Author Muranaka, Makoto| Hyodo, Isao| Okumura, Wataru| Oshiki, Toshiyuki|
Published Date 2011-04-30
Publication Title Catalysis Today
Volume volume164
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/AMO/60371
FullText URL 74_4_327.pdf
Author Yamamoto, Ken-ichi| Kagawa, Hiroko| Arimoto, Sakae| Tan, Xian Wen| Yasui, Kento| Oshiki, Toshiyuki| Sakaguchi, Masakiyo|
Abstract An increasing accumulation of microplastics and further degraded nanoplastics in our environment is suspected to have harmful effects on humans and animals. To clarify this problem, we tested the cytotoxicity of two types of plastic wrap on human cultured liver cells and mouse primary cultured liver cells. Alcohol extracts from plastic wrap, i.e., polyvinylidene chloride (PVDC), showed cytotoxic effects on the cells. Alcohol extracts of polyethylene (PE) wrap were not toxic. The commercially available PVDC wrap consists of vinylidene chloride, epoxidized soybean oil, epoxidized linseed oil as a stiffener and stabilizer; we sought to identify which component(s) are toxic. The epoxidized soybean oil and epoxidized linseed oil exerted strong cytotoxicity, but the plastic raw material itself, vinylidene chloride, did not. Our findings indicate that plastic wraps should be used with caution in order to prevent health risks.
Keywords plastic wrap plasticizer, cytotoxicity, liver cells in vitro
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-08
Volume volume74
Issue issue4
Publisher Okayama University Medical School
Start Page 327
End Page 334
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32843764
Web of Science KeyUT 000562508700008
NAID 120006880210
Author Oshiki, Toshiyuki|
Publication Title
Content Type Others
Author Oshiki, Toshiyuki|
Published Date 2007-03-24
Publication Title
Content Type Conference Paper
Author Oshiki, Toshiyuki|
Published Date 2011-02
Publication Title 化学経済
Volume volume58
Issue issue2
Content Type Article
Author 押木 俊之|
Publication Title
Content Type Others
Author 押木 俊之|
Publication Title
Content Type Others
Author Oshiki, Toshiyuki|
Published Date 2007-09-12
Publication Title
Content Type Conference Paper
Author Oshiki, Toshiyuki| Ishiduka, Akinori|
Published Date 2007-06-05
Publication Title
Content Type Conference Paper
Author Oshiki, Toshiyuki|
Publication Title
Content Type Others