start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160309 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Newsletter from Course for Prospective Museum Workers, Faculty of Letters, Okayama University kn-title=学芸員課程 Newsletter 第6号 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=光本順 kn-aut-sei=光本 kn-aut-mei=順 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=城永妙子 kn-aut-sei=城永 kn-aut-mei=妙子 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=竹内里奈 kn-aut-sei=竹内 kn-aut-mei=里奈 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=串田真緒 kn-aut-sei=串田 kn-aut-mei=真緒 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田彩季 kn-aut-sei=塩田 kn-aut-mei=彩季 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=近藤智香 kn-aut-sei=近藤 kn-aut-mei=智香 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=十川拓 kn-aut-sei=十川 kn-aut-mei=拓 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=文学部 affil-num=2 en-affil= kn-affil=文学部行動科学専修コース affil-num=3 en-affil= kn-affil=文学部言語文化学専修コース affil-num=4 en-affil= kn-affil=文学部哲学芸術学専修コース affil-num=5 en-affil= kn-affil=文学部歴史文化学専修コース affil-num=6 en-affil= kn-affil=文学部歴史文化学専修コース affil-num=7 en-affil= kn-affil=文学部歴史文化学専修コース END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=59 end-page=73 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=保育施設における幼児の描画活動に見るキャラクター表現と図形模写能力の関連性 en-subtitle= kn-subtitle= en-abstract=This study discusses the relationship between the act of drawing characters and the shapes copying ability of preschoolers observed in drawing activities. For the purpose of elucidating the effects of drawing characters on the children’s shapes copying ability, preschoolers were divided into the following three groups and their shapes copying ability was comparatively examined: 1) those who draw characters, 2) those who do not draw characters but draw in a general way, 3) those who do not participate in drawing activities on their own initiative. As a result, it was elucidated that children who draw characters and children who draw in a general way both had the same level of shapes copying ability. Accordingly, as with the act of drawing in a general way, the act of drawing characters may be regarded as one of the expression forms for building drawing experience. kn-abstract=本論は,幼児の描画活動におけるキャラクター表現と図形模写能力の関連性について考察する。そこで,キャラクター表現の有無が,図形模写能力に与える影響を明らかにするため,①キャラクター表現を行う幼児,②キャラクターは描かないが一般的な描画を行う幼児,③自発的に描画活動を行わない幼児,の3群に分け図形模写能力を比較検討した。その結果,キャラクター表現をする幼児も,一般的な描画をする幼児と同水準の図形模写能力を有していることが,明らかになった。このことから,キャラクター表現は,一般の描画表現と同様に,描画経験の蓄積となる表現形式の1つになり得ると考えられる。 en-copyright= kn-copyright= en-aut-name=Shiota(Seiyo)Yui en-aut-sei=Shiota(Seiyo) en-aut-mei=Yui kn-aut-name=塩田(青陽)結 kn-aut-sei=塩田(青陽) kn-aut-mei=結 aut-affil-num=1 ORCID= en-aut-name=TakahashiKei en-aut-sei=Takahashi en-aut-mei=Kei kn-aut-name=髙橋慧 kn-aut-sei=髙橋 kn-aut-mei=慧 aut-affil-num=2 ORCID= en-aut-name=KatayamaMika en-aut-sei=Katayama en-aut-mei=Mika kn-aut-name=片山美香 kn-aut-sei=片山 kn-aut-mei=美香 aut-affil-num=3 ORCID= affil-num=1 en-affil=Fund-contributed medical corporation Ryutenkai Katagi Neurosurgery Sigma Daycare Center kn-affil=基金拠出型医療法人隆典会片木脳神経外科内シグマ託児所 affil-num=2 en-affil=The Faculty of Ch ildhood Education, Kurashiki Sakuyo University kn-affil=くらしき作陽大学子ども教育学部 affil-num=3 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=保育施設(preschool facility) kn-keyword=保育施設(preschool facility) en-keyword=幼児(preschoolers) kn-keyword=幼児(preschoolers) en-keyword=描画活動(drawing activities) kn-keyword=描画活動(drawing activities) en-keyword=キャラクター表現(drawing characters) kn-keyword=キャラクター表現(drawing characters) en-keyword=図形模写能力(shapes copying ability) kn-keyword=図形模写能力(shapes copying ability) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year= dt-pub= dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Artemisia indica Willd. var. maximowiczii (Nakai) H.Hara kn-title=ヨモギ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-keyword=キク科 (Asteraceae) kn-keyword=キク科 (Asteraceae) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year= dt-pub= dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hypericum perforatum L. subsp. chinense N.Robson kn-title=コゴメバオトギリ en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-keyword=オトギリソウ科 (Hypericaceae) kn-keyword=オトギリソウ科 (Hypericaceae) END start-ver=1.4 cd-journal=joma no-vol=129 cd-vols= no-issue=2 article-no= start-page=111 end-page=114 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Adenocarcinoma in the jejunum 20 years after surgery for familial adenomatous polyposis kn-title=家族性大腸腺腫症術後20年後に小腸癌を発症した1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 58-year-old Japanese man visited a local clinic for the evaluation of a stomachache. He was diagnosed with intestinal obstruction. His medical history included a proctocolectomy at the age of 38 years, due to familial adenomatous polyposis (FAP). He was referred to our institution, where he underwent a computed tomography examination and endoscopy of the small intestine. The pathological diagnosis was adenocarcinoma. No invasive or metastatic lesions were observed. Therefore, partial resection of the ileum with lymphadenectomy and reconstruction of the ileostomy were performed. Pathological examination revealed that the tumor was type 2, pT3 (SS) , pN1, pPM0, pDM0, pRM0, INFb, ly1, v1, pEX0, PN0. Twenty-nine days after the surgery, the patient was diagnosed with lung metastasis and he underwent lung radiofrequency ablation. We suggest that long-term follow-up is necessary for patients after surgery for FAP, because of the risk of malignant disease developing in other organs. en-copyright= kn-copyright= en-aut-name=SugiharaYuusaku en-aut-sei=Sugihara en-aut-mei=Yuusaku kn-aut-name=杉原雄策 kn-aut-sei=杉原 kn-aut-mei=雄策 aut-affil-num=1 ORCID= en-aut-name=KawanoSeiji en-aut-sei=Kawano en-aut-mei=Seiji kn-aut-name=川野誠司 kn-aut-sei=川野 kn-aut-mei=誠司 aut-affil-num=2 ORCID= en-aut-name=HaradaKeita en-aut-sei=Harada en-aut-mei=Keita kn-aut-name=原田馨太 kn-aut-sei=原田 kn-aut-mei=馨太 aut-affil-num=3 ORCID= en-aut-name=TakashimaShiho en-aut-sei=Takashima en-aut-mei=Shiho kn-aut-name=高嶋志保 kn-aut-sei=高嶋 kn-aut-mei=志保 aut-affil-num=4 ORCID= en-aut-name=TakeiDaisuke en-aut-sei=Takei en-aut-mei=Daisuke kn-aut-name=竹井大介 kn-aut-sei=竹井 kn-aut-mei=大介 aut-affil-num=5 ORCID= en-aut-name=InokuchiToshihiro en-aut-sei=Inokuchi en-aut-mei=Toshihiro kn-aut-name=井口俊博 kn-aut-sei=井口 kn-aut-mei=俊博 aut-affil-num=6 ORCID= en-aut-name=TakaharaMasahiro en-aut-sei=Takahara en-aut-mei=Masahiro kn-aut-name=高原政宏 kn-aut-sei=高原 kn-aut-mei=政宏 aut-affil-num=7 ORCID= en-aut-name=HiraokaSakiko en-aut-sei=Hiraoka en-aut-mei=Sakiko kn-aut-name=平岡佐規子 kn-aut-sei=平岡 kn-aut-mei=佐規子 aut-affil-num=8 ORCID= en-aut-name=MoriYoshiko en-aut-sei=Mori en-aut-mei=Yoshiko kn-aut-name=母里淑子 kn-aut-sei=母里 kn-aut-mei=淑子 aut-affil-num=9 ORCID= en-aut-name=KishimotoHiroyuki en-aut-sei=Kishimoto en-aut-mei=Hiroyuki kn-aut-name=岸本浩行 kn-aut-sei=岸本 kn-aut-mei=浩行 aut-affil-num=10 ORCID= en-aut-name=NagasakaTakeshi en-aut-sei=Nagasaka en-aut-mei=Takeshi kn-aut-name=永坂岳司 kn-aut-sei=永坂 kn-aut-mei=岳司 aut-affil-num=11 ORCID= en-aut-name=OkadaHiroyuki en-aut-sei=Okada en-aut-mei=Hiroyuki kn-aut-name=岡田裕之 kn-aut-sei=岡田 kn-aut-mei=裕之 aut-affil-num=12 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=3 en-affil=Department of Gastroenterological Surgery, Okayama University Hospital kn-affil=岡山大学病院 光学医療診療部 affil-num=4 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=5 en-affil=Department of Gastroenterological Surgery, Okayama University Hospital kn-affil=岡山大学病院 光学医療診療部 affil-num=6 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=7 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=8 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 affil-num=9 en-affil=Division of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院 消化管外科 affil-num=10 en-affil=Division of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院 消化管外科 affil-num=11 en-affil=Division of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院 消化管外科 affil-num=12 en-affil=Department of Gastroenterology and Hepatology, Okayama University Hospital kn-affil=岡山大学病院 消化器内科 en-keyword=家族性大腸腺腫症 (familial adenomatous polyposis) kn-keyword=家族性大腸腺腫症 (familial adenomatous polyposis) en-keyword=小腸癌 (jejunal cancer) kn-keyword=小腸癌 (jejunal cancer) en-keyword=小腸内視鏡検査 (small intestine endoscope) kn-keyword=小腸内視鏡検査 (small intestine endoscope) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=海藻由来レクチンを用いた口腔バイオフィルム感染症の制御〜有効性と安全性の検討〜 