JaLCDOI | 10.18926/AMO/54511 |
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FullText URL | 70_4_313.pdf |
Author | Matsumoto, Kazuyuki| Kato, Hironari| Tsutsumi, Koichiro| Mizukawa, Sho| Yabe, Syuntaro| Seki, Hiroyuki| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Yamamoto, Naoki| Horiguchi, Shigeru| Okada, Hiroyuki| |
Abstract | Recently, endoscopic ultrasonography (EUS)-guided ethanol ablation for small pancreatic neuroendocrine tumors (p-NETs) has been reported. However, the efficacy and safety of the technique remain unclear. We have launched a prospective pilot study of EUS-guided ethanol ablation for p-NETs. The major eligibility criteria are the presence of a pathologically diagnosed grade (G) 1 or G2 p-NET, a tumor size of 2cm, and being a poor candidate for surgery. A total of 5 patients will be treated. The primary endpoint will be the complete ablation rate at 1 month after treatment. |
Keywords | pancreatic neuroendocrine tumor ethanol ablation EUS-guided |
Amo Type | Clinical Study Protocols |
Publication Title | Acta Medica Okayama |
Published Date | 2016-08 |
Volume | volume70 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 313 |
End Page | 316 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 27549680 |
Web of Science KeyUT | 000384748600015 |
JaLCDOI | 10.18926/AMO/54513 |
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FullText URL | 70_4_323.pdf |
Author | Yamamoto, Naoki| Kato, Hironari| Mizukawa, Sho| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
Abstract | Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) with contrast agent enabled us to assess the hemodynamics closely, despite limited data in pancreatic tumors. We have initiated a prospective, single arm, and non-randomized study to clarify the accuracy and safety of CH-EUS with Sonazoid and time-intensity curve (TIC) analysis for diagnosing benign or malignant pancreatic tumors. A total of 200 patients will undergo CH-EUS and TIC analysis. Receiver operating characteristic (ROC) analysis will be used to determine the optimal parameter cutoff values for TIC analysis. This will clarify whether CH-EUS and TIC can further improve the diagnosis of pancreatic tumors over conventional EUS. |
Keywords | CH-EUS pancreatic tumor TIC |
Amo Type | Clinical Study Protocols |
Publication Title | Acta Medica Okayama |
Published Date | 2016-08 |
Volume | volume70 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 323 |
End Page | 325 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 27549682 |
Web of Science KeyUT | 000384748600017 |
JaLCDOI | 10.18926/AMO/54605 |
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FullText URL | 70_5_417.pdf |
Author | Mizukawa, Sho| Kato, Hironari| Muro, Shinichiro| Akimoto, Yutaka| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Yamamoto, Naoki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| Inoue, Hirofumi| Tanaka, Noriyuki| |
Abstract | Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a standard procedure for precise histological diagnosis of pancreas tumors, but it is sometimes difficult to obtain adequate specimens. EUS Sonopsy CY® is a newly designed needle with original features. This randomized study will compare the tissue collection rate of EUS Sonopsy CY® to that of a conventional needle in EUS-FNA. The major eligibility criteria are as follows: Patients with a pancreatic mass referred for EUSFNA; age ≥20 years, and performance status<4. The primary outcome is the tissue collection rate. This study will elucidate the efficacy of EUS Sonopsy CY®. |
Keywords | endoscopic ultrasound-guided fine needle aspiration pancreatic cancer Menghini type needle tip |
Amo Type | Clinical Study Protocols |
Publication Title | Acta Medica Okayama |
Published Date | 2016-10 |
Volume | volume70 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 417 |
End Page | 420 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 27777439 |
Web of Science KeyUT | 000388098700016 |