| JaLCDOI | 10.18926/AMO/30954 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Nakanishi, Akira| Abe, Tadashi| Watanabe, Masami| Takei, Kohji| Yamada, Hiroshi| |
| Abstract | <p>Testicular Sertoli cells highly express dynamin 2 and amphiphysin 1. Here we demonstrate that dynamin 2 is implicated in phosphatidylserine (PS)-dependent phagocytosis in Sertoli cells. Immunofluorescence and dual-live imaging revealed that dynamin 2 and amphiphysin 1 accumulate simultaneously at ruffles. These proteins are specifically bound <i>in vitro</i>. Over-expression of dominant negative dynamin 2 (K44A) inhibits liposome-uptake and leads to the mis-localization of amphiphysin 1. Thus, the cooperative function of dynamin 2 and amphiphysin 1 in PS-dependent phagocytosis is strongly suggested.</p> |
| Keywords | dynamin amphiphysin phagocytosis testis |
| Amo Type | Original Article |
| Published Date | 2008-12 |
| Publication Title | Acta Medica Okayama |
| Volume | volume62 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 385 |
| End Page | 391 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| Web of Science KeyUT | 000262025000005 |
| Author | Moriyama, Yoshinori| Hayashi, Mitsuko| Yamada, Hiroshi| Yatsushiro, Shouki| Ishio, Shougo| Yamamoto, Akitsugu| |
|---|---|
| Published Date | 2001-01 |
| Publication Title | The Journal of Experimental Biology |
| Volume | volume203 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Yamada, Hiroshi| Padilla-Parra, Sergi| Park, Sun Joo| Itoh, Toshiki| Chaineau, Mathilde| Monaldi, Ilaria| Cremona, Ottavio| Benfenati, Fabio| Camilli, Pietro De| Coppey-Moisan, Maïté| Tramier, Marc| Galli, Thierry| Takei, Kohji| |
|---|---|
| Published Date | 2011-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume123 |
| Issue | issue1 |
| Content Type | Journal Article |
| FullText URL | ijo_49_3_877.pdf |
|---|---|
| Author | Yamada, Hiroshi| Takeda, Tetsuya| Michiue, Hiroyuki| Abe, Tadashi| Takei, Kohji| |
| Published Date | 2016-06-30 |
| Publication Title | International Journal of Oncology |
| Volume | volume49 |
| Issue | issue3 |
| Publisher | Spandidos |
| Start Page | 877 |
| End Page | 886 |
| ISSN | 1019-6439 |
| NCID | AA10992511 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 27572123 |
| DOI | 10.3892/ijo.2016.3592 |
| Web of Science KeyUT | 000382447300003 |
| Related Url | isVersionOf https://doi.org/10.3892/ijo.2016.3592 |