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShiotaYasuyoshi en-aut-sei=Shiota en-aut-mei=Yasuyoshi kn-aut-name=塩田康祥 kn-aut-sei=塩田 kn-aut-mei=康祥 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=3 article-no= start-page=245 end-page=249 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20151201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Drug interaction (34. Drug interactions of food and medicine) kn-title=薬物相互作用 (34―食事と薬の薬物相互作用) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HinoHayato en-aut-sei=Hino en-aut-mei=Hayato kn-aut-name=日野隼人 kn-aut-sei=日野 kn-aut-mei=隼人 aut-affil-num=1 ORCID= en-aut-name=KitamuraYoshihisa en-aut-sei=Kitamura en-aut-mei=Yoshihisa kn-aut-name=北村佳久 kn-aut-sei=北村 kn-aut-mei=佳久 aut-affil-num=2 ORCID= en-aut-name=SendoToshiaki en-aut-sei=Sendo en-aut-mei=Toshiaki kn-aut-name=千堂年昭 kn-aut-sei=千堂 kn-aut-mei=年昭 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 affil-num=2 en-affil= kn-affil=岡山大学病院 affil-num=3 en-affil= kn-affil=岡山大学病院 END start-ver=1.4 cd-journal=joma no-vol=125 cd-vols= no-issue=1 article-no= start-page=35 end-page=39 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An epidemiologically rare case of Vibrio vulnificus infection that occurred in October in an inland city of Japan kn-title=内陸地津山で発症した季節外れのVibrio vulnificus感染症 en-subtitle= kn-subtitle= en-abstract= kn-abstract= A 68-year-old man with alcohol addiction, who lived in the suburbs of Tsuyama, an inland city located in northeast Okayama prefecture, was transported to the emergency unit of the Tsuyama Central Hospital in a state of cardiopulmonary arrest (CPA). Despite rigorous systemic investigation and treatment, the patient died 2 hours after arrival. After his death, Vibrio vulnificus was isolated from his blood culture.  Vibrio vulnificus causes fatal infection in humans, usually only in areas located close to the sea where appropriate temperature and suitable salt concentration for its growth are available. Therefore, its occurrence is epidemiologically restricted ; in Japan, the western coastal areas, especially in summers, are reported to be the high-risk regions. This is a rare case because it occurred in a city approximately 50 kilometers from both the Sea of Japan and the Pacific coast of Okayama, and at the end of October in 2011. Economic development and distribution systems have made it possible to transport various food products from coastal areas or abroad to any place in a short time, such that these infections can potentially develop in areas other than expected. We should be aware of the increasing risk of Vibrio vulnificus infection during any season and at any place, especially in patients with abnormal liver function. en-copyright= kn-copyright= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name=萩谷英大 kn-aut-sei=萩谷 kn-aut-mei=英大 aut-affil-num=1 ORCID= en-aut-name=ShiotaSumiko en-aut-sei=Shiota en-aut-mei=Sumiko kn-aut-name=塩田澄子 kn-aut-sei=塩田 kn-aut-mei=澄子 aut-affil-num=2 ORCID= en-aut-name=MiyoshiShin-ichi en-aut-sei=Miyoshi en-aut-mei=Shin-ichi kn-aut-name=三好伸一 kn-aut-sei=三好 kn-aut-mei=伸一 aut-affil-num=3 ORCID= en-aut-name=KuroeYasutoshi en-aut-sei=Kuroe en-aut-mei=Yasutoshi kn-aut-name=黒江泰利 kn-aut-sei=黒江 kn-aut-mei=泰利 aut-affil-num=4 ORCID= en-aut-name=NojimaHiroyoshi en-aut-sei=Nojima en-aut-mei=Hiroyoshi kn-aut-name=野島宏悦 kn-aut-sei=野島 kn-aut-mei=宏悦 aut-affil-num=5 ORCID= en-aut-name=OtaniShinkichi en-aut-sei=Otani en-aut-mei=Shinkichi kn-aut-name=大谷晋吉 kn-aut-sei=大谷 kn-aut-mei=晋吉 aut-affil-num=6 ORCID= en-aut-name=SugiyamaJunichi en-aut-sei=Sugiyama en-aut-mei=Junichi kn-aut-name=杉山淳一 kn-aut-sei=杉山 kn-aut-mei=淳一 aut-affil-num=7 ORCID= en-aut-name=NaitoHiromichi en-aut-sei=Naito en-aut-mei=Hiromichi kn-aut-name=内藤宏道 kn-aut-sei=内藤 kn-aut-mei=宏道 aut-affil-num=8 ORCID= en-aut-name=KawanishiSusumu en-aut-sei=Kawanishi en-aut-mei=Susumu kn-aut-name=川西進 kn-aut-sei=川西 kn-aut-mei=進 aut-affil-num=9 ORCID= en-aut-name=HagiokaShingo en-aut-sei=Hagioka en-aut-mei=Shingo kn-aut-name=萩岡信吾 kn-aut-sei=萩岡 kn-aut-mei=信吾 aut-affil-num=10 ORCID= en-aut-name=MorimotoNaoki en-aut-sei=Morimoto en-aut-mei=Naoki kn-aut-name=森本直樹 kn-aut-sei=森本 kn-aut-mei=直樹 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=2 en-affil= kn-affil=就実大学薬学部 病原微生物学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 衛生微生物化学 affil-num=4 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=5 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=6 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=7 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=8 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=9 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=10 en-affil= kn-affil=津山中央病院 救命救急センター affil-num=11 en-affil= kn-affil=津山中央病院 救命救急センター en-keyword=Vibrio vulnificus kn-keyword=Vibrio vulnificus END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=6 article-no= start-page=1227 end-page=1248 dt-received= dt-revised= dt-accepted= dt-pub-year=1955 dt-pub=19550630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Plasma Proteins of Patients with Gastric Cancer and the Effect of Operation them III. Circulating Blood Volume, Circulating Plasma Volume, Circulating Cell Volume, Total Circulating Plasma Protein Mass and Total Circulating Hemoglobin Mass in Patients with Gastric Cancer kn-title=胃癌患者の血漿蛋白並びに之に及ぼす手術の影響について 第III編 胃癌患者の循環血液量,同血漿量,同血球量,循環血漿蛋白量,同ヘモグロビン量並びに之に及ぼす手術の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The data presented in the second paper indicated that in Patients with gastric cancer the preoperative determinations of albumin content and albuminglobulin ratio were of value for judging the patient's condition of nutrition and operative prognosis, but that the alternation occurring in the concentrations of plasma protein fractions following operation was not always proportional to the preoperative degree of protein deficiency and the clinical picture. Therefore this paper is concerned with the study on hypoproteinemia in patients with gastric cancer on the base of the examination of both the concentration and the total circulating mass of plasma protein. Blood volume, plasma volume, cell volume, total circulating plasma protein mass, total circulating hemoglobin mass, plasma protein contration and hemoglobin concentration in 14 patients with gastric cancer were measured before and after operation. As control material similar studies were made in 11 normal persons, in 13 patients with gastroduodenal ulcer, in 5 cases of cancer of the brest and in 4 cases of Graves' disease. Additional studies were done to determine a standard of blood requirement to be transfused by investigating the effect of transion in the cases in which blnod had been administered before and after operation. The resnlts of these studies were as follows: 1. In patients with gastric cancer there was a decrease in blood volume and in cell volume. 2. Plasma volume was above normal in many patients with gastric cancer and decreased in only a few cases. 3. The decreased blood volume in patients with gastric cancer chiefly was due to a reduction of cell volume, and there were a few cases where plasma volume was concerned in it. 4. The prognosis of the patients with gastric cancer who had a decreased blood volume was poor. 5. In patients with gastric cancer a decrease of both total circulating hemoglobin mass was noted, the loss of the later being more pronounced. 6. In patients with gastric cancer the transfusion of at least 1000 cc each of whole blood and plasma was considered necessary before operation. 7. In patients with gastric cancer blood volume, plasma volune and cell volume were reduced 4 to 8 days after the resection of the stomach. After the 12th postoperative day, plasma volume increased, whereas cell volume did little. 8. Total circulating plasma protein mass in patients with gastric cancer decreased 4 to 8 days after operation, but increased after the 12th postoperative day. 9. Total circulating hemoglobin mass in patientients with gastric cancer.was markedly decreased following resection of the stomach. The value showed a especially sharp decrease on the 4th postoperative day and still further decreased gradually afterwards and there were a few cases in which it shifted to the increase on discharge from the hospital. 