Yasuhara, Takao - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Combined simultaneous endoscopic endonasal and transcranial surgery using high‐definition three‐dimensional exoscope for malignant tumors of the anterior skull base

FullText URL	fulltext20240319-01.pdf
Author	Makihara, Seiichiro\| Otani, Yoshihiro\| Uraguchi, Kensuke\| Shimizu, Aiko\| Murai, Aya\| Higaki, Takaya\| Akisada, Naoki\| Fujimoto, Shohei\| Makino, Takuma\| Ishida, Joji\| Fujii, Kentaro\| Yasuhara, Takao\| Ota, Tomoyuki\| Matsumoto, Hiroshi\| Ando, Mizuo\|
Keywords	anterior skull base malignant tumors anterolateral thigh flap endoscopic endonasal and transcranial surgery ORBEYE skull base reconstruction
Published Date	2024-03-07
Publication Title	Head & Neck
Volume	volume46
Issue	issue5
Publisher	Wiley
Start Page	1074
End Page	1082
ISSN	1043-3074
NCID	AA10732962
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	38450867
DOI	10.1002/hed.27724
Web of Science KeyUT	001179620500001
Related Url	isVersionOf https://doi.org/10.1002/hed.27724

Targeting Neurogenesis in Seeking Novel Treatments for Ischemic Stroke

FullText URL	fulltext.pdf
Author	Nagase, Takayuki\| Kin, Kyohei\| Yasuhara, Takao\|
Keywords	neurogenesis ischemic stroke cell therapy rehabilitations
Published Date	2023-10-13
Publication Title	Biomedicines
Volume	volume11
Issue	issue10
Publisher	MDPI
Start Page	2773
ISSN	2227-9059
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	37893146
DOI	10.3390/biomedicines11102773
Web of Science KeyUT	001094090900001
Related Url	isVersionOf https://doi.org/10.3390/biomedicines11102773

Continuous vagus nerve stimulation exerts beneficial effects on rats with experimentally induced Parkinson's disease: Evidence suggesting involvement of a vagal afferent pathway

FullText URL	fulltext.pdf
Author	Hosomoto, Kakeru\| Sasaki, Tatsuya\| Yasuhara, Takao\| Kameda, Masahiro\| Sasada, Susumu\| Kin, Ittetsu\| Kuwahara, Ken\| Kawauchi, Satoshi\| Okazaki, Yosuke\| Yabuno, Satoru\| Sugahara, Chiaki\| Kawai, Koji\| Nagase, Takayuki\| Tanimoto, Shun\| Borlongan, Cesario V.\| Date, Isao\|
Keywords	Parkinson's disease Vagus nerve stimulation Afferent pathway Locus coeruleus Dopamine Noradrenaline
Published Date	2023-03
Publication Title	Brain Stimulation
Volume	volume16
Issue	issue2
Publisher	Elsevier Science INC
Start Page	594
End Page	603
ISSN	1935-861X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 Published by Elsevier Inc.
File Version	publisher
PubMed ID	36914065
DOI	10.1016/j.brs.2023.03.003
Web of Science KeyUT	000951899800001
Related Url	isVersionOf https://doi.org/10.1016/j.brs.2023.03.003

Synergistic therapeutic effects of intracerebral transplantation of human modified bone marrow-derived stromal cells (SB623) and voluntary exercise with running wheel in a rat model of ischemic stroke

FullText URL	fulltext.pdf correction.pdf
Author	Yabuno, Satoru\| Yasuhara, Takao\| Nagase, Takayuki\| Kawauchi, Satoshi\| Sugahara, Chiaki\| Okazaki, Yosuke\| Hosomoto, Kakeru\| Sasada, Susumu\| Sasaki, Tatsuya\| Tajiri, Naoki\| Borlongan, Cesar V.\| Date, Isao\|
Keywords	Cerebral ischemic infarct Rehabilitation Regenerative medicine SB623 Voluntary exercise
Published Date	2023-01-24
Publication Title	STEM Cell Research & Therapy
Volume	volume14
Issue	issue1
Publisher	BMC
Start Page	10
ISSN	1757-6512
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2023.
File Version	publisher
PubMed ID	36691091
DOI	10.1186/s13287-023-03236-4
Web of Science KeyUT	000920132500001
Related Url	isVersionOf https://doi.org/10.1186/s13287-023-03236-4

