start-ver=1.4 cd-journal=joma no-vol=54 cd-vols= no-issue=1 article-no= start-page=1 end-page=8 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=1979 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=殺菌剤、ベノミル、チウラムの土壌微生物相と2～3の土壌生息性糸状菌に及ぼす影響 kn-title=Effect of Fungicides, Benomyl and Thiram on Soil Microflora and Some Inhabitant Fungi en-subtitle= kn-subtitle= en-abstract= kn-abstract=Effects of Benomyl and Thiram on the soil microflora and some soil inhabitant fungi were studied using the_ soil (sandy loam) of the experimental field, Okayama University. Under field conditions, heavy application of Benomyl did not affect significantly the soil microflora. Thiram, however, reduced the fungal population in soil to 1/6 at the next day of treatment, but recovered to the normal level after 6 days. Under laboratory conditions, both fungicides did not affect soil microflora. Population of Benomyl-to lerant fungi was about 1/10 of the total fungi and increased slightly in the field soil by treatment with Benomyl at the later stage of experiment during June to October. Neither Thiram-tolerant fungus nor bacterium was found in both Thiram-treated and non-treated soils. A fungus highly tolerant to Benomyl was isolated and identified as Aspergillus versicolor, and found to not have the metabolic activity to degrade BCM. The absorption of BCM by the mycelia of this tolerant fungus, A. versicolor, was less than half of the BCM-sensitive one, such as Cladosporium harbarum. en-copyright= kn-copyright= en-aut-name=OkuHachiro en-aut-sei=Oku en-aut-mei=Hachiro kn-aut-name=奥八郎 kn-aut-sei=奥 kn-aut-mei=八郎 aut-affil-num=1 ORCID= en-aut-name=OkiKazuo en-aut-sei=Oki en-aut-mei=Kazuo kn-aut-name=沖和生 kn-aut-sei=沖 kn-aut-mei=和生 aut-affil-num=2 ORCID= en-aut-name=ShiraishiTomonori en-aut-sei=Shiraishi en-aut-mei=Tomonori kn-aut-name=白石友紀 kn-aut-sei=白石 kn-aut-mei=友紀 aut-affil-num=3 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤健二 kn-aut-sei=佐藤 kn-aut-mei=健二 aut-affil-num=4 ORCID= en-aut-name=OuchiSeiji en-aut-sei=Ouchi en-aut-mei=Seiji kn-aut-name=大内成志 kn-aut-sei=大内 kn-aut-mei=成志 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=Okayama Agricultural Experiment Station affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=60 cd-vols= no-issue=580 article-no= start-page=258 end-page=265 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19941225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental Study on Latent Cold Heat Storage by means of Oil Droplets with Low Freezing Point : 1st Report, Flow and Solidification Characteristics of Tetradecane Droplets Ascending in Low-Temperature Water Solution kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷に関する基礎研究 : 第1報,低温水溶液中を浮上するテトラデカン油滴の流動および凝固特性 en-subtitle= kn-subtitle= en-abstract=近年、大都市圏における夏期昼夜間電力利用格差是正対策の一つとして、安価な深夜電力を利用する潜熱蓄冷システムに関する研究・開発が行われるようになり、氷蓄冷システムを始めとして既に実用化されているものもある。特に潜熱蓄冷システムの蓄冷器、すなわち蓄冷物質と熱媒体とが隔離されている隔離方式と、互いに不溶性の蓄冷物質と熱媒体を直接接触させる直接接触方式とに分類される。前者の場合、潜熱蓄冷物質を金属あるいは樹脂製容器内に充填し、これらを熱媒体中に設置することにより熱交換を行ういわゆるカプセル型潜熱蓄冷システムがその代表例である。この場合蓄冷物質と熱媒体がカプセル壁により隔離されているため、熱媒体の清浄度を高く保てるという利点がある反面、カプセル自体が熱抵抗となり伝熱効率が低下し、熱交換器が大型化する等の欠点を有する。一方、後者は、熱媒体が蓄冷物質と直接接触するため、両者が相互に溶解しない場合はきわめて高い熱伝達効率を得ることができ、また装置が簡単かつ小型化できる等の利点を有している。本研究では、高性能潜熱蓄冷システムの開発を目的とし、低温冷媒水溶液中に疎水性液相蓄冷物質を噴射注入して微粒化させ、蓄冷物質が 密度差により低温水溶液中を浮上しながら低温水溶液との直接接触熱交換により凝固相変化を行い、蓄冷を完了するというシステムを提案するものである。本研究で対象とする潜熱蓄冷システムにおける熱交換は、分散相液体が凝固相変化を行う液－液、固－液共存型直接接触熱交換となるが、この種の直接接触熱交換に関する研究は、現状では見あたらないようである。従って、本研究は潜熱蓄冷システムの性能向上および分散相液体が凝固相変化挙動を伴う直接接触熱交換に関する諸因子の効果を、まず凝固現象の把握に焦点をあて、実験的に検討するものである。本実験では、蓄冷物質として融点、潜熱量および密度がそれぞれ5.8℃、229.1kj/kgおよび770kg/m3（6℃）のパラフィン系油であるテトラデカン油（C14H30）を選定し、低温水溶液にはこれと不溶性のエチレングリコール30wt％水溶液（以下水溶液）を用いることにより、水溶液中を浮上するテトラデカン油滴の凝固特性を可視実験により定性的に明らかにする。さらに、テトラデカン油噴射温度、速度、および低温水溶液温度を実験因子とした場合の油滴凝固率および蓄冷熱量の測定結果より定量的にこの種の蓄冷システムの可能性を検討するものである。 kn-abstract=Flow and solidification characteristics of tetradecane droplets [melting point of 5.8℃, latent heat of 229.1 kJ/kg, density of 770 kg/m^3 (at 6℃) ] ascending in ethlene glycol water solution of 30 weight percent at low temperature were investigated experimentally in order to examine the possibility of a liquid-liquid or liquid-solid direct-contact-type latent cold heat storage system. A new type of solidification rate meter is proposed in the present study. As a result, some interesting freezing behaviors of droplets were observed by the visualization technique. From the measurements of solidification rate of tetradecane droplets, the relationships between the solidification rate and some experimental parameters were clarified. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤憲二 kn-aut-sei=佐藤 kn-aut-mei=憲二 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 en-keyword=Latent Cold Heat Storage kn-keyword=Latent Cold Heat Storage en-keyword=Direct Contact Freezing kn-keyword=Direct Contact Freezing en-keyword=Tetradecane Droplet kn-keyword=Tetradecane Droplet en-keyword=Buoyancy kn-keyword=Buoyancy en-keyword=Solidification Rate kn-keyword=Solidification Rate END start-ver=1.4 cd-journal=joma no-vol=62 cd-vols= no-issue=593 article-no= start-page=325 end-page=332 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960125 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental Study on Latent Cold Heat Storage by means of Oil Droplets with Low Freezing Point : 2nd Report, Nondimensional Analysis of Solidification and Heat Transfer Characteristics of Tetradecane Oil Droplets Ascending in Low-Temperature Water Solution kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷に関する基礎研究 : 第2報, 低温水溶液中を浮上するテトラデカン油滴の凝固および熱伝達の無次元整理式 en-subtitle= kn-subtitle= en-abstract=前報において、直接接触による潜熱蓄冷システムを提案し、その構築のための基礎的データを報告した。