Author Kitagawa, Kohei| Matsunaga, Hisashi| Sendo, Toshiaki|
Published Date 2012-04-01
Publication Title 岡山医学会雑誌
Volume volume124
Issue issue1
Content Type Journal Article
Author Nishimiya, Yusuke| Konuma, Toshimitsu| Tasaka, Ken| Sendo, Toshiaki|
Published Date 2012-08-01
Publication Title 岡山医学会雑誌
Volume volume124
Issue issue2
Content Type Journal Article
Author Yamaji, Kazuhiko| Sendo, Toshiaki|
Published Date 2012-12-03
Publication Title 岡山医学会雑誌
Volume volume124
Issue issue3
Content Type Journal Article
Author Makita, Takashi| Kitamura, Yoshihisa| Sendo, Toshiaki|
Published Date 2013-04-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue1
Content Type Journal Article
Author Kuroda, Satoshi| Sendo, Toshiaki|
Published Date 2013-04-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue1
Content Type Journal Article
Author Kurata, Yasuko| Fujiwara, Satoko| Kajizono, Makoto| Aoyagi, Megumu| Kitamura, Yoshihisa| Sendo, Toshiaki|
Published Date 2013-08-01
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue2
Content Type Journal Article
Author Esumi, Satoru| Sagara, Hidenori| Nakamoto, Akihiko| Kawasaki, Yoichi| Gomita, Yutaka| Sendo, Toshiaki|
Published Date 2013-04-15
Publication Title Behavioural Brain Research
Volume volume243
Content Type Journal Article
JaLCDOI 10.18926/AMO/51868
FullText URL 67_5_319.pdf
Author Murakawa, Kiminaka| Sato, Tomoaki| Maeda, Yoshinobu| Kitamura, Yoshihisa| Tanimoto, Mitsune| Sendo, Toshiaki|
Abstract Graft-versus-host disease (GVHD) is a major concern in transplantation patients. Gut GVHD is accompanied by diarrhea, abdominal pain, and/or melena. Although oral treatment with corticosteroids (CSs) is effective in treating gut GVHD, it can cause adverse reactions that affect the entire body. Topical administration of CSs can be effective in treating diseases in which lesions are limited locally, because adverse reactions can then be alleviated. In this study, we examine and discuss an enteric-coated beclomethasone dipropionate (BDP) capsule (BDP-EC) formulated at Okayama University Hospital. The BDP-EC did not dissolve in solution 1 (pH1.2), and began disintegrating in solution 2 (pH6.8) after 5min, with a mean dissolution rate at 15min of 85%. We then used the capsule to treat a patient who developed gut GVHD after allogeneic hematopoietic stem cell transplantation. Clinically, the frequency of diarrhea decreased after BDP-EC administration. In addition, we were able to decrease the prednisolone equivalent dose. Symptoms associated with adverse reactions to BDP were not observed during the hospitalization period. These findings suggest that the administration of BDP-EC in the early stages of gut GVHD may allow a reduction in the initial doses of systemic CSs.
