start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=1 end-page=6 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=2020 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of Patient Positioning during Digital Tomosynthesis and Reconstruction Algorithms for Ilizarov Frames: A Phantom Study en-subtitle= kn-subtitle= en-abstract= kn-abstract=Aim: Metallic components from circular external fixators, including the Ilizarov frame, cause artefacts on X-rays and obstruct clear visualisation of bone detail. We evaluated the ability of tomosynthesis to reduce interference on radiographs caused by metal artefacts and developed an optimal image acquisition method for such cases.
Materials and methods: An Ilizarov frame phantom was constructed using rods placed on the bone for the purpose to evaluate the benefits of tomosynthesis. Distances between the rod and bone and the angle between the rod and X-ray tube orbit were set at three different levels. Filtered backprojection images were reconstructed using two different features of the reconstruction function: THICKNESS?? (CONTRAST4) and THICKNESS++ (METAL4); the first is suitable for improving contrast and the second is suitable for metal artefacts. The peak signal-to-noise ratio (PSNR) was used during image evaluation to determine the influence of the metallic rod on bone structure visibility.
Results: The PSNR increased as the angle between the metal rod and the X-ray tube orbit and the distance between the metallic rod and bone increased. The PSNR was larger when using THICKNESS?? (CONTRAST4) than when using THICKNESS++ (METAL4).
Conclusion: The optimal reconstruction function and image acquisition determined using the metallic rod in this study suggest that quality equal to that without the metallic rod can be obtained.
Clinical significance: We describe an optimised method for image acquisition without unnecessary acquisition repetition and unreasonable posture changes when the bone cannot be adequately visualised. en-copyright= kn-copyright= en-aut-name=AbeYuki en-aut-sei=Abe en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShimadaMakoto en-aut-sei=Shimada en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=EnokiTaisuke en-aut-sei=Enoki en-aut-mei=Taisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OmachiKumiko en-aut-sei=Omachi en-aut-mei=Kumiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=AbeShuji en-aut-sei=Abe en-aut-mei=Shuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University, kn-affil= affil-num=2 en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University, kn-affil= affil-num=3 en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University, kn-affil= affil-num=4 en-affil=Department of Educational Collaboration, Health and Safety Sciences, Osaka Kyoiku University kn-affil= affil-num=5 en-affil=Department of Radiology, Osaka General Medical Center, kn-affil= affil-num=6 en-affil=Department of Radiology, Osaka Women's and Children’s Hospital kn-affil= en-keyword=Digital tomosynthesis kn-keyword=Digital tomosynthesis en-keyword=Ilizarov, Metal artefacts kn-keyword=Ilizarov, Metal artefacts en-keyword=Metallic rod, Peak signal-to-noise ratio kn-keyword=Metallic rod, Peak signal-to-noise ratio en-keyword=X-ray kn-keyword=X-ray END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=5 article-no= start-page=415 end-page=422 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202010 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Oblique Surface Dose Calculation in High-Energy X-ray Therapy en-subtitle= kn-subtitle= en-abstract= kn-abstract=During radiation therapy, incident radiation oblique to the skin surface is high and may cause severe skin damage. Understanding the dose of radiation absorbed by the skin is important for predicting skin damage due to radiation. In this study, we used a high-energy (4 MV) X-ray system and an optically stimulated luminescence dosimeter (OSLD) that was developed for personal exposure dosimetry. We determined the dose variation and angular dependence, which are the characteristics of a small OSLD required to derive the calculation formula for the oblique surface dose. The dose variation was determined using the coefficient of variation. The maximum coefficient of variation for 66 small-field OSLDs was 1.71%. The angular dependence, obtained from the dose ratio of the dosimeter in the vertical direction, had a maximum value of 1.37. We derived a new equation in which the oblique surface dose can be calculated within the error range of ?7.7-5.1%. en-copyright= kn-copyright= en-aut-name=NarihiroNaomasa en-aut-sei=Narihiro en-aut-mei=Naomasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OitaMasataka en-aut-sei=Oita en-aut-mei=Masataka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Health Sciences, Department of Radiological Technology, Okayama University kn-affil= affil-num=2 en-affil=Department of Graduate School of Interdisciplinary Sciences and Engineering in Health Systems, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Health Sciences, Department of Radiological Technology, Okayama University kn-affil= en-keyword=optically stimulated luminescent dosimeter kn-keyword=optically stimulated luminescent dosimeter en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=oblique surface dose kn-keyword=oblique surface dose en-keyword=high-energy X-ray therapy kn-keyword=high-energy X-ray therapy en-keyword=angular dependence kn-keyword=angular dependence END start-ver=1.4 cd-journal=joma no-vol=40 cd-vols= no-issue=7 article-no= start-page=703 end-page=710 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=201907 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Diagnostic value of ventilation/perfusion single-photon emission computed tomography/computed tomography for bronchiolitis obliterans syndrome in patients after lung transplantation en-subtitle= kn-subtitle= en-abstract= kn-abstract=OBJECTIVE:
To evaluate the diagnostic value of function volume/morphological volume ratio calculated from ventilation/perfusion single-photon emission computed tomography/computed tomography in distinguishing the lungs with bronchiolitis obliterans syndrome (BOS) from the lungs without this syndrome after lung transplantation and to assess its relationship with spirometry parameters.
MATERIALS AND METHODS:
We retrospectively identified 84 consecutive lung transplant recipients and 13 donors who underwent ventilation/perfusion single-photon emission computed tomography/computed tomography. Differences in the function volume/morphological volume ratio of unilateral lungs were tested for significance between the lungs with and without BOS. Receiver operating characteristics and correlations between function volume/morphological volume ratios of bilateral lungs and forced expiratory volume in 1?s, forced vital capacity, and total lung capacity were analyzed.
RESULTS:
The function volume/morphological volume ratios of ventilation and perfusion images of unilateral lungs were significantly lower in lungs with BOS (each P<0.0001). The area under the curve values of ventilation and perfusion images were 0.97 and 0.99, respectively. Significant correlations were identified between the function volume/morphological volume ratios of ventilation and perfusion images and forced expiratory volume in 1?s (r=0.54, P<0.0001 and r=0.45, P<0.0001, respectively). The function volume/morphological volume ratio of ventilation image had a significantly weak correlation with forced vital capacity.
CONCLUSION:
The function volume/morphological volume ratio enables a semiquantitative assessment of ventilation and perfusion lung functions and is useful for diagnosing BOS after lung transplantation. en-copyright= kn-copyright= en-aut-name=NakashimaMasahiro en-aut-sei=Nakashima en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShinyaTakayoshi en-aut-sei=Shinya en-aut-mei=Takayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OtoTakahiro en-aut-sei=Oto en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OkawaTomoyo en-aut-sei=Okawa en-aut-mei=Tomoyo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= Department of Radiological Technology, Graduate School of Health Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Pediatric Radiology, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Organ Transplant Center, Okayama University Hospital kn-affil= affil-num=4 en-affil=Department of Organ Transplant Center, Okayama University Hospital kn-affil= affil-num=5 en-affil= Department of Radiological Technology, Graduate School of Health Sciences, Okayama University kn-affil= en-keyword=bronchiolitis obliterans syndrome kn-keyword=bronchiolitis obliterans syndrome en-keyword=forced expiratory volume kn-keyword=forced expiratory volume en-keyword=function volume kn-keyword=function volume en-keyword= lung transplantation kn-keyword= lung transplantation en-keyword=morphological volume kn-keyword=morphological volume END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=4 article-no= start-page=593 end-page=600 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=201707 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Accuracy assessment methods of tissue marker clip placement after 11-gauge vacuum-assisted stereotactic breast biopsy: comparison of measurements using direct and conventional methods en-subtitle= kn-subtitle= en-abstract= kn-abstract=BACKGROUND:　 The objective of the study was to compare direct measurement with a conventional method for evaluation of clip placement in stereotactic vacuum-assisted breast biopsy (ST-VAB) and to evaluate the accuracy of clip placement using the direct method.　 METHODS:　 Accuracy of clip placement was assessed by measuring the distance from a residual calcification of a targeted calcification clustered to a clip on a mammogram after ST-VAB. Distances in the craniocaudal (CC) and mediolateral oblique (MLO) views were measured in 28 subjects with mammograms recorded twice or more after ST-VAB. The difference in the distance between the first and second measurements was defined as the reproducibility and was compared with that from a conventional method using a mask system with overlap of transparent film on the mammogram. The 3D clip-to-calcification distance was measured using the direct method in 71 subjects.　 RESULTS:　 The reproducibility of the direct method was higher than that of the conventional method in CC and MLO views (P = 0.002, P < 0.001). The median 3D clip-to-calcification distance was 2.8 mm, with an interquartile range of 2.0-4.8 mm and a range of 1.1-36.3 mm.　 