ID | 60799 |
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Author |
Tsukioki, Takahiro
Department of Breast and Endocrine Surgery, Okayama University Hospital
Shien, Tadahiko
Department of Breast and Endocrine Surgery, Okayama University Hospital
ORCID
Kaken ID
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Ohtani, Yusuke
Department of Breast and Endocrine Surgery, Okayama University Hospital
Fujihara, Miwa
Department of Breast and Endocrine Surgery, Okayama University Hospital
Suzuki, Yoko
Department of Breast and Endocrine Surgery, Okayama University Hospital
ORCID
Kajihara, Yukiko
Department of Breast and Endocrine Surgery, Okayama University Hospital
Hatono, Minami
Department of Breast and Endocrine Surgery, Okayama University Hospital
Kawada, Kengo
Department of Breast and Endocrine Surgery, Okayama University Hospital
Kochi, Mariko
Department of Breast and Endocrine Surgery, Okayama University Hospital
Iwamoto, Takayuki
Department of Breast and Endocrine Surgery, Okayama University Hospital
Kaken ID
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Ikeda, Hirokuni
Department of Breast and Endocrine Surgery, Okayama University Hospital
Taira, Naruto
Department of Breast and Endocrine Surgery, Okayama University Hospital
Kaken ID
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Doihara, Hiroyoshi
Department of Breast and Endocrine Surgery, Okayama University Hospital
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Abstract | Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC.
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Keywords | differentiated thyroid carcinoma
juvenile
children
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Amo Type | Original Article
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Publication Title |
Acta Medica Okayama
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Published Date | 2020-10
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Volume | volume74
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Issue | issue5
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Publisher | Okayama University Medical School
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Start Page | 401
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End Page | 406
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School
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File Version | publisher
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Refereed |
True
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