| ID | 56676 |
| FullText URL | |
| Author |
Ghosh, Arjun
Division of Parasitology, National Institute of Cholera & Enteric Diseases
Karmakar, Sumallya
Division of Parasitology, National Institute of Cholera & Enteric Diseases
Mukherjee, Avik K.
Division of Parasitology, National Institute of Cholera & Enteric Diseases
Raj, Dibyendu
Division of Parasitology, National Institute of Cholera & Enteric Diseases
Das, Koushik
Division of Parasitology, National Institute of Cholera & Enteric Diseases
Sarkar, Srimanti
Department of Biochemistry, Bose Institute
Nozaki, T.
Department of Parasitology, National Institute of Infectious Diseases, Japan and Graduate School of Life and Environmental Sciences, University of Tsukuba
Ganguly, Sandipan
Division of Parasitology, National Institute of Cholera & Enteric Diseases
|
| Abstract | Small nuclear Ribonucleo Protein F (snRNP F) is a spliceosomal protein that binds with U1, U2, U4/U6 and U5 small nuclear RNA (snRNA) to form spliceosomal complexes responsible for pre mRNA processing. This study reports the unusual interaction of giardial snRNP F with small nucleolar RNAs (snoRNA) that are responsible for pre rRNA processing. Electrophoretic Mobility Shift Assay was used to demonstrate the interaction of this protein with U3 and U14 class snoRNA of the early branching eukaryote Giardia lamblia. It was also evident from our study that snRNP F in Giardia is evolutionary distinct from its other eukaryotic orthologues.
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| Keywords | Giardia lamblia
snRNA
snoRNA
U3
U14
|
| Published Date | 2013
|
| Publication Title |
Global Journal of Biology, Agriculture & Health Sciences
|
| Volume | volume2
|
| Issue | issue3
|
| Publisher | Longdom Publishing
|
| Start Page | 178
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| End Page | 184
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| ISSN | 23195584
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| Content Type |
Journal Article
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| language |
English
|
| OAI-PMH Set |
岡山大学
|
| File Version | publisher
|
| Project |
Collaborative Research of Okayama University for Infectious Diseases in India
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