すなわち、テトラデカン油（C14H10、融点Tm=5.8℃、融解潜熱L=229.1kj/kg、密度Ρdl=770kg/m3(液相時、6℃)）およびエチレングリコール水溶液をそれぞれ蓄冷材および低温冷媒液として用い、両者を直接接触させることによる。蓄冷材の凝固挙動について明らかにした。通常、テトラデカン油の噴射温度および水溶液温度を低下させるに伴い、増加する傾向にある。しかし、温度条件を極度に低下させると、ノズル先端にてテトラデカン油の凍結が起こり、いわゆる凝固油柱が発生し、逆に温度の低下と共に、凝固率が減少するという特徴的な現象を見い出した。また、本蓄冷システムにおいては、蓄冷部にて蓄冷材としての油滴が液相から固相へと凝固相変化するため、液－液および固－液系の直接接触熱交換が共存することになり、それぞれ異なった伝熱形態となる。本報告では、テトラデカン油滴群の凝固率および熱伝達率を主に実験データを基礎に整理する方法を検討するものである。前述したように、実験条件によりノズル先端に凝固油柱が形成される場合とされない場合があり、それぞれの場合における実験整理式の提案と本蓄冷システムの最適な運転条件についての考察を行っている。 kn-abstract=The latent cold heat storage system using the direct-contact freezer with tetradecane oil and ethylene glycol aqueous solution as the latent cold heat storage material and the cold heat transfer medium, respectively, was proposed in a previous paper [Inaba and Sato, Trans. JSME, 60-580 (1994), 4236.]. In this report, in order to obtain practical data for industrial application, nondimensional analysis of the solidification rate of the tetradecane oil droplets and the overall heat transfer coefficient in the freezer was carried out. In this system, the tetradecane oil droplets change from liquid to solid state during ascension in the cold heat transfer medium. Therefore, liquid-liquid and solid-liquid coexisting-type direct-contact heat transfer occurs between the tetradecane oil droplets and the aqueous solution. It can be considered that the flow pattern and heat transfer process are different for the liquid-liquid and the solid-liquid systems. The empirical equations of the solidification rate and the overall heat transfer coefficient were derived for the averaged values for the entire freezer. The optimum operating conditions at which the maximum solidification rate can be achieved were clarified. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤憲二 kn-aut-sei=佐藤 kn-aut-mei=憲二 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 en-keyword=Latent Cold Heat Storage kn-keyword=Latent Cold Heat Storage en-keyword=Direct Contact Freezing kn-keyword=Direct Contact Freezing en-keyword=Tetradecane Oil Droplet kn-keyword=Tetradecane Oil Droplet en-keyword=Solidification Rate kn-keyword=Solidification Rate en-keyword=Overall Heat Transfer Coefficient kn-keyword=Overall Heat Transfer Coefficient END start-ver=1.4 cd-journal=joma no-vol=62 cd-vols= no-issue=602 article-no= start-page=172 end-page=179 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19961025 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental Study on Latent Cold Heat Storage by means of Oil Droplets with Low Freezing Point : 3rd Report, Cold Heat Energy Release Characteristics of Direct-Contact Heat Exchange between Solidified Oil Droplets and Hot Air kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷熱に関する基礎研究 : 第3報, 粒状凝固潜熱蓄冷熱材と温空気の直接接触熱交換による放冷熱特性 en-subtitle= kn-subtitle= en-abstract=前報において、低温熱媒体槽中に非水溶液性油を噴射・凝固させることにより潜熱蓄冷熱を行う方法の提案を行った。このような潜熱蓄冷熱システムの放冷熱法として凝固した潜熱蓄冷熱材と暖かい空気を直接接触させて放冷熱を行う方法が考えられる。潜熱蓄冷熱材と熱媒体温空気が直接接触熱交換を行う場合、両者間の熱伝達効率が非常に高くなり、装置の高効率化および小型化が実現可能である。さらに、このような潜熱放冷熱法では、熱交換後の空気温度を蓄冷熱剤の融点に近づけることが可能であり、結果として必要とする空気温度に近い融点を持った潜熱蓄冷熱材を選ぶことにより、目的の熱交換後の空気温度を安定した状態で得られるという利点がある。しかしながら、この種の直接接触型潜熱放冷熱に関する研究は非常に少ない現状にある。本報告は、前報において述べた潜熱蓄冷熱材製造装置により得られた凝固油滴と水の混合物中に、下部から暖かい空気を吹き込み、微細な空気泡と凝固油滴の融解挙動および流通空気の熱交換特性について実験的に検討するものである。実験は無限に広い均一な凝固油滴層を対象とすることから、層最下部に多数の円形ノズルを均一に配列した分板を設置し、そこから温空気を層内に噴射した。このような直接接触熱交換法では、噴射空気泡により蓄冷熱充填層が流動するため、層内の温度場が均一となり、全ての凝固油滴において均一に融解が進行するという利点がある。さらに、凝固油滴と水の混合割合を変化させると凝固油滴層の流動状態をさまざまに変化させることが可能である。本報告は、実験因子としての入口空気温度、湿度および空気流量、そして凝固油滴混合水層高さが熱交換後の空気温度、湿度および潜熱放冷熱完了時間に及ぼす影響について実験的に検討し、これらの相関関係を実験式の形でまとめるものである。 kn-abstract=This paper deals with the cold latent heat energy release characteristics of direct-contact heat exchange between the solidified oil droplets [tetradecane, CH_3(CH_2)_<12>CH_3, melting point5.8℃] and hot air. Hot air is injected into the solidified oil droplet-water mixture layer from the distributor with a number of small circular nozzles. The solidified oil droplet-water mixture layer is fluidized by the air bubbles ascending in the layer, and the air bubbles are cooled from the layer by the direct-contact heat exchange. This paper deals with the characteristics of temperature and humidity of the outlet air from the layer, and time history of the cold heat energy release. The experiments were performed with respect to several experimental parameters, i. e., air flow rate, air temperature and humidity, and the amount of oil droplets and water in the mixture layer. Finally, some empirical correlations for the outlet air temperature and humidity and the finishing time of cold latent heat release were derived in terms of various nondimensional parameters. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤憲二 kn-aut-sei=佐藤 kn-aut-mei=憲二 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 en-keyword=Latent Cold Heat Release kn-keyword=Latent Cold Heat Release en-keyword=Direct-Contact Heat Exchange kn-keyword=Direct-Contact Heat Exchange en-keyword=Frozen Tetradecane Oil Droplet-Water Mixture kn-keyword=Frozen Tetradecane Oil Droplet-Water Mixture en-keyword=Temperature Efficiency kn-keyword=Temperature Efficiency en-keyword=Humidity kn-keyword=Humidity END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=607 article-no= start-page=267 end-page=274 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental Study on Latent Cold Heat Storage by Means of Oil Droplets at Low Freezing Point : 4th Report, Numerical Calculation of Motion and Solidification Characteristics of Oil Droplet Ascending in a Cold Water Solution by Buoyancy kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷熱に関する基礎研究 : 第4報, 低温水溶液中を浮上するテトラデカン油滴の流動および凝固特性に関する数値計算 en-subtitle= kn-subtitle= en-abstract=前報において、潜熱蓄冷熱材としての油滴と冷媒水溶液を直接接触熱交換させて蓄冷熱を行う、新しい潜熱蓄冷熱法について述べた。