Transplantation of modified human bone marrow-derived stromal cells affords therapeutic effects on cerebral ischemia in rats

FullText URL	fulltext.pdf
Author	Kawauchi, Satoshi\| Yasuhara, Takao\| Kin, Kyohei\| Yabuno, Satoru\| Sugahara, Chiaki\| Nagase, Takayuki\| Hosomoto, Kakeru\| Okazaki, Yosuke\| Tomita, Yousuke\| Umakoshi, Michiari\| Sasaki, Tatsuya\| Kameda, Masahiro\| Borlongan, Cesario, V\| Date, Isao\|
Keywords	bone marrow stromal cells cerebral infarction encapsulated cell transplantation middle cerebral artery occlusion model neurogenesis
Published Date	2022-08-24
Publication Title	Cns Neuroscience & Therapeutics
Publisher	Wiley
ISSN	1755-5930
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	36000240
DOI	10.1111/cns.13947
Web of Science KeyUT	000846694400001
Related Url	isVersionOf https://doi.org/10.1111/cns.13947

Spinal Surgery after Bilateral Subthalamic Stimulation for Patients with Parkinson's Disease: A Retrospective Outcome Analysis of Pain and Functional Control

FullText URL	fulltext.pdf
Author	Umakoshi, Michiari\| Yasuhara, Takao\| Morimoto, Jun\| Murai, Satoshi\| Sasaki, Tatsuya\| Kameda, Masahiro\| Kin, Kyohei\| Miyoshi, Yasuyuki\| Date, Isao\|
Keywords	abnormal posture lumbago neuromodulation pain spinal alignment
Published Date	2021-10
Publication Title	Neurologia medico-chirurgica
Volume	volume61
Issue	issue10
Publisher	The Japan Neurosurgical Society
Start Page	607
End Page	618
ISSN	0470-8105
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japan Neurosurgical Society
File Version	publisher
PubMed ID	34408107
DOI	10.2176/nmc.oa.2021-0094
Web of Science KeyUT	000710287800007
Related Url	isVersionOf https://doi.org/10.2176/nmc.oa.2021-0094

Ultra-high-molecular-weight Polyethylene (UHMWPE) Wing Method for Strong Cranioplasty

FullText URL	fulltext.pdf
Author	Kobayashi, Kazuki\| Yukiue, Tadato\| Yoshida, Hideyuki\| Tsuboi, Nobushige\| Takahashi, Yuu\| Makino, Keigo\| Kimura, Ryu\| Mizuta, Ryo\| Sasada, Susumu\| Ogawa, Tomoyuki\| Nagayama, Noriyuki\| Yasuhara, Takao\| Date, Isao\|
Keywords	artificial bone cranioplasty finite element analyses ultra-high-molecular-weight polyethylene
Published Date	2021
Publication Title	Neurologia Medico-Chirurgica
Volume	volume61
Issue	issue9
Publisher	The Japan Neurosurgical Society
Start Page	549
End Page	556
ISSN	0470-8105
NCID	AN00358613
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japan Neurosurgical Society
File Version	publisher
PubMed ID	34092749
DOI	10.2176/nmc.oa.2021-0032
Web of Science KeyUT	000697159800006
Related Url	isVersionOf https://doi.org/10.2176/nmc.oa.2021-0032

Vagus Nerve Stimulation with Mild Stimulation Intensity Exerts Anti-Inflammatory and Neuroprotective Effects in Parkinson's Disease Model Rats