CONCLUSION:　 The direct method used in this study was more accurate than the conventional method, and gave a median 3D distance of 2.8 mm between the calcification and clip. en-copyright= kn-copyright= en-aut-name=YatakeHidetoshi en-aut-sei=Yatake en-aut-mei=Hidetoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SawaiYuka en-aut-sei=Sawai en-aut-mei=Yuka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NishiToshio en-aut-sei=Nishi en-aut-mei=Toshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakanoYoshiaki en-aut-sei=Nakano en-aut-mei=Yoshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishimaeAyaka en-aut-sei=Nishimae en-aut-mei=Ayaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KatsudaToshizo en-aut-sei=Katsuda en-aut-mei=Toshizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YabunakaKoichi en-aut-sei=Yabunaka en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=InajiHideo en-aut-sei=Inaji en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Department of Radiology, Breast Cancer Center, Kaizuka City Hospital kn-affil= affil-num=2 en-affil= Department of Radiology, Breast Cancer Center, Kaizuka City Hospital kn-affil= affil-num=3 en-affil= Department of Breast Surgery, Breast Cancer Center, Kaizuka City Hospital kn-affil= affil-num=4 en-affil=Department of Breast Surgery, Breast Cancer Center, Kaizuka City Hospital kn-affil= affil-num=5 en-affil=Department of Breast Surgery, Breast Cancer Center, Kaizuka City Hospital kn-affil= affil-num=6 en-affil=Department of Health Science, Osaka Butsuryo University kn-affil= affil-num=7 en-affil=Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, University of Tokyo kn-affil= affil-num=8 en-affil= Graduate School of Health Science, Okayama University kn-affil= affil-num=9 en-affil= Department of Breast Surgery, Breast Cancer Center, Kaizuka City Hospital kn-affil= en-keyword=Breast cancer kn-keyword=Breast cancer en-keyword=Direct methods kn-keyword=Direct methods en-keyword=Mammography kn-keyword=Mammography en-keyword=Mask methods kn-keyword=Mask methods en-keyword=Stereotactic vacuum assisted biopsy kn-keyword=Stereotactic vacuum assisted biopsy END start-ver=1.4 cd-journal=joma no-vol=66 cd-vols= no-issue=1 article-no= start-page=17 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=201202 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Measurements and Evaluation of Proximal Femoral Bone Mineral Density with Dual Energy X-ray Absorptiometry en-subtitle= kn-subtitle= en-abstract= kn-abstract=Proximal femoral bone mineral density (BMD) can be measured by dual energy X-ray absorptiometry method in the neck, trochanter, intertrochanter, total and Ward's triangle area. Ward's triangle area of the proximal femur is a smaller area to measure than the others, and the position varies, depending on the status of inner rotation of the target leg. In this study, the measurements of the proximal femoral BMD in women were carried out on the neck, trochanter, intertrochanter, total and Ward's triangle area with the, subjects' legs turned 15 degrees toward the inside. The Ward's BMD were measured using Ward's cognitive method, in which the measured BMD were compared among age groups of 50-59, 60-69, 70-79 and 80-89 to determine whether this process could reveal decreased femoral BMD in elderly women. The correlation between BMD and age was tested using the Pearson correlation coefficient. In all measured parts, the BMD of women age 50-59 were significantly higher than those of women age 80-89. The correlations between BMD and age were negative in all measured parts, and the most negative correlation was between age and Ward's BMD. The study using Ward's cognitive method showed an inverse correlation between Ward's BMD and age in women. en-copyright= kn-copyright= en-aut-name=HayashidaKeiichi en-aut-sei=Hayashida en-aut-mei=Keiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KatsudaToshizo en-aut-sei=Katsuda en-aut-mei=Toshizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoKenyu en-aut-sei=Yamamoto en-aut-mei=Kenyu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SuesadaYasuhide en-aut-sei=Suesada en-aut-mei=Yasuhide kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ShibataMoeko en-aut-sei=Shibata en-aut-mei=Moeko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AzumaMasami en-aut-sei=Azuma en-aut-mei=Masami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University affil-num=2 en-affil= kn-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University affil-num=3 en-affil= kn-affil=Seikeikai 2-Gakuin affil-num=4 en-affil= kn-affil=Osaka Cancer Prevention and Detection Center affil-num=5 en-affil= kn-affil=Department of Radiology, Meiwa Hospital affil-num=6 en-affil= kn-affil=Department of Radiology, Meiwa Hospital affil-num=7 en-affil= kn-affil=Osaka Kyoiku University en-keyword=proximal femoral BMD kn-keyword=proximal femoral BMD en-keyword=dual energy X-ray absorptiometry kn-keyword=dual energy X-ray absorptiometry en-keyword=Ward?s BMD kn-keyword=Ward?s BMD en-keyword=Ward?s cognitive method kn-keyword=Ward?s cognitive method END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=3 article-no= start-page=189 end-page=196 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=201006 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Infant Hip Joint Diagnostic Support System Based on Clinical Manifestations in X-ray Images en-subtitle= kn-subtitle= en-abstract= kn-abstract=Plain X-ray radiography is frequently used for the diagnosis of developmental dislocation of the hip (DDH). The aim of this study was to construct a diagnostic support system for DDH based on clinical findings obtained from the X-ray images of 154 female infants with confirmed diagnoses made by orthopedists. The data for these subjects were divided into 2 groups. The Min-Max method of nonlinear analysis was applied to the data from Group 1 to construct the diagnostic support system based on the measurement of 4 items in X-ray images:the outward displacement rate, upward displacement rate, OE angle, and alpha angle. This system was then applied to the data from Group 2, and the results were compared between the 2 groups to verify the reliability of the system. We obtained good results that matched the confirmed diagnoses of orthopedists with an accuracy of 85.9%. en-copyright= kn-copyright= en-aut-name=HondaMitsugi en-aut-sei=Honda en-aut-mei=Mitsugi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AritaSeizaburo en-aut-sei=Arita en-aut-mei=Seizaburo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitaniShigeru en-aut-sei=Mitani en-aut-mei=Shigeru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=InamuraKeiji en-aut-sei=Inamura en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University affil-num=2 en-affil= kn-affil=Faculty of Life and Medical Sciences, Doshisha University affil-num=3 en-affil= kn-affil=Department of Bone and Joint Surgery, Kawasaki Medical School affil-num=4 en-affil= kn-affil=Radiological Technology, Graduate School of Health Sciences, Okayama University affil-num=5 en-affil= kn-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Central Division of Radiology, Okayama University Hospital affil-num=7 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences en-keyword=X-ray image kn-keyword=X-ray image en-keyword=developmental dislocation of the hip kn-keyword=developmental dislocation of the hip en-keyword=acetabular dysplasia kn-keyword=acetabular dysplasia en-keyword=radiographic findings kn-keyword=radiographic findings en-keyword=nonlinear multivariate analysis kn-keyword=nonlinear multivariate analysis en-keyword=infant hip joint diagnostic support system kn-keyword=infant hip joint diagnostic support system END start-ver=1.4 cd-journal=joma no-vol=58 cd-vols= no-issue=1 article-no= start-page=7 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=200402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Functional evaluation of lung by Xe-133 lung ventilation scintigraphy before and after lung volume reduction surgery (LVRS) in patients with pulmonary emphysema. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We evaluated the respiratory functions of patients with pulmonary emphysema who underwent lung volume reduction surgery (LVRS) by the mean transit time (MTT) with Xe-133 lung ventilation scintigraphy, forced expiration volume in 1 sec (FEV1.0), residual volume (RV), distance walked in 6 min (6-min walk), and the Hugh-Jones classification (H-J classification) before and after LVRS. In 69 patients with pulmonary emphysema (62 men, 7 women; age range, 47-75 years; mean age, 65.4 years +/- 6.1, preoperative H-J classification, III (two were II)-V) who underwent LVRS, all preoperative and postoperative parameters (MTT 3 weeks after LVRS and the others 3 months after LVRS) were judged statistically by the Wilcoxon signed-ranks test and Odds ratio. Every postoperative parameter was improved with a significant difference (P < 0.05) compared to preoperative parameters. MTT at 3 weeks after LVRS was not associated with %FEV1.0 and the H-J classification at 3 months after LVRS, but was associated with RV and a 6-min walk at 3 months after LVRS. MTT was useful for the clinical evalution of aerobic capability after LVRS.

en-copyright= kn-copyright= en-aut-name=KuroseTaichi en-aut-sei=Kurose en-aut-mei=Taichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OkumuraYoshihiro en-aut-sei=Okumura en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SatoShuhei en-aut-sei=Sato en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoYasuhiro en-aut-sei=Yamamoto en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AkakiShiro en-aut-sei=Akaki en-aut-mei=Shiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=AndoAkio en-aut-sei=Ando en-aut-mei=Akio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=DateHiroshi en-aut-sei=Date en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=ShimizuNobuyoshi en-aut-sei=Shimizu en-aut-mei=Nobuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=Okayama University affil-num=9 en-affil= kn-affil=Okayama University affil-num=10 en-affil= kn-affil=Okayama University affil-num=11 en-affil= kn-affil=Okayama University en-keyword=lung volume reduction surgery (LVRS) kn-keyword=lung volume reduction surgery (LVRS) en-keyword=respiratory functions kn-keyword=respiratory functions en-keyword=Xe-133 lung ventilation scintigraphy kn-keyword=Xe-133 lung ventilation scintigraphy en-keyword=pulmonary emphysema kn-keyword=pulmonary emphysema END start-ver=1.4 cd-journal=joma no-vol=58 cd-vols= no-issue=2 article-no= start-page=75 end-page=83 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=200404 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Differentiation of thyroid nodules using Tl-201 scintigraphy quantitative analysis and fine-needle aspiration biopsy. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We studied the differentiation of thyroid nodules using fine-needle aspiration biopsy (FNA) and Tl-201 scintigraphy quantitative analysis. One-hundred and thirty-one thyroid nodules were examined: 83 follicular lesions (58 benign and 25 malignant lesions) and 48 non-follicular lesions (8 benign and 40 malignant lesions). During Tl-201 scintigraphy examinations, an early and a delayed image were acquired 10 and 120 min after an intravenous injection, respectively. The T/N ratio (counts of nodular lesion/counts of contralateral normal thyroid tissue) of each image was calculated quantitatively. We assessed the ability of the Tl-201 scintigraphy and of the FNA analysis to differentiate benign and malignant lesions and determined the cut-off levels for the assays. For the follicular lesions, the area under the ROC (Receiver Operating Characteristic) curve (Az) for the Tl-201 scintigraphy data was greater than that for the FNA data. For the non-follicular lesions, the Az for the FNA data was greater than that for the Tl-201 scintigraphy data. We set cut-off levels at 1.370 for follicular lesions, and 1.070 for non-follicular lesions. The sensitivity and specificity were 76% and 82.7% for follicular lesions, and 90% and 87.5% for non-follicular lesions, respectively. The overall accuracy of the analysis was 84.0%.