10. There were the cases of gastric cancer where a discrepancy between the concentration and the total circulating mass of blasma protein was noted and this tendency was more striking in both of hemoglobin. It was often difficult, therefore, to estimate total circulating mass of plasma protein and hemoglobin by the determination of only concentration of plasma protein and hemoglobin. 11. Total plasma protein mass rather than total total hemoglbin mass was suitable as an index of tissue protein deficiency in the postoperative course of patients with gastric cancer. 12. The variations in values of blood determined after operation in patiens with gastric cancer depended on the preoperative state of body nutrition and on the amount of blood postoperatively transfused. In well nourished patients and in those transfused over 800cc of blood, the degree of reduction in blood volume aud plasma volume was low, and on discharge from the hospital, there was a tendency for total circulating plasma protein mass to increase above the preoperative value. en-copyright= kn-copyright= en-aut-name=ShiotaBenjiro en-aut-sei=Shiota en-aut-mei=Benjiro kn-aut-name=塩田弁治郎 kn-aut-sei=塩田 kn-aut-mei=弁治郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=6 article-no= start-page=1209 end-page=1226 dt-received= dt-revised= dt-accepted= dt-pub-year=1955 dt-pub=19550630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Plasma Proteins of Patients with Gastric Cancer and the Effect of Operation them II. Plasma Protein Fractions in Patients with Gastric Cancer and the Efiect of Operatlon on them kn-title=胃癌患者の血漿蛋白並びに之に及ぼす手術の影響について 第II編 胃癌患者の血漿蛋白分劃並びに之に及ぼす手術の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The data presented in the first paper demonstrated that patients with gastric cancer suffered from a significant decrease in plasma proteins concentration on admission to the hospital, but that the postoperative course was frequently associated with a increased plasma protein content. It is the purpose of this paper to discuss these findings by the determination of plasma protein fractions. The pre- and post-operative concentrations of plasma protein protein fractions in 47 patients with gastric cancer were measured by refractometry and electrophoresis. As control material 15 normal individuals including mild patients near normal, 13 cases of rectal cancer, 13 cases of various types of cancer other than that of the alimentary tract, 9 cases of sarcoma and 29 patients with gastroduodenal ulcer-a total of 90 cases-were selected. The following results were obtained: 1. Patients with gastric cancer showed a marked decrease of albumin fraction. This is the cause of the hypoproteinemia in these patients. 2. The decreased albumin concentration in patients with gastric cancr was noted to become more profound with the progress of the disease. 3. The reduction of albumin content in patients with gastric cancer was more pronounced in the cases where the passageway of the stomach was not patent than in those where it was patent. 4. In patients with gastric cancer an increase of both globulin and fibrinogen fraction was demonstrated. 5. With the occurrence of metastasis of gastric cancer in the liver, there was found an increase in β- and γ-globulins. 6. Albumin-globulin ratio in patients with gastric cancer was lowered and became lower with the progress of the disease. 7. The albumin level and the albumin-globulin ratio in patients with gastric cancer proved to be the index of the prognosis, and albumin levels below 2.70g/dl and albumin-globnlin ratio under 1.0 were associated with an increased incidence of the cases where radical operation was not indicated and of postoperative complications. 8. The determination of plasma protein fractions was of little significance in the differential diagnosis between gastric cancer and gastroduodenal ulcer. 9. The albumin concentrations in patients with gastric cancer decreased after gastric resection. The degree of the decrease was more profound in the cases where preoperative levels of albumin were higher. On discharge from the hospital the albumin contents were, in most cases, found to increase over those before operation. 10. An increase in both fibrinogen and globulin fractions occurred after gastric resection for cancer. On discharge from the hospital these levels, although lowered, yet remained slightly higher than those before operation. en-copyright= kn-copyright= en-aut-name=ShiotaBenjiro en-aut-sei=Shiota en-aut-mei=Benjiro kn-aut-name=塩田弁治郎 kn-aut-sei=塩田 kn-aut-mei=弁治郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue=6 article-no= start-page=1195 end-page=1207 dt-received= dt-revised= dt-accepted= dt-pub-year=1955 dt-pub=19550630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Plasma Proteins of Patients with Gastric Cancer and the Effect of Operation them I. Plasma Protein Concentrations in Patients with Gastric Cancer and the Effect of Operation on them kn-title=胃癌患者の血漿蛋白並びに之に及ぼす手術の影響について 第1編 胃癌患者の血漿蛋白並びに之に及ぼす手術の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Patients with gastric cancer today coming under the care of surgeon often considerably malnourished. Because of a high incidence of postoperative complications and deaths in these patients, a study was instituted to investigate the state of their plasma proteins. This paper deals with the plasma protein concentrations in patients with gastic cancer, the effect of operation on them and the significance of plasma protein determination in therapy and as a prognostic aid. The concentrations of plasma protein in 43 patients with gastric cancer were pre- and post-operatively measured by copper sulfate specific gravity method, and 10 normal persons and 26 patients with gastroduodenal ulcer were studied as the control. The results obtained were as follows: 1. A significant decrease in the preoperative concentrations of plasma protein was observed in patients with gastric cancer. 2. Whether radical operation could be performed or not, and whether the gastric passageway was patent or not, made no difference in the plasma protein levels of patients with gastric cancer. 3. The determination of plasma protein was of little significance in the differential diagnosis between gastric cancer and gastroduodenal ulcer except in special cases. In the absence of massive hemorrhage or severe obstruction, plasma protein concentrations below 6.5 g/dl had some significance, those below 6.0 g/dl having a important significance. 4. The lowest level of plasma protein concentration in the patients who overcame a partial gastrectomy for gastric cancer was 4.72 g/dl. 5. Following resection of the stomach for gastric cancer, it was in most cases found that a decrease in plasma protein concentration occurred in the patients having the preoperative level abov 6.5 g/dl, whereas an increase occurred in those showing a level lower than 6.5 g/dl before operation. 6. The most pronounced drop in plasma protein concentration occurred about 7 to 12 days after gastric resection for cancer of the stomach. 7. Most of the patients with gastric cancer who underwent merely exploratory laparotomy or gastrojejunostomy because radical operation was impossible to be performed, showed a increased concentration of plasma protein after operation. 8. Death following operation for gastric cancer was found to occur in the patients who had low levels of plasma protein concentration. en-copyright= kn-copyright= en-aut-name=ShiotaBenjiro en-aut-sei=Shiota en-aut-mei=Benjiro kn-aut-name=塩田弁治郎 kn-aut-sei=塩田 kn-aut-mei=弁治郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=5 article-no= start-page=1367 end-page=1377 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental and Clinical Studies on the Injection Treatment of Hemorrhoid Part III: Clinical Study kn-title=痔核内注射療法に関する基礎的並びに臨床的研究 第3編 臨床的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author has carried out clinical experiment by injecting Antihemorrhoid into hemorrhoidal node. 1) In 5% solution the hemorrhoidal node became atrophied and disappeared in short period without after-treatment. 