そして、潜熱蓄冷熱材油滴の凝固率の測定を行い、その結果、油滴の凝固率と、それを決定する因子である油滴の直径、油のノズル噴射流速および噴射温度、また冷媒水溶液温度との関係を実験的に明らかにした。しかしながら、前報ではこれらのパラメーターを実験装置の制限上、限られた範囲内で変化させており、同パラメーターを広範囲に変化させた場合の凝固率等についての検討は十分になされていない。また、油滴の凝固率に影響を与えるパラメーターをとして、前述の因子以外に冷媒水溶液流速が考えられる。従って、前報の実験範囲を超えたあるいは実験では困難な条件下における油滴の運動および凝固挙動に関する知見を得るためには、適当な物理モデルを設定し、数値計算により予想することが有効である。前報においても、油滴の凝固率の予測に関する簡単な計算を行っている。その結果、油滴のノズル噴射温度および水溶液温度の低下に伴い、油滴の凝固率は増加し、また、油滴の浮上速度が増大するに伴って、油滴の凝固率が減少するという結果を得た。しかしながら、同報告中における計算は、油滴の浮上速度は浮上過程において一定とし、また、油滴内部の温度は一様とした場合の諸因子と凝固率の関係を求めたものである。一方、実際に油滴が水溶液中を浮上する際には、ノズル出口から油滴が噴射された後、水溶液の流体抵抗により油滴は減速する。また、浮上過程にある油滴の内部には温度分布が生じているはずである。よって、これらを考慮した計算を行うことにより、より詳細な油滴の凝固挙動に関する評価が可能となる。本報告は、前報において述べた、低温冷媒水溶液中を浮上するテトラデカン油滴の凝固率を求めるための計算方法の提案と結果の検討を行うものである。本計算方法においては、まず、油滴を冷却そして凝固相に変化させた場合の凝固率を求めるための数値計算モデルの検討を行う。続いて、水溶液中における油滴の運動挙動に関する数値計算法の提案を行う。最終的に、油滴の凝固率および運動に関する計算結果を組み合わせて、実際に前報において述べた実験に相当する物理モデルに関しての数値計算を行うものである。対象とするパラメーターは、潜熱蓄冷熱材としての油滴の直径、油のノズル噴射流速および噴射温度、冷媒水溶液の温度および流速である。尚、テトラデカンおよび冷媒水溶液であるエチレングリコール30mass%水溶液の物性値は、前報に示す通りである。 kn-abstract=This paper proposes a numerical calculation method to predict solidification characteristics of paraffin oil droplets (tetradecane, CH_3(CH_2)_12CH_3,melting point is 5.8℃, diameter is 4～6mm) ascending in a cold water solution (mixture of ethylene glycol [CH_2OH・CH_2OH] and water, temperature is -2～-10℃) by buoyancy. The oil droplets start to ascend with several initial velocities and initial temperatures (10～60℃) in the water solution. The oil droplets are decelerated by hydraulic resistance of the water solution. The water solution flows vertically downward at a low velocity of 0.1 m/s. The temperature of the oil droplet decreases due to direct-contact heat transfer with the cold water solution, and the oil droplet starts to solidify when its surface temperature reaches the freezing point. The solidification rate of the oil droplet is calculated based on a combination of flow behavior and solidification characteristics of the oil droplet. As a result, the motion of the oil droplet, the completion height and time for solidification are determined. The parameters used are the diameter, initial velocity and initial temperature of the oil droplet, and temperature and velocity of water solution. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤憲二 kn-aut-sei=佐藤 kn-aut-mei=憲二 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 en-keyword=Energy Storage kn-keyword=Energy Storage en-keyword=Solidification kn-keyword=Solidification en-keyword=Numerical Analysis kn-keyword=Numerical Analysis en-keyword=Oil Droplet kn-keyword=Oil Droplet en-keyword=Direct-Contact Heat Exchange kn-keyword=Direct-Contact Heat Exchange en-keyword=Buoyancy kn-keyword=Buoyancy en-keyword=Ascending Velocity kn-keyword=Ascending Velocity END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=607 article-no= start-page=275 end-page=282 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Fundamental Study on Latent Cold Heat Storage by Means of Oil Droplets at Low Freezing Point : 5th Report, Flow and Solidification Characteristics of Oil Droplets Ascending in Low-Temperature Water Solution Having Various Flow Velocities kn-title=低凝固点油滴の凝固を利用した潜熱蓄冷熱に関する基礎研究 : 第5報, 低温水溶液流速を変化させた場合の浮上油滴の流動および凝固特性 en-subtitle= kn-subtitle= en-abstract=著者らは、前報において、潜熱蓄冷熱材としての非水溶性油滴と冷熱媒体としての低温水溶液を直接接触熱交換させて蓄冷熱を行う新しい潜熱蓄冷熱法を提案し、潜熱蓄冷熱材油滴の凝固率の測定を行った。その結果、油滴の凝固率とそれを決定する因子である油滴の直径、油のノズル噴射流速および噴射温度、また冷媒水溶液温度との関係を実験的に明らかにした。しかしながら、前報においては、試験部内を流動する冷熱媒体としての水溶液の流速は、静止状態に近い一定の低速条件にて凝固特性に関する検討を行った。従って、水溶液の流速が油滴の凝固特性に及ぼす効果の十分な検討はなされていない。本研究では、直接接触熱交換部としての試験部内において、低温水溶液は鉛直下方へと流動し、同上方へと浮上する油滴群と対向流動し、直接接触熱交換を行う。従って、下向きの水溶液流速の増大は、油滴の浮上速度の低下となり、結果的に、一定高さの水溶液中に油滴が滞留する時間の増大となる。この油滴の滞留時間の増加は、油滴の凝固率の増加となることが予想される。本報告は、前報において述べた低温水溶液層内での油滴の凝固特性に関連し、下向きの水溶液流速を増大させた場合の油滴の流動および凝固特性の実験的検討を行い、さらに水溶液流速を考慮した油滴の凝固率の無次元整理方法を提案するものである。流動する低温水溶液層中を浮上する油滴の凝固率を支配する因子として、温度条件以外に油滴の大きさ、油滴と水溶液間の熱伝達率、および油滴と水溶液間の熱交換時間が挙げられる。油滴と水溶液間の熱伝達率は、両者間の相対速度により支配されるが、前報においては、水溶液流速は一定かつ非常に低速であるため、油滴の絶対浮上速度により、油滴と水溶液間の熱伝達率を表し得た。さらに、油滴の絶対浮上速度は、油滴径により支配され、そして、油滴と水溶液間の熱交換時間、すなわち一定高さの水溶液中における油滴の絶対浮上速度により決定される。従って、前報においては、これらの三つの因子をまとめて表わす無次元パラメーターとして、油滴が凝固を開始する点における油滴の絶対浮上速度を代表浮上速度としたレイノルズ数の定義を行った。しかしながら、下向きの水溶液流速を増加させた場合、対向する油滴の絶対浮上速度は大きく低下し、試験部内における油滴の滞留時間、すなわち凝固進行のための熱交換時間が増加する。よって、この場合、油滴と水溶液間の熱伝達率を支配するレイノルズ数には、油滴と水溶液の間の相対速度を用いる必要があり、さらに水溶液中における油滴の滞留時間を表す無次元パラメーターが必要となる。本報告においては、以上のような観点に基づき、油滴の凝固率データの整理法を提案している。さらに、下向きに流動する低温水溶液と対向する浮上油滴の凝固を伴う流動挙動は、非常に複雑となることが予想されるため、油滴の流動および凝固様式について基本的な検討をおこなってある。 kn-abstract=Flow and solidification characteristics of tetradecane droplets [melting point of 5.8℃, latent heat of 229.1 kJ/kg, density of 770 kg/m^3 (at 6℃)] ascending in ethylene glycol water solution of 30 mass percent at low temperature were investigated experimentally in order to examine the existence of a liquid-liquid or liquid-solid direct-contact-type latent cold heat storage system. Some interesting freezing behaviors of droplets were observed under the conditions of various water solution flow velocities and oil-injection nozzle diameters by the visualization technique. Eventually, the relation-ships between the solidification rate and some experimental parameters were clarified. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤憲二 kn-aut-sei=佐藤 kn-aut-mei=憲二 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 en-keyword=Latent Cold Heat Storage kn-keyword=Latent Cold Heat Storage en-keyword=Direct Contact Freezing kn-keyword=Direct Contact Freezing en-keyword=Tetradecane Droplet kn-keyword=Tetradecane Droplet en-keyword=Buoyancy kn-keyword=Buoyancy en-keyword=Solidification Rate kn-keyword=Solidification Rate END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=非脱分極性筋弛緩薬が心臓手術中に得られたヒト心房組織中のノルエピネフリン放出に及ぼす影響 kn-title=Effects of non-depolarizing neuromuscular blocking agents on norepinephrine release from human atrial tissue obtained during cardiac surgery en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佐藤健治 kn-aut-sei=佐藤 kn-aut-mei=健治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=666 article-no= start-page=191 end-page=198 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Heat Transfer Enhancement of Water Flow in a Straight Pipe with Drag Reduction Surfactant by Using Wire Coil kn-title=ワイヤーコイルを用いた流動抵抗低減用界面活性剤添加水の直円管内熱伝達促進 en-subtitle= kn-subtitle= en-abstract=熱媒体水に鎖状高分子や界面活性剤等を微量添加することによる流動抵抗低減効果（トムズ効果）を利用した熱エネルギー輸送技術が注目されており、実用化に向けて様々な研究が行われている。著者らは、流動抵抗低減剤としての界面活性剤（第4級アンモニウム塩）を添加した水を、直円管内に流動させた場合の流動抵抗や熱伝達の測定、そして数値シミュレーションによる管内流動抵抗の予測検討結果を報告してきた。さらに、著者らは、実際の配管系を想定して、界面活性剤添加水による曲管内の流動抵抗と熱伝達特性の解明を行ってきた。一方において、使用済み界面活性剤の廃棄処理の問題、そして流動抵抗低減剤使用に伴う管内熱伝達の減少による熱交換効率の低下等、この種の流動抵抗低減法の欠点も指摘されている。後者の欠点を克服するために、熱交換器入口部にミセルスクィーザーを設けて界面活性剤の棒状ミセルを一時的に分断し、流動抵抗低減効果を消失させる方法や熱交換器の伝熱面にラムダ翼列状の乱流促進体の設置や伝熱面を祖面にすることによって、伝熱促進を検討した研究も行われ始めている。本研究は、」流動抵抗低減用界面活性剤利用による円管式熱交換器内の熱伝達低下を解消させるために、乱流促進体としてワイヤーコイルを円管内に挿入した場合の熱伝達促進効果と流動抵抗の関係を実験的に明らかにしようとするものである。このワイヤーコイルによる乱流促進法は、大幅に設備の改修を行うことなく既設の熱交換器への適応が可能であるなど、従来の方法よりも早急な実用化が期待される。本実験に用いる流動抵抗低減用の界面活性剤としては、環境負荷の小さい非イオン性界面活性剤を採用し、ワイヤーコイル形状（素線径、ピッチおよび長さ）や界面活性剤添加水の流速が直円管内の熱伝達促進に及ぼす影響の検討を行うものである。 kn-abstract=This paper has dealt with the heat transfer enhancement of flowing water with flow drag reduction additive into a heat transfer tube by inserting wire coils. The non-ion type surfactant was used as the additive to decrease the pipe flow resistance for the heat energy transport system. However, the decrease in the flow resistance was allowed to reduce the heat transfer coefficient in the heat transfer tube. Some kinds of wire coils having different diameters were tried to enhance the heat transfer in the heat transfer tube. The effects of wire coils on the pipe friction and the heat transfer coefficients were elucidated under various experimental parameters of flow velocity, wire coil diameter, pitch and length. en-copyright= kn-copyright= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=1 ORCID= en-aut-name=HarukiNaoto en-aut-sei=Haruki en-aut-mei=Naoto kn-aut-name=春木直人 kn-aut-sei=春木 kn-aut-mei=直人 aut-affil-num=2 ORCID= en-aut-name=NakataToru en-aut-sei=Nakata en-aut-mei=Toru kn-aut-name=中田達 kn-aut-sei=中田 kn-aut-mei=達 aut-affil-num=3 ORCID= en-aut-name=HoribeAkihiko en-aut-sei=Horibe en-aut-mei=Akihiko kn-aut-name=堀部明彦 kn-aut-sei=堀部 kn-aut-mei=明彦 aut-affil-num=4 ORCID= en-aut-name=FurumotoNaoyuki en-aut-sei=Furumoto en-aut-mei=Naoyuki kn-aut-name=古本直行 kn-aut-sei=古本 kn-aut-mei=直行 aut-affil-num=5 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤健次 kn-aut-sei=佐藤 kn-aut-mei=健次 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 affil-num=6 en-affil= kn-affil=岡山大学 en-keyword=Surfactant kn-keyword=Surfactant en-keyword=Flow Drag Reduction kn-keyword=Flow Drag Reduction en-keyword=Heat Transfer Enhancement kn-keyword=Heat Transfer Enhancement en-keyword=Wire Coil kn-keyword=Wire Coil en-keyword=Water Flow kn-keyword=Water Flow END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=702 article-no= start-page=573 end-page=580 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200502 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Flow Drag and Heat Transfer Characteristics of Organic Brine with Drag Reduction Surfactant in a Straight Pipe kn-title=直円管内を流動する界面活性剤添加有機プラインの流動抵抗と熱伝達挙動 en-subtitle= kn-subtitle= en-abstract=近年、ビルの空調システムや大規模工場および地域熱供給システム等の熱エネルギー輸送系において、水系の熱輸送媒体に流動抵抗減剤（界面活性剤、鎖状高分子等）の添加による流動抵抗減効果（乱流の層流化:いわゆるトムズ効果）を利用した省エネルギー技術が注目されている。一般に、流動抵抗低減効果を熱エネルギー輸送系に適用した場合、熱輸送媒体の輸送ポンプ動力の低減効果そして壁面熱伝導の低下による配管からの熱損失低減効果により、熱エネルギー輸送の効率化を図ることができる。例えば、川口らはこのような流動抵抗低減効果を用いることによって、熱交換器を用いた熱エネルギー輸送システム全体のエクセルギ効率が約70%改善されると試算している。一方で、壁面熱伝達の低減効果は、熱エネルギー利用のための熱交換器性能の低下をもたらす点が指摘されている。現在までに、流動抵抗低減効果を用いた水系熱輸送システムの実用化に向けて、様々な流動抵抗低減剤を用いた研究が盛んに行われている。特に非イオン系アミン系界面活性剤は、環境負荷が小さい水系輸送用流動抵抗低減剤として注目されている。本研究においては、低温熱輸送媒体としてのブラインの循環系搬送動力負荷が大きいことに着目し、その搬送動力低減に界面活性剤による流動抵抗低減効果を検討するものである。一般にブライン循環系には、有機系のエチレングリコールや無機系の塩化カルシウム等の水溶液が使用されている。しかしながら、現状では、ブライン輸送系に適した流動抵抗低減用界面活性剤の選定やその粘性評価に関する研究は現在徐々に行われ始めているが、未だ十分な結論は得られていないようである。本研究は、流動抵抗低減用界面活性剤の選定と、それを有機系ブライン（エチレングリコール水溶液）に添加した場合の流動抵抗と熱伝導特性の解明実験的に行うものである。実験では、界面活性剤添加濃度、ブライン濃度およびブライン温度を実験因子とした粘度の測定、そして水平円管内を流動する界面活性剤添加ブラインの流動抵抗および熱伝達に関する測定を行い、それらの諸特性を明らかにするものである。 