en-copyright= kn-copyright= en-aut-name=YamamotoYasuhiro en-aut-sei=Yamamoto en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OkumuraYoshihiro en-aut-sei=Okumura en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SatoShuhei en-aut-sei=Sato en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MakiKumi en-aut-sei=Maki en-aut-mei=Kumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MukaiTakashi en-aut-sei=Mukai en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MifuneHirofumi en-aut-sei=Mifune en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AkakiShiro en-aut-sei=Akaki en-aut-mei=Shiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=Okayama University affil-num=9 en-affil= kn-affil=Okayama University affil-num=10 en-affil= kn-affil=Okayama University en-keyword=?thyroid nodules kn-keyword=?thyroid nodules en-keyword=fine-needle aspiration biopsy(FNA) kn-keyword=fine-needle aspiration biopsy(FNA) en-keyword=Tl-201scintigraphy kn-keyword=Tl-201scintigraphy END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=5 article-no= start-page=225 end-page=232 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=199910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of liver function parameters by Tc-99m-GSA using multivariate analysis: a study of 47 clinical cases. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

To investigate the correlation between nuclear medicine parameters determined by technetium-99m-DTPA-galactosyl-human serum albumin (Tc-99m-GSA) and liver function tests, canonical correlation analysis was performed. Tc-99m-GSA studies were performed on 47 patients with hepatocellular carcinoma (HCC) who had undergone transcatheter arterial embolization (TAE). The nuclear medicine parameters LU15, HH15 and LHL15, which are results of nuclear imaging tests, were chosen in combination with the following liver function tests: the serum bilirubin level (T.Bil), the serum albumin level (Alb), serum cholinesterase activity (Ch-E), the clearance rate of indocyanine green (KICG), the hepaplastin test (HPT) and the prothrombin time (PT). The canonical correlation coefficient was 0.7345 and the upper tail probability was 0.00167. A significant correlation was observed between the two sets of variables. The high structural coefficients of Ch-E, KICG and HPT indicated a close relationship with the nuclear medicine parameters, supporting the notion that these nuclear medicine parameters are useful for the estimation of liver damage. The structural coefficients of the nuclear medicine parameters were also high, with LU15 being a parameter as useful as both HH15 and LHL15. T.Bil may evaluate a liver function that is not measured by nuclear imaging techniques, so we should take T.Bil results into account before considering TAE.

en-copyright= kn-copyright= en-aut-name=SuzukiYasunori en-aut-sei=Suzuki en-aut-mei=Yasunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KohnoYoshihiro en-aut-sei=Kohno en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Fukuyama National Hospital affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=Technetium-99m-DTPA-galactosyl-human serum albumin kn-keyword=Technetium-99m-DTPA-galactosyl-human serum albumin en-keyword=hepatocellular carcinoma kn-keyword=hepatocellular carcinoma en-keyword=transcatheter arterial embolization kn-keyword=transcatheter arterial embolization en-keyword=multivariate analysis kn-keyword=multivariate analysis END start-ver=1.4 cd-journal=joma no-vol=47 cd-vols= no-issue=3 article-no= start-page=169 end-page=174 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=199306 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Hyperthermotherapy added to the multidisciplinary therapy for penile cancer. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We performed a long-term follow-up of 4 patients with penile cancer who underwent hyperthermotherapy from August 1985 until August 1992. Hyperthermia was applied using a frequency of 350 MHz with a waveguide applicator twice a week for 60 min each for an average of 9.5 times (varying from 6 to 13 times). The total heating time that the temperature of urethra could be kept above 42 degrees C, was 166 min on the average (ranging from 0 to 463 min). Two patients classified as stage I according to the Jackson classification and 1 patient classified as stage IV underwent combined radiotherapy and received an average radiation dose of 53 Gy (range, 40-70 Gy). Among these patients 2 underwent combined chemotherapy with bleomycin or peplomycin. Malignant cells disappeared posttherapeutically and in August 1992, after an average of 5 years and 9 months (varying from 4 years 6 months to 6 years 10 months), the patients were free of recurrences. The one patient on stage IV had extensive invasion of the abdominal wall, but still recovered completely. One patient on stage III underwent combined chemotherapy and hyperthermotherapy, but heating had obviously been insufficient. There was a residue of malignant cells after the treatment and we performed a penectomy. Regarding functional preservation of the penis a multidisciplinary therapy incorporating hyperthermotherapy can be expected to increase the curativity. This indicates that it could induce in an advanced case, where an operation would be difficult, complete remission.

en-copyright= kn-copyright= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TsushimaTomoyasu en-aut-sei=Tsushima en-aut-mei=Tomoyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NasuYasutomo en-aut-sei=Nasu en-aut-mei=Yasutomo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AsaumiJunichi en-aut-sei=Asaumi en-aut-mei=Junichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishikawaKoji en-aut-sei=Nishikawa en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=GaoXian Shu en-aut-sei=Gao en-aut-mei=Xian Shu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MakihataEiichi en-aut-sei=Makihata en-aut-mei=Eiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OhmoriHiroyuki en-aut-sei=Ohmori en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=Okayama Univresity affil-num=9 en-affil= kn-affil=Okayama University affil-num=10 en-affil= kn-affil=Okayama University affil-num=11 en-affil= kn-affil=Okayama University affil-num=12 en-affil= kn-affil=Okayama University affil-num=13 en-affil= kn-affil=Okayama University en-keyword=penile cancer kn-keyword=penile cancer en-keyword=hyperthermia kn-keyword=hyperthermia en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=chemotherapy kn-keyword=chemotherapy END start-ver=1.4 cd-journal=joma no-vol=47 cd-vols= no-issue=2 article-no= start-page=117 end-page=120 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=199304 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Multivariate analysis of magnetic resonance imaging of focal hepatic lesions. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A total of 124 lesions from 1 to 6cm in diameter, including 31 cavernous hemangiomas, 32 metastases and 61 hepatocellular carcinomas (HCC) were analyzed to study the usefulness of magnetic resonance imaging (MRI) at 0.5 Tesla to differentiate focal hepatic lesions on the basis of qualitative criteria. Each focal hepatic lesion was assessed for shape, internal architecture and signal intensity relative to normal liver parenchyma. While all cavernous hemangiomas and metastases except one lesion could be detected, detection rate of HCC was significantly inferior to that of the other two diseases. A tumor capsule and a hyperintense focus on T1-weighted images were demonstrated in only HCC lesions in strong contrast with the other two diseases; however, metastases with slow-growing characteristics or subacute hematoma may appear as similar images. Cavernous hemangiomas appeared markedly hyperintense on T2-weighted images in 23 of 31 lesions, but one metastasis and one HCC had similar images. A multivariate analysis of several MRI resulted in the following mean discriminant scores: cavernous hemangioma, -1.2652; metastasis, 0.1830; and HCC, 0.7138. It appeared to be possible to differentiate the three diseases with 84.4 percent accuracy.

en-copyright= kn-copyright= en-aut-name=FujishimaMamoru en-aut-sei=Fujishima en-aut-mei=Mamoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SuemitsuIchizou en-aut-sei=Suemitsu en-aut-mei=Ichizou kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SeiTetsurou en-aut-sei=Sei en-aut-mei=Tetsurou kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama Univeristy affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University en-keyword=magnetic resonance imaging kn-keyword=magnetic resonance imaging en-keyword=liver neoplasms kn-keyword=liver neoplasms en-keyword=multivariate analysis kn-keyword=multivariate analysis END start-ver=1.4 cd-journal=joma no-vol=47 cd-vols= no-issue=4 article-no= start-page=249 end-page=254 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=199308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Hyperthermotherapy for postoperative local recurrences of rectal cancer. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Between November 1984 and August 1992 we used hyperthermotherapy in six cases of local recurrence of rectal cancer. Hyperthermotherapy was performed on the average 8.7 times (range: 3-18) for each patient for 60 min each. All patients underwent combined radiotherapy and received a mean radiation dose of 42.5 Gy (range: 9-60 Gy). Five patients underwent heating within 1 h after irradiation and one patient simultaneously with the irradiation. Four patients underwent combined chemotherapy and two patients immunotherapy. Before the treatment all patients had painful lesions, but pain decreased posttherapeutically in five patients. Performance status improved in two patients. High carcinoembryonic antigen levels prior to the therapy in four patients decreased in all cases after treatment. Posttherapeutical computed tomograms revealed only minor response or no changes. After the treatment, four patients died of exacerbations of recurrent tumors and one patient of distant metastases. The patient who underwent simultaneous radiohyperthermotherapy is presently alive, in August 1992, 38 months after initiation of the treatment. The 50% survival time after initiation of the treatment was 25 months (range: 10-38 months). Hyperthermotherapy combined with radiotherapy, chemotherapy and/or immunotherapy was useful for the alleviation of pain in patients who developed local recurrence after surgery, and improved survival after recurrences can be expected.

en-copyright= kn-copyright= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HizutaAkio en-aut-sei=Hizuta en-aut-mei=Akio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IwagakiHiromi en-aut-sei=Iwagaki en-aut-mei=Hiromi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MakihataEiichi en-aut-sei=Makihata en-aut-mei=Eiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=AsaumiJunichi en-aut-sei=Asaumi en-aut-mei=Junichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NishikawaKoji en-aut-sei=Nishikawa en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=GaoXian Shu en-aut-sei=Gao en-aut-mei=Xian Shu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NakagawaTomio en-aut-sei=Nakagawa en-aut-mei=Tomio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=Okayama University affil-num=9 en-affil= kn-affil=Okayama University affil-num=10 en-affil= kn-affil=Okayama University affil-num=11 en-affil= kn-affil=Okayama University affil-num=12 en-affil= kn-affil=Okayama University affil-num=13 en-affil= kn-affil=Okayama University affil-num=14 en-affil= kn-affil=Okayama University en-keyword=rectal cancer kn-keyword=rectal cancer en-keyword=local recurrence kn-keyword=local recurrence en-keyword=hyperthermia kn-keyword=hyperthermia en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=chemotherapy kn-keyword=chemotherapy END start-ver=1.4 cd-journal=joma no-vol=48 cd-vols= no-issue=5 article-no= start-page=283 end-page=288 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199410 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Quantitative measurement of portal blood flow by magnetic resonance phase contrast: comparative study of flow phantom and Doppler ultrasound in vivo. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A non-invasive method for measuring portal blood flow by magnetic resonance (MR) phase contrast was evaluated in a flow phantom and 20 healthy volunteers. In a flow phantom study, the flow volumes and mean flow velocities measured by MR phase contrast showed close correlations with those measured by electromagnetic flowmetry. In 20 healthy volunteers, the cross-sectional areas, flow volumes and mean flow velocities measured by MR phase contrast correlated well with those measured by the Doppler ultrasound method. Portal blood flow averaged during the imaging time could be measured under natural breathing conditions by using a large number of acquisitions without the limitations imposed on the Doppler ultrasound method. MR phase contrast is considered to be useful for the non-invasive measurement of portal blood flow.