2) In 15% solution some of the cases showed atrophies but most of them necroses. Ointment application as after-treatment was needed because of the ulceration after its falling off. 3) In 25% solution extensive necrosis was observed and needed a long termed after-treatment for the ulcer followed by its falling off. 4) There were no noticeable complications by the injection. By the results obtained above, the author concludes that this medical treatment for hemorrhoid is as effective as the radical operation, if one would select cases for this treatment with caution, and that Antihemorrhoid is an ideal medicament; 5% solution for the sclerosing, and 15% or 25% for the corrosion therapy. en-copyright= kn-copyright= en-aut-name=ShiotaKinei en-aut-sei=Shiota en-aut-mei=Kinei kn-aut-name=塩田欣栄 kn-aut-sei=塩田 kn-aut-mei=欣栄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=5 article-no= start-page=1355 end-page=1366 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental and Clinical Studies on the Injection Treatment of Hemorrhoid Part II: Influences of Antihemorrhoid on the Clotting Time and on the Thrombosis kn-title=痔核内注射療法に関する基礎的並びに臨床的研究 第2編 Antihemorrhoid溶液の凝血時間並びに血栓形成に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author has observed the influences of Antihemorrhoid on the clotting time under its direct action in rabbit's blood, and on the process of thrombosis pathologically, after injecting the drug into V. jugularis externa ligated doubly. 1) In the small dosis resulted a slight reduction of clotting time but it was prolonged with the increase in amount. 2) Thrombosis was observed 24 hours after the injection. In 5 and 15% solutions chemical inflammations were slight and completely organized on the 15th day after subsidence of the inflammations. However, in 25% solution produced necrosis not following by organiztion. 3) In the control group thrombosis was observed on the 5th day but inflammatory process was slight, following by minimal organization on the 15th day. The author concludes that this drug plays more important role on the thrombosis than on the blood clotting. en-copyright= kn-copyright= en-aut-name=ShiotaKinei en-aut-sei=Shiota en-aut-mei=Kinei kn-aut-name=塩田欣栄 kn-aut-sei=塩田 kn-aut-mei=欣栄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部津田外科教室 END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue= article-no= start-page=51 end-page=55 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases kn-title=気管支喘息における運動浴前後のventilatory functionの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1. en-copyright= kn-copyright= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=1 ORCID= en-aut-name=KomagoeHaruki en-aut-sei=Komagoe en-aut-mei=Haruki kn-aut-name=駒越春樹 kn-aut-sei=駒越 kn-aut-mei=春樹 aut-affil-num=2 ORCID= en-aut-name=MurashimaMakoto en-aut-sei=Murashima en-aut-mei=Makoto kn-aut-name=村嶋誠 kn-aut-sei=村嶋 kn-aut-mei=誠 aut-affil-num=3 ORCID= en-aut-name=OkadaChiharu en-aut-sei=Okada en-aut-mei=Chiharu kn-aut-name=岡田千春 kn-aut-sei=岡田 kn-aut-mei=千春 aut-affil-num=4 ORCID= en-aut-name=TanisakiYoshiro en-aut-sei=Tanisaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=5 ORCID= en-aut-name=MorinagaHiroshi en-aut-sei=Morinaga en-aut-mei=Hiroshi kn-aut-name=森永寛 kn-aut-sei=森永 kn-aut-mei=寛 aut-affil-num=6 ORCID= en-aut-name=ShiotaYutaro en-aut-sei=Shiota en-aut-mei=Yutaro kn-aut-name=塩田雄太郎 kn-aut-sei=塩田 kn-aut-mei=雄太郎 aut-affil-num=7 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=7 en-affil= kn-affil=岡山大学医学部第二内科 affil-num=8 en-affil= kn-affil=岡山大学医学部第二内科 END start-ver=1.4 cd-journal=joma no-vol=29 cd-vols= no-issue= article-no= start-page=(199) end-page=(203) dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100326 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Selective Attention Toward the Self-Name : Exploration with an Oddball Task kn-title=自己の名前と選択的注意:オドボール課題による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShiotaMayuko en-aut-sei=Shiota en-aut-mei=Mayuko kn-aut-name=塩田真友子 kn-aut-sei=塩田 kn-aut-mei=真友子 aut-affil-num=1 ORCID= en-aut-name=HatanakaNanase en-aut-sei=Hatanaka en-aut-mei=Nanase kn-aut-name=畠中七瀬 kn-aut-sei=畠中 kn-aut-mei=七瀬 aut-affil-num=2 ORCID= en-aut-name=HoriuchiTakashi en-aut-sei=Horiuchi en-aut-mei=Takashi kn-aut-name=堀内孝 kn-aut-sei=堀内 kn-aut-mei=孝 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=1 article-no= start-page=43 end-page=54 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship between the accreditation criteria for disability pensions and work status : Focusing on mental disorders and mental retardation kn-title=障害年金の認定基準と就労の関係―精神障害・知的障害を中心として en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study aims to examine whether work status is the only basis for determining the provision of disability pensions in cases of mental illness, and considers the validity of this criterion and ways to improve the system. We collected 178 decisions of the Examination Committee of Social Insurance due to "Mental Illness" over a period of 11 years (1994 to 2004), and investigated the relationships among three factors : activity of daily living (ADL), work status, and pension benefits. We also examined the 21 working subjects separately. We found a significant relationship between ADL and pension benefits and between work status and pension benefits. No significant relationship was found between ADL and work status. In 6 of the 21 working subjects, the disability pension decision was made solely by focusing on work status. Despite this focus on work status, the working disabled cannot always compensate for their reduced income and the extraordinary expenditure incurred due to their disability. Further, because these decisions can go against the trend of encouraging the disabled to work, we suggest that it is not appropriate to focus solely on work status in determining pension benefits and propose ways to improve the system. en-copyright= kn-copyright= en-aut-name=KoumotoJunko en-aut-sei=Koumoto en-aut-mei=Junko kn-aut-name=河本純子 kn-aut-sei=河本 kn-aut-mei=純子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 疫学・衛生学分野 en-keyword=精神障害 (mental disorder) kn-keyword=精神障害 (mental disorder) en-keyword=知的障害 (mental retardation) kn-keyword=知的障害 (mental retardation) en-keyword=障害年金 (disability pension) kn-keyword=障害年金 (disability pension) en-keyword=社会参加 (social participation) kn-keyword=社会参加 (social participation) en-keyword=公的年金制度 (national pension plan) kn-keyword=公的年金制度 (national pension plan) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=自己と他者の顔および名前の認知プロセスの差異に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShiotaMayuko en-aut-sei=Shiota en-aut-mei=Mayuko kn-aut-name=塩田真友子 kn-aut-sei=塩田 kn-aut-mei=真友子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=7-8 article-no= start-page=653 end-page=665 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation of extracorporeal circulation without donor blood priming in the pump oxygenator: With a special reference to oxygen delivery and hemodynamics. kn-title=無血充塡体外循環法の検討 ―とくに酸素運搬能と血行動態について― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Extracorporeal circulation (ECC) without donor blood priming in the pump oxygenator was applied in 23 cases, of which 16 cases needed no blood transfusion (Group Ia) and 7 cases required blood transfusion because of peri-and/or postoperative bleeding (Group Ib). In these two groups, hemodynamic study, blood gas study and chemical determinations were carried out during and after ECC and postoperatively for the initial three days, comparing the results with ten cases (Group Ⅱ) of usual ECC with 20% hemodilution. The results were as follows: 1) The hematocrit value and hemoglobin level of Group Ia and Ib were significantly lower than those of Group Ⅱ during ECC, but recovered to the same level as Group Ⅱ four hours after ECC, and all blood in the pump oxygenator returned. 2) The parameters of hemodynamics, cardiac index (CI), stroke index (SI) and total peripheral vascular resistance (TPR), changed in a similar pattern post-operatively in Group Ia and Ⅱ, whereas in Group Ib, CI and SI were markedly depressed during the first postoperative day but recovered by blood transfusion. 3) Oxygen transport, oxygen consumption and oxygen extraction ratio showed no significant differences among the three groups from four hours through three days postoperatively. 4) No remarkable differences of erythrocyte 2, 3 diphosphoglycerate (2, 3 DPG) and P(50) in vivo were observed during ECC through three days postoperatively in all groups, proving that no hypoxemic state occurred during the period. 5) It was revealed that 2, 3 DPG had statistic linear correlation with P(50) in vivo, oxygen transport, CI and venous oxygen content. These facts were thought to occur as a result of a physiological compensatory mechanism for increasing oxygen delivery. 