kn-abstract=The flow drag and heat transfer reduction effects of brine flow with drag reduction surfactants have been investigated from the viewpoint of the effective energy consumption in an industrial cooling system. In this study, Oleyldihy-droxyetyl Amine Oxide (ODEAO) of non-ion surfactant was used as a drag reduction surfactant additive, and Ethylene Glycol (EG) was used as a organic brine. It was found that the viscosity of EG brine with ODEAO had the non-Newtonian behavior. The flow friction coefficient and mean forced convection heat transfer coefficient of the EG brine with ODEAO in a straight pipe were measured for each parameter of concentration of EG, concentration of ODEAO and temperature of the brine with ODEAO. The obtained experimental results indicated that the EG brine with ODEAO exerted an influence on the flow drag and heat transfer reduction. en-copyright= kn-copyright= en-aut-name=HarukiNaoto en-aut-sei=Haruki en-aut-mei=Naoto kn-aut-name=春木直人 kn-aut-sei=春木 kn-aut-mei=直人 aut-affil-num=1 ORCID= en-aut-name=InabaHideo en-aut-sei=Inaba en-aut-mei=Hideo kn-aut-name=稲葉英男 kn-aut-sei=稲葉 kn-aut-mei=英男 aut-affil-num=2 ORCID= en-aut-name=HoribeAkihiko en-aut-sei=Horibe en-aut-mei=Akihiko kn-aut-name=堀部明彦 kn-aut-sei=堀部 kn-aut-mei=明彦 aut-affil-num=3 ORCID= en-aut-name=TanakaShinji en-aut-sei=Tanaka en-aut-mei=Shinji kn-aut-name=田中真司 kn-aut-sei=田中 kn-aut-mei=真司 aut-affil-num=4 ORCID= en-aut-name=NakataToru en-aut-sei=Nakata en-aut-mei=Toru kn-aut-name=中田達 kn-aut-sei=中田 kn-aut-mei=達 aut-affil-num=5 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤健次 kn-aut-sei=佐藤 kn-aut-mei=健次 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 affil-num=6 en-affil= kn-affil=岡山大学 en-keyword=Flow Drag Reduction Effect kn-keyword=Flow Drag Reduction Effect en-keyword=Surfactant kn-keyword=Surfactant en-keyword=Organic Brine kn-keyword=Organic Brine en-keyword=Flow Friction Coefficient kn-keyword=Flow Friction Coefficient en-keyword=Heat Transfer Coefficient kn-keyword=Heat Transfer Coefficient END start-ver=1.4 cd-journal=joma no-vol=119 cd-vols= no-issue=1 article-no= start-page=57 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of oral morphine for pain relief of peripheral arterial disease kn-title=末梢血行障害による虚血性疼痛に対するモルヒネ内服の効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Peripheral arterial disease often causes ischemic ulcers due to impaired blood flow and consequentially induces intractable pain. For these patients, we have recently begun to administer morphine orally. In this study, we retrospectively examined the effects of oral morphine for the relief of pain caused by peripheral arterial disease. Oral morphine was administered to 17 cases of peripheral arterial disease between January, 2004 and February, 2006. The initial dosage was 5 mg or 10 mg, started on an as-needed basis. After the daily dosage of morphine became constant, we divided the dosage into four or six times a day and administered it regularly. With the exception of one case, a small amount of oral morphine, from 20 mg to 70 mg a day, could alleviate patient's pain. Eight cases had side effects such as nausea, constipation or drowsiness. Oral morphine is effective for pain relief of peripheral arterial disease patients. However, now in Japan, oral morphine, which we can prescribe for those patients with insurance, has a shorter duration of action, so we need to administer slow-release morphine. Oral morphine must be administered carefully because many peripheral arterial disease patients have cardiac disease or renal dysfunction as complications. en-copyright= kn-copyright= en-aut-name=NishieHiroyuki en-aut-sei=Nishie en-aut-mei=Hiroyuki kn-aut-name=西江宏行 kn-aut-sei=西江 kn-aut-mei=宏行 aut-affil-num=1 ORCID= en-aut-name=MizobuchiSatoshi en-aut-sei=Mizobuchi en-aut-mei=Satoshi kn-aut-name=溝渕知司 kn-aut-sei=溝渕 kn-aut-mei=知司 aut-affil-num=2 ORCID= en-aut-name=MatsusakiTakashi en-aut-sei=Matsusaki en-aut-mei=Takashi kn-aut-name=松崎孝 kn-aut-sei=松崎 kn-aut-mei=孝 aut-affil-num=3 ORCID= en-aut-name=MiyakeAsako en-aut-sei=Miyake en-aut-mei=Asako kn-aut-name=三宅麻子 kn-aut-sei=三宅 kn-aut-mei=麻子 aut-affil-num=4 ORCID= en-aut-name=KakuRyuji en-aut-sei=Kaku en-aut-mei=Ryuji kn-aut-name=賀来隆治 kn-aut-sei=賀来 kn-aut-mei=隆治 aut-affil-num=5 ORCID= en-aut-name=IshikawaShinichi en-aut-sei=Ishikawa en-aut-mei=Shinichi kn-aut-name=石川慎一 kn-aut-sei=石川 kn-aut-mei=慎一 aut-affil-num=6 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name=佐藤健治 kn-aut-sei=佐藤 kn-aut-mei=健治 aut-affil-num=7 ORCID= en-aut-name=MatsumiMasaki en-aut-sei=Matsumi en-aut-mei=Masaki kn-aut-name=松三昌樹 kn-aut-sei=松三 kn-aut-mei=昌樹 aut-affil-num=8 ORCID= en-aut-name=KiyoshiMorita en-aut-sei=Kiyoshi en-aut-mei=Morita kn-aut-name=森田潔 kn-aut-sei=森田 kn-aut-mei=潔 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=2 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=3 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=4 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=5 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=6 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=7 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=8 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 affil-num=9 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 麻酔科蘇生科 en-keyword=末梢血行障害 (peripheral arterial disease) kn-keyword=末梢血行障害 (peripheral arterial disease) en-keyword=モルヒネ (oral morphine) kn-keyword=モルヒネ (oral morphine) en-keyword=疼痛管理 (pain management) kn-keyword=疼痛管理 (pain management) en-keyword=虚血性潰瘍 (ischemic ulcer) kn-keyword=虚血性潰瘍 (ischemic ulcer) END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=6 article-no= start-page=323 end-page=329 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=201412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Mean Lung Pressure during Adult High-Frequency Oscillatory Ventilation: An Experimental Study Using a Lung Model en-subtitle= kn-subtitle= en-abstract= kn-abstract=In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV. en-copyright= kn-copyright= en-aut-name=HirayamaTakahiro en-aut-sei=Hirayama en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NaganoOsamu en-aut-sei=Nagano en-aut-mei=Osamu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ShibaNaoki en-aut-sei=Shiba en-aut-mei=Naoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YumotoTetsuya en-aut-sei=Yumoto