| FullText URL | CTR375_3_743.pdf |
|---|---|
| Author | Ojima, Fumiya| Saito, Yuka| Tsuchiya, Yukiko| Ogoshi, Maho| Fukamachi, Hiroshi| Inagaki, Kenichi| Otsuka, Fumio| Takeuchi, Sakae| Takahashi, Sumio| |
| Keywords | Estrogen Follicle Mouse Ovary Runx3 |
| Published Date | 2018-10-30 |
| Publication Title | Cell and Tissue Research |
| Volume | volume375 |
| Issue | issue3 |
| Publisher | Springer |
| Start Page | 743 |
| End Page | 754 |
| ISSN | 0302-766X |
| NCID | AA00600105 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30377784 |
| DOI | 10.1007/s00441-018-2947-2 |
| Web of Science KeyUT | 000460535300015 |
| Related Url | isVersionOf https://doi.org/10.1007/s00441-018-2947-2 |
| Title Alternative | Transcription factor Runx3 in the mouse hypothalamo-pituitary-gonadal system |
|---|---|
| FullText URL | poalas_034_002.pdf |
| Author | Takahashi, Sumio| |
| Abstract | Runx3 is a transcription factor that belongs to the Runx family. Female Runx3 knockout (Runx3−⁄−) mouse was anovulatory and infertile. Ovarian transplantation experiment suggested that lack of ovulation in Runx3−⁄− mice was caused by alteration of gonadotropin secretion in Runx3−⁄− mice. Cyp11a1 mRNA expression was less in Runx3−⁄− mouse ovaries than in wt ones. Hypothalamic Gnrh1 mRNA was increased, and Kiss1 mRNA expression in the anteroventral periventricular nucleus was decreased, but Kisspeptin mRNA in the arcuate nucleus was increased in Runx3-/- mice. Pituitary Fshb mRNA levels were increased in Runx3−⁄− mice. Cholesterol side-chain cleavage enzyme gene (Cyp11a1) expression was decreased in ovaries of Runx3−⁄− mice. These findings suggest that anovulation in Runx3−⁄− mice was partly due to the alterations in hypothalamus-pituitary-ovary system. Runx3 plays a key role in female reproduction through alteration of gonadotropin secretion. |
| Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
| Published Date | 2018-04 |
| Volume | volume34 |
| Start Page | 2 |
| End Page | 4 |
| language | Japanese |
| File Version | publisher |
| Title Alternative | Identification of Marker Gene of Pars Tuberalis Morphogenesis in Chicken Embryo. The expression of Cytokine-like 1 and Gap junction protein alpha 5 in the pars tuberalis |
|---|---|
| FullText URL | poalas_033_031_034.pdf |
| Author | Aizawa, Sayaka | Higaki, Yuriko| Ogoshi, Maho| Takeuchi, Sakae| Takahashi, Sumio| |
| Abstract | Adenohypophysis delivered from oral ectoderm consists of pars distalis (PD), pars intermedia and pars tuberalis (PT). The mechanisms of development of PD has been well studied, and the cell differentiation of PD has been well understood. However, the morphogenesis and the differentiation of PT are still unclear, and the gene expression during the PT development remains largely unknown. In this study, we explored the specifically expressing genes in PT during development and analyzed its spatiotemporal expressions pattern. Microarray analysis on laser-captured PT and PD tissues obtained from chicken embryos on embryonic day 10 (E10.0) showed high expressing genes, Cytokine-like 1 (CYTL1) and Gap junction protein alpha 5 (GJA5) in PT. A detail analysis of spatiotemporal expressions pattern during chick embryo development by in situ hybridization revealed that CYTL1 mRNA was first detected in lateral head ectoderm and ventral head ectoderm in E1.5. The CYTL1 expressions moved into Rathke’s pouch at E2.5, then it was localized in PT primordium and continuously expressed in PT primordium until E12.0. On the other hand, GJA5 mRNA was transiently detected in PT primordium from E6 to E14.0, while the expression was not detected in PD during development. These results suggested that these genes may be involved in the regulation mechanism of PT development and could be a useful marker in the PT development. |
| Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
| Published Date | 2017-04 |
| Volume | volume33 |
| Start Page | 31 |
| End Page | 34 |
| language | Japanese |
