start-ver=1.4
cd-journal=joma
no-vol=9
cd-vols=
no-issue=
article-no=
start-page=51
end-page=60
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20131230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The State of Oregon: An Overview 2
kn-title=オレゴン州概観（２）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=　オレゴン州はアメリカ合衆国本土太平洋岸の３つの州のうち中間に位置する州である。日本との経済的な結びつきも強く、仕事や観光あるいは留学といった目的で同州を訪れる人は多い。目的がそのいずれであっても、オレゴン州についてある程度の予備知識を持って現地入りした方が、そうでない場合と比べ、より実り多い結果を期待できるであろう。しかし日本では、アメリカ合衆国に関する情報は大量に流通しているようにみえるが、個々の州や地方に関する情報、ことに日本語で書かれたものとなると意外に限定される。その空白を埋める試みとして、オレゴン州の地理・歴史、政治・経済、社会・文化などについて、公的機関やメディアの情報と独自取材をもとに概要を紹介する。（その２）
en-copyright=
kn-copyright=

en-aut-name=YanoMasaaki
en-aut-sei=Yano
en-aut-mei=Masaaki
kn-aut-name=矢野正昭
kn-aut-sei=矢野
kn-aut-mei=正昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学教育開発センター
en-keyword=アメリカ合衆国
kn-keyword=アメリカ合衆国
en-keyword=オレゴン州
kn-keyword=オレゴン州
en-keyword=地理・歴史
kn-keyword=地理・歴史
en-keyword=政治・経済
kn-keyword=政治・経済
en-keyword=社会・文化
kn-keyword=社会・文化
END

start-ver=1.4
cd-journal=joma
no-vol=8
cd-vols=
no-issue=
article-no=
start-page=29
end-page=38
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=20121231
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The State of Oregon： An Overview １
kn-title=オレゴン州概観（１）
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=オレゴン州はアメリカ合衆国本土太平洋岸の３つの州のうち中間に位置する州である。
日本との経済的な結びつきも強く、仕事や観光あるいは留学といった目的で同州を訪れる
人は多い。目的がそのいずれであっても、オレゴン州についてある程度の予備知識を持っ
て現地入りした方が、そうでない場合と比べ、より実り多い結果を期待できるであろう。し
かし日本では、アメリカ合衆国に関する情報は大量に流通しているようにみえるが、個々
の州や地方に関する情報、ことに日本語で書かれたものとなると意外に限定される。その
空白を埋める試みとして、オレゴン州の地理・歴史、政治・経済、社会・文化などについ
て、公的機関やメディアの情報と独自取材をもとに概要を紹介する。（その１）
en-copyright=
kn-copyright=

en-aut-name=YanoMasaaki
en-aut-sei=Yano
en-aut-mei=Masaaki
kn-aut-name=矢野正昭
kn-aut-sei=矢野
kn-aut-mei=正昭
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学教育開発センター
en-keyword=アメリカ合衆国
kn-keyword=アメリカ合衆国
en-keyword=オレゴン州
kn-keyword=オレゴン州
en-keyword=地理・歴史
kn-keyword=地理・歴史
en-keyword=政治・経済
kn-keyword=政治・経済
en-keyword=社会・文化
kn-keyword=社会・文化
END

start-ver=1.4
cd-journal=joma
no-vol=112
cd-vols=
no-issue=1
article-no=
start-page=8
end-page=13
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20041020
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In an attempt to identify tumor suppressor genes on chromosome 10 in non-small cell lung
cancers, we isolated 10 types of splicing variants of the HELLS/ SMARCA6 gene transcripts.
HELLS/SMARCA6 is a novel member of SNF2 family, which is implicated in cellular function like chromatin remodeling. Variant 1 was an alternatively spliced isoform containing
an insertion of a 44-ntd intronic sequence between exons 3 and 4, giving rise to a premature
termination of translation. The expression of the variant 1 was detected exclusively in the
lung cancer specimens (11 of 43 cases, 26%), but was not detected in corresponding normal tissues. D10S520 marker in the proximity of the HELLS/SMARCA6 gene showed prevalent allelic loss (41%) as compared with flanking markers (25-31%). These results suggest that loss of function of HELLS/SMARCA6 by allelic loss and aberrant proteins by tumor-specific exon creation may result in epigenetic deregulation, leading the lung cells to malignancy or its progression.
en-copyright=
kn-copyright=

en-aut-name=YanoMasaaki
en-aut-sei=Yano
en-aut-mei=Masaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=OuchidaMamoru
en-aut-sei=Ouchida
en-aut-mei=Mamoru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=ShigematsuHisayuki
en-aut-sei=Shigematsu
en-aut-mei=Hisayuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=TanakaNoriyoshi
en-aut-sei=Tanaka
en-aut-mei=Noriyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=IchimuraKoichi
en-aut-sei=Ichimura
en-aut-mei=Koichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=KobayashiKazuyasu
en-aut-sei=Kobayashi
en-aut-mei=Kazuyasu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=InakiYasuhiko
en-aut-sei=Inaki
en-aut-mei=Yasuhiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=ToyookaShinichi
en-aut-sei=Toyooka
en-aut-mei=Shinichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

en-aut-name=TsukudaKazunori
en-aut-sei=Tsukuda
en-aut-mei=Kazunori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=

en-aut-name=ShimizuNobuyoshi
en-aut-sei=Shimizu
en-aut-mei=Nobuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=

en-aut-name=ShimizuKenji
en-aut-sei=Shimizu
en-aut-mei=Kenji
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Molecular Genetics, Graduate School of Medicine and Dentistry, Okayama University

affil-num=3
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=4
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=5
en-affil=
kn-affil=Department of Pathology, Graduate School of Medicine and Dentistry, Okayama University

affil-num=6
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=7
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=8
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=9
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=10
en-affil=
kn-affil=Department of Surgical Oncology and Thoracic Surgery, Graduate School of Medicine and Dentistry, Okayama University

affil-num=11
en-affil=
kn-affil=Department of Molecular Genetics, Graduate School of Medicine and Dentistry, Okayama University
en-keyword=alternative splicing
kn-keyword=alternative splicing
en-keyword=HELLS
kn-keyword=HELLS
en-keyword=loss of heterozygosity
kn-keyword=loss of heterozygosity
en-keyword=lung cancer
kn-keyword=lung cancer
en-keyword=SMARCA6
kn-keyword=SMARCA6
END

start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2004
dt-pub=20040930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=非小細胞肺癌組織に腫瘍特異的に認められたHells/SMARCA6遺伝子のスプライシング異常に関する研究
kn-title=TUMOR-SPECIFIC EXON CREATION OF THE HELLS/SMARCA6 GENE IN NON-SMALL CELL LUNG CANCERS
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=

en-aut-name=YanoMasaaki
en-aut-sei=Yano
en-aut-mei=Masaaki
kn-aut-name=矢野匡亮
kn-aut-sei=矢野
kn-aut-mei=匡亮
aut-affil-num=1
ORCID=

affil-num=1
en-affil=
kn-affil=岡山大学
END