en-aut-mei=Tetsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SatoKeiji en-aut-sei=Sato en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TeradoMichihisa en-aut-sei=Terado en-aut-mei=Michihisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=UgawaToyomu en-aut-sei=Ugawa en-aut-mei=Toyomu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IchibaShingo en-aut-sei=Ichiba en-aut-mei=Shingo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=UjikeYoshihito en-aut-sei=Ujike en-aut-mei=Yoshihito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Disaster and Emergency Medicine, Kochi University affil-num=3 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=5 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=7 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=8 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=9 en-affil= kn-affil=Department of Emergency and Critical Care Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences en-keyword=HFOV kn-keyword=HFOV en-keyword=mean lung pressure kn-keyword=mean lung pressure en-keyword=mean airway pressure kn-keyword=mean airway pressure END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=6 article-no= start-page=375 end-page=378 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=201412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Management of Lacerated and Swollen Tongue after Convulsive Seizure with a Mouth Protector: Interprofessional Collaboration Including Dentists in Intensive Care en-subtitle= kn-subtitle= en-abstract= kn-abstract=We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care. en-copyright= kn-copyright= en-aut-name=YamanakaReiko en-aut-sei=Yamanaka en-aut-mei=Reiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SogaYoshihiko en-aut-sei=Soga en-aut-mei=Yoshihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MoriyaYoshie en-aut-sei=Moriya en-aut-mei=Yoshie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OkuiAkemi en-aut-sei=Okui en-aut-mei=Akemi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakeuchiTetsuo en-aut-sei=Takeuchi en-aut-mei=Tetsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MorimatsuHiroshi en-aut-sei=Morimatsu en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MoritaManabu en-aut-sei=Morita en-aut-mei=Manabu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Division of Hospital Dentistry, Central Clinical Department, Okayama University Hospital affil-num=2 en-affil= kn-affil=Division of Hospital Dentistry, Central Clinical Department, Okayama University Hospital affil-num=3 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=4 en-affil= kn-affil=Division of Hospital Dentistry, Central Clinical Department, Okayama University Hospital affil-num=5 en-affil= kn-affil=Division of Dental Laboratory, Medical Support Department, Okayama University Hospital affil-num=6 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=7 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=8 en-affil= kn-affil=Division of Hospital Dentistry, Central Clinical Department, Okayama University Hospital en-keyword=mouth protector kn-keyword=mouth protector en-keyword=tongue laceration kn-keyword=tongue laceration END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=6 article-no= start-page=339 end-page=348 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=201412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Living Will Interest and Preferred End-of-life Care and Death Locations among Japanese Adults 50 and over: A Population-based Survey en-subtitle= kn-subtitle= en-abstract= kn-abstract=The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ｧ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care. en-copyright= kn-copyright= en-aut-name=NishieHiroyuki en-aut-sei=Nishie en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MizobuchiSatoshi en-aut-sei=Mizobuchi en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SuzukiEtsuji en-aut-sei=Suzuki en-aut-mei=Etsuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TodaYuichiro en-aut-sei=Toda en-aut-mei=Yuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MatsuokaJunji en-aut-sei=Matsuoka en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MorimatsuHiroshi en-aut-sei=Morimatsu en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=2 en-affil= kn-affil=Department of Anesthesiology and Perioperative Medicine, Kobe University Graduate School of Medicine affil-num=3 en-affil= kn-affil=Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=5 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital affil-num=6 en-affil= kn-affil=Department of Palliative Care Medicine, Okayama University Hospital affil-num=7 en-affil= kn-affil=Department of Anesthesiology and Resuscitology, Okayama University Hospital en-keyword=advance healthcare directive kn-keyword=advance healthcare directive en-keyword=living will kn-keyword=living will en-keyword=end-of-life care kn-keyword=end-of-life care en-keyword=palliative care unit kn-keyword=palliative care unit en-keyword=place of death kn-keyword=place of death END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=6 article-no= start-page=743 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210603 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Parieto-Occipital Alpha and Low-Beta EEG Power Reflect Sense of Agency en-subtitle= kn-subtitle= en-abstract= kn-abstract=The sense of agency (SoA) is part of psychophysiological modules related to the self. Disturbed SoA is found in several clinical conditions, hence understanding the neural correlates of the SoA is useful for the diagnosis and determining the