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ID 57822
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Author
Ryuno, Hiroki Graduate School of Pharmaceutical Sciences, The University of Tokyo
Nigo, Fuki Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University
Naguro, Isao Graduate School of Pharmaceutical Sciences, The University of Tokyo
Sekimizu, Kazuhisa Institute of Medical Mycology, Teikyo University
Kaito, Chikara Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University ORCID Kaken ID publons
Abstract
Staphylococcus aureus formed bacterial aggregates in the plasma fraction of the hemolymph of silkworm, the larva of Bombyx mori, in a growth-dependent manner. The addition of arabinose or galactose inhibited the formation of S. aureus aggregates in the silkworm plasma. Formation of the bacterial aggregates depended on S. aureus genes required for the synthesis of bacterial surface polysaccharides-ypfP and ltaA, which are involved in lipoteichoic acid synthesis, and the tagO gene, which is involved in wall teichoic acid synthesis. These findings suggest that S. aureus forms bacterial aggregates in the silkworm plasma via bacterial surface teichoic acids.
Published Date
2019-05-30
Publication Title
PLoS ONE
Volume
volume14
Issue
issue5
Publisher
Public Library of Science
Start Page
e0217517
ISSN
1932-6203
Content Type
Journal Article
language
英語
OAI-PMH Set
岡山大学
Copyright Holders
Copyright: © 2019 Ryuno et al.
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DOI
Web of Science KeyUT
Related Url
isVersionOf https://doi.org/10.1371/journal.pone.0217517
License
https://creativecommons.org/licenses/by/4.0/
Citation
Ryuno H, Nigo F, Naguro I, Sekimizu K, Kaito C (2019) Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph. PLoS ONE 14(5): e0217517. https://doi.org/10.1371/journal.pone.0217517
Funder Name
Japan Society for the Promotion of Science
助成番号
15H04727
15H05783
19H03466