—Â̗\Œã’²¸ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TsujiKozo en-aut-sei=Tsuji en-aut-mei=Kozo kn-aut-name=’Òk‘¢ kn-aut-sei=’Ò kn-aut-mei=k‘¢ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg‚̶‘Ì‘gD‚Æ‚Ì—Z‡«‚ÉŠÖ‚·‚éŠî‘b“IŒ¤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= 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en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsumuraJun en-aut-sei=Matsumura en-aut-mei=Jun kn-aut-name=¼‘º~ kn-aut-sei=¼‘º kn-aut-mei=~ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ž•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒg‚̈À’è«‚¨‚æ‚ÑŒ`óƒAƒZƒXƒƒ“ƒg‚Ì‚½‚ß‚Ì‹@ŠBƒ‚ƒrƒŠƒeƒB‹Z–@‚ÉŠÖ‚·‚錤‹† kn-title=Mechanical Mobility Technique for Stability and Geometry Assessment of Dental Implant en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WijayaSastra Kusuma en-aut-sei=Wijaya en-aut-mei=Sastra Kusuma kn-aut-name=ƒEƒBƒWƒƒƒ„ƒTƒXƒgƒ‰ ƒNƒXƒ} kn-aut-sei=ƒEƒBƒWƒƒƒ„ kn-aut-mei=ƒTƒXƒgƒ‰ ƒNƒXƒ} aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‹°•|‚Ì—\–h‚ÉŠÖ‚·‚és“®‰ÈŠw“IŒ¤‹† Ž¿–⎆–@‚É‚æ‚é•]’èŽÚ“x‚ÌlˆÄ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=šâ“à’q˜Y kn-aut-sei=šâ“à kn-aut-mei=’q˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‚É‚¨‚¯‚és“®‰ÈŠw [ƒXƒgƒŒƒX”F’m‚ª•@•””畆•\–ʉ·“x‚É‹y‚Ú‚·‰e‹¿[ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=•½ŠÔ‰ë”Ž kn-aut-sei=•½ŠÔ kn-aut-mei=‰ë”Ž aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‚É‚¨‚¯‚é™ù‡‹@”\‚Æ‘Sg‹@”\‚ÉŠÖ‚·‚錤‹† -¬’·‚Æ™ù‡,dS“®—h‚Ì‘ŠŒÝŠÖŒW- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HiguchiMasaru en-aut-sei=Higuchi en-aut-mei=Masaru kn-aut-name=”óŒû›’ kn-aut-sei=”óŒû kn-aut-mei=›’ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‚É‚¨‚¯‚és“®‰ÈŠw -—\Šú•sˆÀ‚Æ•@•””畆•\–ʉ·‚ÌŠÖŒW- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=DoiNorikatsu en-aut-sei=Doi en-aut-mei=Norikatsu kn-aut-name=“y”ì”ÍŸ kn-aut-sei=“y”ì kn-aut-mei=”ÍŸ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=¬Ž™Ž•‰È—Õ°‚É‚¨‚¯‚és“®‰ÈŠw ƒT[ƒ‚ƒOƒ‰ƒt¨‚É‚æ‚錟“¢ kn-title=Behavioral science research in Pediatric Dentistry A Thermographic investigation en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=“cŒûƒ}ƒ‹ƒZ[ƒ‰•¶‘ã kn-aut-sei=“cŒû kn-aut-mei=ƒ}ƒ‹ƒZ[ƒ‰•¶‘ã aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=¬Ž™Ž•‰È—Õ°‚É‚¨‚¯‚鎕‰È‹°•|‚ÉŠÖ‚·‚és“®‰ÈŠw•@•””畆•\–ʉ·“x‚Æs“®‚Æ‚ÌŠÖ˜A« kn-title=Behavioral science on dental fear in pediatric dentistry : Relationship between behavior and the nasal skin temperature en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=’‡ˆäáŠG kn-aut-sei=’‡ˆä kn-aut-mei=áŠG aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‚É‚¨‚¯‚és“®‰ÈŠw -•sˆÀ¤s“®‚¨‚æ‚Ñ•@•””畆•\–ʉ·“x‚Æ‚ÌŠÖŒW- en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=’†‘º—²Žq kn-aut-sei=’†‘º kn-aut-mei=—²Žq aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=¬Ž™Ž•‰È‚É‚¨‚¯‚és“®‰ÈŠw ƒoƒCƒIƒ‚ƒjƒ^ƒŠƒ“ƒOƒVƒXƒeƒ€‚ÌŠJ”­ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‘å’¬kŽs kn-aut-sei=‘å’¬ kn-aut-mei=kŽs aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=¬Ž™Ž•‰È‚É‚¨‚¯‚és“®‰ÈŠw ¸_”­’B‚Æ•@•””畆•\–ʉ·“x•Ï‰»—lŽ®‚Æ‚ÌŠÖ˜A« en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=ŽRªG•¶ kn-aut-sei=ŽRª kn-aut-mei=G•¶ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È—pƒ|[ƒZƒŒƒ“‚ÆÚ’…«ƒŒƒWƒ“‚ÌÚ’…‚É‚¨‚¯‚é”í’…–ʈ—‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=¡ˆä½ kn-aut-sei=¡ˆä kn-aut-mei=½ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19901031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=•¡‡“dÍ‚É‚æ‚鎕‰È—p‹à‘®‚̔풅–ʈ—–@‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‹ß“¡NO kn-aut-sei=‹ß“¡ kn-aut-mei=NO aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ž•‰È•sˆÀ‚Ì•]‰¿‚ÉŠÖ‚·‚錤‹† “Á«•sˆÀ‚Æó‘Ô•sˆÀ‚¨‚æ‚Ñ•@•””畆•\–ʉ·“x‚Æ‚ÌŠÖ˜A« kn-title=The assessment of dental anxiety:its relationships with trait anxiety, state anxiety,and nasal skin temperature en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‹g“c“oŽuŽq kn-aut-sei=‹g“c kn-aut-mei=“oŽuŽq aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‹¸³—pƒvƒ‰ƒXƒ`ƒbƒNƒuƒ‰ƒPƒbƒg‚̔풅–ʈ—‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=ŠÇ‘‹­ kn-aut-sei=ŠÇ kn-aut-mei=‘‹­ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ž•‰È‹ÇŠ–ƒŒŽ{sŽž‚ÌŒŒŸ÷ƒJƒeƒR[ƒ‹ƒAƒ~ƒ“”Z“x‚ÆzŠÂ“®‘Ô‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=ŠOŽR“O kn-aut-sei=ŠOŽR kn-aut-mei=“O aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1969 dt-pub=19691231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ŒûoŠà‚ÆŽ•‰È“I—Uˆö‚ÉŠÖ‚·‚錤‹† en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‚—œ‹g˜Y kn-aut-sei=‚—œ kn-aut-mei=‹g˜Y aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19861231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Vitallim(ƒRƒoƒ‹ƒg¥ƒNƒƒ€‡‹à)‚ÌŽ•‰ÈƒCƒ“ƒvƒ‰ƒ“ƒgÞ‚Æ‚µ‚Ä‚Ì“K‡«‚ÉŠÖ‚·‚éŽÀŒ±“IŒ¤‹† kn-title=Vitallium en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=‚¼‰p–ç kn-aut-sei=‚¼ kn-aut-mei=‰p–ç aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=‰ªŽR‘åŠw END