proper treatment strategies. Although there are several neuroimaging studies on SoA, it is desirable to translate the knowledge to more accessible and inexpensive EEG-based biomarkers for the sake of applicability. However, SoA has not been widely investigated using EEG. To address this issue, we designed an EEG experiment on healthy adults (n = 15) to determine the sensitivity of EEG on the SoA paradigm using hand movement with parametrically delayed visual feedback. We calculated the power spectral density over the traditional EEG frequency bands for ten delay conditions relative to no delay condition. Independent component analysis and equivalent current dipole modeling were applied to address artifact rejection, volume conduction, and source localization to determine the effect of interest. The results revealed that the alpha and low-beta EEG power increased in the parieto-occipital regions in proportion to the reduced SoA reported by the subjects. We conclude that the parieto-occipital alpha and low-beta EEG power reflect the sense of agency. en-copyright= kn-copyright= en-aut-name=Bu-OmerHani M. en-aut-sei=Bu-Omer en-aut-mei=Hani M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=GofukuAkio en-aut-sei=Gofuku en-aut-mei=Akio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SatoKenji en-aut-sei=Sato en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MiyakoshiMakoto en-aut-sei=Miyakoshi en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Anesthesiology and Intensive Care Medicine, Kawasaki Medical School kn-affil= affil-num=4 en-affil=Swartz Center for Computational Neuroscience, Institute for Neural Computation, University of California San Diego kn-affil= en-keyword=sense of agency kn-keyword=sense of agency en-keyword=electroencephalography (EEG) kn-keyword=electroencephalography (EEG) en-keyword=mirror visual feedback kn-keyword=mirror visual feedback en-keyword=virtual reality kn-keyword=virtual reality en-keyword=delayed visual feedback kn-keyword=delayed visual feedback END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=24 article-no= start-page=6184 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20221214 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The Effect of Pleural Effusion on Prognosis in Patients with Non-Small Cell Lung Cancer Undergoing Immunochemotherapy: A Retrospective Observational Study en-subtitle= kn-subtitle= en-abstract= kn-abstract=Simple Summary Minimal data exists on pleural effusion (PE) for non-small cell lung cancer (NSCLC) patients undergoing combined ICI and chemotherapy. We retrospectively investigated how PE affects survival outcomes in patients with NSCLC undergoing this combined therapy. We identified 478 patients who underwent combined ICI therapy and chemotherapy; 357 patients did not have PE, and 121 patients did have PE. Patients with PE had significantly shorter progression-free survival and overall survival than those without PE. In addition, bevacizumab-containing regimens did not improve the survival outcomes for patients with PE. In conclusion, PE was associated with poor outcomes among patients with NSCLC undergoing combined ICI therapy and chemotherapy. Objectives: Combined immune checkpoint inhibitor (ICI) therapy and chemotherapy has become the standard treatment for advanced non-small-cell lung cancer (NSCLC). Pleural effusion (PE) is associated with poor outcomes among patients with NSCLC undergoing chemotherapy. However, minimal data exists on PE for patients undergoing combined ICI and chemotherapy. Therefore, we investigated how PE affects survival outcomes in patients with NSCLC undergoing this combined therapy. Methods: We identified patients with advanced NSCLC undergoing chemotherapy and ICI therapy from the Okayama Lung Cancer Study Group-Immune Chemotherapy Database (OLCSG-ICD) between December 2018 and December 2020; the OLCSG-ICD includes the clinical data of patients with advanced NSCLC from 13 institutions. Then, we analyzed the treatment outcomes based on the presence of PE. Results: We identified 478 patients who underwent combined ICI therapy and chemotherapy; 357 patients did not have PE, and 121 patients did have PE. Patients with PE had significantly shorter progression-free survival (PFS) and overall survival (OS) than those without PE (median PFS: 6.2 months versus 9.1 months; p < 0.001; median OS: 16.4 months versus 27.7 months; p < 0.001). The negative effect of PE differed based on the patient's programmed cell death-ligand 1 (PD-L1) expression status; with the effect being more evident in patients with high PD-L1 expression. In addition, PFS and OS did not differ between patients who did and did not undergo bevacizumab treatment; thus, bevacizumab-containing regimens did not improve the survival outcomes for patients with PE. Conclusion: PE is associated with poor outcomes among patients with NSCLC undergoing combined ICI therapy and chemotherapy. en-copyright= kn-copyright= en-aut-name=NishimuraTomoka en-aut-sei=Nishimura en-aut-mei=Tomoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IchiharaEiki en-aut-sei=Ichihara en-aut-mei=Eiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YokoyamaToshihide en-aut-sei=Yokoyama en-aut-mei=Toshihide kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=InoueKoji en-aut-sei=Inoue en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TamuraTomoki en-aut-sei=Tamura en-aut-mei=Tomoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SatoKen en-aut-sei=Sato en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OdaNaohiro en-aut-sei=Oda