en-copyright= kn-copyright= en-aut-name=TsunodaMasatoshi en-aut-sei=Tsunoda en-aut-mei=Masatoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HamazakiKeisuke en-aut-sei=Hamazaki en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama Rousai Hospital affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama Univeristy affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University en-keyword=portal blood flow kn-keyword=portal blood flow en-keyword=magnetic resonance imaging kn-keyword=magnetic resonance imaging en-keyword=phase contrast kn-keyword=phase contrast END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=9-10 article-no= start-page=1015 end-page=1024 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Alteration of mitochondrial functions by lipid peroxidation and inhibition by biscoclaurine alkaloid kn-title=脂質過酸化反応によるミトコンドリァ機能の変化とビスコクラウリン型アルカロイドによる阻害作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=During investigation of the changes in mitochondrial function accompanying lipid peroxidation, it was found that a biscoclaurine alkaroid protected their functional changes. The results obtained were as follows: 1) Fe(2+) induces lipid peroxidation of isolated mitochondria, resulting in deterioration of oxidative phosphorylation. 2) This deterioration relates to alteration in ion compartmentation of the mitochondrial membrane and an increase in latent ATPase activity. 3) This deterioration by Fe(2+) in ion compartmentation of mitochondrial membrane is strongly protected by a biscoclaurine alkaloid, cepharanthine. 4) Cepharanthine also inhibits the mitochondrial. lipid peroxidation induced by Fe(2+). 5) The protective effect of cepharanthine against deterioration in mitochondrial functions caused by Fe(2+) depends on its inhibitive action on lipid peroxidation as well as on its membrane stabilizing action. 6) Cepharanthine inhibits the lipid peroxidation of soybean lecithine liposomes by (60)Co-irradiation. 7) The action of cepharanthine described above is common to head to head type of biscoclaurin alkaloids which have diether bonds. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=3 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=4 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=5 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=6 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=8 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=9 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=10 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=11 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=12 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=13 ORCID= en-aut-name=ShiraishiNoriyuki en-aut-sei=Shiraishi en-aut-mei=Noriyuki kn-aut-name=白石則之 kn-aut-sei=白石 kn-aut-mei=則之 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=高知医科大学生物学教室 en-keyword=Lipid Peroxidation kn-keyword=Lipid Peroxidation en-keyword=Cepharanthine (Biscoclaurine Alkaloid) kn-keyword=Cepharanthine (Biscoclaurine Alkaloid) en-keyword=Mitochondrial Function kn-keyword=Mitochondrial Function END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=7-8 article-no= start-page=701 end-page=708 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Multiple polypoid filling defects of the duodenal bulb kn-title=十二指腸球部多発陰影欠損について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Multiple polypoid filling defects of the duodenal bulb are infrequently encountered. Two cases of multiple filling defects of the duodenal bulb are reported in this paper. Case 1. A 42 year old female complained of abdominal fullness and epigastralgia. On examination, generalized peripheral lymphadenopathy and marked hepatosplenomegaly were noted. Cervical lymphnode biopsy revealed a diffuse, poorly-differanciated lymphocytic lymphoma. X-ray examination of the gastrointestinal tract showed multiple filling defects localized at the duodenal bulb. Endoscopy disclosed multiple well-defined protrusions with small mucosal ulceration over the the whole circumference of the duodenal wall. Case 2. A 36 year old female had no subjective symptoms. At gastric mass screening, numerous polypoid elevations of the duodenal bulb were pointed out. Detailed gastrointestinal x-ray examination showed numerous, tiny, round polypoid nodules localized at the duodenal bulb. These nodules were 2-3mm in size with no mucosal ulceration. The endoscopic biopsy specimen revealed lymphoid hyperplasia of the duodenal bulb. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=2 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=3 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=4 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=5 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= en-aut-name=HayashiKyoichi en-aut-sei=Hayashi en-aut-mei=Kyoichi kn-aut-name=林恭一 kn-aut-sei=林 kn-aut-mei=恭一 aut-affil-num=11 ORCID= en-aut-name=TakaokaKazuko en-aut-sei=Takaoka en-aut-mei=Kazuko kn-aut-name=高岡和子 kn-aut-sei=高岡 kn-aut-mei=和子 aut-affil-num=12 ORCID= en-aut-name=OshimaYukiko en-aut-sei=Oshima en-aut-mei=Yukiko kn-aut-name=大島由起子 kn-aut-sei=大島 kn-aut-mei=由起子 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部第II内科学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部第II内科学教室 affil-num=13 en-affil= kn-affil=三菱水島病院内科 en-keyword=Duodenal bulb kn-keyword=Duodenal bulb en-keyword=multiple polypoid nodules kn-keyword=multiple polypoid nodules END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=1-2 article-no= start-page=63 end-page=78 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Study of CT-diagnosis for pancreatic diseases kn-title=膵疾患におけるCT診断 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The diagnosis of pancreatic diseases is difficult and examination techniques such as hypo tonic duodenography, ERSP, and PTC have been used to facilitate this. Computerized tomography (CT) has recently been introduced for the diagnosis of abdominal organs, and grea hopes were held for its application in pancreatic disease. However, according to reports bases on numerous clinical experiments, it is concluded that its value is not so high as expected Therefore, under present conditions, we are obliged to depend on other diagnostic technique which require great skill and cause pain to patients. This report deals with investigation o the image in cases we have experienced. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=2 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=3 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=5 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=6 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本眞 kn-aut-sei=木本 kn-aut-mei=眞 aut-affil-num=9 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=10 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=11 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=12 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=computed tomography kn-keyword=computed tomography en-keyword=Pancreas kn-keyword=Pancreas END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=9-10 article-no= start-page=819 end-page=826 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19861031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation of serum CA125 levels in gynecological disease patients kn-title=婦人科疾患におけるCA125値の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Since Bast et. al. reported that patients with ovarian carcinoma had elevated levels of CA125 in serum, the attention has been paid to CA125 in serum as a tumor maker. Serum CA125 levels in 88 patients with gynecological disease were measured. Among 15 patients with malignant ovarian tumor, CA125 values were above 35 U/ml in 80% , and above 65 U/ml in 73% , of serum samples assayed. By increasing the values of CA125 considered normal from 35 to 65 U/ml, the positive rate of benign ovarian tumor and carcinoma of the uterus was markedly reduced. Therefore, it was more efficient as a screening test for gynecological disease that the value of CA125 considered abnormal be above 65 U/ml. Serum CA125 levels were correlated with efficacy of therapy and the clinical course. en-copyright= kn-copyright= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=3 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=4 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=5 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=6 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=7 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=8 ORCID= en-aut-name=AkamatsuNobuo en-aut-sei=Akamatsu en-aut-mei=Nobuo kn-aut-name=赤松信雄 kn-aut-sei=赤松 kn-aut-mei=信雄 aut-affil-num=9 ORCID= en-aut-name=SekibaKaoru en-aut-sei=Sekiba en-aut-mei=Kaoru kn-aut-name=関場香 kn-aut-sei=関場 kn-aut-mei=香 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 en-keyword=CA 125 kn-keyword=CA 125 en-keyword=tumor marker kn-keyword=tumor marker en-keyword=malignant ovarian tumor kn-keyword=malignant ovarian tumor END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=3-4 article-no= start-page=271 end-page=287 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19840430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Increase in metallothionein content in rat tissues induced by X-irradiation kn-title=X線照射によるラット臓器中のメタロチオネインの変動について en-subtitle= kn-subtitle= en-abstract=The amount of metallothionein in rat liver and kidney was increased 72hr after irradiation by a high dose of X-irradiation (2,000 rad), but in other tissues the amount of metallothionein was not increased. An increase in metallothionein contents in rat liver and kidney was induced 72hr after irradiation when rats were exposed to a single dose between 1,500 and 3,000 rad. Below a single 1,000-rad dose, the increase in metallothionein content was not observed. An increase in the metallothionein content in the liver was observed 6hr after irradiation (2,000 rad). In kidney, the increase in the metallothionein content was observed 24hr after irradiation. Although the zinc content in serum did not change significantly after irradiation (2,000 rad), the zinc content of the albumin fraction decreased slightly. kn-abstract=(1)ラット肝Metallothioneinが増加する2000rad, 72時間後にMTの増加が認められるのは,腎臓のみで他の臓器(心臓,肺,脾臓,赤血球,血漿)では認められなかった.