6) Serum LDH increased markedly at the first postoperative day and remained at a high level even seven days after in all groups. In Group Ia and Group Ⅱ, LDH isozyme 1+2/total increased from the second postoprative day, but LDH isozyme 5/total was slightly elevated as early as during ECC, though at the first postoperative day this fraction recovered to the preoperative level. In Group Ib, LDH isozyme 5/total was observed elevating markedly from four hours after ECC, while LDH isozyme 1+2/total decreased remarkably from the same time, but recovered to the normal range at the first postoperative day. It was thought that peripheral circulatory failure would persist and be improved by blood transfusion. It was concluded that ECC without donor blood prime was secure as the usual ECC with 20% hemodilution from the view points of hemodynamics, blood gas analysis, oxygen delivery and chemical determination. There were many advantages such as saving donor blood and relief of various complications of blood transfusion, when the hematocrit value must be kept above 20%. en-copyright= kn-copyright= en-aut-name=ShiotaKunihiko en-aut-sei=Shiota en-aut-mei=Kunihiko kn-aut-name=塩田邦彦 kn-aut-sei=塩田 kn-aut-mei=邦彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第2外科教室 en-keyword=無血充塡体外循環 kn-keyword=無血充塡体外循環 en-keyword=2・3 DPGP kn-keyword=2・3 DPGP en-keyword=P(50) in vivo kn-keyword=P(50) in vivo en-keyword=心機能 kn-keyword=心機能 en-keyword=LDH isozyme kn-keyword=LDH isozyme END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=11-12 article-no= start-page=969 end-page=976 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19811230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Imported malaria in Okayama prefecture kn-title=岡山県における輸入マラリアについて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Two cases of imported malaria which occurred in Okayama prefecture are reported. One was infected with Plasmodium vivax in India, the other with P. falciparum at Nigeria, Africa. The efficacy of some antimalarial drugs in these cases is discussed. One patient was infected with P. falciparum, despite taking the medicine Daraprim® regularly. The efficacy of Daraprim® for suppressive cure in Nigeria is doutful. The therapy of chloroquine-resistance tropical malaria is also discussed. en-copyright= kn-copyright= en-aut-name=AjiToshiki en-aut-sei=Aji en-aut-mei=Toshiki kn-aut-name=安治敏樹 kn-aut-sei=安治 kn-aut-mei=敏樹 aut-affil-num=1 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=2 ORCID= en-aut-name=LaiJim Shung en-aut-sei=Lai en-aut-mei=Jim Shung kn-aut-name=頼俊雄 kn-aut-sei=頼 kn-aut-mei=俊雄 aut-affil-num=3 ORCID= en-aut-name=ShingHo Li en-aut-sei=Shing en-aut-mei=Ho Li kn-aut-name=何黎星 kn-aut-sei=何 kn-aut-mei=黎星 aut-affil-num=4 ORCID= en-aut-name=ShimonoKunio en-aut-sei=Shimono en-aut-mei=Kunio kn-aut-name=下野國夫 kn-aut-sei=下野 kn-aut-mei=國夫 aut-affil-num=5 ORCID= en-aut-name=InatomiSeiichi en-aut-sei=Inatomi en-aut-mei=Seiichi kn-aut-name=稲臣成一 kn-aut-sei=稲臣 kn-aut-mei=成一 aut-affil-num=6 ORCID= en-aut-name=SuguriSetsuo en-aut-sei=Suguri en-aut-mei=Setsuo kn-aut-name=村主節雄 kn-aut-sei=村主 kn-aut-mei=節雄 aut-affil-num=7 ORCID= en-aut-name=ShiotaTetsuya en-aut-sei=Shiota en-aut-mei=Tetsuya kn-aut-name=塩田哲也 kn-aut-sei=塩田 kn-aut-mei=哲也 aut-affil-num=8 ORCID= en-aut-name=SakuraiKoichi en-aut-sei=Sakurai en-aut-mei=Koichi kn-aut-name=桜井浩一 kn-aut-sei=桜井 kn-aut-mei=浩一 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=7 en-affil= kn-affil=香川医科大学病理学講座医動物 affil-num=8 en-affil= kn-affil=岡山大学医学部第1内科教室 affil-num=9 en-affil= kn-affil=岡山協立病院 en-keyword=Imported malaria kn-keyword=Imported malaria en-keyword=Plasmodium vivax kn-keyword=Plasmodium vivax en-keyword=Plasmodium falciparum kn-keyword=Plasmodium falciparum en-keyword=Suppressive cure kn-keyword=Suppressive cure END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=11-12 article-no= start-page=1341 end-page=1345 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19831230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical assessment of prognosis in patients with fulminant hepatitis kn-title=劇症肝炎の予後判別の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Assessment of the prognosis of fulminant hepatitis was made from clinical findings at the time of the appearance of hepatic encephalopathy using five living and ten fatal cases of fulminant hepatitis. Those patients who died tended to be old, especially in the subacute type of fulminant hepatitis, and frequently had disseminated intravascular coagulation. Prognosis scoring by assessing clinical findings in these patients was calculated during their clinical courses. From differences in scores, the treatment performed following the occurrence of hepatic encephalopathy was judged to be effective in some of the surviving patients. Other patients died, however, because of the difficulty of sufficiently controlling complications. The prognosis scoring at the time of the appearance of encephalopathy was valid for female patients who survived. Clinical evaluation of this scoring method will be further evaluated with more cases in the future. en-copyright= kn-copyright= en-aut-name=FujiwaraMasachika en-aut-sei=Fujiwara en-aut-mei=Masachika kn-aut-name=藤原雅親 kn-aut-sei=藤原 kn-aut-mei=雅親 aut-affil-num=1 ORCID= en-aut-name=WatanabeAkiharu en-aut-sei=Watanabe en-aut-mei=Akiharu kn-aut-name=渡辺明治 kn-aut-sei=渡辺 kn-aut-mei=明治 aut-affil-num=2 ORCID= en-aut-name=NakatsukasaHarushige en-aut-sei=Nakatsukasa en-aut-mei=Harushige kn-aut-name=中務治重 kn-aut-sei=中務 kn-aut-mei=治重 aut-affil-num=3 ORCID= en-aut-name=ShiotaTetsuya en-aut-sei=Shiota en-aut-mei=Tetsuya kn-aut-name=塩田哲也 kn-aut-sei=塩田 kn-aut-mei=哲也 aut-affil-num=4 ORCID= en-aut-name=SakataTatsuro en-aut-sei=Sakata en-aut-mei=Tatsuro kn-aut-name=坂田達朗 kn-aut-sei=坂田 kn-aut-mei=達朗 aut-affil-num=5 ORCID= en-aut-name=TakeiNobuyuki en-aut-sei=Takei en-aut-mei=Nobuyuki kn-aut-name=竹井信行 kn-aut-sei=竹井 kn-aut-mei=信行 aut-affil-num=6 ORCID= en-aut-name=KobayashiMichio en-aut-sei=Kobayashi en-aut-mei=Michio kn-aut-name=小林道男 kn-aut-sei=小林 kn-aut-mei=道男 aut-affil-num=7 ORCID= en-aut-name=NagashimaHideo en-aut-sei=Nagashima en-aut-mei=Hideo kn-aut-name=長島秀夫 kn-aut-sei=長島 kn-aut-mei=秀夫 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一内科教室 en-keyword=劇症肝炎 kn-keyword=劇症肝炎 en-keyword=予後 kn-keyword=予後 en-keyword=予後判別スコア kn-keyword=予後判別スコア END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=11-12 article-no= start-page=1153 end-page=1158 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19831230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Correlation between cellular components and infiltrating cells in the lung tissue of asthmatics kn-title=気管支喘息におけるBALF中出現細胞と組織出現細胞との比較 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Cell components in the peripheral lung area were examined in 24 asthmatic subjects by bronchoalveolar lavage (BAL) and transbronchoscopic lung biopsy (TBLB). In cases with increased percentage of lymphocytes in bronchoalveolar lavage fluid (BALF), the infiltration of eosinophils and mononuclear cells in the peripheral lung tissue was observed with a high frequency. The increased percentage of eosinophils in BALF correlated with the infiltration of eosinophils and neutrophils in the bronchiolo-alveolar region. A reverse correlation was observed between the macrophage count in the alveolar region and the percentage of eosinophils and lymphocytes in BALF. No significant correlation was present between the percentage of neutrophils in BALF and the infiltration of any type of cell in the lung tissue. en-copyright= kn-copyright= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=1 ORCID= en-aut-name=SudoMichiyasu en-aut-sei=Sudo en-aut-mei=Michiyasu kn-aut-name=周藤真康 kn-aut-sei=周藤 kn-aut-mei=真康 aut-affil-num=2 ORCID= en-aut-name=KobashiHidetoshi en-aut-sei=Kobashi en-aut-mei=Hidetoshi kn-aut-name=小橋秀敏 kn-aut-sei=小橋 kn-aut-mei=秀敏 aut-affil-num=3 ORCID= en-aut-name=ShiodaYutaro en-aut-sei=Shioda en-aut-mei=Yutaro kn-aut-name=塩田雄太郎 kn-aut-sei=塩田 kn-aut-mei=雄太郎 aut-affil-num=4 ORCID= en-aut-name=MatsukaYoko en-aut-sei=Matsuka en-aut-mei=Yoko kn-aut-name=松香陽子 kn-aut-sei=松香 kn-aut-mei=陽子 aut-affil-num=5 ORCID= en-aut-name=TakeyamaHiroyasu en-aut-sei=Takeyama en-aut-mei=Hiroyasu kn-aut-name=竹山博泰 kn-aut-sei=竹山 kn-aut-mei=博泰 aut-affil-num=6 ORCID= en-aut-name=HaradaHiroshi en-aut-sei=Harada en-aut-mei=Hiroshi kn-aut-name=原田寛 kn-aut-sei=原田 kn-aut-mei=寛 aut-affil-num=7 ORCID= en-aut-name=TadaShinya en-aut-sei=Tada en-aut-mei=Shinya kn-aut-name=多田慎也 kn-aut-sei=多田 kn-aut-mei=慎也 aut-affil-num=8 ORCID= en-aut-name=KimuraIkuro en-aut-sei=Kimura en-aut-mei=Ikuro kn-aut-name=木村郁郎 kn-aut-sei=木村 kn-aut-mei=郁郎 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第2内科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第2内科学教室 en-keyword=BAL kn-keyword=BAL en-keyword=TBLB kn-keyword=TBLB en-keyword=リンパ球 kn-keyword=リンパ球 en-keyword=好酸球 kn-keyword=好酸球 END start-ver=1.4 cd-journal=joma no-vol=27 cd-vols= no-issue=1 article-no= start-page=95 end-page=101 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090326 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Are the Processes of Recognizing One's Own Face and Name Special? : Investigation Based on the Stroop Task. kn-title=自分の顔と名前に関する処理は特殊なのか?