en-aut-mei=Naohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KanoHirohisa en-aut-sei=Kano en-aut-mei=Hirohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KishinoDaizo en-aut-sei=Kishino en-aut-mei=Daizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KawaiHaruyuki en-aut-sei=Kawai en-aut-mei=Haruyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=InoueMasaaki en-aut-sei=Inoue en-aut-mei=Masaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OchiNobuaki en-aut-sei=Ochi en-aut-mei=Nobuaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=FujimotoNobukazu en-aut-sei=Fujimoto en-aut-mei=Nobukazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=IchikawaHirohisa en-aut-sei=Ichikawa en-aut-mei=Hirohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=AndoChihiro en-aut-sei=Ando en-aut-mei=Chihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=HottaKatsuyuki en-aut-sei=Hotta en-aut-mei=Katsuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=MaedaYoshinobu en-aut-sei=Maeda en-aut-mei=Yoshinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=KiuraKatsuyuki en-aut-sei=Kiura en-aut-mei=Katsuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= affil-num=1 en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Respiratory Medicine, Ohara Healthcare Foundation, Kurashiki Central Hospital kn-affil= affil-num=4 en-affil=Department of Respiratory Medicine, Ehime Prefectural Central Hospital kn-affil= affil-num=5 en-affil=Department of Respiratory Medicine, NHO Iwakuni Clinical Center kn-affil= affil-num=6 en-affil=Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center kn-affil= affil-num=7 en-affil=Department of Internal Medicine, Fukuyama City Hospital kn-affil= affil-num=8 en-affil=Department of Respiratory Medicine, Japanese Red Cross Okayama Hospital kn-affil= affil-num=9 en-affil=Department of Respiratory Medicine, Japanese Red Cross Society Himeji Hospital kn-affil= affil-num=10 en-affil=Department of Internal Medicine, Okayama Saiseikai General Hospital kn-affil= affil-num=11 en-affil=Department of Chest Surgery, Shimonoseki City Hospital kn-affil= affil-num=12 en-affil=Department of General Internal Medicine 4, Kawasaki Medical School kn-affil= affil-num=13 en-affil=Department of Respiratory Medicine, Okayama Rosai Hospital kn-affil= affil-num=14 en-affil=Department of Respiratory Medicine, KKR Takamatsu Hospital kn-affil= affil-num=15 en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=16 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital kn-affil= affil-num=17 en-affil=Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=18 en-affil=Department of Allergy and Respiratory Medicine, Okayama University Hospital kn-affil= en-keyword=pleural effusion kn-keyword=pleural effusion en-keyword=non-small cell carcinoma kn-keyword=non-small cell carcinoma en-keyword=immune checkpoint inhibitors kn-keyword=immune checkpoint inhibitors END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=65 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=202302 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effect of a Cyclooxygenase-2 Inhibitor in Combination with (−)-Epigallocatechin Gallate or Polyphenon E on Cisplatin-Induced Lung Tumorigenesis in A/J Mice en-subtitle= kn-subtitle= en-abstract= kn-abstract=We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors. en-copyright= kn-copyright= en-aut-name=SatoKen en-aut-sei=Sato en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakigawaNagio en-aut-sei=Takigawa en-aut-mei=Nagio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KuboToshio en-aut-sei=Kubo en-aut-mei=Toshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KatayamaHideki en-aut-sei=Katayama en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KishinoDaizo en-aut-sei=Kishino en-aut-mei=Daizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkadaToshiaki en-aut-sei=Okada en-aut-mei=Toshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HisamotoAkiko en-aut-sei=Hisamoto en-aut-mei=Akiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MimotoJunko en-aut-sei=Mimoto en-aut-mei=Junko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=OchiNobuaki en-aut-sei=Ochi en-aut-mei=Nobuaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YoshinoTadashi en-aut-sei=Yoshino en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=UeokaHiroshi en-aut-sei=Ueoka en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=TanimotoMitsune en-aut-sei=Tanimoto en-aut-mei=Mitsune kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=MaedaYoshionobu en-aut-sei=Maeda en-aut-mei=Yoshionobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=KiuraKatsuyuki en-aut-sei=Kiura en-aut-mei=Katsuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of General Internal Medicine 4, Kawasaki Medical School kn-affil= affil-num=3 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Medicine, Yamaguchi-Ube Medical Center kn-affil= affil-num=5 en-affil=Department of Medicine, Yamaguchi-Ube Medical Center kn-affil= affil-num=6 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of General Internal Medicine 4, Kawasaki Medical School kn-affil= affil-num=10 en-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Medicine, Yamaguchi-Ube Medical Center kn-affil= affil-num=12 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=14 en-affil=Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=celecoxib kn-keyword=celecoxib en-keyword=cisplatin kn-keyword=cisplatin en-keyword=EGCG kn-keyword=EGCG en-keyword=lung tumor kn-keyword=lung tumor en-keyword=polyphenon E kn-keyword=polyphenon E END