(2)肝,腎臓のMTの照射線量に対する増加には差が認められなかった.(3)照射後の経時的変化では,肝臓が6時間からその増加が認められるのに対して,腎臓では, 24時間と大きな違いが認められた.(4)照射後の血清亜鉛量に低下傾向は,認められないが, Sephacryl S-300のゲル濾過の結果では, Albumin分画の亜鉛量に低下傾向が認められ,血清亜鉛に質的変化が生じていることが示唆された. en-copyright= kn-copyright= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=メタロチオネイン kn-keyword=メタロチオネイン en-keyword=肝臓 kn-keyword=肝臓 en-keyword=腎臓 kn-keyword=腎臓 en-keyword=X線 kn-keyword=X線 en-keyword=血清 kn-keyword=血清 END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=9-10 article-no= start-page=823 end-page=831 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19851030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation of serum ferritin levels in primary lung cancer patients with radiation therapy Comparing with serum CEA levels kn-title=放射線治療を施行した原発性肺癌患者における血清フェリチン値の臨床的評価 ―血清CEA値と比較して― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum ferritin and serum carcinogenic embryonic antigen (CEA) levels in 153 patients (male: 112, female: 41) with primary lung cancer were simultaneously measured and compared with the histological type, clinical stage and clinical course. No correlation between serum ferritin and CEA levels was found. A higher percentage of positive test results for both serum ferritin and CEA was associated with advanced stages and metastasis in other organs. From the point of view of histological classification, high ferritin levels were mainly found in the patients with small-cell types of cancer. In contrast, high CEA levels were found in patients with adenocarcinoma. Therefore, the measurement of serum ferritin was not efficient as a screening test for lung cancer. Serum ferritin levels were, however, correlated with the efficacy of therapy and the clinical course. en-copyright= kn-copyright= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=3 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=4 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=5 ORCID= en-aut-name=SatohNobuo en-aut-sei=Satoh en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=6 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=7 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=8 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=9 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=10 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=11 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=12 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=国立療養所山陽荘病院放射線科 en-keyword=原発性肺癌 kn-keyword=原発性肺癌 en-keyword=血清フェリチン値 kn-keyword=血清フェリチン値 en-keyword=血清CEA値 kn-keyword=血清CEA値 END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=3-4 article-no= start-page=323 end-page=330 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19860430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Calcification of vertebral arteries of comparison of CT findings and clinical symptoms kn-title=椎骨動脈の石灰化 CT像と臨床症状との対比 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We analyzed calcifications in 557 computed tomography films of the head. Adnormal findings of calcification of vertebral arteroes were obrained in 36 of the 577 cases. In the 36 cases, vertigo was observed in 24 cases (66.7%), and brain atrophy in 10 cases (27.2%). The calcification of vertebral arteries (arteriosclerosis) correlated significantly with vertigo. Patients with vertigo should be examined by computed tomography for calcification of vertebral arteries at the level of the foramen magnum. en-copyright= kn-copyright= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=3 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=4 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=5 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=6 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=7 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=8 ORCID= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=9 ORCID= en-aut-name=ShimizuMitsuharu en-aut-sei=Shimizu en-aut-mei=Mitsuharu kn-aut-name=清水光春 kn-aut-sei=清水 kn-aut-mei=光春 aut-affil-num=10 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=11 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=12 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=13 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=国立療養所山陽荘病院 en-keyword=head CT kn-keyword=head CT en-keyword=extrapyramidal symptoms kn-keyword=extrapyramidal symptoms en-keyword=vertebral arterial calcification kn-keyword=vertebral arterial calcification END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=101 end-page=112 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Early clinical experience with NMR-CT kn-title=NMR-CTの初期臨床経験 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have used an NMR-CT scanner clinically since August 1 1984. We report herein the operating pulse sepuences, and present 5 cases of 226 cases that we have examined. From our clinical experience during the past four months, we describe the advantages and disadvantages of NMR-CT. The advantages are that: 1) it is possible to recognize blood vessels without contrast materials and to evaluate the blood flow 2) there are neither bone nor air artifacts, and 3) it is possible to get the tomogram in any direction. The disadvantages are that: 1) the examination time is very long, 2) there are artifacts from ferromagnetic substances placed in the body, 3) when palse sequence is changed, images are different from each other, and 4) because of respiratory motion artifacts, the images of the chest and abdomen are inferior to those of other parts of the body. en-copyright= kn-copyright= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=1 ORCID= en-aut-name=SatoNobuo en-aut-sei=Sato en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=2 ORCID= en-aut-name=FujishimaMamoru en-aut-sei=Fujishima en-aut-mei=Mamoru kn-aut-name=藤島護 kn-aut-sei=藤島 kn-aut-mei=護 aut-affil-num=3 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=4 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=5 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=6 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=7 ORCID= en-aut-name=YamamotoHiromichi en-aut-sei=Yamamoto en-aut-mei=Hiromichi kn-aut-name=山本博道 kn-aut-sei=山本 kn-aut-mei=博道 aut-affil-num=8 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=9 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=10 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=11 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=12 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=13 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=14 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=15 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=15 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=nucler magnetic resonance kn-keyword=nucler magnetic resonance en-keyword=spin echo kn-keyword=spin echo en-keyword=inversion recovery kn-keyword=inversion recovery en-keyword=T(1) relaxation time kn-keyword=T(1) relaxation time en-keyword=T(2) relaxation time kn-keyword=T(2) relaxation time END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=91 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Difficulty in determining the extent of metastatic lesions in bone scintigrams: A case report. kn-title=骨転移放射線治療において骨シンチグラムで病巣範囲決定に問題があった2症例の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Radiation therapy for bone metastasis of malignant tumors is useful for reducing pain and is often used. Bone scintigraphy is useful for the early detection of bone metastasis and for staging, and is important in making plans for the irradiation of metastatic bone lesions. However, the images of metastatic bone lesions vary, so the irradiation field must be decided by comparison with plain films, computed tomography, and so on. en-copyright= kn-copyright= en-aut-name=UedaHiroyuki en-aut-sei=Ueda en-aut-mei=Hiroyuki kn-aut-name=上田裕之 kn-aut-sei=上田 kn-aut-mei=裕之 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=JyojaIkuo en-aut-sei=Jyoja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=3 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=4 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=5 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=6 ORCID= en-aut-name=SatoNobuo en-aut-sei=Sato en-aut-mei=Nobuo kn-aut-name=佐藤伸夫 kn-aut-sei=佐藤 kn-aut-mei=伸夫 aut-affil-num=7 ORCID= en-aut-name=NakamuraTetsuya en-aut-sei=Nakamura en-aut-mei=Tetsuya kn-aut-name=中村哲也 kn-aut-sei=中村 kn-aut-mei=哲也 aut-affil-num=8 ORCID= en-aut-name=HinoHiroyuki en-aut-sei=Hino en-aut-mei=Hiroyuki kn-aut-name=日野祐之 kn-aut-sei=日野 kn-aut-mei=祐之 aut-affil-num=9 ORCID= en-aut-name=KoyamaNaoki en-aut-sei=Koyama en-aut-mei=Naoki kn-aut-name=小山直樹 kn-aut-sei=小山 kn-aut-mei=直樹 aut-affil-num=10 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=11 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=bone scintigram kn-keyword=bone scintigram en-keyword=bone metastasis kn-keyword=bone metastasis en-keyword=radiation therapy kn-keyword=radiation therapy en-keyword=bone CT kn-keyword=bone CT END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=1-2 article-no= start-page=55 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Serum ferritin levels in hospital patients kn-title=各種疾患における血清フェリチン値の臨床的評価 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum ferritin levels were determined in 75 hematologic, 1205 malignant, and 538 benign diseases. In hematologic diseases the