このエントリーをはてなブックマークに追加
ID 51865
JaLCDOI
FullText URL
Author
Takeuchi, Akihito
Ogino, Tatsuya
Hanafusa, Kaoru
Morooka, Teruko
Oka, Makio Kaken ID publons
Ohtsuka, Yoko
Abstract
To clarify the relationship between attention deficit/hyperactivity disorder (AD/HD) and pervasive developmental disorders (PDD), we investigated the common features and differences of these disorders in neuropsychological profiles. The subjects were 4 groups of Japanese boys aged 6 to 15 years, categorized by diagnosis:AD/HD (n=20), PDD with comorbid AD/HD (PDD+:n=16), PDD without comorbid AD/HD (PDD-:n=8), and typically developing (n=60). We evaluated executive function (EF) through verbal and visuospatial memory tasks, the Go/NoGo task, and the color-word matching Stroop task. We performed a categorical analysis to estimate the effects of the 3 disorders on EF and a dimensional analysis to estimate the effects of symptom scales on EF. We found that the AD/HD and PDD+ subjects had negative effects on verbal working memory and intra-individual response variability. The severity of these impairments was positively correlated with the inattentiveness score. The subjects with a PDD+ or PDD- diagnosis had poorer scores on interference control;the severity of this impairment was correlated with the PDD symptom score. Impairments in visuospatial working memory were detected in the AD/HD and PDD- groups but not in the PDD+ group. Impairments in inhibition of the pre-potent response were noted in all 3 categories. AD/HD and PDD share neuropsychological features, though each disorder has a specific impairment pattern. Our findings partially support the idea that AD/HD and PDD are on a spectrum.
Keywords
attention deficit/hyperactivity disorder
pervasive developmental disorder
executive function
working memory
color-word matching Stroop task
Amo Type
Original Article
Publication Title
Acta Medica Okayama
Published Date
2013-10
Volume
volume67
Issue
issue5
Publisher
Okayama University Medical School
Start Page
293
End Page
303
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
Copyright Holders
CopyrightⒸ 2013 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT
Related Url
http://ousar.lib.okayama-u.ac.jp/metadata/52244