start-ver=1.4
cd-journal=joma
no-vol=66
cd-vols=
no-issue=2
article-no=
start-page=143
end-page=154
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201204
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Attenuated Sensory Deprivation-induced Changes of Parvalbumin Neuron Density in the Barrel Cortex of FcƒÁRllB-deficient Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Recent studies have demonstrated the important role of immune molecules in the development of neuronal
circuitry and synaptic plasticity. We have detected the presence of FcƒÁRllB protein in parvalbumin-
containing inhibitory interneurons (PV neurons). In the present study, we examined the appearance
of PV neurons in the barrel cortex and the effect of sensory deprivation in FcƒÁRllB-deficient mice (FcƒÁRllB-/-) and wild-type mice. There was no substantial difference in the appearance of PV neurons
in the developing barrel cortex between FcƒÁRllB-/- and wild-type mice. Sensory deprivation from immediately after birth (P0) or P7 to P12-P14 induced an increase in PV neurons. In contrast, sensory deprivation from P7 or P14 to P28, but not from P21 to P28, decreased PV neurons in wild-type mice. However, sensory deprivation from P0 or P7 to P12-P14 did not increase PV neurons and sensory deprivation from P7 or P14 to P28 did not decrease or only modestly decreased PV neurons in FcƒÁRllB-/- mice. The results indicate that expression of PV is regulated by sensory experience and the second and third postnatal weeks are a sensitive period for sensory deprivation, and suggest that FcƒÁRllB contributes to sensory experience-regulated expression of PV.
en-copyright=
kn-copyright=

en-aut-name=WatanabeMakiko
en-aut-sei=Watanabe
en-aut-mei=Makiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=UenoHiroshi
en-aut-sei=Ueno
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SuemitsuShunsuke
en-aut-sei=Suemitsu
en-aut-mei=Shunsuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=YokobayashiEriko
en-aut-sei=Yokobayashi
en-aut-mei=Eriko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=MatsumotoYosuke
en-aut-sei=Matsumoto
en-aut-mei=Yosuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=UsuiShinichi
en-aut-sei=Usui
en-aut-mei=Shinichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

en-aut-name=SujiuraHiroko
en-aut-sei=Sujiura
en-aut-mei=Hiroko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=3
en-affil=
kn-affil=Koyodai Hospital

affil-num=4
en-affil=
kn-affil=Department of Psychiatry, Kawasaki Medical University

affil-num=5
en-affil=
kn-affil=Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

affil-num=6
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=7
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=8
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University
en-keyword=parvalbumin
kn-keyword=parvalbumin
en-keyword=fast-spiking interneurons
kn-keyword=fast-spiking interneurons
en-keyword=FcƒÁRllB
kn-keyword=FcƒÁRllB
en-keyword=barrel cortex
kn-keyword=barrel cortex
en-keyword=sensory deprivation
kn-keyword=sensory deprivation
END

start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=3
article-no=
start-page=135
end-page=143
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=201306
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Somatosensory and Visual Deprivation Each Decrease the Density of Parvalbumin Neurons and Their Synapse Terminals in the Prefrontal Cortex and Hippocampus of Mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In the phenomenon known as cross-modal plasticity, the loss of one sensory system is followed by improved functioning of other intact sensory systems. MRI and functional MRI studies suggested a role of the prefrontal cortex and the temporal lobe in cross-modal plasticity. We used a mouse model to examine the effects of sensory deprivation achieved by whisker trimming and visual deprivation achieved by dark rearing in neonatal mice on the appearance of parvalbumin (PV) neurons and the formation of glutamic acid decarboxylase 67 (GAD67)-positive puncta around pyramidal neurons in the prefrontal cortex and hippocampus. Whisker trimming, but not dark rearing, decreased the density of PV neurons in the hippocampus at postnatal day 28 (P28). In the prefrontal cortex, whisker trimming and dark rearing decreased the density of PV neurons in layer 5/6 (L5/6) at P28 and in L2/3 at P56, respectively, whereas dark rearing increased the density of PV neurons in L5/6 at P56. Whisker trimming decreased the density of GAD67-positive puncta in CA1 of the hippocampus at both P28 and P56 and in L5/6 of the prefrontal cortex at P28. Dark rearing decreased the density of GAD67-positive puncta in CA1 of the hippocampus and in both L2/3 and L5/6 of the prefrontal cortex at P28, and in L2/3 of the prefrontal cortex at P56. These results demonstrate that somatosensory or visual deprivation causes changes in the PV-interneuronal network in the mouse prefrontal cortex and hippocampus. The results also suggest that the alteration of the PV-interneuronal network, especially in the prefrontal cortex, may contribute to cross-modal plasticity.
en-copyright=
kn-copyright=

en-aut-name=UenoHiroshi
en-aut-sei=Ueno
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=

en-aut-name=ShoshiChikafumi
en-aut-sei=Shoshi
en-aut-mei=Chikafumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=

en-aut-name=SuemitsuShunsuke
en-aut-sei=Suemitsu
en-aut-mei=Shunsuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=

en-aut-name=UsuiShinichi
en-aut-sei=Usui
en-aut-mei=Shinichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=

en-aut-name=SujiuraHiroko
en-aut-sei=Sujiura
en-aut-mei=Hiroko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=

en-aut-name=OkamotoMotoi
en-aut-sei=Okamoto
en-aut-mei=Motoi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=

affil-num=1
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=2
en-affil=
kn-affil=Department of Medical Technology, Kawasaki College of Allied Health Professions

affil-num=3
en-affil=
kn-affil=Department of Psychiatry, Kawasaki Medical University

affil-num=4
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=5
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University

affil-num=6
en-affil=
kn-affil=Department of Medical Technology, Graduate School of Health Sciences, Okayama University
en-keyword=sensory deprivation
kn-keyword=sensory deprivation
en-keyword=parvalbumin
kn-keyword=parvalbumin
en-keyword=glutamate decarboxylase (GAD67)
kn-keyword=glutamate decarboxylase (GAD67)
en-keyword=prefrontal cortex
kn-keyword=prefrontal cortex
en-keyword=hippocampus
kn-keyword=hippocampus
END