serum ferritin level was generally low in iron deficiency anemia, but high in hemochromatosis, aplastic anemia, and leukemia. In malignant diseases the serum ferritin concentration was increased remarkably in lung, liver, biliary, and urogential diseases and in malignant lymphoma. Among benign diseases hepatitis cases showed a tendency for high serum ferritin levels. Serum ferritin levels are influenced by various factors, and their careful evaluation may be essential for understanding of the underlining disease process. en-copyright= kn-copyright= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=3 ORCID= en-aut-name=TogamiIzumi en-aut-sei=Togami en-aut-mei=Izumi kn-aut-name=戸上泉 kn-aut-sei=戸上 kn-aut-mei=泉 aut-affil-num=4 ORCID= en-aut-name=ShirakamiToshiaki en-aut-sei=Shirakami en-aut-mei=Toshiaki kn-aut-name=白神敏明 kn-aut-sei=白神 kn-aut-mei=敏明 aut-affil-num=5 ORCID= en-aut-name=ShiraishiNoriyuki en-aut-sei=Shiraishi en-aut-mei=Noriyuki kn-aut-name=白石則之 kn-aut-sei=白石 kn-aut-mei=則之 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=血清フェリチン値 kn-keyword=血清フェリチン値 en-keyword=悪性腫瘍 kn-keyword=悪性腫瘍 en-keyword=radioimmunoassay kn-keyword=radioimmunoassay END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=9-10 article-no= start-page=951 end-page=957 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Results of radiotherapy for lung cancer patients kn-title=岡山大学放射線科入院患者における肺癌の放射線治療成績の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The results of radiotherapy were investigated in 49 patients with lung cancer admitted to the Department of Radiology, Okayama University Hospital. Of the 26 patients not undergoing surgery, the one-year survival rate was 100% in the stage I patients, 55% in the stage V patients and 56% in the stage W patients, and the two-year survival rate was 50% in the stage I patients, 0% in the stage V patients and 9% in the stage W patients. A significant difference in survival between patients irradiated with over 60 Gy and patients irradiated with less than 60 Gy was recognized among those not undergoing surgery. However, with respect to the frequency of local recurrence and distant metastases, a correlation with the irradiated dose was not demonstrated. Local recurrence and distant metastases were not observed in 5 of 6 patients who received preventive irradiation after curative surgery was conducted. Concerning 11 patients after non-curative surgery, local recurrence and distant metastases were recognized in 3 of them, and 7 of them showed a favourable outcome brought about by the irradiation after surgery as expected. In 6 patients with local recurrence after surgery, the survival period after radiotherapy was less than 13 months. en-copyright= kn-copyright= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=3 ORCID= en-aut-name=MimuraHidehumi en-aut-sei=Mimura en-aut-mei=Hidehumi kn-aut-name=三村秀文 kn-aut-sei=三村 kn-aut-mei=秀文 aut-affil-num=4 ORCID= en-aut-name=MitaniMasahiko en-aut-sei=Mitani en-aut-mei=Masahiko kn-aut-name=三谷政彦 kn-aut-sei=三谷 kn-aut-mei=政彦 aut-affil-num=5 ORCID= en-aut-name=NagayamaMasako en-aut-sei=Nagayama en-aut-mei=Masako kn-aut-name=永山雅子 kn-aut-sei=永山 kn-aut-mei=雅子 aut-affil-num=6 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=7 ORCID= en-aut-name=KajiMitsumasa en-aut-sei=Kaji en-aut-mei=Mitsumasa kn-aut-name=加地充昌 kn-aut-sei=加地 kn-aut-mei=充昌 aut-affil-num=8 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=肺癌 kn-keyword=肺癌 en-keyword=放射線治療 kn-keyword=放射線治療 en-keyword=治療成績 kn-keyword=治療成績 END start-ver=1.4 cd-journal=joma no-vol=99 cd-vols= no-issue=1-2 article-no= start-page=15 end-page=23 dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=19870228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radiotherapy of brain metastases from lung cancer kn-title=肺癌脳転移の放射線治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We studied the results of radiotherapy in 65 patients with brain metastases of lung cancer. In the 34 patients whose treatment consisted of radiotherapy alone, the median survival time was 164 days and the mean survival time was 210 days. Remission was achieved in 29 (85%) of these patients, indicating that radiotherapy was effective. A minimum radiation dose of 30 Gy was necessary to decrease neurological symptoms, and 40 Gy or more was considered to be desirable. Survival after radiotherapy appeared to be dependent largely on factors other than brain metastases such as the effectiveness of management of the primary lesion, the presence or the extent of metastases to other organs, and the patient's general condition. Our study suggests that greater efforts must be made for early detection and early treatment to achieve prolongation of as well as qualitative improvements in the survival time. en-copyright= kn-copyright= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=3 ORCID= en-aut-name=KashitaniNaoko en-aut-sei=Kashitani en-aut-mei=Naoko kn-aut-name=柏谷尚子 kn-aut-sei=柏谷 kn-aut-mei=尚子 aut-affil-num=4 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=5 ORCID= en-aut-name=YamamotoYoshio en-aut-sei=Yamamoto en-aut-mei=Yoshio kn-aut-name=山本淑雄 kn-aut-sei=山本 kn-aut-mei=淑雄 aut-affil-num=6 ORCID= en-aut-name=KanzakiNoriko en-aut-sei=Kanzaki en-aut-mei=Noriko kn-aut-name=神崎典子 kn-aut-sei=神崎 kn-aut-mei=典子 aut-affil-num=7 ORCID= en-aut-name=InoueNobuhiro en-aut-sei=Inoue en-aut-mei=Nobuhiro kn-aut-name=井上信浩 kn-aut-sei=井上 kn-aut-mei=信浩 aut-affil-num=8 ORCID= en-aut-name=NoriyasuToshiaki en-aut-sei=Noriyasu en-aut-mei=Toshiaki kn-aut-name=則安俊昭 kn-aut-sei=則安 kn-aut-mei=俊昭 aut-affil-num=9 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=10 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=11 ORCID= en-aut-name=MizutaAkihumi en-aut-sei=Mizuta en-aut-mei=Akihumi kn-aut-name=水田昭文 kn-aut-sei=水田 kn-aut-mei=昭文 aut-affil-num=12 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=13 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=brain metastases kn-keyword=brain metastases en-keyword=lung cancer kn-keyword=lung cancer END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue=2 article-no= start-page=105 end-page=112 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation was examined between mixed type barium sulfate suspensions "BarytgenHD" and "Barytgen" kn-title=混合粒子型硫酸バリウム｢バリトゲンHD｣の評価 en-subtitle= kn-subtitle= en-abstract=Both barium sulfate suspensions, Barytgen HD and Barytgen, had good stability. Although significant difference was not abserved in coating and visualization of gastric area, BarytgenHD showed better marginal visualization of gastric margin. Further study is needed to improve the visualization of sticky coating of gastric mucosa and many bubbles. BarytgenHD was easily to drink instead of high density barium sulfate suspensions. kn-abstract=混合粒子型硫酸バリウムバリトゲンHD200w/v%懸濁液について,バリトゲン160w/v%懸濁液と比較検討を行った｡懸濁液安定性は両者共良かった｡臨床評価においては,付着性,胃小区描出能は同程度であり,辺縁の描出能は良かったが凝集･ムラ付き,気泡は多くみられ懸濁液濃度について検討を加える必要があると考える｡飲み易さは,バリトゲンHD200w/v%懸濁液のほうが濃度が高いのにもかかわらず飲み易く好評であった｡ en-copyright= kn-copyright= en-aut-name=NobuharaEitarou en-aut-sei=Nobuhara en-aut-mei=Eitarou kn-aut-name=延原栄太朗 kn-aut-sei=延原 kn-aut-mei=栄太朗 aut-affil-num=1 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=2 ORCID= en-aut-name=ShibuyaKohichi en-aut-sei=Shibuya en-aut-mei=Kohichi kn-aut-name=澁谷光一 kn-aut-sei=澁谷 kn-aut-mei=光一 aut-affil-num=3 ORCID= en-aut-name=OguriNobuhiro en-aut-sei=Oguri en-aut-mei=Nobuhiro kn-aut-name=小栗宣博 kn-aut-sei=小栗 kn-aut-mei=宣博 aut-affil-num=4 ORCID= en-aut-name=AriokaTadashi en-aut-sei=Arioka en-aut-mei=Tadashi kn-aut-name=有岡匡 kn-aut-sei=有岡 kn-aut-mei=匡 aut-affil-num=5 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=6 ORCID= en-aut-name=MoriokaYasuki en-aut-sei=Morioka en-aut-mei=Yasuki kn-aut-name=森岡泰樹 kn-aut-sei=森岡 kn-aut-mei=泰樹 aut-affil-num=7 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=8 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=9 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=10 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=11 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院放射線科 affil-num=9 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院放射線科 affil-num=11 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=12 en-affil= kn-affil=岡山大学医学部附属病院放射線科 en-keyword=造影剤 (contorast media) kn-keyword=造影剤 (contorast media) en-keyword=硫酸バリウム (barium sulfate suspension) kn-keyword=硫酸バリウム (barium sulfate suspension) en-keyword=消化管検査 (barium examination) kn-keyword=消化管検査 (barium examination) END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue=1 article-no= start-page=41 end-page=48 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical evaluation of barium sulfate suspensions "Barytgen HD" - Second report - kn-title=混合粒子型硫酸バリウム｢バリトゲンHD｣の評価 ―第二報― en-subtitle= kn-subtitle= en-abstract=Barium sulfate suspensions in 200w/v% and 190w/v% had good stability. But in 180w/v% it had worse stability. Significant difference was not observed in coating, visualization of gastric margin and gastric area between in 200w/v% and 190w/v%. Barium sulfate suspensions in 190w/v% had less sticky coating of gastric mucosa and fewer bubbles than 200w/v%. Barium sulfate suspensions in 190w/v% was easiest density to drink. 190w/v% seems to be most adequate density in our study. kn-abstract=混合粒子型硫酸バリウム｢バリトゲンHD｣の懸濁液最適濃度について,検討を行った｡懸濁液安定性は,200w/v%と190w/v%は良好であったが,180w/v%は不良で臨床使用には不向きであると思われた｡臨床的評価において200w/v%と190w/v%は付着性,辺縁の描出能,胃小区描出能においては同程度であった｡200w/v%に多く見られた凝集･ムラ付き,気泡は,190w/v%では少なくなった｡飲み易さは,200w/v%,190w/v%とも飲み易いと評価されたが,190w/v%でより飲み易い傾向にあった｡バリトゲンHDの最適懸濁液濃度は,190w/v%であると思われる｡ en-copyright= kn-copyright= en-aut-name=NobuharaEitarou en-aut-sei=Nobuhara en-aut-mei=Eitarou kn-aut-name=延原栄太朗 kn-aut-sei=延原 kn-aut-mei=栄太朗 aut-affil-num=1 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=2 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=3 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=澁谷光一 kn-aut-sei=澁谷 kn-aut-mei=光一 aut-affil-num=4 ORCID= en-aut-name=MoriokaYasuki en-aut-sei=Morioka en-aut-mei=Yasuki kn-aut-name=森岡泰樹 kn-aut-sei=森岡 kn-aut-mei=泰樹 aut-affil-num=5 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=6 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院放射線科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院放射線科 affil-num=8 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院放射線科 en-keyword=造影剤 (contrast medium) kn-keyword=造影剤 (contrast medium) en-keyword=硫酸バリウム (barium sulfate suspension) kn-keyword=硫酸バリウム (barium sulfate suspension) en-keyword=消化管検査 (barium examination) kn-keyword=消化管検査 (barium examination) END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue=2 article-no= start-page=83 end-page=90 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Extended-cycle processによる乳房撮影用増感紙／フィルムシステムの画質改善 kn-title=Improvement of image quality on mammographic screen-film system by extended-cycle process en-subtitle= kn-subtitle= en-abstract=通常,extended-cycle processは処理時間が約210秒に延ばされた現像機のために使われる用語である｡乳房撮影に使われるような片面乳剤フィルムにおけるextended-cycle processは,フィルムコントラストを増し,感度をあげることが良く知られている｡そこで,本論文ではextended-cycle processにより低感度,高解像度システムの感度を上げ,どの程度解像度が維持されるかを調べた｡片面増感紙／片面フィルムの組合わせであるKonica M-100/CM-Hを低感度,高解像度システムとして用いた｡露光後のフィルムは現像温度30,32, 34度,処理時間210秒の異なる組合わせで現像処理した。一方,高感度システムとしてKonica M-200/CM-Hを用い,このフィルムは標準現像(34℃,90秒)された｡感度,増感紙／フイルムのぼけ,雑音に関して,特性曲線,MTF(modulation transfer function), WS(wiener spectrum)によってこれらのシステムを比較した｡さらにこれらのシステムにおける乳房写真の細部視覚評価のためにRM165ファントムを使用した｡その結果,M-100/CM-Hに対するextended-cycle process現像温度32, 34℃,処理時間210秒のextended-cycle processにおいて,高感度システムM-200/CM-Hと同等の感度を上げることが可能であった｡そのとき,コントラスト,MTF,視覚的検出能も高感度システムより向上した｡さらに,現像温度34℃,処理時間210秒では,被曝線量の低減が可能であった｡ kn-abstract=Extended-cycle process is the term used for a processor in which the processing time has been prolonged usually to approximate 210 seconds. It has been known that the extended-cycle process of some single-emulsion films as used for mammography may enhance film contrast and increase film speed. So the speed was increased in lower speed and higher resolution system than conventional systems by means of using the extended-cycle process in this paper. We investigated how much the resolution of the system was kept. A single screen-single emulsion combination, Konica M-100/CM-H was employed as a low speed and high resolution system. This film after exposure was processed in the different combinations of developing temperatures, 30, 32 and 34℃, and processing time of 210 seconds. On the other hand, Konica M-200/CM-H was employed as a high speed system. This film was processed in the standard-cycle processing (34℃, 90 seconds). Those systems were compared on contrast, speed, screen-film blur and noise by a characteristic curve, MTF (modulation transfer function) and WS (wiener spectrum). Furthermore, the RMI 165 phantom was used to evaluate visibility of mammographic details of these systems. As a result, in the extended-cycle process at the developing temperatures of 32 or 34°C and processing time of 210 seconds for M-100/CM-H, it was possible to increase the speed as much as the higher speed system, M-200/CM-H. Then the contrast, the MTF and the visibility were also improved as compared to the higher speed system. Furthermore patient dose could be reduced at the developing temperature of 34℃ and processing time of 210 seconds in M-100/CM-H. en-copyright= kn-copyright= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=1 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=3 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=4 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=KimuraFumie en-aut-sei=Kimura en-aut-mei=Fumie kn-aut-name=木村文江 kn-aut-sei=木村 kn-aut-mei=文江 aut-affil-num=7 ORCID= en-aut-name=KadohisaShigefumi en-aut-sei=Kadohisa en-aut-mei=Shigefumi kn-aut-name=門久繁文 kn-aut-sei=門久 kn-aut-mei=繁文 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=5 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=6 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=image quality kn-keyword=image quality en-keyword=mammography kn-keyword=mammography en-keyword=single screen-single emulsion film system kn-keyword=single screen-single emulsion film system en-keyword=high-resolution screen kn-keyword=high-resolution screen en-keyword=extended-cycle process kn-keyword=extended-cycle process END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=139 end-page=144 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radioprotective effect of epinephrine as a vasoconstrictor in mouse oral mucosa and scalp kn-title=マウス口腔粘膜および頭部皮膚に対する血管収縮剤エピネフリンの放射線防護効果の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Epinephrine is the most widely used vasoconstrictive drug. However, its radioprotective potential has not yet been studied for radiation-induced mucositis and dermatitis. Other vasoconstrictive drugs induce a radioprotective effect, but are not used because of their severe side effects. We studied the radioprotective effect of epinephrine on the oral mucosa and scalp of the mice. The radiation dose was 20Gy in a single fraction to the head of the mouse. In the group treated with epinephrine ointment, secretion from the oral cavity was slight, body wieght loss was less and hair loss was observed in fewer cases compared to those in the group without of epinephrine ointment. The mechanism is thought to be related to oxygenation. Epinephrine causes vasoconstriction, therefore the blood supply is lowered and the oxygen concentration in the tissue decline. In conclusion, epinephrine is considered to have potential as a radioprotective ointment for mucous membranes and skin. en-copyright= kn-copyright= en-aut-name=GaoXianshu en-aut-sei=Gao en-aut-mei=Xianshu kn-aut-name=高献書 kn-aut-sei=高 kn-aut-mei=献書 aut-affil-num=1 ORCID= en-aut-name=NakagawaTomio en-aut-sei=Nakagawa en-aut-mei=Tomio kn-aut-name=中川富夫 kn-aut-sei=中川 kn-aut-mei=富夫 aut-affil-num=2 ORCID= en-aut-name=YamamotoMichinori en-aut-sei=Yamamoto en-aut-mei=Michinori kn-aut-name=山本道法 kn-aut-sei=山本 kn-aut-mei=道法 aut-affil-num=3 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=4 ORCID= en-aut-name=SakaeKatsuyoshi en-aut-sei=Sakae en-aut-mei=Katsuyoshi kn-aut-name=栄勝美 kn-aut-sei=栄 kn-aut-mei=勝美 aut-affil-num=5 ORCID= en-aut-name=ShimizuMitsuharu en-aut-sei=Shimizu en-aut-mei=Mitsuharu kn-aut-name=清水光春 kn-aut-sei=清水 kn-aut-mei=光春 aut-affil-num=6 ORCID= en-aut-name=NiiyaHarutaka en-aut-sei=Niiya en-aut-mei=Harutaka kn-aut-name=新屋晴孝 kn-aut-sei=新屋 kn-aut-mei=晴孝 aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=8 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=10 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=川崎祥二 kn-aut-sei=川崎 kn-aut-mei=祥二 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 en-keyword=エピネフリン kn-keyword=エピネフリン en-keyword=放射線防護剤 kn-keyword=放射線防護剤 en-keyword=血管収縮 kn-keyword=血管収縮 en-keyword=酸素効果 kn-keyword=酸素効果 en-keyword=マウス粘膜皮膚 kn-keyword=マウス粘膜皮膚 END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=15 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical application of the contrast media containing soft drinks for the X-ray examination of the stomach kn-title=清涼飲料入り胃X線検査用造影剤の臨床応用 en-subtitle= kn-subtitle= en-abstract=Barium sulfate suspensions are disliked by many people. This is one of the obstacles to increase persons who consult doctors and to have medical examinations smoothly. We mixed soft drinks into the suspensions to improve this problem. As a result, they were popular among 64.2% people, there were not any clinical troubles that the suspensions did not stick to the mucous membrane of the stomach well, the peristalsis of the sotmach were promoted, and so on. These results suggest that the contrast media containing soft drinks is useful for the X-ray examinations of the stomach. kn-abstract=胃X線検査の被験者を増やし、検査を円滑に行う上で造影剤である硫酸バリウム懸濁液の飲みにくさが障害の一つとなっている。これを改善する目的で、懸濁液に市販の粉末清涼飲料を混入したところ、64.2％の人が通常のものよりも飲みやすいと答えた。臨床上も造影剤の付着が悪くなったり、胃の蠕動を促進する等の問題は生じず、有用であると考えられた。 en-copyright= kn-copyright= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=1 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=3 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=4 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=OkuraYasuhiko en-aut-sei=Okura en-aut-mei=Yasuhiko kn-aut-name=大倉保彦 kn-aut-sei=大倉 kn-aut-mei=保彦 aut-affil-num=7 ORCID= en-aut-name=NatsukawaKoichi en-aut-sei=Natsukawa en-aut-mei=Koichi kn-aut-name=夏川浩一 kn-aut-sei=夏川 kn-aut-mei=浩一 aut-affil-num=8 ORCID= en-aut-name=TandaniNobuyoshi en-aut-sei=Tandani en-aut-mei=Nobuyoshi kn-aut-name=丹谷延義 kn-aut-sei=丹谷 kn-aut-mei=延義 aut-affil-num=9 ORCID= en-aut-name=NobuharaEitaro en-aut-sei=Nobuhara en-aut-mei=Eitaro kn-aut-name=延原栄太朗 kn-aut-sei=延原 kn-aut-mei=栄太朗 aut-affil-num=10 ORCID= en-aut-name=MoriokaYasuki en-aut-sei=Morioka en-aut-mei=Yasuki kn-aut-name=森岡泰樹 kn-aut-sei=森岡 kn-aut-mei=泰樹 aut-affil-num=11 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=12 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=(財)倉敷成人病センター南くらしき病院放射線部 affil-num=8 en-affil= kn-affil=(財)倉敷成人病センター南くらしき病院放射線部 affil-num=9 en-affil= kn-affil=(財)倉敷成人病センター南くらしき病院放射線部 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=11 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=12 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=13 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=造影剤 (contrast media) kn-keyword=造影剤 (contrast media) en-keyword=硫酸バリウム (barium sulfate suspension) kn-keyword=硫酸バリウム (barium sulfate suspension) en-keyword=清涼飲料 (soft drinks) kn-keyword=清涼飲料 (soft drinks) en-keyword=消化管検査 (barium examination) kn-keyword=消化管検査 (barium examination) END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=1 end-page=5 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Measurement of intracellular pH by flow cytometry using pH sensitive fluorescence dye, and influence of hyperthermia and amiloride derivatives on the intracellular pH kn-title=蛍光pH指示薬を用いたフローサイトメトリーによる細胞内pHの測定と温熱およびアミロライド誘導体の細胞内pHへの影響 en-subtitle= kn-subtitle= en-abstract=We examined relationship between intensity of intracellular fluorescence of [2', 7'-bis-(2'-carboxyethyl) carboxyfluorescein] (BCECF) and intracellular pH in Ehrlich ascites tumor cells and their adriamycin-resistant strain, and found a good correlation between them at both strains. This suggests that changes in the intracellular pH on these strains may be obtained through measurement of intracellular fluorescence of BCECF by flow cytometry. Further, we examined influence of hyperthermia, 3, 5-diamino-6-chloro-N-(diaminomethylene)pyrazinecarboxamide (amiloride), an inhibitor of Na(+)/H(+) exchanger, and its derivative; N-amidino-3-amino-6-chloro-5-(N-ethylisopropylamino) pyrazinecarboxyamide (MH-12-43) on the intracellular pH in Ehrlich ascites tumor cells. The treatment of 0.5mM amiloride or 0.05mM MH-12-43 reduced intracellular pH at 37℃, while the more reduction was observed by the treatment at 42℃. The reduction of intracellular pH by 0.05mM MH-12-43 was more substantial than that of 0.5mM amiloride at 42℃. kn-abstract=エールリッヒ腹水癌細胞とそのアドリアマイシン耐性細胞において蛍光pH指示薬2'、7'-bis-(2-carboxyethyl) carboxyfluorescein] (BCECF) の蛍光量をフローサイトメトリーで測定することによって細胞内pHの検量曲線を作成することができた。