―ストループ課題に基づいた検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShiotaMayuko en-aut-sei=Shiota en-aut-mei=Mayuko kn-aut-name=塩田真友子 kn-aut-sei=塩田 kn-aut-mei=真友子 aut-affil-num=1 ORCID= en-aut-name=HoriuchiTakashi en-aut-sei=Horiuchi en-aut-mei=Takashi kn-aut-name=堀内孝 kn-aut-sei=堀内 kn-aut-mei=孝 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=387 end-page=397 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lymphocyte function bronchial asthma Part 1. Examination of lymphocyte responsiveness with inhalation antigens of bronchial asthma kn-title=気管支喘息におけるリンパ球機能に関する研究 第1編 気管支喘息におけるBAL 液中並びに末梢血中リンパ球の吸入抗原に対する幼若化反応の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Various antigens such as mite and fungi have been known to provoke bronchoconstriction in patients with bronchial asthma. The allergic mechanisms of asthmatic attack induced by these antigens were analyzed to clarify the role of cellular immunity in the pathogenesis of bronchial asthma. Mite and Candida antigens were applied to lymphocyte blastogenesis in asthmatic patients. Both lymphocytes in bronchoalveolar lavage fluid (BALF) and in peripheral blood of asthmatic patients responded significantly to mite and Candida antiten. Furthermore, BALF lymphocytes of patients with non-atopic and intractable asthma showed higher responses against Candida antigen than those of patients with atopic and non-intractable asthma, while peripheral blood lymphocytes showed a higher response against mite antigen in patients with atopic and non-intractable asthma. These findings indicate that lymphocytes in lugns sensitized with Candida antigen might play an important role in the pathogenesis of non-atopic and intractable asthma. en-copyright= kn-copyright= en-aut-name=TakadaSho en-aut-sei=Takada en-aut-mei=Sho kn-aut-name=武田昌 kn-aut-sei=武田 kn-aut-mei=昌 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=リンパ球幼若化反応 kn-keyword=リンパ球幼若化反応 en-keyword=bronchoalveolar lavage kn-keyword=bronchoalveolar lavage en-keyword=Candida kn-keyword=Candida en-keyword=mite kn-keyword=mite END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=1-2 article-no= start-page=1 end-page=9 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical significance of Creola body in the sputum of bronchial asthmatics kn-title=気管支喘息における喀痰中の Creola body に関する研究 第1編 気管支喘息患者喀痰中における Creola body の臨床的意義についての検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To examine the clinicopathology of agglomerated bronchial epithelial cells, i. e. Creola body (CrB), in the sputum, the incidence of CrB stained by Papanicoloaou's method was evaluated in 46 bronchial asthmatics and 10 patients with obstructive pulmonary diseases, and then was compared with the pathogenetic factors of bronchial asthma. CrB was observed specifically in the sputum of bronchial asthmatics. CrB-positive cases had asthma attacks for more than 4 days and a high incidence of eosinophils in the sputum, but not CrB-negative cases. The presence of CrB in the sputum tended to be high in non-atopic asthmatics with a low serum IgE level, but had no significant correlation with either the incidence of neutrophils in the sputum, the present age of patients, the severity of the disease or bronchial hyperresponsiveness to acetylcholine. These findines suggest that the involvement of histolesional factors such as persistent bronchial contraction and release of major basic protein from eosinophils in the airway may lead to the formation of CrB. Also the appearance of CrB may be a useful index for pre-serious stage of asthma. en-copyright= kn-copyright= en-aut-name=IsoshimaKoji en-aut-sei=Isoshima en-aut-mei=Koji kn-aut-name=磯嶋浩二 kn-aut-sei=磯嶋 kn-aut-mei=浩二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=bronchial asthma kn-keyword=bronchial asthma en-keyword=sputum kn-keyword=sputum en-keyword=Creola body kn-keyword=Creola body en-keyword=eosinophil kn-keyword=eosinophil en-keyword=neutrophil kn-keyword=neutrophil END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=5-6 article-no= start-page=561 end-page=571 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on inhalation provocatopn test of Candida antigen in bronchial asthma kn-title=気管支喘息におけるカンジダ抗原吸入誘発試験の臨床的検討―遅延型気道反応を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Various allergic mechanisma participate in the reversible bronchospasms of an asthma attack. Candida albicans was suspected as the causative antigen in late-onset and severe intractable asthma. In this study, inhalation provocation test was performed with Candida antigen to evaluate the asthmatic responses of asthmatic patients with positive skin reaction to Candida antigen. More than 20% decrease in park flow after antigen inhalation was considered an asthmatic response and such responses were classified as immediate (IAR), late (LAR) or delayed (DeAR) depending on the time course after antigen inhalation. Provocation tests induced asthmatic responses in 26(42.6%) patients and 11(42.3%) showed DeAR. Eight of the 11 patients with DeARs had late onst asthma and 7 patients had intractable asthma. Furthermore, patients with DeARs showed higher lymphocyte responses to Candida antigen than those with IAR or LAR. These date indicate that EeAR to Canidia antigen plays an important role in the pathogenesis of severe intractable asthma. en-copyright= kn-copyright= en-aut-name=InokiAtsuhiro en-aut-sei=Inoki en-aut-mei=Atsuhiro kn-aut-name=猪木篤弘 kn-aut-sei=猪木 kn-aut-mei=篤弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=難治性喘息 kn-keyword=難治性喘息 en-keyword=カンジダ抗原 kn-keyword=カンジダ抗原 en-keyword=吸入誘発試験 kn-keyword=吸入誘発試験 en-keyword=遅延型気道反応 kn-keyword=遅延型気道反応 en-keyword=リンパ球幼若化反応 kn-keyword=リンパ球幼若化反応 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=3-4 article-no= start-page=341 end-page=351 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the pathogenesis of lung cancer with interstitial pneumonia Part 1. Analysis of the clinical features of intersitial pneumonia in lung cancer kn-title=肺癌のびまん性肺線維化病態に関する研究 第1編 肺癌に随伴するびまん性間質性陰影の臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Clinical features and findings on chest x-ray were analyzed to clarify the relationship between lung cancer and interstitial pneumonia. Of 262 patients with lung cancer, 69 patients (26.3%) had interstitial pneumonia. Patients with interstitial pneumonia (LC with IP) were older than those without interstitial pneumonia (LC without IP). The incidence of LC with IP cases among males and smokers were 29.2% and 29.3%, respectively. There were no significant differences among histlogic types and clinical stages of lung cancer. More cases of LC with IP had cancer in the lower (42.0%) and peripheral (76.8%) areas on chest x-ray films. Cancer was frequently located within the interstitial shadow on chest x-ray film. Among 40 patients with idiopathic interstitial pneumonia associated lung cancer (IIP with LC), there were 38 males and 32 smokers. No dominant histlogic subtype of lung cancer was noted in IIP with LC, though the most frequent was adenocarcinoma (16 cases, 40%). In IIP with LC, the site of cancer was associated with active fibrotic changes in interstitial pneumonia. These data strongly suggest that carcinogenic factors were related to the fibrotic changes in interstitial pneumonia. en-copyright= kn-copyright= en-aut-name=ShibayamaTakuo en-aut-sei=Shibayama en-aut-mei=Takuo kn-aut-name=柴山卓夫 kn-aut-sei=柴山 kn-aut-mei=卓夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=Lung