| File Version | publisher |
| Author | Kugimoto, Ayako| Aizawa, Sayaka| Ogoshi, Maho| Takahashi, Sumio| Takeuchi, Sakae| |
|---|---|
| Published Date | 2016-04 |
| Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
| Volume | volume32 |
| Content Type | Journal Article |
| Author | Tokumori, Megumi| Ogoshi, Maho| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2015-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume31 |
| Content Type | Journal Article |
| Author | Takahashi, Toru| Nishio, Kaori| Ogoshi, Maho| Takahashi, Sumio| Takeuchi, Sakae| |
|---|---|
| Published Date | 2014-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume30 |
| Content Type | Journal Article |
| Author | Ohtsuki, Takashi| Otsuki, Mariko| Murakami, Yousuke| Maekawa, Tetsuya| Yamamoto, Takashi| Akasaka, Koji| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2005-09 |
| Publication Title | Zoological Science |
| Volume | volume22 |
| Issue | issue9 |
| Content Type | Journal Article |
| Author | Kusumoto, Kenji| Murakami, Yousuke| Otsuki, Mariko| Kanayama, Munetoshi| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2005-09 |
| Publication Title | Zoological Science |
| Volume | volume22 |
| Issue | issue9 |
| Content Type | Journal Article |
| Author | Rajapakse, Sanath| Ogiwara, Katsueki| Yamano, Noriko| Kimura, Atsushi| Hirata, Kensaku| Takahashi, Sumio| Takahashi, Takayuki| |
|---|---|
| Published Date | 2006-11 |
| Publication Title | Zoological Science |
| Volume | volume23 |
| Issue | issue11 |
| Content Type | Journal Article |
| Author | Ohtsuki, Takashi| Otsuki, Mariko| Murakami, Yousuke| Hirata, Kensaku| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2007-03 |
| Publication Title | Zoological Science |
| Volume | volume24 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Maekawa, Tetsuya| Takeuchi, Sakae| Kanayama, Munetoshi| Takahashi, Sumio| |
|---|---|
| Published Date | 2009-02 |
| Publication Title | Zoological Science |
| Volume | volume26 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Honda, Junichi| Takeuchi, Sakae| Fukumachi, Hiroshi| Takahashi, Sumio| |
|---|---|
| Published Date | 1998-08 |
| Publication Title | Zoological Science |
| Volume | volume15 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Morooka, Yoshiaki| Oomizu, Souichi| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 1998-08 |
| Publication Title | Zoological Science |
| Volume | volume15 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Shiraga, Masahiro| Komatsu, Noriko| Teshigawara, Kiyoshi| Okada, Akinobu| Takeuchi, Sakae| Fukamachi, Hiroshi| Takahashi, Sumio| |
|---|---|
| Published Date | 2000-07 |
| Publication Title | Zoological Science |
| Volume | volume17 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Kakeya, Tomoshi| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2002-07 |
| Publication Title | Zoological Science |
| Volume | volume19 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Sharma, Seema| Oomizu, Souichi| Kakeya, Tomoshi| Masui, Tohru| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2003-01 |
| Publication Title | Zoological Science |
| Volume | volume20 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Komatsu, Noriko| Maekawa, Tetsuya| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2003-05 |
| Publication Title | Zoological Science |
| Volume | volume20 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Takahashi, Sumio| |
|---|---|
| Published Date | 2004-06 |
| Publication Title | Zoological Science |
| Volume | volume21 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Taniuchi, Shusuke| Takahashi, Sumio| Takeuchi, Sakae| |
|---|---|
| Published Date | 2011-05 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume27 |
| Content Type | Journal Article |
| Author | Tsuchiya, Yukiko| Sakuma, Atsuko| Takeuchi, Sakae| Takahashi, Sumio| |
|---|---|
| Published Date | 2011-05 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume27 |
| Content Type | Journal Article |