このことより、これらの細胞においてBCECFの蛍光量で細胞内pHの変化を簡易に比較できることを示唆した。さらに、温熱、Na(+)/H(+) exchanger の阻害例であるアミロライド[3,5-diamino-6-chloro-N-(diaminomethylene) pyrazinecarboxamide]、およびアミロライド誘導隊MH-12-43[N-amidino-3-amino-6-chloro-5-(N-ethyliso-propylamino) pyrazinecarboxyamide] の細胞内pHへの影響をエールリッヒ腹水癌細胞で観察した。37℃では、0.5mMアミロライド、0.05mM　MH-12-43により細胞内pHは減少し、42℃処理によりさらに減少した。42℃において、0.05mM　MH-12-43による細胞内pHの減少は、0.5mMアミロライドによる減少より大きかった。 en-copyright= kn-copyright= en-aut-name=AsaumiJun-ichi en-aut-sei=Asaumi en-aut-mei=Jun-ichi kn-aut-name=浅海淳一 kn-aut-sei=浅海 kn-aut-mei=淳一 aut-affil-num=1 ORCID= en-aut-name=KawasakiShoji en-aut-sei=Kawasaki en-aut-mei=Shoji kn-aut-name=川崎祥二 kn-aut-sei=川崎 kn-aut-mei=祥二 aut-affil-num=2 ORCID= en-aut-name=KurodaMasahiro en-aut-sei=Kuroda en-aut-mei=Masahiro kn-aut-name=黒田昌宏 kn-aut-sei=黒田 kn-aut-mei=昌宏 aut-affil-num=3 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=4 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=BCECF kn-keyword=BCECF en-keyword=細胞内pH (Intracellular pH) kn-keyword=細胞内pH (Intracellular pH) en-keyword=フローサイトメトリー (Flow Cytometry) kn-keyword=フローサイトメトリー (Flow Cytometry) en-keyword=アミロライド (Amiloride) kn-keyword=アミロライド (Amiloride) en-keyword=MH-12-43 kn-keyword=MH-12-43 END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=2 article-no= start-page=99 end-page=106 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=スクリーン／フィルム乳房撮影法における乳房線量測定システム kn-title=Breast dosimetry system in screen/film mammography en-subtitle= kn-subtitle= en-abstract=乳房X線撮影法において乳腺組織に対する平均放射線吸収線量，すなわち平均乳腺線量は放射線のリスクの最も有用な測定法であり，現在，乳房に対する線量の評価に用いられている指標である。一般に，平均乳腺線量は線質（HVL），X線管球ターゲット材料，管電圧，圧迫乳房厚さ，乳房構成および（ある程度）X線管電圧波形の関数であるとされている。平均乳腺線量は，上記の関数についての情報を備えた表が公表されており，一般にその表を使って決定されている。近年，インバータ式といわれる高周波X線発生装置が普及してきた。しかし，その装置用の表は，まだ公表されていない。我々の研究では，乳房組織をシュミレートするファントム（0〜100％乳腺組織，0〜100％脂肪組織）を使用して，28kVでMoターゲット―Moフィルタソースアセンブリーを備えた高周波X線発生装置のために，平均乳腺線量用のルックアップテーブルを作成した。同様に，乳房組織をシュミレートするファントムを使用して，乳房X線写真から，ディジタル・イメージプロセシング技術によって，乳房構成の評価を試みた。そして，ディジタイズされた臨床乳房X線写真から，平均乳腺線量を自動的に計算するシステムを構築した。サンプル数が少ないため断定はできないが，日本女性は，基準構成（50％の脂肪および50％の乳腺組織）と比較すると，脂肪が少ない傾向を分析結果は示唆していた。また，平均乳腺吸収線量の限度は，明確に規定されていないが，American College of Radiology（ACR）は4 mGyなどを推奨している。また日本では，3 mGyが推奨されているが，我々の撮影システムはこれらを十分満足していた。このように本システムは，平均乳腺線量の客観的な評価に寄与するとともに，DR（digital radiography）などに応用すると，すなわちルックアップテーブルをDRのコンピュータに保存しておけば，撮影後すぐに乳房構成および平均乳腺線量を算出できる可能性をもつ。 kn-abstract=The average glandular dose to glandular tissue m mammography is generally assumed to be a function of beam quality (HVL), x-ray tube target material, tube voltage, breast thickness, breast composition and, to a lesser extent, x-ray tube voltage waveform. The average glandular dose is generally determined from published tables with knowledge of the above function. Tables for a high frequency x-ray generator are not yet published. In our study, the lookup tables for the average glandular dose were made at 28 kV (high frequency x-ray generator), employing a breast simulating tissue (0-100% adipose tissue, 0-100% glandular tissue) phantom for an Mo target - Mo filter source assembly. We tried to estimate breast composition from x-ray mammograms by digital image processing techniques, also using the simulating tissue phantom. Then the system that automatically calculates the average glandular dose from digitized clinical x-ray mammograms was built. It is considered that this system can contribute to objective evaluation of the average glandular dose. en-copyright= kn-copyright= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=1 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=2 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=3 ORCID= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=4 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=KadohisaShigefumi en-aut-sei=Kadohisa en-aut-mei=Shigefumi kn-aut-name=門久繁文 kn-aut-sei=門久 kn-aut-mei=繁文 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=5 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=6 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=Screen/Film Mammography (スクリーン／フィルム乳房撮影法) kn-keyword=Screen/Film Mammography (スクリーン／フィルム乳房撮影法) en-keyword=Breast composition (乳房構成) kn-keyword=Breast composition (乳房構成) en-keyword=Average glandular dose (平均乳腺線量) kn-keyword=Average glandular dose (平均乳腺線量) en-keyword=Entrance skin exposure (皮膚入射線量) kn-keyword=Entrance skin exposure (皮膚入射線量) en-keyword=Breast-equivalent material phantom (乳房組織等価ファントム) kn-keyword=Breast-equivalent material phantom (乳房組織等価ファントム) END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=2 article-no= start-page=59 end-page=64 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A study of x-rays protection in a hip-joint radiography examination kn-title=股関節X線撮影時の女性生殖腺防護についての検討 en-subtitle= kn-subtitle= en-abstract=Usually in a hip-joint radiographic examination for the youth including children, the gonads should be well protected with an appropriate lead shield etc. Since the male gonads are in the outside of the body, if covered with a lead shield, the shield can protect them. However, in the case of the female, since the gonads of exist in a pelvic cavity, the lead shield is cut to a specific pattern so that it can protect the ovaries and the womb, and it is set on the abdomen during the radiographic exposure. Since the scattered radiation on an X-ray film can be removed with the grid, the image of a lead shield is obtained clearly, and the gonads seem to be protected completely. The shield can not protect the gonads of the female from the scattered radiation, though it protects them almost completely from the primary X-rays beam. Therefore, the gonads have radioactive contamination from scattered radiation. Then, in order to estimate the amount of scattered radiation under the lead shield, the dose under the shield was measured by using a phantom in this research, changing lead shield width, the tube-voltage, and the monitoring depth of a phantom. As a results, the dose under the lead shield was observed considerably and showed the peak at the depth of 3 or 4cm. Therefore, it was thought that a careful caution was required for obviating lead shield in clinical. kn-abstract=幼小児を含めた若年者の股関節X線撮影検査においては鉛板などで生殖腺を防護して行うのが通常である。男性の場合は生殖腺は体外に露出しているので，それを鉛板で包むようにすればある程度目的は達成される。しかし，女性の場合，生殖腺は骨盤腔内に存在するため，卵巣及び子宮を防護でき診断目的領域にかからないように鉛板を成形し，腹壁上に置いて撮影する。X斬写真上ではグリッドで散乱線を除去しているため，鉛板の陰影がくっきりと撮影され，生殖腺は完全に防護されているように見える。しかし，体内では散乱線によるかなりの被曝があるものと考えられる。そこで今回，鉛板下の散乱線量を鉛板幅及び電圧を変化させ，ファントム内各深さの散乱線量を測定した。その結果，鉛板下の散乱線量が相当量認められ，その量は深さ3〜4cmでピークを形成した。鉛板幅による変化は幅が狭いほど線量は大きくなり，電圧による変化は60kVと80kVを比べると80kVの方が多くなった。これを鉛板なしの場合と比較すると，ファントム内意さが増すにしたがい増大した。したがって，臨床において鉛板がずれて再撮影をすることのないよう細心の注意が必要であると考えられた。 en-copyright= kn-copyright= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=1 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=2 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=3 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=4 ORCID= en-aut-name=ShibuyaKoichi en-aut-sei=Shibuya en-aut-mei=Koichi kn-aut-name=澁谷光一 kn-aut-sei=澁谷 kn-aut-mei=光一 aut-affil-num=5 ORCID= en-aut-name=TamuraEri en-aut-sei=Tamura en-aut-mei=Eri kn-aut-name=田村恵里 kn-aut-sei=田村 kn-aut-mei=恵里 aut-affil-num=6 ORCID= en-aut-name=TanimotoEriko en-aut-sei=Tanimoto en-aut-mei=Eriko kn-aut-name=谷本江利子 kn-aut-sei=谷本 kn-aut-mei=江利子 aut-affil-num=7 ORCID= en-aut-name=ToriiFumiko en-aut-sei=Torii en-aut-mei=Fumiko kn-aut-name=鳥居史子 kn-aut-sei=鳥居 kn-aut-mei=史子 aut-affil-num=8 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=9 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=5 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科　学生 affil-num=7 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科　学生 affil-num=8 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科　学生 affil-num=9 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=10 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 en-keyword=股関節X線撮影 (Radiography Examination of Hip-joint) kn-keyword=股関節X線撮影 (Radiography Examination of Hip-joint) en-keyword=医療被爆 (Patient Dose) kn-keyword=医療被爆 (Patient Dose) en-keyword=X線測定 (Dosimetry) kn-keyword=X線測定 (Dosimetry) en-keyword=生殖腺防護 (X-rays Protection of the Gonads) kn-keyword=生殖腺防護 (X-rays Protection of the Gonads) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19840331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=X線照射によるラット臓器中のメタロチオネインの変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END