FullText URL	fulltext.pdf
Author	Kin, Ittetsu\| Sasaki, Tatsuya\| Yasuhara, Takao\| Kameda, Masahiro\| Agari, Takashi\| Okazaki, Mihoko\| Hosomoto, Kakeru\| Okazaki, Yosuke\| Yabuno, Satoru\| Kawauchi, Satoshi\| Kuwahara, Ken\| Morimoto, Jun\| Kin, Kyohei\| Umakoshi, Michiari\| Tomita, Yousuke\| Tajiri, Naoki\| Borlongan, Cesario, V\| Date, Isao\|
Keywords	anti-inflammation less invasive therapy new experimental device Parkinson's disease vagus nerve stimulation
Published Date	2021-07-07
Publication Title	Biomedicines
Volume	volume9
Issue	issue7
Publisher	MDPI
Start Page	789
ISSN	2227-9059
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
DOI	10.3390/biomedicines9070789
Web of Science KeyUT	000676794000001
Related Url	isVersionOf https://doi.org/10.3390/biomedicines9070789

An Evaluation of the Safety and Feasibility of Adenosine-assisted Clipping Surgery for Unruptured Cerebral Aneurysms: Study Protocol

FullText URL	fulltext.pdf
Author	Hishikawa, Tomohito\| Murai, Satoshi\| Hiramatsu, Masafumi\| Haruma, Jun\| Nishi, Kazuhiko\| Ebisudani, Yuki\| Sato, Yu\| Yasuhara, Takao\| Sugiu, Kenji\| Shimizu, Kazuyoshi\| Kobayashi, Motomu\| Nakagawa, Koji\| Kimura-Ono, Aya\| Hotta, Katsuyuki\| Morimatsu, Hiroshi\| Date, Isao\|
Keywords	adenosine clipping unruptured cerebral aneurysm
Published Date	2021
Publication Title	Neurologia Medico-Chirurgica
Volume	volume61
Issue	issue7
Publisher	Japan Neurosurgical Soc.
Start Page	393
End Page	396
ISSN	0470-8105
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japan Neurosurgical Society
File Version	publisher
PubMed ID	34024879
DOI	10.2176/nmc.st.2021-0018
Web of Science KeyUT	000672804200001
Related Url	isVersionOf https://doi.org/10.2176/nmc.st.2021-0018

Japanese National Questionnaire Survey in 2018 on Complications Related to Cranial Implants in Neurosurgery

FullText URL	fulltext.pdf
Author	YASUHARA, Takao\| MURAI, Satoshi\| MIKUNI, Nobuhiro\| MIYAMOTO, Susumu\| DATE, Isao\|
Keywords	artificial bone cranioplasty infection re-operation titanium plate
Published Date	2020
Publication Title	Neurologia medico-chirurgica
Volume	volume60
Issue	issue7
Publisher	The Japan Neurosurgical Society
Start Page	337
End Page	350
ISSN	0470-8105
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by The Japan Neurosurgical Society
PubMed ID	32536658
DOI	10.2176/nmc.oa.2020-0051
Web of Science KeyUT	000548315700003
Related Url	isVersionOf https://doi.org/10.2176/nmc.oa.2020-0051

Cerebral circulation improves with indirect bypass surgery combined with gene therapy

FullText URL	fulltext.pdf
Author	Shear, Alex\| Nishihiro, Shingo\| Hishikawa, Tomohito\| Hiramatsu, Masafumi\| Sugiu, Kenji\| Yasuhara, Takao\| Date, Isao\|
Keywords	Angiogenesis cerebral hypoperfusion encephalo-myo-synangiosis endothelial progenitor cells high-mobility group box-1 revascularization vascular endothelial growth factor
Published Date	2019-09-30
Publication Title	Brain Circulation
Volume	volume5
Issue	issue3
Publisher	Wolters Kluwer
Start Page	119
End Page	123
ISSN	2394-8108
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 Brain Circulation
File Version	publisher
PubMed ID	31620658
DOI	10.4103/bc.bc_33_19
Web of Science KeyUT	000562137100005
Related Url	isVersionOf https://doi.org/10.4103/bc.bc_33_19

Precise MEP monitoring with a reduced interval is safe and useful for detecting permissive duration for temporary clipping

FullText URL	fulltext.pdf
Author	Kameda, Masahiro\| Hishikawa, Tomohito\| Hiramatsu, Masafumi\| Yasuhara, Takao\| Kurozumi, Kazuhiko\| Date, Isao\|
Keywords	Stroke
Published Date	2020-02-26
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	3507
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32103082
DOI	10.1038/s41598-020-60377-9
Web of Science KeyUT	000563210400001
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-60377-9

