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ID 49671
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Author
Yagi, Takahito Kakenhi
Umeda, Yuzo Kakenhi
Yoshida, Ryuichi ORCID Kakenhi
Sato, Daisuke
Nobuoka, Daisuke
Utsumi, Masashi
Fujiwara, Toshiyoshi ORCID Kakenhi
Abstract
We present a case of living donor liver transplantation to a 3-year disease-free survivor of liver resection for hepatocellular carcinoma (HCC) with major portal vein invasion. A 48-year-old man had HCC in the right lobe with a portal venous tumor thrombus extending into the left portal vein. An extended right lobectomy with thrombectomy was performed to remove the thrombus. Three years after liver resection, the patient experienced liver failure, with massive ascites and jaundice due to the formation of a thrombus in the main and left portal veins. During the 3 years after liver resection, no metastasis or recurrence of HCC had been detected, and tumor markers had been within normal ranges. The portal venous thrombus did not show any arterial enhancement under contrast-enhanced computed tomography, suggesting that the co-existence of any HCC component in the portal venous thrombus may have been negative. Based on these findings, living donor liver transplantation was performed using a right lobe graft from the patientʼs son. The patient is alive at 87 months after the transplantation, with no evidence of HCC recurrence.
Keywords
living donor liver transplantation
hepatocellular carcinoma
portal vein invasion
liver resection
Amo Type
Case Report
Published Date
2013-04
Publication Title
Acta Medica Okayama
Volume
volume67
Issue
issue2
Publisher
Okayama University Medical School
Start Page
117
End Page
121
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2013 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Sience KeyUT