cancer kn-keyword=Lung cancer en-keyword=Idiopathic interstitial pneumonia kn-keyword=Idiopathic interstitial pneumonia en-keyword=Chest X-ray finding kn-keyword=Chest X-ray finding END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=1-2 article-no= start-page=195 end-page=204 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the mechanism of late asthmatic response using a technique of bronchoalveolar lavage Part 2. Bronchial reaction after inhalation of Candida allergen in bronchial asthmatics kn-title=気管支喘息における遅発型気道反応の機序に関する研究 第2編 Candida 抗原による遅発型気道反応局所の細胞反応及びロイコトリエンの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the mechanism of late asthmatic response (LAR) which is related to intractable asthmatic attacks, cellular and humoral components at the sites of LAR were examined by bronchoalveolar lavage fluid (BALF) obtained after bronchial inhalation of Candida allergen. BAL examination was performed 2 hours after the LAR attack. The differential cell count was obtained and the level of leukotrienes (LTs) in the BALF and peripheral blood determined by high performance liquid chromatography. The percentages of eosinophils and basophil・mast cells and neutrophils were statistically high in the BALF after LAR compared with the level in the non-attack state (p<0.05 p<0.01). The level of LTC(4) was significantly higher in the BALF after LAR (p<0.01), and LTB(4) also showed a similar tendency at LAR. However, LTD(4) could not be detected in the BALF after LAR or in the non-attack stage. On the other hands, the percentage of neutorphils and LTB4 level in circulating blood showed a peak before LAR, and then decreased markedly during LAR. Eosinophils also decreased significantly during LAR, but the plasma LTC(4) level increased significantly during LAR. These findings suggest that neutrophils, eosinophils and basophil・mast cells play an important role in the pathogensis of intractable asthma attack and LAR following release of leukotrienes. en-copyright= kn-copyright= en-aut-name=NambaKunihiro en-aut-sei=Namba en-aut-mei=Kunihiro kn-aut-name=難波一弘 kn-aut-sei=難波 kn-aut-mei=一弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=Candida antigen kn-keyword=Candida antigen en-keyword=bronchoalveolar lavage kn-keyword=bronchoalveolar lavage en-keyword=inflammatory cell kn-keyword=inflammatory cell en-keyword=late asthmatic response kn-keyword=late asthmatic response en-keyword=leukotrienes kn-keyword=leukotrienes END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=1-2 article-no= start-page=185 end-page=193 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the mechanism of late asthmatic response using a technique of bronchoalveolar lavage Part 1. Bronchial reaction after inhalation of house dust mite allergen in bronchial asthmatics kn-title=気管支喘息における遅発型気道反応の機序に関する研究 第1編 House dust 抗原による遅発型気道反応局所の細胞反応及びロイコトリエンの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To investigate the mechanism of the late asthmatic response (LAR) which participates in intractable asthmatic attacks, humoral and cellular components at the sites of LAR were examined by bronchoalveolar lavage fluid (BALF) obtained after bronchial inhalation of house dust allergen. BAL examination was performed 2 hours after improvement of LAR, and leukotrienes (LTs) measured by high performance liquid chromatography. The level of LTC4 was significantly higher in BALF after LAR(p<0.05), and that of LTB4 was also high at LAR. The increase in the percentage of neutrophils, eosinophils and basophils were evident in BALF after LAR compared with the level in non-attack state and after IAR. However, little LTD4 was detected in the BALF after LAR. On the other hand, the percentage of neutrophils and the LTB4 level in peripheral blood showed a peak at 3 hours after bronchial inhalation of house dust allergen, and then decreased markedly during LAR. These findings suggest that neutrophils, eosinophils, and basophils may release leukotriene-dominant chemical mediators which provoke an asthmatic attack in the late phase response. en-copyright= kn-copyright= en-aut-name=NambaKunihiro en-aut-sei=Namba en-aut-mei=Kunihiro kn-aut-name=難波一弘 kn-aut-sei=難波 kn-aut-mei=一弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=House dust antigen kn-keyword=House dust antigen en-keyword=bronchoalveolar lavage kn-keyword=bronchoalveolar lavage en-keyword=inflammatory cell kn-keyword=inflammatory cell en-keyword=late asthmatic response kn-keyword=late asthmatic response en-keyword=leukotrienes kn-keyword=leukotrienes END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=1-2 article-no= start-page=71 end-page=81 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the soluble interleukin-2 receptor in patients with bronchial asthma kn-title=気管支喘息におけるInterleukin-2 receptorに関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Cytokine-mediated interactions among blood cells, especially T-lymphoctes, may be impor-tant in the regulation of airway inflammation in asthma. To investigate whether T-lymphocytes are related to disease activity in asthma, serum soluble interleukin-2 receptor (sIL-2R) levels were measured in 77 bronchial asthmatics and 19 healthy volunteers. The serum sIL-2R level was higher in asthmatics than in healthy controls (mean±SD ;449.8±225.5 vs. 323.2±123.9 U/ml ; p<0.01). However, sIL-2R levels were similar between atopic and non-atopic asthmatics (451.9±235.9 vs. 416.7±147.2 U/ml), and were also similar between severe and mild to moderate asthmatics (437.4±209.9 vs. 469.8±276.1 U.ml). Steroid-dependent intractable asthmatics treated with prednisolone st doses of 5-10 mg/day showd higher sIL-2R levels (470.1±257.9 U/ml) than asthmatics treated with the drug at doses below 5 mg/day (357.2±102.6 U/ml) and intractable asthmatics treated with the drug at doses above 10 mg/day (282.5±194.5 U/ml). There was a strong correlation (r=0.915 ; p<0.01) between percentage at IL-2R-positive helper T cells among peripheral white blood cells and the serum concentration of sIL-2R. The type Ⅳ cell-mediated immune response is considered to be related to the pathogenesis of asthman. Serum sIL-2R levels are thought to reflect the extent of T-lymphocyte activation in non-malignant disease, but the level is aiso influenced by steroid therapy. en-copyright= kn-copyright= en-aut-name=KozukaAkiko en-aut-sei=Kozuka en-aut-mei=Akiko kn-aut-name=小塚明子 kn-aut-sei=小塚 kn-aut-mei=明子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=難治性喘息 kn-keyword=難治性喘息 en-keyword=T細胞 kn-keyword=T細胞 en-keyword=IL-2R kn-keyword=IL-2R en-keyword=細胞反応型アレルギー kn-keyword=細胞反応型アレルギー END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=1-2 article-no= start-page=51 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The production of platelet activating factor (PAF) from neutrophils in bronchial asthmatics kn-title=気管支喘息における血小板活性化因子の役割に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It was recently suggested that chemical mediators such as leukotrienes and PAF are more important in the pathogenesis of bronchial asthma than histamine. In this study, to clarify the role of PAF in bronchial asthma, I measured PAF activity derived from human neutrophils by the platelet aggregation tachnique and evaluated this activity in relation to the clinical features of brochial asthma. Neutrophils were separated from heparinized venous blood of 34 bronchial asthmatics and 11 healthy subjects. After suspension at 6×10(6) cells/ml, the cells were treated with 5μg/ml Ca ionophore A23187 for 5 minutes. PAF was extracted from the cell suspension using chloroform, and the activity was measured with an aggregometer using rabbit platelets. PAF activaty was significantly higher (p<0.05) in asthmatics (8.3±6.9 pmol/1×10(6) cells) than in healthy subjects (4.1±3.2 pmol/1×10(6) cells), and tended to increase in steroid-independent asthmatics rather than in steroid-dependent asthma patients. However, there was no difference in PAF production between atopic and non-atopic asthmatics, or between the early and late onset asthmatics. PAF production was increased in patients with severe airway hypersensitivity. These finding suggest that PAF plays an important role in the development and exacerbation of asthma. en-copyright= kn-copyright= en-aut-name=TsujiMitsuaki en-aut-sei=Tsuji en-aut-mei=Mitsuaki kn-aut-name=辻光明 kn-aut-sei=辻 