| FullText URL | fulltext.pdf |
|---|---|
| Author | Yasuda, Yukiko| Sakai, Akiko| Ito, Sachio| Sasai, Kaori| Ishizaki, Akisada| Okano, Yoshiya| Kawahara, Seito| Jitsumori, Yoshimi| Yamamoto, Hiromasa| Matsubara, Nagahide| Shimizu, Kenji| Katayama, Hiroshi| |
| Keywords | NINEIN centrosome single nucleotide polymorphism colon cancer tumor susceptibility |
| Published Date | 2020-8-27 |
| Publication Title | Biomedical Reports |
| Volume | volume13 |
| Issue | issue5 |
| Publisher | Spandidos Publications |
| Start Page | 45 |
| ISSN | 2049-9434 |
| NCID | AA12610729 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 32934817 |
| DOI | 10.3892/br.2020.1352 |
| Web of Science KeyUT | 000606302400011 |
| Related Url | isVersionOf https://doi.org/10.3892/br.2020.1352 |
| Author | Yasuda, Yukiko| Sakai, Akiko| Ito, Sachio| Sasai, Kaori| Yamamoto, Hiromasa| Matsubara, Nagahide| Ouchida, Mamoru| Katayama, Hiroshi| Shimizu, Kenji| |
|---|---|
| Published Date | 2017-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume71 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54826 |
| FullText URL | Epilepsia_49_3_521.pdf |
|---|---|
| Author | Ohmori, Iori| Ouchida, Mamoru| Kobayashi, Katsuhiro| Jitsumori, Yoshimi| Inoue, Takushi| Shimizu, Kenji| Matsui, Hideki| Ohtsuka, Yoko| Maegaki, Yoshihiro| |
| Keywords | Rasmussen encephalitis SCN1A genetic-environmental interaction |
| Published Date | 2007-11-21 |
| Publication Title | Epilepsia |
| Volume | volume49 |
| Issue | issue3 |
| Publisher | Blackwell |
| Start Page | 521 |
| End Page | 526 |
| ISSN | 0013-9580 |
| NCID | AA00180597 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 18031552 |
| DOI | 10.1111/j.1528-1167.2007.01411.x |
| Web of Science KeyUT | 000253477800020 |
| Related Url | isVersionOf https://doi.org/10.1111/j.1528-1167.2007.01411.x |
| Author | Ito, Tatsuo| Ouchida, Mamoru| Morimoto, Yuki| Yoshida, Aki| Jitsumori, Yoshimi| Ozaki, Toshifumi| Sonobe, Hiroshi| Inoue, Hajime| Shimizu, Kenji| |
|---|---|
| Published Date | 2005-06-28 |
| Publication Title | Cancer Letters |
| Volume | volume224 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/47013 |
|---|---|
| FullText URL | 65_5_315.pdf |
| Author | Wang, Lei| Kaku, Haruki| Huang, Peng| Xu, Kexin| Yang, Kai| Zhang, Jiheng| Li, Ming| Xie, Liping| Wang, Xiaofeng| Sakai, Akiko| Watanabe, Masami| Nasu, Yasutomo| Shimizu, Kenji| Kumon, Hiromi| Na, Yanqun| |
| Abstract | Deficiencies in the human DNA repair gene WRN are the cause of Werner syndrome, a rare autosomal recessive disorder characterized by premature aging and a predisposition to cancer. This study evaluated the association of WRN Leu1074Phe (rs1801195), a common missense single nucleotide polymorphism in WRN, with prostate cancer susceptibility in Chinese subjects. One hundred and forty-seven prostate cancer patients and 111 male cancer-free control subjects from 3 university hospitals in China were included. Blood samples were obtained from each subject, and the single nucleotide polymorphism WRN Leu1074Phe was genotyped by using a Snapshot assay. The results showed that WRN Leu1074Phe was associated with the risk of prostate cancer in Chinese men and that the TG/GG genotype displayed a decreased prevalence of prostate cancer compared with the TT genotype (OR＝0.58, 95%CI:0.35-0.97, p＝0.039). Through stratified analysis, more significant associations were revealed for the TG/GG genotype in the subgroup with diagnosis age <_ 72 yr (OR＝0.27, 95%CI:0.12-0.61, p＝0.002) and in patients with localized diseases (OR＝0.36, 95%CI:0.19-0.70, p＝0.003). However, no statistically significant difference was found in the subgroup with age ＞72 yr or in patients with advanced diseases. We concluded that the genetic variant Leu1074Phe in the DNA repair gene WRN might play a role in the risk of prostate cancer in Chinese subjects. |
| Keywords | polymorphism prostatic neoplasms single nucleotide susceptibility WRN |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-10 |
| Volume | volume65 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 315 |
| End Page | 323 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22037267 |
| Web of Science KeyUT | 000296116400005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yano, Masaaki| Ouchida, Mamoru| Shigematsu, Hisayuki| Tanaka, Noriyoshi| Ichimura, Koichi| Kobayashi, Kazuyasu| Inaki, Yasuhiko| Toyooka, Shinichi| Tsukuda, Kazunori| Shimizu, Nobuyoshi| Shimizu, Kenji| |
| Keywords | alternative splicing HELLS loss of heterozygosity lung cancer SMARCA6 |
| Note | Digital Object Identifer:10.1002/ijc.20407 Published with permission from the copyright holder. This is the author's copy, as published in the Journal of International Journal of Cancer, October 2004, Volume 112, Issue 1, Pages 8-13. Publisher URL:http://dx.doi.org/10.1002/ijc.20407 Direct access to Thomson Web of Science record Copyright © 2004 Wiley-Liss, Inc. All rights reserved.| |
| Published Date | 2004-10-20 |
| Publication Title | International Journal of Cancer |
| Volume | volume112 |
| Issue | issue1 |
| Publisher | Wiley-Liss, Inc. |
| Start Page | 8 |
| End Page | 13 |
| ISSN | 0020-7136 |
| NCID | AA00680002 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Wiley-Liss, Inc. |
| File Version | author |
| PubMed ID | 15305370 |
| DOI | 10.1002/ijc.20407 |
| Web of Science KeyUT | 000223939100002 |
| Author | 清水 憲二| |
|---|---|
| Published Date | 2003-01-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume114 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Shimizu, Kenji| |
|---|---|
| Published Date | 1996-09 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume13 |
| Content Type | Others |
| Author | Ishii, Tatsuhiro| Murakami, Jun| Notohara, Kenji| Sasamoto, Hiromi| Kambara, Takeshi| Shirakawa, Yasuhiro| Naomoto, Yoshio| Ouchida, Mamoru| Shimizu, Kenji| Jeremy, R. Jass| Matsubara, Nagahide| Tanaka, Noriaki| |
|---|---|
| Published Date | 2007-09-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume119 |
| Issue | issue2 |
| Content Type | Journal Article |