Long-Term Continuous Cervical Spinal Cord Stimulation Exerts Neuroprotective Effects in Experimental Parkinson's Disease

FullText URL	fulltext.pdf
Author	Kuwahara, Ken\| Sasaki, Tatsuya\| Yasuhara, Takao\| Kameda, Masahiro\| Okazaki, Yosuke\| Hosomoto, Kakeru\| Kin, Ittetsu\| Okazaki, Mihoko\| Yabuno, Satoru\| Kawauchi, Satoshi\| Tomita, Yousuke\| Umakoshi, Michiari\| Kin, Kyohei\| Morimoto, Jun\| Lee, Jea-Young\| Tajiri, Naoki\| Borlongan, Cesar V.\| Date, Isao\|
Keywords	electrical stimulation neuroinflammation neuromodulation neuroprotection 6-hydroxydopamine
Published Date	2020-06-16
Publication Title	Frontiers in Aging Neuroscience
Volume	volume12
Publisher	Frontiers Media
Start Page	164
ISSN	1663-4365
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Kuwahara et al.
File Version	publisher
PubMed ID	32612523
DOI	10.3389/fnagi.2020.00164
Web of Science KeyUT	000546853500001
Related Url	isVersionOf https://doi.org/10.3389/fnagi.2020.00164

Cerebellar Blood Flow and Gene Expression in Crossed Cerebellar Diaschisis after Transient Middle Cerebral Artery Occlusion in Rats

FullText URL	fulltext.pdf
Author	Kidani, Naoya\| Hishikawa, Tomohito\| Hiramatsu, Masafumi\| Nishihiro, Shingo\| Kin, Kyohei\| Takahashi, Yu\| Murai, Satoshi\| Sugiu, Kenji\| Yasuhara, Takao\| Miyazaki, Ikuko\| Asanuma, Masato\| Date, Isao\|
Keywords	apoptosis cerebral blood flow crossed cerebellar diaschisis ischemic stroke oxidative stress
Published Date	2020-06-10
Publication Title	International Journal of Molecular Sciences
Volume	volume21
Issue	issue11
Publisher	MDPI
Start Page	4137
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32531947
DOI	10.3390/ijms21114137
Web of Science KeyUT	000543400300399
Related Url	isVersionOf https://doi.org/10.3390/ijms21114137

Animal Models for Parkinson's Disease Research: Trends in the 2000s

FullText URL	fulltext.pdf
Author	Kin, Kyohei\| Yasuhara, Takao\| Kameda, Masahiro\| Date, Isao\|
Keywords	animal model alpha-synuclein DJ-1 neurotoxin Parkin Parkinson's disease pesticide PINK1 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 6-hydroxydopamine
Published Date	2019-10-30
Publication Title	International Journal of Molecular Sciences
Volume	volume20
Issue	issue21
Publisher	MDPI
Start Page	E5402
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors.
File Version	publisher
PubMed ID	31671557
DOI	10.3390/ijms20215402
Web of Science KeyUT	000498946100160
Related Url	isVersionOf https://doi.org/10.3390/ijms20215402

Cognitive functions in Parkinson's disease: Relation to disease severity and hallucination

Author	Wakamori, Takaaki\| Agari, Takashi\| Yasuhara, Takao\| Kameda, Masahiro\| Kondo, Akihiko\| Shinko, Aiko\| Sasada, Susumu\| Sasaki, Tatsuya\| Furuta, Tomohisa\| Date, Isao\|
Published Date	2014-04
Publication Title	Parkinsonism and Related Disorders
Volume	volume20
Issue	issue4
Content Type	Journal Article

The neuroprotective and neurorescue effects of carbamylated erythropoietin Fc fusion protein (CEPO-Fc) in a rat model of Parkinson's disease