kn-aut-mei=光明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=血小板活性化因子 kn-keyword=血小板活性化因子 en-keyword=好中球 kn-keyword=好中球 END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=1 article-no= start-page=107 end-page=113 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200711 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exaolination of the Cognitive Process of Recognizing One's Own Face Based on the lAC model kn-title=IACモデルに基づいた自己顔の認知過程の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShiotaMayuko en-aut-sei=Shiota en-aut-mei=Mayuko kn-aut-name=塩田真友子 kn-aut-sei=塩田 kn-aut-mei=真友子 aut-affil-num=1 ORCID= en-aut-name=HoriuchiTakashi en-aut-sei=Horiuchi en-aut-mei=Takashi kn-aut-name=堀内孝 kn-aut-sei=堀内 kn-aut-mei=孝 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=3 article-no= start-page=323 end-page=325 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Epigenetics kn-title=エピジェネティクス en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakataKatsuyoshi en-aut-sei=Takata en-aut-mei=Katsuyoshi kn-aut-name=高田尚良 kn-aut-sei=高田 kn-aut-mei=尚良 aut-affil-num=1 ORCID= en-aut-name=YoshinoTadashi en-aut-sei=Yoshino en-aut-mei=Tadashi kn-aut-name=吉野正 kn-aut-sei=吉野 kn-aut-mei=正 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病理・病態学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病理・病態学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=細菌細胞の薬剤耐性系阻害剤の探索とその作用機序 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田澄子 kn-aut-sei=塩田 kn-aut-mei=澄子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=19870930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=人肺胞マクロファージに関する臨床的研究 第1編人肺胞マクロファージの走化能のアガローズ平板法と Boyden Chamber 法による比較 第2編気管支肺胞洗浄法により得られた人肺胞マクロファージの機能 kn-title=Clinical Studies on Human Alveolar Macrophages 第1編 Comparison of Chemotaxis of Human Alveolar Macrophages as Detemined by the Agarose Plate Method and the Boyden Chamber Method 第2編 Functions of Alveolar Macrophages Collected by Bronchoalveolar Lavage en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田雄太郎 kn-aut-sei=塩田 kn-aut-mei=雄太郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=無血充填体外循環法の検討 とくに酸素運搬能と血行動態について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田邦彦 kn-aut-sei=塩田 kn-aut-mei=邦彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19840331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肝性脳症に関する臨床的並びに実験的研究 第1編 定量的 psycho-metric test と潜在性肝性脳症 肝硬変における脳症例と非脳症例の比較研究) 第2編 急性肝不全ラットの脳におけるロイシン脱炭酸活性の増加と血中アンモニア濃度の増加との関連について) kn-title=第1編 Quantitative Psychometric Testing and Subclinical Hepatic Encephalopathy  Comparative Study Between Encephalopathic and Non Encephalopathic Patients with Liver Cirrhosis 第2編 Accelerated Leucine Decarboxylation in the Rat Brain in Relation to Increased Blood Ammonia Levels During Acute Hepatic Failure en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田哲也 kn-aut-sei=塩田 kn-aut-mei=哲也 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=全人工股関節置換術・全人工膝関節置換術後の深部静脈血栓症と血清D-dimer値の関連 kn-title=Changes in LPIA D-dimer after total hip or knee arthroplasty relevant to deep vein thrombosis diagnosed by bilateral ascending venography en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田直史 kn-aut-sei=塩田 kn-aut-mei=直史 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラット鉄塩誘導てんかん原性焦点におけるアミノ酸神経伝達物質に関する研究 kn-title=Amino Acid Neurotransmitters in Iron-Induced Epileptic Foci of Rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田厚 kn-aut-sei=塩田 kn-aut-mei=厚 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=22 cd-vols= no-issue=1 article-no= start-page=143 end-page=149 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=200611 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ERPsを用いた自己顔の認知過程の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩田真友子 kn-aut-sei=塩田 kn-aut-mei=真友子 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=猪原敬介 kn-aut-sei=猪原 kn-aut-mei=敬介 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=堀内孝 kn-aut-sei=堀内 kn-aut-mei=孝 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=1 article-no= start-page=7 end-page=13 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=1980 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Effect of Testosterone and Other Steroid Hormones on the Tumor Lymphocyte Lines Isolated from Chickens kn-title=リンパ腫症及びマレック病腫瘍細胞に対するテストステロンほか各種ステロイドホルモンの結果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=ニワトリのマレック病およびリンパ腫症の腫瘍リンパ球増殖に及ぼすテストステロンほか各種ステロイドホルモンの効果ならびに3H-テストステロンに対するそれらの細胞の結合量を調べた. さらに,正常リンパ球におけるテストステロンの効果およびその結合量を調べた. テストステロンのほか,エストロジェンおよびグルココルチコイドにおいて,両腫瘍細胞あるいは一方の腫瘍細胞に対する増殖抑制効果が観察された. 正常リンパ球では,テストステロンは,Bリンパ球の生存率を減少させたが,Tリンパ球に対する効果はなかった. 3H-テストステロンに対する結合量は,腫瘍細胞では多量で,Bリンパ球でも比較的多かったが,Tリンパ球では少なかった. 以上の結果から,腫瘍細胞を含めたリンパ球におけるステロイドホルモンの効果は,多量のステロイドホルモンが細胞に結合することに基づくものと結論された. さらに,リンパ球の分化に関して,Tリンパ球は成熟のある時期にテストステロンに対する感受性を失なう一方,Bリンパ球は、その感受性を保持し続けることが示唆された。 en-copyright= kn-copyright= en-aut-name=KondoYasuhiro en-aut-sei=Kondo en-aut-mei=Yasuhiro kn-aut-name=近藤康博 kn-aut-sei=近藤 kn-aut-mei=康博 aut-affil-num=1 ORCID= en-aut-name=ShiotaMasahiko en-aut-sei=Shiota en-aut-mei=Masahiko kn-aut-name=塩田雅彦 kn-aut-sei=塩田 kn-aut-mei=雅彦 aut-affil-num=2 ORCID= en-aut-name=TanabeAkira en-aut-sei=Tanabe en-aut-mei=Akira kn-aut-name=田辺昭 kn-aut-sei=田辺 kn-aut-mei=昭 aut-affil-num=3 ORCID= en-aut-name=ToriumiTooru en-aut-sei=Toriumi en-aut-mei=Tooru kn-aut-name=鳥海徹 kn-aut-sei=鳥海 kn-aut-mei=徹 aut-affil-num=4 ORCID= en-aut-name=SatoKoji en-aut-sei=Sato en-aut-mei=Koji kn-aut-name=佐藤孝二 kn-aut-sei=佐藤 kn-aut-mei=孝二 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=名古屋大学農学部 END start-ver=1.4 cd-journal=joma no-vol=33 cd-vols= no-issue=1 article-no= start-page=43 end-page=49 dt-received= dt-revised= dt-accepted= dt-pub-year=1969 dt-pub=1969 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=急傾斜山地草地の牧草生産力に関する研究 (第1報)黒毛和種若令去勢牛の放牧行動に関する調査 kn-title=Studies on Grass Productivity of Steep Mountainous Grassland : 1.Observations on the Grazing Behaviour of Young Steers of Japanese Black Breed en-subtitle= kn-subtitle= en-abstract= kn-abstract=In June, August and October of 1966, observations were made on the grazing behaviour of young steers of Japanese Black breed of cattle on an improved pasture of steep mountainous grassland. The behaviour of the herd of ten steers was recorded at 5 min. intervals throughout 48 hr. and classified into grazing, eating concentrate, eating hay, ruminating, resting and walking. The day to day variation in behaviour varied with the trial period of the year, but a general similarity of grazing pattern was found in the two successive days within each trial period. In June, the grazing pattern was divided into three distinct periods: early in the morning, about midday and in the evening. In August, the pattern was divided into two periods: in the afternoon and at night. In October, there was one distinct period in the afternoon. RT/GT value varied seasonally from 1.2 in June to 1 in August and October. The hay eating time increased to three times as long as that of June in August and four times in October. Therefore, an increase in herbage intake in June and a reserve decrease both in August and October are clearly indicated. en-copyright= kn-copyright= en-aut-name=MiakiTakashi en-aut-sei=Miaki en-aut-mei=Takashi kn-aut-name=三秋尚 kn-aut-sei=三秋 kn-aut-mei=尚 aut-affil-num=1 ORCID= en-aut-name=TanisakiMasaki en-aut-sei=Tanisaki en-aut-mei=Masaki kn-aut-name=谷酒正起 kn-aut-sei=谷酒 kn-aut-mei=正起 aut-affil-num=2 ORCID= en-aut-name=ShiotaHiroshi en-aut-sei=Shiota en-aut-mei=Hiroshi kn-aut-name=塩田汎 kn-aut-sei=塩田 kn-aut-mei=汎 aut-affil-num=3 ORCID= en-aut-name=WatanabeShigeki en-aut-sei=Watanabe en-aut-mei=Shigeki kn-aut-name=渡辺滋樹 kn-aut-sei=渡辺 kn-aut-mei=滋樹 aut-affil-num=4 ORCID= en-aut-name=KanagaYorie en-aut-sei=Kanaga en-aut-mei=Yorie kn-aut-name=嘉寿頼栄 kn-aut-sei=嘉寿 kn-aut-mei=頼栄 aut-affil-num=5 ORCID= en-aut-name=OomotoIsao en-aut-sei=Oomoto en-aut-mei=Isao kn-aut-name=大本勲 kn-aut-sei=大本 kn-aut-mei=勲 aut-affil-num=6 ORCID= en-aut-name=ShiraishiTaro en-aut-sei=Shiraishi en-aut-mei=Taro kn-aut-name=白石太郎 kn-aut-sei=白石 kn-aut-mei=太郎 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=Okayama Prefectural Experiment Station of Wagyu Cattle affil-num=5 en-affil= kn-affil=Okayama Prefectural Experiment Station of Wagyu Cattle affil-num=6 en-affil= kn-affil=Okayama Prefectural Experiment Station of Wagyu Cattle affil-num=7 en-affil= kn-affil=Okayama Prefectural Experiment Station of Wagyu Cattle END