Keywords beclomethasone intestinal graft-versus-host disease enteric-coated capsule in-hospital formulation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2013-10
Volume volume67
Issue issue5
Publisher Okayama University Medical School
Start Page 319
End Page 324
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2013 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 24145732
Web of Science KeyUT 000325836100006
Author Esumi, Satoru| Sagara, Hidenori| Nakamoto, Akihiko| Kawasaki, Yoichi| Gomita, Yutaka| Sendo, Toshiaki|
Published Date 2013-12-02
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue3
Content Type Journal Article
Author Okazaki, Masatoshi| Sendo, Toshiaki|
Published Date 2013-12-02
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue3
Content Type Journal Article
Author Haruta, Yusuke| Kawasaki, Yoichi| Kitamura, Yoshihisa| Sendo, Toshiaki|
Published Date 2013-12-02
Publication Title 岡山医学会雑誌
Volume volume125
Issue issue3
Content Type Journal Article
Title Alternative Drug interaction (29. drug interaction of steroids)
FullText URL 126_59.pdf
Author Hayashi, Youko| Nawa, Hideki| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2014-04-01
Volume volume126
Issue issue1
Start Page 59
End Page 63
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language Japanese
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.59
Title Alternative Drug interaction (30. combination with therapeutic drugs for chronic pain)
FullText URL 126_159.pdf
Author Ogawa, Atsushi| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2014-08-01
Volume volume126
Issue issue2
Start Page 159
End Page 163
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.159
NAID 130004685269
Author Yamaji, Kazuhiko| Kawasaki, Yoichi| Yoshitome, Kei| Matsunaga, Hisashi| Sendo, Toshiaki|
Published Date 2012-10
Publication Title Biological & Pharmaceutical Bulletin
Volume volume35
Issue issue10
Content Type Journal Article
Author Hayashi, Keiichiro| Ueshima, Satoshi| Ouchida, Mamoru| Mashimo, Tomoji| Nishiki, Teiichi| Sendo, Toshiaki| Serikawa, Tadao| Matsui, Hideki| Ohmori, Iori|
Published Date 2011-05
Publication Title Epilepsia
Volume volume52
Issue issue5
Content Type Journal Article
JaLCDOI 10.18926/AMO/52893
FullText URL 68_5_255.pdf
Author Esumi, Satoru| Kawasaki, Yoichi| Gomita, Yutaka| Kitamura, Yoshihisa| Sendo, Toshiaki|
Abstract Motivation incorporates several psychological aspects that produce reward-related and learning behaviors. Although reward-related behavior is reported to be mediated by the dopaminergic reward pathway, the involvement of dopaminergic systems in motivated behavior has not been fully clarified. Several experimental methodologies for motivational behavior have been reported, but pharmacological characteristics seem to vary among these methodologies. In this review, we attempt to summarize three main concepts:(1) the relationship of dopamine neuron physiology with motivated behavior, (2) the pharmacological characteristics of the runway intracranial self-stimulation model, and (3) the behavioral distinction of disparate motivated behaviors.
Keywords motivation reward dopamine operant behavior intracranial self-stimulation
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2014-10
Volume volume68
Issue issue5
Publisher Okayama University Medical School
Start Page 255
End Page 262
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2014 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25338481
Web of Science KeyUT 000343269300001
Title Alternative Drug interaction (31. drug interaction in hormonal breast cancer therapy)
FullText URL 126_245.pdf
Author Masaoka, Yasuyuki| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2014-12-01
Volume volume126
Issue issue3
Start Page 245
End Page 248
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2014 岡山医学会
File Version publisher
DOI 10.4044/joma.126.245
NAID 130004903247
Title Alternative Drug interaction (32. Drug interaction in novel oral anticoagulants)
FullText URL 127_59.pdf
Author Ida, Hiromi| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2015-04-01
Volume volume127
Issue issue1
Start Page 59
End Page 61
ISSN 0030-1558
Related Url http://www.okayama-u.ac.jp/user/oma/
language Japanese
Copyright Holders Copyright (c) 2015 岡山医学会
File Version publisher
DOI 10.4044/joma.127.59
NAID 130005068338
Author Zamami, Yoshito| Koyama, Toshihiro| Aiba, Tetsuya| Amano, Manabu| Ando, Tetsuaki| Kurata, Naomi| Nawa, Hideki| Nakura, Hironori| Kitamura, Yoshihisa| Sendo, Toshiaki|
Published Date 2014
Publication Title 静脈経腸栄養
Volume volume29
Issue issue4
Content Type Journal Article
Title Alternative Drug interaction (33. Combination with antimicrobial agents)
FullText URL 127_151.pdf
Author Tasaka, Ken| Shiraishi, Naoko| Kitamura, Yoshihisa| Sendo, Toshiaki|
Publication Title 岡山医学会雑誌
Published Date 2015-08-03
Volume volume127
Issue issue2
Start Page 151
End Page 154
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.127.151
language Japanese
Copyright Holders Copyright (c) 2015 岡山医学会
File Version publisher
DOI 10.4044/joma.127.151
NAID 130005096260