Author	Tayra, Judith Thomas\| Kameda, Masahiro\| Yasuhara, Takao\| Agari, Takashi\| Kadota, Tomohito\| Wang, Feifei\| Kikuchi, Yoichiro\| Liang, Hanbai\| Shinko, Aiko\| Wakamori, Takaaki\| Vcelar, Brigitta\| Weik, Robert\| Date, Isao\|
Published Date	2013-03-28
Publication Title	Brain Research
Volume	volume1502
Content Type	Journal Article

A Case of Radiation-Induced Osteosarcoma with RB1 Gene Alteration Treated by Skull Base Surgery and Craniofacial Reconstruction

JaLCDOI	10.18926/AMO/64367
FullText URL	77_1_85.pdf
Author	Matsuda, Yuki\| Otani, Yoshihiro\| Yasuhara, Takao\| Ando, Mizuo\| Higaki, Takaya\| Makino, Takuma\| Matsumoto, Hiroshi\| Oyama, Tadashi\| Nishimori, Hisakazu\| Date, Isao\|
Abstract	A 35-year-old female presented with headache, photophobia and developed sudden loss of vision after having undergone right-side ophthalmectomy and radiochemotherapy for retinoblastoma in infancy. A neoplastic lesion was found in the left middle cranial fossa and was surgically removed. The diagnosis was radiation-induced osteosarcoma with RB1 gene alteration. Although she received chemotherapy for the residual tumor, it progressed 17 months later. Maximal surgical resection with craniofacial reconstruction was required. We utilized two three-dimensional models for surgical planning. She was discharged without neurological deficits other than loss of light perception subsequent to left ophthalmectomy. In cases where retinoblastoma is treated with radiotherapy, long-term follow-up is necessary to monitor for radiation-induced tumor development.
Keywords	bone model skull base surgery radiation-induced osteosarcoma RB1 gene alteration
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2023-02
Volume	volume77
Issue	issue1
Publisher	Okayama University Medical School
Start Page	85
End Page	90
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2023 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	36849151
Web of Science KeyUT	000952978000001

Pyogenic Ventriculitis After Anterior Skull Base Surgery Treated With Endoscopic Ventricular Irrigation And Reconstruction Using a Vascularized Flap

JaLCDOI	10.18926/AMO/61908
FullText URL	75_2_243.pdf
Author	Tomita, Yusuke\| Shimazu, Yosuke\| Kawakami, Masato\| Matsumoto, Hiroshi\| Fujii, Kentaro\| Kameda, Masahiro\| Yasuhara, Takao\| Suruga, Yasuki\| Ota, Tomoyuki\| Kimata, Yoshihiro\| Kurozumi, Kazuhiko\| Date, Isao\|
Abstract	Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection cavity were reconstructed using a vascularized anterolateral thigh adipofascial flap. His symptoms disappeared, indicating that endoscopic irrigation and reconstruction can effectively address ventriculitis even in patients in critical clinical condition.
Keywords	ventriculitis surgical site infection intraventricular antimicrobial therapy anterior skull base surgery
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2021-04
Volume	volume75
Issue	issue2
Publisher	Okayama University Medical School
Start Page	243
End Page	248
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2021 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33953433
NAID	120007029879

Mesenchymal Stem Cell Therapy for Ischemic Stroke

JaLCDOI	10.18926/AMO/55302
FullText URL	71_4_263.pdf
Author	Toyoshima, Atsuhiko\| Yasuhara, Takao\| Date, Isao\|
Abstract	To date, many animal studies have indicated the neuroprotective effects of mesenchymal stem cell (MSC) transplantation in ischemic stroke. Several clinical studies have also revealed the safety, feasibility, and neuroprotective effects in ischemic stroke patients. In this review, we present the main approaches of MSC transplantation in ischemic stroke, the mechanisms of MSC therapy, and the current clinical studies on MSC transplantation in ischemic stroke patients. We also explore the safety of MSC transplantation and conclude that MSC therapy will play an important role in the future treatment of ischemic stroke. The optimal timing, approach, and cell dose in the transplantation are important issues for successful clinical application.
Keywords	mesenchymal stem cell ischemic stroke cell transplantation clinical trial
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2017-08
Volume	volume71
Issue	issue4
Publisher	Okayama University Medical School
Start Page	263
End Page	268
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2017 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	28824181